IL166555A0 - Myocardial perfusion imaging a2a receptor agaonists - Google Patents
Myocardial perfusion imaging a2a receptor agaonistsInfo
- Publication number
- IL166555A0 IL166555A0 IL16655505A IL16655505A IL166555A0 IL 166555 A0 IL166555 A0 IL 166555A0 IL 16655505 A IL16655505 A IL 16655505A IL 16655505 A IL16655505 A IL 16655505A IL 166555 A0 IL166555 A0 IL 166555A0
- Authority
- IL
- Israel
- Prior art keywords
- agaonists
- receptor
- myocardial perfusion
- perfusion imaging
- imaging
- Prior art date
Links
- 101150051188 Adora2a gene Proteins 0.000 title 1
- 238000003384 imaging method Methods 0.000 title 1
- 230000002107 myocardial effect Effects 0.000 title 1
- 230000010412 perfusion Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/50—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications
- A61B6/507—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications for determination of haemodynamic parameters, e.g. perfusion CT
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39917602P | 2002-07-29 | 2002-07-29 | |
US39917702P | 2002-07-29 | 2002-07-29 | |
US42690202P | 2002-11-15 | 2002-11-15 | |
US45980303P | 2003-04-02 | 2003-04-02 | |
PCT/US2003/023511 WO2004011010A1 (fr) | 2002-07-29 | 2003-07-29 | Imagerie de perfusion myocardique au moyen d'agonistes de recepteur a2a |
Publications (1)
Publication Number | Publication Date |
---|---|
IL166555A0 true IL166555A0 (en) | 2006-01-15 |
Family
ID=31192376
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL16655505A IL166555A0 (en) | 2002-07-29 | 2005-01-31 | Myocardial perfusion imaging a2a receptor agaonists |
Country Status (12)
Country | Link |
---|---|
US (2) | US7683037B2 (fr) |
EP (1) | EP1524984A1 (fr) |
JP (1) | JP2005538190A (fr) |
KR (1) | KR20050026546A (fr) |
CN (1) | CN1671399A (fr) |
AU (1) | AU2003259264A1 (fr) |
CA (1) | CA2492855C (fr) |
IL (1) | IL166555A0 (fr) |
MX (1) | MXPA05001123A (fr) |
NO (1) | NO20051059L (fr) |
NZ (1) | NZ537975A (fr) |
WO (1) | WO2004011010A1 (fr) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6214807B1 (en) | 1999-06-22 | 2001-04-10 | Cv Therapeutics, Inc. | C-pyrazole 2A A receptor agonists |
USRE47351E1 (en) | 1999-06-22 | 2019-04-16 | Gilead Sciences, Inc. | 2-(N-pyrazolo)adenosines with application as adenosine A2A receptor agonists |
US6403567B1 (en) * | 1999-06-22 | 2002-06-11 | Cv Therapeutics, Inc. | N-pyrazole A2A adenosine receptor agonists |
CA2671940A1 (fr) * | 2000-02-23 | 2001-08-30 | Cv Therapeutics, Inc. | Procede permettant d'identifier des agonistes partiels du recepteur a2a |
US20050020915A1 (en) * | 2002-07-29 | 2005-01-27 | Cv Therapeutics, Inc. | Myocardial perfusion imaging methods and compositions |
JP2005538190A (ja) | 2002-07-29 | 2005-12-15 | シーブイ・セラピューティクス・インコーポレイテッド | 心筋潅流イメージング |
US8470801B2 (en) | 2002-07-29 | 2013-06-25 | Gilead Sciences, Inc. | Myocardial perfusion imaging methods and compositions |
US7526331B2 (en) * | 2003-07-18 | 2009-04-28 | Munn Charles S | Enhanced cardiac radionuclide imaging techniques |
DK1708721T3 (da) * | 2004-01-27 | 2013-09-08 | Gilead Sciences Inc | Billeddannelse af myokardieperfusion under anvendelse af adenosin-receptor-agonister |
CA2583185A1 (fr) * | 2004-10-20 | 2006-04-27 | Cv Therapeutics, Inc. | Utilisation d'agonistes du recepteur de l'adenosine a2a |
JP5042996B2 (ja) * | 2005-05-19 | 2012-10-03 | ギリアード・パロ・アルト・インコーポレイテッド | A1アデノシンレセプターアゴニスト |
KR101494125B1 (ko) | 2006-02-03 | 2015-02-16 | 길리애드 사이언시즈, 인코포레이티드 | A2a-아데노신 수용체 효능제 및 이의 다형체의 제조 방법 |
US20070299089A1 (en) * | 2006-06-22 | 2007-12-27 | Cv Therapeutics, Inc. | Use of A2A Adenosine Receptor Agonists in the Treatment of Ischemia |
RU2459626C2 (ru) * | 2006-09-01 | 2012-08-27 | Гайлид Сайэнсиз, Инк. | Способы и композиции, повышающие переносимость пациентом методов визуализации миокарда |
US20090081120A1 (en) * | 2006-09-01 | 2009-03-26 | Cv Therapeutics, Inc. | Methods and Compositions for Increasing Patient Tolerability During Myocardial Imaging Methods |
EP2066232A1 (fr) * | 2006-09-29 | 2009-06-10 | Cv Therapeutics, Inc. | Procédés d'imagerie myocardique chez des patients ayant un historique de maladie pulmonaire |
WO2008086096A2 (fr) * | 2007-01-03 | 2008-07-17 | Cv Therapeutics, Inc. | Imagerie de perfusion myocardique |
MX2011003168A (es) * | 2008-09-29 | 2011-05-19 | Gilead Sciences Inc | Combinaciones de un agente de control de cantidad y un antagonista del receptor a-2-alfa para utilizarse en metodos de tomografia computarizada de detectores multiples. |
WO2014047446A1 (fr) * | 2012-09-21 | 2014-03-27 | The General Hospital Corporation | Système et procédé pour une tomographie par émission de positons (tep) cardiaque au repos/à l'effort à balayage unique |
WO2014063134A1 (fr) | 2012-10-19 | 2014-04-24 | New York University | Procédés d'inhibition de l'ostéolyse |
US20150290236A1 (en) * | 2012-11-30 | 2015-10-15 | Leiutis Pharmaceuticals Pvt. Ltd. | Pharmaceutical compositions of regadenoson |
CN105997852B (zh) * | 2016-05-15 | 2018-10-09 | 南京海融医药科技股份有限公司 | 一种瑞加诺生注射液及其制备方法 |
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CA2671940A1 (fr) | 2000-02-23 | 2001-08-30 | Cv Therapeutics, Inc. | Procede permettant d'identifier des agonistes partiels du recepteur a2a |
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HU229504B1 (hu) | 2001-11-09 | 2014-01-28 | Gilead Sciences | A2B-adenozinreceptor-antagonisták |
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EP1465631B1 (fr) | 2001-12-20 | 2010-02-24 | OSI Pharmaceuticals, Inc. | Composes pyrimidine antagonistes selectifs des recepteurs a2b, leur synthese et leur utilisation |
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US20050020915A1 (en) * | 2002-07-29 | 2005-01-27 | Cv Therapeutics, Inc. | Myocardial perfusion imaging methods and compositions |
JP2005538190A (ja) | 2002-07-29 | 2005-12-15 | シーブイ・セラピューティクス・インコーポレイテッド | 心筋潅流イメージング |
DK1708721T3 (da) | 2004-01-27 | 2013-09-08 | Gilead Sciences Inc | Billeddannelse af myokardieperfusion under anvendelse af adenosin-receptor-agonister |
CA2583986A1 (fr) | 2004-10-15 | 2006-04-27 | Cv Therapeutics, Inc. | Procede de prevention et de traitement du remodelage des voies respiratoires et de l'inflammation pulmonaire par le biais d'antagonistes du recepteur d'adenosine a<sb>2b</sb> |
CA2583185A1 (fr) * | 2004-10-20 | 2006-04-27 | Cv Therapeutics, Inc. | Utilisation d'agonistes du recepteur de l'adenosine a2a |
JP2008527003A (ja) | 2005-01-12 | 2008-07-24 | キング・ファーマシューティカルズ・リサーチ・アンド・デベロプメント・インコーポレイティッド | 喘息又は気管支痙攣の既往歴を有する患者における心筋機能不全を検出する方法 |
KR101494125B1 (ko) | 2006-02-03 | 2015-02-16 | 길리애드 사이언시즈, 인코포레이티드 | A2a-아데노신 수용체 효능제 및 이의 다형체의 제조 방법 |
US20070299089A1 (en) * | 2006-06-22 | 2007-12-27 | Cv Therapeutics, Inc. | Use of A2A Adenosine Receptor Agonists in the Treatment of Ischemia |
US20090081120A1 (en) | 2006-09-01 | 2009-03-26 | Cv Therapeutics, Inc. | Methods and Compositions for Increasing Patient Tolerability During Myocardial Imaging Methods |
RU2459626C2 (ru) * | 2006-09-01 | 2012-08-27 | Гайлид Сайэнсиз, Инк. | Способы и композиции, повышающие переносимость пациентом методов визуализации миокарда |
EP2066232A1 (fr) * | 2006-09-29 | 2009-06-10 | Cv Therapeutics, Inc. | Procédés d'imagerie myocardique chez des patients ayant un historique de maladie pulmonaire |
WO2008086096A2 (fr) * | 2007-01-03 | 2008-07-17 | Cv Therapeutics, Inc. | Imagerie de perfusion myocardique |
MX2011003168A (es) | 2008-09-29 | 2011-05-19 | Gilead Sciences Inc | Combinaciones de un agente de control de cantidad y un antagonista del receptor a-2-alfa para utilizarse en metodos de tomografia computarizada de detectores multiples. |
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2003
- 2003-07-29 JP JP2005505626A patent/JP2005538190A/ja active Pending
- 2003-07-29 US US10/629,368 patent/US7683037B2/en not_active Expired - Fee Related
- 2003-07-29 CA CA2492855A patent/CA2492855C/fr not_active Expired - Lifetime
- 2003-07-29 WO PCT/US2003/023511 patent/WO2004011010A1/fr active Application Filing
- 2003-07-29 EP EP03771950A patent/EP1524984A1/fr not_active Withdrawn
- 2003-07-29 KR KR1020057001708A patent/KR20050026546A/ko not_active Application Discontinuation
- 2003-07-29 MX MXPA05001123A patent/MXPA05001123A/es active IP Right Grant
- 2003-07-29 AU AU2003259264A patent/AU2003259264A1/en not_active Abandoned
- 2003-07-29 NZ NZ537975A patent/NZ537975A/en not_active IP Right Cessation
- 2003-07-29 CN CNA038175924A patent/CN1671399A/zh active Pending
-
2005
- 2005-01-31 IL IL16655505A patent/IL166555A0/xx unknown
- 2005-02-25 NO NO20051059A patent/NO20051059L/no not_active Application Discontinuation
-
2010
- 2010-01-27 US US12/695,096 patent/US8183226B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP2005538190A (ja) | 2005-12-15 |
WO2004011010A1 (fr) | 2004-02-05 |
US20100272645A1 (en) | 2010-10-28 |
NZ537975A (en) | 2007-08-31 |
CN1671399A (zh) | 2005-09-21 |
US8183226B2 (en) | 2012-05-22 |
NO20051059L (no) | 2005-02-25 |
US7683037B2 (en) | 2010-03-23 |
US20040064039A1 (en) | 2004-04-01 |
MXPA05001123A (es) | 2005-04-29 |
EP1524984A1 (fr) | 2005-04-27 |
CA2492855C (fr) | 2012-09-18 |
KR20050026546A (ko) | 2005-03-15 |
CA2492855A1 (fr) | 2004-02-05 |
AU2003259264A1 (en) | 2004-02-16 |
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