IL185109A0 - Phuman t2r receptors for acetaminophen, ranitidine, strychnine, and denatonium, and related assays for identifying human bitter taste modulators - Google Patents

Phuman t2r receptors for acetaminophen, ranitidine, strychnine, and denatonium, and related assays for identifying human bitter taste modulators

Info

Publication number
IL185109A0
IL185109A0 IL185109A IL18510907A IL185109A0 IL 185109 A0 IL185109 A0 IL 185109A0 IL 185109 A IL185109 A IL 185109A IL 18510907 A IL18510907 A IL 18510907A IL 185109 A0 IL185109 A0 IL 185109A0
Authority
IL
Israel
Prior art keywords
phuman
denatonium
strychnine
ranitidine
acetaminophen
Prior art date
Application number
IL185109A
Other languages
English (en)
Original Assignee
Senomyx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senomyx Inc filed Critical Senomyx Inc
Publication of IL185109A0 publication Critical patent/IL185109A0/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Endocrinology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL185109A 2005-02-08 2007-08-07 Phuman t2r receptors for acetaminophen, ranitidine, strychnine, and denatonium, and related assays for identifying human bitter taste modulators IL185109A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65055505P 2005-02-08 2005-02-08
PCT/US2006/002509 WO2006086150A2 (en) 2005-02-08 2006-01-06 Phuman t2r receptors for acetaminophen, ranitidine, strychnine and denatonium and related assays for identifying human bitter taste modulators

Publications (1)

Publication Number Publication Date
IL185109A0 true IL185109A0 (en) 2007-12-03

Family

ID=36793558

Family Applications (1)

Application Number Title Priority Date Filing Date
IL185109A IL185109A0 (en) 2005-02-08 2007-08-07 Phuman t2r receptors for acetaminophen, ranitidine, strychnine, and denatonium, and related assays for identifying human bitter taste modulators

Country Status (10)

Country Link
US (3) US7407765B2 (enExample)
EP (1) EP1851548A4 (enExample)
JP (1) JP2008537473A (enExample)
CN (1) CN101467040A (enExample)
AU (1) AU2006213039A1 (enExample)
CA (1) CA2597085A1 (enExample)
IL (1) IL185109A0 (enExample)
MX (1) MX2007009497A (enExample)
NO (1) NO20074143L (enExample)
WO (1) WO2006086150A2 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007002026A2 (en) * 2005-06-22 2007-01-04 Senomyx, Inc. Identification of human t2r recepors that are activated by bitter molecules in coffee (chlorogenic lactones) and related assays for identifying human bitter taste modulators
EP1975612A1 (en) 2007-03-29 2008-10-01 Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke-Stiftung des öffentlichen Rechts- Vertreten durch den Stiftungsvorstand Agonists of bitter taste receptors and uses thereof
CA2713885A1 (en) * 2008-02-01 2009-08-20 Chromocell Corporation Novel cell lines and methods
EP2329263A1 (en) * 2008-08-07 2011-06-08 Givaudan SA Methods to identify modulators of the interaction between dextromethorphan and the bitter taste receptor tas2r46
US8557530B2 (en) 2008-08-29 2013-10-15 Givaudan Sa Use of a TAS2R7 nucleic acid sequence to identify modulators
WO2010026003A1 (en) * 2008-09-05 2010-03-11 Unilever Plc Flavan-3-ol containing foodstuffs
WO2012021291A2 (en) * 2010-08-09 2012-02-16 University Of Maryland, Baltimore Methods of treating obstructive lung diseases using bitter tastants
WO2013022948A1 (en) 2011-08-08 2013-02-14 The Coca-Cola Company Cell lines comprising endogenous taste receptors and their uses
ES2797547T3 (es) 2013-03-15 2020-12-02 Applied Food Biotech Inc Receptores del sabor amargo felino y métodos.
US9169311B2 (en) 2013-03-15 2015-10-27 Applied Food Biotechnology, Inc. Feline bitter taste receptors and methods
ES2802376T3 (es) 2014-02-12 2021-01-19 Firmenich Incorporated Procedimiento mejorado para la síntesis de 1-bencil-3-(1-(isoxazol-4-ilmetil)-1h-pirazol-4-il)imidazolidin-2,4-dionas sustituidas
DE102016009766A1 (de) * 2016-08-11 2018-02-15 Julius-Maximilians-Universität Würzburg Herstellung von Bitterstoffderivaten
BR112023021573A2 (pt) * 2021-05-07 2023-12-19 Firmenich Incorporated Células expressando receptores de sabor amargo e usos das mesmas
CN113230256A (zh) * 2021-06-08 2021-08-10 广州医科大学附属中医医院 士的宁在制备肝细胞代谢药物中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001018050A2 (en) * 1999-09-10 2001-03-15 The Regents Of The University Of California T2r taste receptor family
AU2001251258B2 (en) * 2000-04-07 2008-06-05 Senomyx, Inc. T2r taste receptors and genes encoding same
EP1502112A4 (en) * 2001-07-10 2008-07-23 Senomyx Inc USE OF SPECIFIC T2R TASTE RECIPES TO IDENTIFY CONNECTIONS WHICH BLOCK A BITTER TASTE
WO2004069191A2 (en) * 2003-02-03 2004-08-19 Senomyx Inc. Identification of t1r and t2r modulators

Also Published As

Publication number Publication date
WO2006086150A2 (en) 2006-08-17
US20090087866A1 (en) 2009-04-02
MX2007009497A (es) 2008-01-18
US7915003B2 (en) 2011-03-29
CN101467040A (zh) 2009-06-24
EP1851548A2 (en) 2007-11-07
WO2006086150A3 (en) 2009-02-26
US20060199227A1 (en) 2006-09-07
CA2597085A1 (en) 2006-08-17
JP2008537473A (ja) 2008-09-18
US7407765B2 (en) 2008-08-05
EP1851548A4 (en) 2010-04-28
US20110281749A1 (en) 2011-11-17
US8273542B2 (en) 2012-09-25
AU2006213039A1 (en) 2006-08-17
NO20074143L (no) 2007-11-05

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