BRPI0411085A - composto, composição farmacêutica, uso de um composto, e, métodos para o tratamento ou profilaxia de vìrus oncogênicos, e de condições ou distúrbios devidos a infecção por hpv - Google Patents
composto, composição farmacêutica, uso de um composto, e, métodos para o tratamento ou profilaxia de vìrus oncogênicos, e de condições ou distúrbios devidos a infecção por hpvInfo
- Publication number
- BRPI0411085A BRPI0411085A BRPI0411085-4A BRPI0411085A BRPI0411085A BR PI0411085 A BRPI0411085 A BR PI0411085A BR PI0411085 A BRPI0411085 A BR PI0411085A BR PI0411085 A BRPI0411085 A BR PI0411085A
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- treatment
- methods
- prophylaxis
- conditions
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 238000011282 treatment Methods 0.000 title abstract 2
- 208000009608 Papillomavirus Infections Diseases 0.000 title 1
- 241000700605 Viruses Species 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 231100000590 oncogenic Toxicity 0.000 title 1
- 230000002246 oncogenic effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 238000011321 prophylaxis Methods 0.000 title 1
- 241000701806 Human papillomavirus Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47725103P | 2003-06-10 | 2003-06-10 | |
| US49782303P | 2003-08-26 | 2003-08-26 | |
| PCT/US2004/017660 WO2004110999A1 (en) | 2003-06-10 | 2004-06-07 | Tetrahydrocarbazole derivatives and their pharmaceutical use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0411085A true BRPI0411085A (pt) | 2006-07-25 |
Family
ID=33555453
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0411085-4A BRPI0411085A (pt) | 2003-06-10 | 2004-06-07 | composto, composição farmacêutica, uso de um composto, e, métodos para o tratamento ou profilaxia de vìrus oncogênicos, e de condições ou distúrbios devidos a infecção por hpv |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7351733B2 (https=) |
| EP (1) | EP1654228B1 (https=) |
| JP (1) | JP2007501284A (https=) |
| KR (1) | KR20060017545A (https=) |
| AT (1) | ATE411981T1 (https=) |
| AU (1) | AU2004247676A1 (https=) |
| BR (1) | BRPI0411085A (https=) |
| CA (1) | CA2528321A1 (https=) |
| CO (1) | CO5660287A2 (https=) |
| DE (1) | DE602004017326D1 (https=) |
| ES (1) | ES2314446T3 (https=) |
| IL (1) | IL171974A0 (https=) |
| MA (1) | MA27880A1 (https=) |
| NO (1) | NO20055741L (https=) |
| RU (1) | RU2318810C2 (https=) |
| WO (1) | WO2004110999A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7622494B2 (en) | 2003-08-26 | 2009-11-24 | Smithkline Beecham Corporation | Chemical compounds |
| MXPA06010543A (es) | 2004-03-15 | 2007-03-26 | Ptc Therapeutics Inc | Derivados de carbolina utiles en la inhibicion de la angiogenesis. |
| US7767689B2 (en) | 2004-03-15 | 2010-08-03 | Ptc Therapeutics, Inc. | Carboline derivatives useful in the treatment of cancer |
| US8076352B2 (en) | 2004-03-15 | 2011-12-13 | Ptc Therapeutics, Inc. | Administration of carboline derivatives useful in the treatment of cancer and other diseases |
| US8076353B2 (en) | 2004-03-15 | 2011-12-13 | Ptc Therapeutics, Inc. | Inhibition of VEGF translation |
| WO2006012310A2 (en) * | 2004-06-25 | 2006-02-02 | Genzyme Corporation | Carbazole derivatives for treating polycystic kidney disease |
| JP2008520675A (ja) * | 2004-11-22 | 2008-06-19 | スミスクライン ビーチャム コーポレーション | Ｈｃｖ阻害剤 |
| US8143257B2 (en) * | 2004-11-23 | 2012-03-27 | Ptc Therapeutics, Inc. | Substituted phenols as active agents inhibiting VEGF production |
| WO2007002051A1 (en) * | 2005-06-22 | 2007-01-04 | Smithkline Beecham Corporation | Carboline derivatives and their use as inhibitors of flaviviridae infections |
| WO2013139929A1 (en) * | 2012-03-22 | 2013-09-26 | Ludwig-Maximilians-Universität München | Novel means and methods for treating diseases of the central nervous system, metabolic and cardiac diseases and aging |
| WO2013177241A1 (en) | 2012-05-22 | 2013-11-28 | Trustees Of Dartmouth College | Method for synthesizing cycloalkanyl(b}indoles, cycloalkanyl(b) benzofurans, cycloalkanyl(b)benzothiophenes, compounds and methods of use |
| EP2690091A1 (en) | 2012-07-25 | 2014-01-29 | Studiengesellschaft Kohle mbH | Process for preparing substituted indole derivatives |
| KR101671484B1 (ko) | 2016-07-21 | 2016-11-01 | 김정환 | 오셀타미비르(Oseltamivir)를 포함하는 인유두종 바이러스 치료용 약학적 조성물 |
| US10882821B1 (en) | 2017-09-26 | 2021-01-05 | The Board Of Trustees Of The Leland Stanford Junior University | Enantiomeric compound for the reduction of the deleterious activity of extended nucleotide repeat containing genes |
| WO2021183980A1 (en) * | 2020-03-13 | 2021-09-16 | Fmc Corporation | Substituted pyrimidines and triazines as herbicides |
| CN113995758B (zh) * | 2021-11-04 | 2023-06-02 | 中山大学 | 咔唑-嘧啶衍生物在制备治疗抗肿瘤药物中的应用 |
| KR102907984B1 (ko) | 2022-11-22 | 2026-01-06 | 이경엽 | 알칼로이드 함유 인유두종 바이러스 감염의 예방 또는 치료용 조성물 |
| KR102907985B1 (ko) | 2022-11-22 | 2026-01-06 | 이경엽 | 인유두종 바이러스 감염에 의한 후두유두종의 예방 또는 치료용 조성물 |
| EP4725481A1 (en) * | 2024-10-10 | 2026-04-15 | Leibniz-Institut für Virologie | 1,2,3,4-tetrahydrocarbazole derivatives for use in treating an adenoviral infection |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE507797C (de) * | 1927-05-14 | 1930-09-20 | I G Farbenindustrie Akt Ges | Verfahren zur Herstellung von 1-Aminocarbazol und seinen Derivaten |
| GB8924392D0 (en) * | 1989-10-30 | 1989-12-20 | Bayer Ag | Substituted cycloalkano/b/dihydroindole-and-indolesulphonamides |
| GB9008108D0 (en) * | 1990-04-10 | 1990-06-06 | Bayer Ag | Cycloalkano(b)dihydroindoles and-indolesulphonamides substituted by heterocycles |
| US5100891A (en) | 1991-01-18 | 1992-03-31 | Hoechst-Roussel Pharmaceuticals Inc. | Substituted 1,2,3,4-tetrahydrocyclopent[b]indoles, 1,2,3,3a,4,8a-hexahydrocyclopent[B]indoles and related compounds |
| CA2106642C (en) * | 1992-10-14 | 2005-08-16 | Peter Bod | Carbazolone derivatives and process for preparing the same |
| US6045398A (en) * | 1995-07-10 | 2000-04-04 | International Business Machines Corporation | Battery accepting unit and battery pack |
| GB0015904D0 (en) * | 2000-06-28 | 2000-08-23 | Hoffmann La Roche | Inhibitors of HPV E1 helicase enzyme |
| NZ533430A (en) * | 2001-12-14 | 2005-12-23 | Zentaris Gmbh | Tetrahydrocarbozole derivatives as ligands for G-protein coupled receptors (GPCR) |
| DE10164564B4 (de) * | 2001-12-14 | 2007-05-16 | Zentaris Gmbh | Tetrahydrocarbazolderivate als Liganden für G-Protein gekoppelte Rezeptoren (GPCR) |
-
2004
- 2004-06-07 KR KR1020057023781A patent/KR20060017545A/ko not_active Withdrawn
- 2004-06-07 JP JP2006533561A patent/JP2007501284A/ja active Pending
- 2004-06-07 WO PCT/US2004/017660 patent/WO2004110999A1/en not_active Ceased
- 2004-06-07 DE DE602004017326T patent/DE602004017326D1/de not_active Expired - Lifetime
- 2004-06-07 AT AT04776279T patent/ATE411981T1/de not_active IP Right Cessation
- 2004-06-07 RU RU2005138124/04A patent/RU2318810C2/ru not_active IP Right Cessation
- 2004-06-07 CA CA002528321A patent/CA2528321A1/en not_active Abandoned
- 2004-06-07 AU AU2004247676A patent/AU2004247676A1/en not_active Abandoned
- 2004-06-07 BR BRPI0411085-4A patent/BRPI0411085A/pt not_active IP Right Cessation
- 2004-06-07 US US10/560,013 patent/US7351733B2/en not_active Expired - Fee Related
- 2004-06-07 ES ES04776279T patent/ES2314446T3/es not_active Expired - Lifetime
- 2004-06-07 EP EP04776279A patent/EP1654228B1/en not_active Expired - Lifetime
-
2005
- 2005-11-15 IL IL171974A patent/IL171974A0/en unknown
- 2005-12-05 NO NO20055741A patent/NO20055741L/no not_active Application Discontinuation
- 2005-12-09 MA MA28646A patent/MA27880A1/fr unknown
- 2005-12-15 CO CO05126713A patent/CO5660287A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US20060161002A1 (en) | 2006-07-20 |
| EP1654228A1 (en) | 2006-05-10 |
| AU2004247676A1 (en) | 2004-12-23 |
| ATE411981T1 (de) | 2008-11-15 |
| RU2005138124A (ru) | 2006-07-10 |
| IL171974A0 (en) | 2006-04-10 |
| NO20055741D0 (no) | 2005-12-05 |
| DE602004017326D1 (de) | 2008-12-04 |
| US7351733B2 (en) | 2008-04-01 |
| CO5660287A2 (es) | 2006-07-31 |
| WO2004110999A1 (en) | 2004-12-23 |
| NO20055741L (no) | 2006-01-06 |
| JP2007501284A (ja) | 2007-01-25 |
| MA27880A1 (fr) | 2006-05-02 |
| ES2314446T3 (es) | 2009-03-16 |
| KR20060017545A (ko) | 2006-02-23 |
| RU2318810C2 (ru) | 2008-03-10 |
| CA2528321A1 (en) | 2004-12-23 |
| EP1654228B1 (en) | 2008-10-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 5A, 6A, 7A E 8A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012. |