IL180896A - Method @ Separation @ between @ tissue @ cancer and cancer using @ magnetic resonance imaging - Google Patents

Method @ Separation @ between @ tissue @ cancer and cancer using @ magnetic resonance imaging

Info

Publication number
IL180896A
IL180896A IL180896A IL18089607A IL180896A IL 180896 A IL180896 A IL 180896A IL 180896 A IL180896 A IL 180896A IL 18089607 A IL18089607 A IL 18089607A IL 180896 A IL180896 A IL 180896A
Authority
IL
Israel
Prior art keywords
imaging
discrimination
healthy
tumour tissue
tumour
Prior art date
Application number
IL180896A
Other languages
English (en)
Hebrew (he)
Other versions
IL180896A0 (en
Original Assignee
Ge Healthcare As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare As filed Critical Ge Healthcare As
Publication of IL180896A0 publication Critical patent/IL180896A0/en
Publication of IL180896A publication Critical patent/IL180896A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A61B5/055Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48NMR imaging systems
    • G01R33/483NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy
    • G01R33/485NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy based on chemical shift information [CSI] or spectroscopic imaging, e.g. to acquire the spatial distributions of metabolites
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0404Lipids, e.g. triglycerides; Polycationic carriers
    • A61K51/0406Amines, polyamines, e.g. spermine, spermidine, amino acids, (bis)guanidines
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48NMR imaging systems
    • G01R33/54Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Signal Processing (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Lasers (AREA)
IL180896A 2004-07-30 2007-01-23 Method @ Separation @ between @ tissue @ cancer and cancer using @ magnetic resonance imaging IL180896A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO20043226 2004-07-30
PCT/NO2005/000282 WO2006011810A2 (en) 2004-07-30 2005-07-28 Mr imaging method for the discrimination between healthy and tumour tissue

Publications (2)

Publication Number Publication Date
IL180896A0 IL180896A0 (en) 2007-07-04
IL180896A true IL180896A (en) 2013-07-31

Family

ID=35501891

Family Applications (1)

Application Number Title Priority Date Filing Date
IL180896A IL180896A (en) 2004-07-30 2007-01-23 Method @ Separation @ between @ tissue @ cancer and cancer using @ magnetic resonance imaging

Country Status (15)

Country Link
EP (1) EP1784227B1 (https=)
JP (1) JP5362987B2 (https=)
KR (1) KR101126952B1 (https=)
CN (2) CN102565735B (https=)
AT (1) ATE527552T1 (https=)
AU (1) AU2005267669B2 (https=)
BR (1) BRPI0513896A (https=)
CA (1) CA2576202A1 (https=)
ES (1) ES2372058T3 (https=)
IL (1) IL180896A (https=)
MX (1) MX2007001033A (https=)
PL (1) PL1784227T3 (https=)
RU (1) RU2369406C2 (https=)
WO (1) WO2006011810A2 (https=)
ZA (1) ZA200701280B (https=)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5475995B2 (ja) 2005-12-01 2014-04-16 ジーイー・ヘルスケア・アクスイェ・セルスカプ 動的核分極(dnp)法
US20100233096A1 (en) * 2006-03-29 2010-09-16 Lerche Mathilde H Method to produce hyperpolarised carboxylates and sulphonates
US7202665B1 (en) 2006-04-19 2007-04-10 Wisconsin Alumni Research Foundation Magnetic resonance spectroscopy of species with multiple peaks
CN101506679B (zh) * 2006-08-18 2013-03-06 通用电气医疗集团股份有限公司 细胞死亡的13c-mr成像或波谱分析
EP2051739A2 (en) * 2006-08-18 2009-04-29 GE Healthcare AS Imaging medium comprising lactate and hyperpolarised 13c-pyruvate
KR20140144312A (ko) 2006-08-30 2014-12-18 지이 헬스케어 에이에스 동적 핵 분극화 방법 및 이러한 방법에서 사용되는 화합물 및 조성물
US20100087679A1 (en) * 2006-10-17 2010-04-08 Torgrim Engell Method for the production of alpha-deto acids and esters thereof
WO2008063078A1 (en) * 2006-11-21 2008-05-29 Ge Healthcare As Method for managing patients with cancers
US8812076B2 (en) * 2006-11-21 2014-08-19 General Electric Company Proton decoupled hyperpolarized magnetic resonance imaging
WO2008086534A1 (en) 2007-01-11 2008-07-17 Huntington Medical Research Institutes Imaging agents and methods of use thereof
US7470813B2 (en) 2007-03-30 2008-12-30 Ge Healthcare Limited Method for the production of pyruvic acid
US20080242974A1 (en) * 2007-04-02 2008-10-02 Urbahn John A Method and apparatus to hyperpolarize materials for enhanced mr techniques
US7741844B2 (en) * 2007-05-07 2010-06-22 General Electric Company Method and system for magnetic resonance imaging using labeled contrast agents
CN105054933A (zh) * 2007-05-17 2015-11-18 通用电气公司 使用包含超极化13c-丙酮酸盐的成像介质使肿瘤分级的mr方法
CN101970014A (zh) * 2007-07-26 2011-02-09 通用电气医疗集团英国有限公司 包含超极化的13c-乳酸盐的成像介质及其用途
US20110033387A1 (en) * 2007-09-07 2011-02-10 Ge Healthcare Limited Method of determination of pdh activity and imaging media for use in said method
JP5448397B2 (ja) * 2007-09-07 2014-03-19 キヤノン株式会社 基質プローブ、多重核磁気共鳴法による酵素活性の検出方法および酵素活性のイメージング方法
EP2072061A1 (en) 2007-12-19 2009-06-24 GE Healthcare Limited Composition and method for generating a metabolic profile using 13C-MR detection
US20110038804A1 (en) * 2007-12-21 2011-02-17 Anna Gisselsson Mr imaging agent, imaging medium and methods of imaging wherein such an imaging medium is used
WO2009098192A1 (en) * 2008-02-04 2009-08-13 Ge Healthcare Limited Mr imaging agent or medium compressing hzperpolarised 13c alanine and methods of imaging wherein such an imaging medium is used
WO2009129265A1 (en) 2008-04-14 2009-10-22 Huntington Medical Research Institutes Methods and apparatus for pasadena hyperpolarization
US8763410B2 (en) * 2008-04-21 2014-07-01 General Electric Company Method and apparatus for the dissolution and filtration of a hyperpolarized agent with a neutral dissolution media
US20110038802A1 (en) * 2008-05-02 2011-02-17 Zhong-Min Hu Method of determining alanine transaminase (alt) activity by 13c-mr detection using hyperpolarised 13c-pyruvate
AU2010230330B2 (en) * 2009-04-02 2015-06-25 Ge Healthcare Limited Use of a magnetic resonance imaging medium comprising hyperpolarized 13C pyruvate for the detection of inflammation or infection
US8968703B2 (en) 2009-09-10 2015-03-03 Ge Healthcare Limited 13C-MR detection using hyperpolarised 13C-fructose
US9069098B2 (en) * 2011-09-09 2015-06-30 Schlumberger Technology Corporation Three or more multiple figure-eight coils for NMR well-logging measurements with azimuthal directional sensitivity
WO2014003643A1 (en) 2012-06-29 2014-01-03 Cr Development Ab Quantification of the relative amount of water in the tissue microcapillary network
EP2972441B1 (en) 2013-03-14 2016-11-30 Ecole Polytechnique Fédérale de Lausanne (EPFL) Method for the generation of radicals for dynamic nuclear polarization and uses thereof for nmr, mrs and mri
US9874622B2 (en) 2013-09-27 2018-01-23 General Electric Company Hyperpolarized media transport vessel
DK3058375T3 (en) * 2013-10-15 2019-04-08 Univ Muenchen Tech pH Biosensors based on compounds made of pyruvic acid for magnetic resonance imaging and spectroscopy and their applications
EP2863229A1 (en) * 2013-10-15 2015-04-22 Technische Universität München pH-biosensors based on compounds with pH-sensitive enolic groups for magnetic resonance imaging and spectroscopy and their uses
KR101516634B1 (ko) * 2014-07-09 2015-05-06 연세대학교 산학협력단 13c-자기공명분광영상을 이용한 암 환자의 치료 예후를 예측하는 방법
WO2017147418A1 (en) 2016-02-24 2017-08-31 Ohio State Innovation Foundation Methods and devices for contrast agent magnetic resonance imaging
CN109477872A (zh) * 2016-03-10 2019-03-15 纪念斯隆凯特琳癌症中心 超极化微核磁共振系统和方法
RU2634783C1 (ru) * 2016-07-05 2017-11-03 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр онкологии имени Н.Н. Петрова" Министерства здравоохранения Российской Федерации Способ дифференциальной диагностики образований молочной железы и мягких тканей
KR101939454B1 (ko) * 2017-03-21 2019-01-16 전남대학교산학협력단 생체 내 과분극화 c13 피루베이트 자기공명분광법을 이용하여 새로운 정량적 생체지표를 통한 비알코올성 지방간질환 진단 방법
KR102441674B1 (ko) * 2017-11-21 2022-09-08 솔벡스 리미티드 라이어빌리티 컴퍼니 중수소화된 2-아미노-2-메틸프로피온산 및/또는 2-(n-메틸아미노)-2-메틸프로피온산을 포함하는, 종양성 질환의 자기공명진단을 위한 제제, 및 상기 제제를 이용한 진단방법
RU2741212C1 (ru) * 2020-03-12 2021-01-22 Государственное автономное учреждение здравоохранения «Республиканский клинический онкологический диспансер Министерства здравоохранения Республики Татарстан» (ГАУЗ «РКОД МЗ РТ») Способ диагностики злокачественных очаговых образований периферической зоны предстательной железы
RU2749126C1 (ru) * 2020-05-06 2021-06-04 Государственное автономное учреждение здравоохранения «Республиканский клинический онкологический диспансер Министерства здравоохранения Республики Татарстан» (ГАУЗ «РКОД МЗ РТ») Способ дифференциальной диагностики очаговых образований предстательной железы
EP4140505A1 (en) * 2021-08-26 2023-03-01 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Purified signal-enhanced contrast agents for magnetic resonance imaging

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01265950A (ja) * 1988-04-15 1989-10-24 Toshiba Corp スペクトロスコピックイメージング装置
DE3920433A1 (de) * 1989-06-22 1991-01-03 Philips Patentverwaltung Kernresonanzabbildungsverfahren
US5323780A (en) * 1992-08-07 1994-06-28 University Of Florida Research Foundation, Inc. Artifact-free imaging contrast agent
US5671741A (en) * 1995-08-04 1997-09-30 The Regents Of The University Of California Magnetic resonance imaging technique for tissue characterization
CN1224502A (zh) * 1996-03-29 1999-07-28 劳伦斯·伯克利国家实验室 利用超极化惰性气体对于核磁共振和磁共振成象质量的提高
FI982069A7 (fi) * 1996-03-29 1998-11-10 Lawrence Berkeley Nat Laboratory NMR:n ja MRI:n tehostaminen hyperpolaroitujen jalokaasujen läsnä olles sa
US6278893B1 (en) * 1998-01-05 2001-08-21 Nycomed Imaging As Method of magnetic resonance imaging of a sample with ex vivo polarization of an MR imaging agent
DE102004011874B4 (de) * 2004-03-11 2006-04-20 Universitätsklinikum Freiburg Verfahren zur Messung der Magnetresonanz (NMR) mittels Continuously Refocused Multiecho Spectroscopic Imaging

Also Published As

Publication number Publication date
ATE527552T1 (de) 2011-10-15
HK1107003A1 (en) 2008-03-28
WO2006011810A2 (en) 2006-02-02
PL1784227T3 (pl) 2012-03-30
CN102565735A (zh) 2012-07-11
EP1784227A2 (en) 2007-05-16
RU2369406C2 (ru) 2009-10-10
ES2372058T3 (es) 2012-01-13
MX2007001033A (es) 2007-07-25
EP1784227B1 (en) 2011-10-05
RU2007102845A (ru) 2008-09-10
AU2005267669B2 (en) 2011-02-24
CN101031811A (zh) 2007-09-05
KR101126952B1 (ko) 2012-03-20
CA2576202A1 (en) 2006-02-02
JP5362987B2 (ja) 2013-12-11
AU2005267669A1 (en) 2006-02-02
BRPI0513896A (pt) 2008-05-20
CN102565735B (zh) 2016-02-10
IL180896A0 (en) 2007-07-04
WO2006011810A3 (en) 2006-04-13
JP2008508023A (ja) 2008-03-21
ZA200701280B (en) 2008-09-25
KR20070061806A (ko) 2007-06-14

Similar Documents

Publication Publication Date Title
ZA200701280B (en) MR imaging method for the discrimination between healthy and tumour tissue
WO2002080754A3 (en) Methods for using annexin for detecting cell death in vivo and treating associated conditions
PT1472541E (pt) Agentes de imagiologia e métodos de imagiologia de naaladase de psma
WO2006054903A3 (en) Method of cardiac imaging with the use of hyperpolarized 13 c-pyruvate
MX2007001035A (es) Metodo para producir una composicion, la composicion y su uso.
EP1608282A4 (en) METHODS OF DIAGNOSING SKIN LESIONS
WO2004066805A3 (en) In vivo device for improving diastolic ventricular function
EP2468776A3 (en) Anti-Robo4 antibodies and uses therefor
WO2007109236A8 (en) Microrna fingerprints during human megakaryocytopoiesis
IL185501A0 (en) Novel diagnostic markers, especially for in vivo imaging, and assays and methods of use thereof
IL177346A0 (en) Compositions and methods for characterizing, regulating, diagnosing, and treating cancer
MX2007007380A (es) Derivados de estilbeno y su uso para estudios de union y por imagenes de placas amiloides.
DE50204163D1 (de) Mammographie-Zusatz für MR-Elastographie
TW200510398A (en) Novel compounds
IL153183A0 (en) Agents for imaging and diagnostic methods using them
WO2007082048A3 (en) Ex vivo hyperpolarization of imaging agents
WO2004087734A3 (en) Stq-peptides
WO2007070466A3 (en) In situ hyperpolarization of imaging agents
IL175004A0 (en) Quick test for the diagnosis of alzheimer's disease
DE60030270D1 (de) Fettsaure analoge zur diagnose von kranzarterie erkrankungen
WO2006088940A3 (en) Neoplasia screening compositions and methods of use
EP1465911A4 (en) COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF DIABETES, INSULIN RESISTANCE AND DYSLIPIDEMIA
WO2007012937A3 (en) Method for diagnosis of glioma distinguishing between progressive and denovo types
WO2005089414A3 (en) Neoplasia diagnostic compositions and methods of use
MY156251A (en) Glucuronidated acetaminophen as a marker of hepatic disorders

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed