IL180894A - 1-alpha-halo-2,2-difluoro-2-deoxy-d-ribofuranose derivatives and processes for the preparation thereof - Google Patents
1-alpha-halo-2,2-difluoro-2-deoxy-d-ribofuranose derivatives and processes for the preparation thereofInfo
- Publication number
- IL180894A IL180894A IL180894A IL18089407A IL180894A IL 180894 A IL180894 A IL 180894A IL 180894 A IL180894 A IL 180894A IL 18089407 A IL18089407 A IL 18089407A IL 180894 A IL180894 A IL 180894A
- Authority
- IL
- Israel
- Prior art keywords
- formula
- compound
- halide
- derivative
- mixture
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/08—Deoxysugars; Unsaturated sugars; Osones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20040059623 | 2004-07-29 | ||
KR1020050041278A KR100699099B1 (ko) | 2004-07-29 | 2005-05-17 | 1-α-할로-2,2-다이플루오로-2-데옥시-D-라이보퓨라노스유도체 및 이의 제조방법 |
PCT/KR2005/001922 WO2006011713A1 (en) | 2004-07-29 | 2005-06-21 | 1-α-HALO-2,2-DIFLUORO-2-DEOXY-D-RIBOFURANOSE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF |
Publications (2)
Publication Number | Publication Date |
---|---|
IL180894A0 IL180894A0 (en) | 2007-07-04 |
IL180894A true IL180894A (en) | 2011-09-27 |
Family
ID=37149831
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL180894A IL180894A (en) | 2004-07-29 | 2007-01-23 | 1-alpha-halo-2,2-difluoro-2-deoxy-d-ribofuranose derivatives and processes for the preparation thereof |
Country Status (7)
Country | Link |
---|---|
JP (1) | JP4691101B2 (ko) |
KR (1) | KR100699099B1 (ko) |
CN (1) | CN1989148B (ko) |
HK (1) | HK1100946A1 (ko) |
IL (1) | IL180894A (ko) |
MX (1) | MX2007000959A (ko) |
RU (1) | RU2346948C2 (ko) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5349342B2 (ja) | 2007-03-23 | 2013-11-20 | ドンウ シンテック カンパニー リミテッド | 2’−デオキシ−2’,2’−ジフルオロシチジンの製造方法 |
KR100858842B1 (ko) * | 2007-03-23 | 2008-09-22 | 동우신테크 주식회사 | 키랄아민을 이용한 광학활성 옥소라이보스유도체의제조방법 |
CN101628927B (zh) * | 2009-08-07 | 2012-10-10 | 卡硼瑞(北京)科技有限公司 | 以1,3,5-三-O-苯甲酰基-α-D-呋喃核糖为原料立体选择性制备β-二氟胞苷盐酸盐的方法 |
CN103897008A (zh) * | 2012-12-28 | 2014-07-02 | 石药集团中奇制药技术(石家庄)有限公司 | 一种地西他滨及其中间体的制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2039403A1 (en) * | 1990-04-04 | 1991-10-05 | Gerald Saischek | Process for the manufacture of 2-deoxy-d-threo-pentofuranosides, intermediates for their manufacture and their use |
ATE153669T1 (de) * | 1992-06-22 | 1997-06-15 | Lilly Co Eli | Verfahren zur herstellung von mit alpha-anomeren angereicherten 1-halogen-2-deoxy-2,2-difluor-d- ribofuranosyl-derivaten |
AU720451B2 (en) * | 1997-01-24 | 2000-06-01 | Conpharma As | Gemcitabine derivatives |
JP2003055364A (ja) * | 2001-06-07 | 2003-02-26 | Mitsui Chemicals Inc | 2,3−ジデオキシ−2,3−デヒドロペントフラノース誘導体に関する新規製造法 |
-
2005
- 2005-05-17 KR KR1020050041278A patent/KR100699099B1/ko active IP Right Grant
- 2005-06-21 MX MX2007000959A patent/MX2007000959A/es active IP Right Grant
- 2005-06-21 JP JP2007523465A patent/JP4691101B2/ja not_active Expired - Fee Related
- 2005-06-21 CN CN2005800251579A patent/CN1989148B/zh not_active Expired - Fee Related
- 2005-06-21 RU RU2007107607/04A patent/RU2346948C2/ru not_active IP Right Cessation
-
2007
- 2007-01-23 IL IL180894A patent/IL180894A/en not_active IP Right Cessation
- 2007-08-17 HK HK07108984.4A patent/HK1100946A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
MX2007000959A (es) | 2007-04-16 |
HK1100946A1 (en) | 2007-10-05 |
JP4691101B2 (ja) | 2011-06-01 |
RU2007107607A (ru) | 2008-09-10 |
JP2008508261A (ja) | 2008-03-21 |
KR20060047970A (ko) | 2006-05-18 |
RU2346948C2 (ru) | 2009-02-20 |
KR100699099B1 (ko) | 2007-03-22 |
IL180894A0 (en) | 2007-07-04 |
CN1989148B (zh) | 2010-05-12 |
CN1989148A (zh) | 2007-06-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |