IL185106A0 - Stable micronized candesartan cilexetil and methods for preparing thereof - Google Patents

Stable micronized candesartan cilexetil and methods for preparing thereof

Info

Publication number
IL185106A0
IL185106A0 IL185106A IL18510607A IL185106A0 IL 185106 A0 IL185106 A0 IL 185106A0 IL 185106 A IL185106 A IL 185106A IL 18510607 A IL18510607 A IL 18510607A IL 185106 A0 IL185106 A0 IL 185106A0
Authority
IL
Israel
Prior art keywords
preparing
methods
candesartan cilexetil
stable micronized
micronized candesartan
Prior art date
Application number
IL185106A
Other languages
English (en)
Original Assignee
Teva Pharma
Pesachovich Michael
Kurgan Ziv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37101528&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL185106(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Teva Pharma, Pesachovich Michael, Kurgan Ziv filed Critical Teva Pharma
Publication of IL185106A0 publication Critical patent/IL185106A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
IL185106A 2005-05-10 2007-08-07 Stable micronized candesartan cilexetil and methods for preparing thereof IL185106A0 (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US67995205P 2005-05-10 2005-05-10
US68011505P 2005-05-11 2005-05-11
US68445505P 2005-05-24 2005-05-24
US70741705P 2005-08-10 2005-08-10
US70995405P 2005-08-19 2005-08-19
US71699505P 2005-09-13 2005-09-13
US72238805P 2005-09-29 2005-09-29
PCT/US2006/018265 WO2006122254A2 (en) 2005-05-10 2006-05-10 Stable micronized candesartan cilexetil and methods for preparing thereof

Publications (1)

Publication Number Publication Date
IL185106A0 true IL185106A0 (en) 2007-12-03

Family

ID=37101528

Family Applications (1)

Application Number Title Priority Date Filing Date
IL185106A IL185106A0 (en) 2005-05-10 2007-08-07 Stable micronized candesartan cilexetil and methods for preparing thereof

Country Status (10)

Country Link
US (1) US20070082055A1 (enExample)
EP (2) EP2210888B1 (enExample)
JP (2) JP2008505935A (enExample)
KR (1) KR100978592B1 (enExample)
CA (1) CA2599415C (enExample)
DE (1) DE202006020979U1 (enExample)
ES (1) ES2429941T3 (enExample)
IL (1) IL185106A0 (enExample)
TW (1) TW200716615A (enExample)
WO (1) WO2006122254A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006122254A2 (en) * 2005-05-10 2006-11-16 Teva Pharmaceutical Industries Ltd. Stable micronized candesartan cilexetil and methods for preparing thereof
JP5595820B2 (ja) * 2010-01-15 2014-09-24 株式会社トクヤマ カンデサルタンシレキセチルの製造方法
WO2011109579A1 (en) 2010-03-04 2011-09-09 Theravance, Inc. Crystalline alkoxyimidazol-1-ylmethyl biphenyl carboxylic acid and methods for preparing thereof
WO2013041944A1 (en) 2011-09-19 2013-03-28 Ranbaxy Laboratories Limited Process for the preparation of micronized candesartan cilexetil
JP5930686B2 (ja) * 2011-12-07 2016-06-08 株式会社トクヤマ 溶解性および安定性の向上した難溶性医薬品原体及びその製造方法
JP6007096B2 (ja) * 2011-12-28 2016-10-12 エルメッド エーザイ株式会社 安定化カンデサルタンシレキセチル含有物の製造方法
MX2014013320A (es) 2012-05-07 2015-08-10 Bayer Pharma AG Procedimiento de fabricacion de una forma de dosificacion farmaceutica que comprende nifedipina y candesartan cilexetilo.
EP2952187A4 (en) 2013-01-30 2016-08-17 Sawai Seiyaku Kk PHARMACEUTICAL COMPOSITION WITH CANDESARTAN CILEXETIL
JP2016106139A (ja) * 2016-03-07 2016-06-16 株式会社トクヤマ 溶解性および安定性の向上した難溶性医薬品原体及びその製造方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5196444A (en) * 1990-04-27 1993-03-23 Takeda Chemical Industries, Ltd. 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof
US6004989A (en) * 1990-04-27 1999-12-21 Takeda Chemical Industries, Ltd. Benzimidazole derivatives, their production and use
US5703110A (en) * 1990-04-27 1997-12-30 Takeda Chemical Industries, Ltd. Benzimidazole derivatives, their production and use
DE4023369A1 (de) * 1990-07-23 1992-01-30 Thomae Gmbh Dr K Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
US5145684A (en) * 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
TW284688B (enExample) * 1991-11-20 1996-09-01 Takeda Pharm Industry Co Ltd
US5721263A (en) * 1993-06-07 1998-02-24 Takeda Chemical Industries, Ltd. Pharmaceutical composition for angiotensin II-mediated diseases
PT668272E (pt) * 1994-01-28 2000-10-31 Takeda Chemical Industries Ltd Processo para a producao de compostos de tetrazolilo
JP2730501B2 (ja) 1994-01-28 1998-03-25 武田薬品工業株式会社 テトラゾリル化合物の製造法
JP3003030B2 (ja) * 1997-05-26 2000-01-24 武田薬品工業株式会社 アミノベンゼン化合物の製造法
SE9901667D0 (sv) * 1999-05-07 1999-05-07 Astra Ab Method and device for forming particles
CN1204125C (zh) * 2000-12-27 2005-06-01 中国科学院上海药物研究所 坎地沙坦酯的合成新路线
CA2453890A1 (en) * 2001-08-03 2003-02-20 Takeda Chemical Industries, Ltd. Crystal and process for producing the same
CA2562597A1 (en) * 2004-05-05 2005-11-24 Marina Yu Etinger Preparation of candesartan cilexetil in high purity
WO2005123720A1 (en) * 2004-06-18 2005-12-29 Ranbaxy Laboratories Limited Fine particles of the angiotensin ii antagonist candesartan cilexetil and process for production thereof
AU2006204083A1 (en) 2005-01-06 2006-07-13 Elan Pharma International Ltd. Nanoparticulate candesartan formulations
WO2006122254A2 (en) * 2005-05-10 2006-11-16 Teva Pharmaceutical Industries Ltd. Stable micronized candesartan cilexetil and methods for preparing thereof

Also Published As

Publication number Publication date
TW200716615A (en) 2007-05-01
US20070082055A1 (en) 2007-04-12
CA2599415A1 (en) 2006-11-16
JP2008505935A (ja) 2008-02-28
KR100978592B1 (ko) 2010-08-27
WO2006122254A2 (en) 2006-11-16
EP1763525A2 (en) 2007-03-21
EP2210888B1 (en) 2013-04-24
WO2006122254A3 (en) 2007-01-25
ES2429941T3 (es) 2013-11-18
DE202006020979U1 (de) 2011-08-05
EP2210888A3 (en) 2010-09-15
KR20070062500A (ko) 2007-06-15
JP2010270148A (ja) 2010-12-02
CA2599415C (en) 2011-07-19
EP2210888A2 (en) 2010-07-28

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