IL191064A0 - Real time nucleic acid detection in vivo using protein complementation - Google Patents
Real time nucleic acid detection in vivo using protein complementationInfo
- Publication number
- IL191064A0 IL191064A0 IL191064A IL19106408A IL191064A0 IL 191064 A0 IL191064 A0 IL 191064A0 IL 191064 A IL191064 A IL 191064A IL 19106408 A IL19106408 A IL 19106408A IL 191064 A0 IL191064 A0 IL 191064A0
- Authority
- IL
- Israel
- Prior art keywords
- vivo
- nucleic acid
- real time
- acid detection
- time nucleic
- Prior art date
Links
- 238000001514 detection method Methods 0.000 title 1
- 238000001727 in vivo Methods 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 238000003157 protein complementation Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/682—Signal amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2522/00—Reaction characterised by the use of non-enzymatic proteins
- C12Q2522/10—Nucleic acid binding proteins
- C12Q2522/101—Single or double stranded nucleic acid binding proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2561/00—Nucleic acid detection characterised by assay method
- C12Q2561/107—Enzyme complementation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2561/00—Nucleic acid detection characterised by assay method
- C12Q2561/113—Real time assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/107—Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73074605P | 2005-10-27 | 2005-10-27 | |
| PCT/US2006/042210 WO2007050979A2 (en) | 2005-10-27 | 2006-10-27 | Real time nucleic acid detection in vivo using protein complementation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL191064A0 true IL191064A0 (en) | 2008-12-29 |
Family
ID=37968606
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL191064A IL191064A0 (en) | 2005-10-27 | 2008-04-27 | Real time nucleic acid detection in vivo using protein complementation |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20090029370A1 (https=) |
| EP (1) | EP1954828A2 (https=) |
| JP (1) | JP2009513141A (https=) |
| KR (1) | KR20080070837A (https=) |
| CN (1) | CN101365805A (https=) |
| AU (1) | AU2006305901A1 (https=) |
| CA (1) | CA2627410A1 (https=) |
| IL (1) | IL191064A0 (https=) |
| WO (1) | WO2007050979A2 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7662554B2 (en) * | 2002-10-09 | 2010-02-16 | The Trustees Of Boston University | Nucleic acid supported protein complementation |
| EP1948825A2 (en) * | 2005-10-27 | 2008-07-30 | The Trustees Of Boston University | Activated split-polypeptides and methods for their production and use |
| KR20090073255A (ko) * | 2006-10-27 | 2009-07-02 | 트르스티스 오브 보스톤 유니버시티 | 질병, 악성 종양 및 장애를 치료하기 위한 표적화 분열 생체 분자성 접합체, 및 그의 생성 방법 |
| AU2008308457A1 (en) * | 2007-10-04 | 2009-04-09 | Halcyon Molecular | Sequencing nucleic acid polymers with electron microscopy |
| WO2011135040A1 (en) | 2010-04-30 | 2011-11-03 | F. Hoffmann-La Roche Ag | Fluorescent antibody fusion protein, its production and use |
| CN106868157B (zh) * | 2017-03-17 | 2019-08-27 | 广东省生态环境技术研究所 | 一种金黄色葡萄球菌的检测方法及检测试剂盒 |
| CN106868158B (zh) * | 2017-03-17 | 2019-08-27 | 广东省生态环境技术研究所 | 一种沙门氏菌的检测方法及检测试剂盒 |
| WO2019018423A1 (en) * | 2017-07-17 | 2019-01-24 | The Broad Institute, Inc. | NEW TYPE VI CRISPR ORTHOLOGISTS AND ASSOCIATED SYSTEMS |
| CN108267595A (zh) * | 2017-11-27 | 2018-07-10 | 南京天纵易康生物科技股份有限公司 | 一种基于双分子荧光互补技术的Myo检测试剂盒、制备及使用方法 |
| WO2020018509A2 (en) * | 2018-07-16 | 2020-01-23 | Massachusetts Institute Of Technology | Rna tickertape for recording transcriptional histories of cells |
| JPWO2021010442A1 (https=) * | 2019-07-16 | 2021-01-21 | ||
| CN110455756B (zh) * | 2019-07-26 | 2022-03-29 | 重庆工商大学 | 一种同时检测二价铅离子和二价铜离子的方法 |
| CN114252622A (zh) * | 2020-09-23 | 2022-03-29 | 中国科学院大连化学物理研究所 | 一种体外筛选新型冠状病毒抑制剂的方法 |
| CN113092461B (zh) * | 2021-04-09 | 2023-08-22 | 四川大学华西医院 | 一种均相二维可视化/荧光分析方法及应用 |
| CN113504274B (zh) * | 2021-07-20 | 2023-11-21 | 郑州轻工业大学 | 一种共价有机骨架材料及其制备方法和应用，适配体传感器及其制备方法 |
| CN115855920B (zh) * | 2022-08-29 | 2026-04-14 | 江苏科技大学 | 智能手机APP结合DSN酶微流体芯片比色检测miRNA-21的方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2075858C (en) * | 1991-08-15 | 1998-05-19 | Scott J. Eisenbeis | Detection of complementary nucleotide sequences |
| JPH08500965A (ja) * | 1992-05-22 | 1996-02-06 | デイナ ファーバー キャンサー インスチチュート | ハイブリッドウイルス発現ベクター，その使用および新規アッセイ |
| AU7401394A (en) * | 1993-07-20 | 1995-02-20 | University Of Massachusetts Medical Center | In vivo nucleic acid hybridization method |
| US5854033A (en) * | 1995-11-21 | 1998-12-29 | Yale University | Rolling circle replication reporter systems |
| CA2196496A1 (en) * | 1997-01-31 | 1998-07-31 | Stephen William Watson Michnick | Protein fragment complementation assay for the detection of protein-protein interactions |
| US6294330B1 (en) * | 1997-01-31 | 2001-09-25 | Odyssey Pharmaceuticals Inc. | Protein fragment complementation assays for the detection of biological or drug interactions |
| EP0878552A1 (en) * | 1997-05-13 | 1998-11-18 | Erasmus Universiteit Rotterdam | Molecular detection of chromosome aberrations |
| US7166424B2 (en) * | 1998-02-02 | 2007-01-23 | Odyssey Thera Inc. | Fragments of fluorescent proteins for protein fragment complementation assays |
| US6287772B1 (en) * | 1998-04-29 | 2001-09-11 | Boston Probes, Inc. | Methods, kits and compositions for detecting and quantitating target sequences |
| AU766499B2 (en) * | 1998-06-23 | 2003-10-16 | Medical Research Council | Structured antisense nucleic acid molecules |
| US8148110B2 (en) * | 1999-03-15 | 2012-04-03 | The Board Of Trustees Of The Leland Stanford Junior University | Detection of molecular interactions by β-lactamase reporter fragment complementation |
| US7306904B2 (en) * | 2000-02-18 | 2007-12-11 | Olink Ab | Methods and kits for proximity probing |
| AU781992B2 (en) * | 2000-04-04 | 2005-06-23 | Medical Research Council | Methods involving induced dimerisation by cellular components |
| US6951947B2 (en) * | 2000-07-13 | 2005-10-04 | The Scripps Research Institute | Labeled peptides, proteins and antibodies and processes and intermediates useful for their preparation |
| GB0226727D0 (en) * | 2002-11-15 | 2002-12-24 | Medical Res Council | Intrabodies |
| US7662554B2 (en) * | 2002-10-09 | 2010-02-16 | The Trustees Of Boston University | Nucleic acid supported protein complementation |
| GB0226729D0 (en) * | 2002-11-15 | 2002-12-24 | Medical Res Council | Intracellular antibodies |
| EP1877583A2 (en) * | 2005-05-05 | 2008-01-16 | Arizona Board of Regents on behalf of the Unversity of Arizona | Sequence enabled reassembly (seer) - a novel method for visualizing specific dna sequences |
| EP1948825A2 (en) * | 2005-10-27 | 2008-07-30 | The Trustees Of Boston University | Activated split-polypeptides and methods for their production and use |
-
2006
- 2006-10-27 US US12/091,682 patent/US20090029370A1/en not_active Abandoned
- 2006-10-27 KR KR1020087012697A patent/KR20080070837A/ko not_active Withdrawn
- 2006-10-27 JP JP2008538055A patent/JP2009513141A/ja active Pending
- 2006-10-27 WO PCT/US2006/042210 patent/WO2007050979A2/en not_active Ceased
- 2006-10-27 AU AU2006305901A patent/AU2006305901A1/en not_active Abandoned
- 2006-10-27 EP EP06827001A patent/EP1954828A2/en not_active Withdrawn
- 2006-10-27 CN CNA2006800498010A patent/CN101365805A/zh active Pending
- 2006-10-27 CA CA002627410A patent/CA2627410A1/en not_active Abandoned
-
2008
- 2008-04-27 IL IL191064A patent/IL191064A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2006305901A1 (en) | 2007-05-03 |
| WO2007050979A2 (en) | 2007-05-03 |
| CN101365805A (zh) | 2009-02-11 |
| US20090029370A1 (en) | 2009-01-29 |
| KR20080070837A (ko) | 2008-07-31 |
| JP2009513141A (ja) | 2009-04-02 |
| EP1954828A2 (en) | 2008-08-13 |
| WO2007050979A3 (en) | 2007-07-26 |
| CA2627410A1 (en) | 2007-05-03 |
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