AU2006213039A1 - Phuman T2R receptors for acetaminophen, ranitidine, strychnine and denatonium and related assays for identifying human bitter taste modulators - Google Patents
Phuman T2R receptors for acetaminophen, ranitidine, strychnine and denatonium and related assays for identifying human bitter taste modulators Download PDFInfo
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
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- G—PHYSICS
- G01—MEASURING; TESTING
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
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- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
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- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
Landscapes
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- Peptides Or Proteins (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| US60/650,555 | 2005-02-08 | ||
| PCT/US2006/002509 WO2006086150A2 (en) | 2005-02-08 | 2006-01-06 | Phuman t2r receptors for acetaminophen, ranitidine, strychnine and denatonium and related assays for identifying human bitter taste modulators |
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| WO2007002026A2 (en) * | 2005-06-22 | 2007-01-04 | Senomyx, Inc. | Identification of human t2r recepors that are activated by bitter molecules in coffee (chlorogenic lactones) and related assays for identifying human bitter taste modulators |
| EP1975612A1 (en) | 2007-03-29 | 2008-10-01 | Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke-Stiftung des öffentlichen Rechts- Vertreten durch den Stiftungsvorstand | Agonists of bitter taste receptors and uses thereof |
| CA2713885A1 (en) * | 2008-02-01 | 2009-08-20 | Chromocell Corporation | Novel cell lines and methods |
| EP2329263A1 (en) * | 2008-08-07 | 2011-06-08 | Givaudan SA | Methods to identify modulators of the interaction between dextromethorphan and the bitter taste receptor tas2r46 |
| US8557530B2 (en) | 2008-08-29 | 2013-10-15 | Givaudan Sa | Use of a TAS2R7 nucleic acid sequence to identify modulators |
| WO2010026003A1 (en) * | 2008-09-05 | 2010-03-11 | Unilever Plc | Flavan-3-ol containing foodstuffs |
| WO2012021291A2 (en) * | 2010-08-09 | 2012-02-16 | University Of Maryland, Baltimore | Methods of treating obstructive lung diseases using bitter tastants |
| WO2013022948A1 (en) | 2011-08-08 | 2013-02-14 | The Coca-Cola Company | Cell lines comprising endogenous taste receptors and their uses |
| ES2797547T3 (es) | 2013-03-15 | 2020-12-02 | Applied Food Biotech Inc | Receptores del sabor amargo felino y métodos. |
| US9169311B2 (en) | 2013-03-15 | 2015-10-27 | Applied Food Biotechnology, Inc. | Feline bitter taste receptors and methods |
| ES2802376T3 (es) | 2014-02-12 | 2021-01-19 | Firmenich Incorporated | Procedimiento mejorado para la síntesis de 1-bencil-3-(1-(isoxazol-4-ilmetil)-1h-pirazol-4-il)imidazolidin-2,4-dionas sustituidas |
| DE102016009766A1 (de) * | 2016-08-11 | 2018-02-15 | Julius-Maximilians-Universität Würzburg | Herstellung von Bitterstoffderivaten |
| BR112023021573A2 (pt) * | 2021-05-07 | 2023-12-19 | Firmenich Incorporated | Células expressando receptores de sabor amargo e usos das mesmas |
| CN113230256A (zh) * | 2021-06-08 | 2021-08-10 | 广州医科大学附属中医医院 | 士的宁在制备肝细胞代谢药物中的应用 |
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| WO2001018050A2 (en) * | 1999-09-10 | 2001-03-15 | The Regents Of The University Of California | T2r taste receptor family |
| AU2001251258B2 (en) * | 2000-04-07 | 2008-06-05 | Senomyx, Inc. | T2r taste receptors and genes encoding same |
| EP1502112A4 (en) * | 2001-07-10 | 2008-07-23 | Senomyx Inc | USE OF SPECIFIC T2R TASTE RECIPES TO IDENTIFY CONNECTIONS WHICH BLOCK A BITTER TASTE |
| WO2004069191A2 (en) * | 2003-02-03 | 2004-08-19 | Senomyx Inc. | Identification of t1r and t2r modulators |
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| US20090087866A1 (en) | 2009-04-02 |
| MX2007009497A (es) | 2008-01-18 |
| US7915003B2 (en) | 2011-03-29 |
| CN101467040A (zh) | 2009-06-24 |
| EP1851548A2 (en) | 2007-11-07 |
| WO2006086150A3 (en) | 2009-02-26 |
| IL185109A0 (en) | 2007-12-03 |
| US20060199227A1 (en) | 2006-09-07 |
| CA2597085A1 (en) | 2006-08-17 |
| JP2008537473A (ja) | 2008-09-18 |
| US7407765B2 (en) | 2008-08-05 |
| EP1851548A4 (en) | 2010-04-28 |
| US20110281749A1 (en) | 2011-11-17 |
| US8273542B2 (en) | 2012-09-25 |
| NO20074143L (no) | 2007-11-05 |
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