IL171974A0 - Tetrahydrocarbazole derivatives and their pharmaceutical use - Google Patents

Tetrahydrocarbazole derivatives and their pharmaceutical use

Info

Publication number
IL171974A0
IL171974A0 IL171974A IL17197405A IL171974A0 IL 171974 A0 IL171974 A0 IL 171974A0 IL 171974 A IL171974 A IL 171974A IL 17197405 A IL17197405 A IL 17197405A IL 171974 A0 IL171974 A0 IL 171974A0
Authority
IL
Israel
Prior art keywords
pharmaceutical use
tetrahydrocarbazole derivatives
tetrahydrocarbazole
derivatives
compounds
Prior art date
Application number
IL171974A
Other languages
English (en)
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of IL171974A0 publication Critical patent/IL171974A0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/82Carbazoles; Hydrogenated carbazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/82Carbazoles; Hydrogenated carbazoles
    • C07D209/88Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
IL171974A 2003-06-10 2005-11-15 Tetrahydrocarbazole derivatives and their pharmaceutical use IL171974A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US47725103P 2003-06-10 2003-06-10
US49782303P 2003-08-26 2003-08-26
PCT/US2004/017660 WO2004110999A1 (en) 2003-06-10 2004-06-07 Tetrahydrocarbazole derivatives and their pharmaceutical use

Publications (1)

Publication Number Publication Date
IL171974A0 true IL171974A0 (en) 2006-04-10

Family

ID=33555453

Family Applications (1)

Application Number Title Priority Date Filing Date
IL171974A IL171974A0 (en) 2003-06-10 2005-11-15 Tetrahydrocarbazole derivatives and their pharmaceutical use

Country Status (16)

Country Link
US (1) US7351733B2 (https=)
EP (1) EP1654228B1 (https=)
JP (1) JP2007501284A (https=)
KR (1) KR20060017545A (https=)
AT (1) ATE411981T1 (https=)
AU (1) AU2004247676A1 (https=)
BR (1) BRPI0411085A (https=)
CA (1) CA2528321A1 (https=)
CO (1) CO5660287A2 (https=)
DE (1) DE602004017326D1 (https=)
ES (1) ES2314446T3 (https=)
IL (1) IL171974A0 (https=)
MA (1) MA27880A1 (https=)
NO (1) NO20055741L (https=)
RU (1) RU2318810C2 (https=)
WO (1) WO2004110999A1 (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7622494B2 (en) 2003-08-26 2009-11-24 Smithkline Beecham Corporation Chemical compounds
MXPA06010543A (es) 2004-03-15 2007-03-26 Ptc Therapeutics Inc Derivados de carbolina utiles en la inhibicion de la angiogenesis.
US7767689B2 (en) 2004-03-15 2010-08-03 Ptc Therapeutics, Inc. Carboline derivatives useful in the treatment of cancer
US8076352B2 (en) 2004-03-15 2011-12-13 Ptc Therapeutics, Inc. Administration of carboline derivatives useful in the treatment of cancer and other diseases
US8076353B2 (en) 2004-03-15 2011-12-13 Ptc Therapeutics, Inc. Inhibition of VEGF translation
WO2006012310A2 (en) * 2004-06-25 2006-02-02 Genzyme Corporation Carbazole derivatives for treating polycystic kidney disease
JP2008520675A (ja) * 2004-11-22 2008-06-19 スミスクライン ビーチャム コーポレーション Hcv阻害剤
US8143257B2 (en) * 2004-11-23 2012-03-27 Ptc Therapeutics, Inc. Substituted phenols as active agents inhibiting VEGF production
WO2007002051A1 (en) * 2005-06-22 2007-01-04 Smithkline Beecham Corporation Carboline derivatives and their use as inhibitors of flaviviridae infections
WO2013139929A1 (en) * 2012-03-22 2013-09-26 Ludwig-Maximilians-Universität München Novel means and methods for treating diseases of the central nervous system, metabolic and cardiac diseases and aging
WO2013177241A1 (en) 2012-05-22 2013-11-28 Trustees Of Dartmouth College Method for synthesizing cycloalkanyl(b}indoles, cycloalkanyl(b) benzofurans, cycloalkanyl(b)benzothiophenes, compounds and methods of use
EP2690091A1 (en) 2012-07-25 2014-01-29 Studiengesellschaft Kohle mbH Process for preparing substituted indole derivatives
KR101671484B1 (ko) 2016-07-21 2016-11-01 김정환 오셀타미비르(Oseltamivir)를 포함하는 인유두종 바이러스 치료용 약학적 조성물
US10882821B1 (en) 2017-09-26 2021-01-05 The Board Of Trustees Of The Leland Stanford Junior University Enantiomeric compound for the reduction of the deleterious activity of extended nucleotide repeat containing genes
WO2021183980A1 (en) * 2020-03-13 2021-09-16 Fmc Corporation Substituted pyrimidines and triazines as herbicides
CN113995758B (zh) * 2021-11-04 2023-06-02 中山大学 咔唑-嘧啶衍生物在制备治疗抗肿瘤药物中的应用
KR102907984B1 (ko) 2022-11-22 2026-01-06 이경엽 알칼로이드 함유 인유두종 바이러스 감염의 예방 또는 치료용 조성물
KR102907985B1 (ko) 2022-11-22 2026-01-06 이경엽 인유두종 바이러스 감염에 의한 후두유두종의 예방 또는 치료용 조성물
EP4725481A1 (en) * 2024-10-10 2026-04-15 Leibniz-Institut für Virologie 1,2,3,4-tetrahydrocarbazole derivatives for use in treating an adenoviral infection

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE507797C (de) * 1927-05-14 1930-09-20 I G Farbenindustrie Akt Ges Verfahren zur Herstellung von 1-Aminocarbazol und seinen Derivaten
GB8924392D0 (en) * 1989-10-30 1989-12-20 Bayer Ag Substituted cycloalkano/b/dihydroindole-and-indolesulphonamides
GB9008108D0 (en) * 1990-04-10 1990-06-06 Bayer Ag Cycloalkano(b)dihydroindoles and-indolesulphonamides substituted by heterocycles
US5100891A (en) 1991-01-18 1992-03-31 Hoechst-Roussel Pharmaceuticals Inc. Substituted 1,2,3,4-tetrahydrocyclopent[b]indoles, 1,2,3,3a,4,8a-hexahydrocyclopent[B]indoles and related compounds
CA2106642C (en) * 1992-10-14 2005-08-16 Peter Bod Carbazolone derivatives and process for preparing the same
US6045398A (en) * 1995-07-10 2000-04-04 International Business Machines Corporation Battery accepting unit and battery pack
GB0015904D0 (en) * 2000-06-28 2000-08-23 Hoffmann La Roche Inhibitors of HPV E1 helicase enzyme
NZ533430A (en) * 2001-12-14 2005-12-23 Zentaris Gmbh Tetrahydrocarbozole derivatives as ligands for G-protein coupled receptors (GPCR)
DE10164564B4 (de) * 2001-12-14 2007-05-16 Zentaris Gmbh Tetrahydrocarbazolderivate als Liganden für G-Protein gekoppelte Rezeptoren (GPCR)

Also Published As

Publication number Publication date
US20060161002A1 (en) 2006-07-20
EP1654228A1 (en) 2006-05-10
AU2004247676A1 (en) 2004-12-23
ATE411981T1 (de) 2008-11-15
RU2005138124A (ru) 2006-07-10
NO20055741D0 (no) 2005-12-05
DE602004017326D1 (de) 2008-12-04
US7351733B2 (en) 2008-04-01
CO5660287A2 (es) 2006-07-31
WO2004110999A1 (en) 2004-12-23
NO20055741L (no) 2006-01-06
BRPI0411085A (pt) 2006-07-25
JP2007501284A (ja) 2007-01-25
MA27880A1 (fr) 2006-05-02
ES2314446T3 (es) 2009-03-16
KR20060017545A (ko) 2006-02-23
RU2318810C2 (ru) 2008-03-10
CA2528321A1 (en) 2004-12-23
EP1654228B1 (en) 2008-10-22

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