IL165857A0 - Electrochemiluminescence flow cell and flow cell components - Google Patents

Electrochemiluminescence flow cell and flow cell components

Info

Publication number
IL165857A0
IL165857A0 IL16585704A IL16585704A IL165857A0 IL 165857 A0 IL165857 A0 IL 165857A0 IL 16585704 A IL16585704 A IL 16585704A IL 16585704 A IL16585704 A IL 16585704A IL 165857 A0 IL165857 A0 IL 165857A0
Authority
IL
Israel
Prior art keywords
flow cell
electrochemiluminescence
components
cell components
flow
Prior art date
Application number
IL16585704A
Other languages
English (en)
Original Assignee
Bioveris Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioveris Corp filed Critical Bioveris Corp
Publication of IL165857A0 publication Critical patent/IL165857A0/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76—Chemiluminescence; Bioluminescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/66—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
    • G01N21/69—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence specially adapted for fluids, e.g. molten metal
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0389—Windows

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Optical Measuring Cells (AREA)
IL16585704A 2002-06-20 2004-12-19 Electrochemiluminescence flow cell and flow cell components IL165857A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39081602P 2002-06-20 2002-06-20
PCT/US2003/019691 WO2004001380A2 (fr) 2002-06-20 2003-06-19 Cuve a circulation a electrochimioluminescence et elements de cuve a circulation

Publications (1)

Publication Number Publication Date
IL165857A0 true IL165857A0 (en) 2006-01-15

Family

ID=30000630

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16585704A IL165857A0 (en) 2002-06-20 2004-12-19 Electrochemiluminescence flow cell and flow cell components

Country Status (8)

Country Link
US (2) US7553448B2 (fr)
EP (1) EP1552284A4 (fr)
JP (1) JP2005530183A (fr)
KR (1) KR20050013592A (fr)
AU (1) AU2003249350A1 (fr)
CA (1) CA2493905A1 (fr)
IL (1) IL165857A0 (fr)
WO (1) WO2004001380A2 (fr)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6200531B1 (en) * 1998-05-11 2001-03-13 Igen International, Inc. Apparatus for carrying out electrochemiluminescence test measurements
US7560269B2 (en) 2002-12-20 2009-07-14 Acea Biosciences, Inc. Real time electronic cell sensing system and applications for cytotoxicity profiling and compound assays
US7470533B2 (en) * 2002-12-20 2008-12-30 Acea Biosciences Impedance based devices and methods for use in assays
US8263375B2 (en) 2002-12-20 2012-09-11 Acea Biosciences Dynamic monitoring of activation of G-protein coupled receptor (GPCR) and receptor tyrosine kinase (RTK) in living cells using real-time microelectronic cell sensing technology
DE10239098A1 (de) * 2002-08-26 2004-03-11 Roche Diagnostics Gmbh Erzeugung von Chemilumineszenz durch Wasserstoff
US10215748B2 (en) 2002-12-20 2019-02-26 Acea Biosciences, Inc. Using impedance-based cell response profiling to identify putative inhibitors for oncogene addicted targets or pathways
US11346797B2 (en) 2002-12-20 2022-05-31 Agilent Technologies, Inc. System and method for monitoring cardiomyocyte beating, viability, morphology and electrophysiological properties
US9612234B2 (en) 2008-05-05 2017-04-04 Acea Biosciences, Inc. Data analysis of impedance-based cardiomyocyte-beating signals as detected on real-time cell analysis (RTCA) cardio instruments
US10539523B2 (en) 2002-12-20 2020-01-21 Acea Biosciences, Inc. System and method for monitoring cardiomyocyte beating, viability, morphology, and electrophysiological properties
US10551371B2 (en) 2003-11-10 2020-02-04 Acea Biosciences, Inc. System and method for monitoring cardiomyocyte beating, viability and morphology and for screening for pharmacological agents which may induce cardiotoxicity or modulate cardiomyocyte function
EP1636571A1 (fr) * 2003-06-13 2006-03-22 Applera Corporation Electrode electrochimioluminescente
EP1692258A4 (fr) 2003-11-12 2007-03-21 Xiao Xu Systemes de detection de cellules electroniques en temps reel pour des epreuves a base de cellules
DE102004031370B4 (de) * 2004-06-29 2022-03-24 Siemens Aktiengesellschaft Vorrichtung und Verfahren zur Emulation einer Gegenelektrode in einem monolithisch integrierten elektrochemischen Analysesystem
WO2007002580A2 (fr) * 2005-06-23 2007-01-04 Bioveris Corporation Dispositif de detection et procedes associes a ce dispositif
FR2906237B1 (fr) * 2006-09-22 2008-12-19 Commissariat Energie Atomique Composants fluidiques double-face
CN100451626C (zh) * 2006-09-30 2009-01-14 福州大学 微量电化学发光检测池
DK2271938T3 (da) 2008-04-11 2014-05-12 Univ Texas Fremgangsmåde og apparat til nanopartikel-elektrogenereret kemiluminescens-amplifikation
EP2291645B1 (fr) 2008-05-05 2015-09-09 Acea Biosciences, Inc. Surveillance sans marqueur d'un couplage excitation-contraction et cellules pouvant être excitées utilisant des systèmes fondés sur l'impédance avec une résolution dans le temps de l'ordre de la milliseconde
AU2009244904B2 (en) 2008-05-08 2014-04-17 Board Of Regents Of The University Of Texas System Luminescent nanostructured materials for use in electrogenerated chemiluminescence
WO2011120024A1 (fr) 2010-03-25 2011-09-29 Quantalife, Inc. Génération de gouttelettes pour dosages sur gouttelettes
US11130128B2 (en) 2008-09-23 2021-09-28 Bio-Rad Laboratories, Inc. Detection method for a target nucleic acid
US9156010B2 (en) 2008-09-23 2015-10-13 Bio-Rad Laboratories, Inc. Droplet-based assay system
US10512910B2 (en) 2008-09-23 2019-12-24 Bio-Rad Laboratories, Inc. Droplet-based analysis method
EP2389447B1 (fr) 2009-01-23 2014-11-05 University of Maryland, Baltimore County Système de détection de la chlorophylle et de la turbidité
US9075042B2 (en) 2012-05-15 2015-07-07 Wellstat Diagnostics, Llc Diagnostic systems and cartridges
US9625465B2 (en) 2012-05-15 2017-04-18 Defined Diagnostics, Llc Clinical diagnostic systems
US9213043B2 (en) 2012-05-15 2015-12-15 Wellstat Diagnostics, Llc Clinical diagnostic system including instrument and cartridge
GB201216867D0 (en) * 2012-09-20 2012-11-07 Univ Southampton Apparatus for sensing at least one parameter in water
JP6239243B2 (ja) * 2013-02-08 2017-11-29 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 自動分析装置
JP7039481B2 (ja) * 2016-03-11 2022-03-22 エフ．ホフマン－ラ ロシュ アーゲー 電気化学発光検出における分枝鎖アミン
CN105891525B (zh) * 2016-07-05 2018-08-21 深圳普门科技有限公司 全自动电化学发光免疫分析仪的检测装置
CN110582569B (zh) 2017-03-03 2024-04-02 安捷伦科技有限公司 用于iPSC和ESC衍生的心肌细胞的功能成熟的方法和系统
CN110412021B (zh) * 2019-08-06 2022-04-29 华南师范大学 一种共享双性电极阴极的电化学发光微流控芯片及其应用
USD941488S1 (en) 2020-02-07 2022-01-18 Agilent Technologies, Inc. Instrument for analyzing biological cells
US20230074431A1 (en) * 2020-02-11 2023-03-09 Massachusetts Inst Technology Devices and methods for determining phosphate levels in natural water
CN111693515B (zh) * 2020-05-07 2022-06-17 四川轻化工大学 一种流式电化学发光实时检测装置及检测方法
MX2023010037A (es) * 2021-02-26 2023-11-22 Elips Diagnostics Inc Nuevo co-reactivo de electroquimioluminiscencia y sistema de electroquimioluminiscencia que comprende el mismo.

Family Cites Families (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3816795A (en) 1965-10-23 1974-06-11 American Cyanamid Co Method for providing electroluminescent light from a polycyclic heterocyclic compound in an aprotic solvent under electric current
US3583230A (en) 1968-06-12 1971-06-08 Sondell Research Dev Co Sample injection method and apparatus
NL7001235A (fr) 1970-01-29 1971-08-02
US3784928A (en) * 1971-06-04 1974-01-08 Rca Ltd Gas discharge device and electrode for use therein
GB1509186A (en) 1974-05-08 1978-05-04 Secr Social Service Brit Specimen agitation apparatus
US3900418A (en) * 1973-04-12 1975-08-19 Bell Northern Research Ltd Electrochemical luminescent solutions and devices incorporating such solutions
FR2247732A1 (fr) 1973-10-16 1975-05-09 Accumulateurs Fixes
US3984688A (en) 1975-04-21 1976-10-05 Source Gas Analyzers, Inc. Monitor for detection of chemiluminescent reactions
US4132605A (en) * 1976-12-27 1979-01-02 Rockwell International Corporation Method for evaluating the quality of electroplating baths
US4210724A (en) 1977-03-28 1980-07-01 Olympus Optical Co., Ltd. Apparatus for liquid disposal and distribution in automatic culture system
DE2735247C3 (de) * 1977-08-04 1980-10-16 Heusler, Konrad, Prof. Dr., 3392 Clausthal-Zellerfeld Verfahren zur spektralphotometrischen Untersuchung von Produkten elektrochemischer Reaktionen
US4213703A (en) 1978-05-30 1980-07-22 Beckman Instruments, Inc. Photometer with stationary sample holder and rotatable shutter
US4443713A (en) 1978-10-30 1984-04-17 Phillips Petroleum Company Waveform generator
US4280815A (en) 1979-06-18 1981-07-28 Technicon Instruments Corporation Electrochemiluminescent immunoassay and apparatus therefor
DE3013765A1 (de) 1980-04-10 1981-10-15 Philips Patentverwaltung Gmbh, 2000 Hamburg Detektroranordnung, insbesondere fuer die fluessigkeitschromatografie
US4297105A (en) 1980-06-27 1981-10-27 Alcan Research And Development Limited Automatic photometric titrator
US4303410A (en) 1980-11-03 1981-12-01 The United States Of America As Represented By The Secretary Of The Navy Light burst activity analyzer
EP0091924A1 (fr) 1981-10-29 1983-10-26 Commonwealth Scientific And Industrial Research Organisation Electro-analyse par impulsion
US4537861A (en) 1983-02-03 1985-08-27 Elings Virgil B Apparatus and method for homogeneous immunoassay
EP0141780A1 (fr) * 1983-10-11 1985-05-15 Battelle Memorial Institute Procédé pour la décontamination électrochimique de l'eau
US5500188A (en) 1984-03-01 1996-03-19 Molecular Devices Corporation Device for photoresponsive detection and discrimination
US5238808A (en) 1984-10-31 1993-08-24 Igen, Inc. Luminescent metal chelate labels and means for detection
US5310687A (en) 1984-10-31 1994-05-10 Igen, Inc. Luminescent metal chelate labels and means for detection
JPS6235326A (ja) 1985-08-09 1987-02-16 Canon Inc 表示素子
US5147806A (en) 1988-04-29 1992-09-15 Igen, Inc. Method and apparatus for conducting electrochemiluminescence measurements
WO1987007386A1 (fr) 1986-05-22 1987-12-03 Unilever Plc Procede immunoanalytique en phase solide
US4849340A (en) 1987-04-03 1989-07-18 Cardiovascular Diagnostics, Inc. Reaction system element and method for performing prothrombin time assay
JPS6443745A (en) 1987-08-12 1989-02-16 Hitachi Ltd Instrument for measuring light emitted by organism
US5088088A (en) * 1988-02-05 1992-02-11 Tandy Corporation Dye-polymer optical data storage media with improved recording sensitivity
JPH01247962A (ja) 1988-03-29 1989-10-03 Hisaka Works Ltd ヒートポンプ
US5093268A (en) 1988-04-28 1992-03-03 Igen, Inc. Apparatus for conducting a plurality of simultaneous measurements of electrochemiluminescent phenomena
US5746974A (en) 1988-11-03 1998-05-05 Igen International, Inc. Apparatus for improved luminescence assays using particle concentration, electrochemical generation of chemiluminescence and chemiluminescence detection
US5061445A (en) 1988-11-03 1991-10-29 Igen, Inc. Apparatus for conducting measurements of electrochemiluminescent phenomena
US5068088A (en) 1988-11-03 1991-11-26 Igen, Inc. Method and apparatus for conducting electrochemiluminescent measurements
US5296191A (en) 1988-11-03 1994-03-22 Igen, Inc. Method and apparatus for conducting electrochemiluminescent measurements
US5779976A (en) 1988-11-03 1998-07-14 Igen International, Inc. Apparatus for improved luminescence assays
US5247243A (en) 1988-11-03 1993-09-21 Igen, Inc. Method and apparatus for conducting electrochemiluminescent measurements
US5705402A (en) 1988-11-03 1998-01-06 Igen International, Inc. Method and apparatus for magnetic microparticulate based luminescence assay including plurality of magnets
US5324457A (en) * 1989-10-02 1994-06-28 Board Of Regents, The University Of Tx System Devices and methods for generating electrogenerated chemiluminescence
US5189549A (en) 1990-02-26 1993-02-23 Molecular Displays, Inc. Electrochromic, electroluminescent and electrochemiluminescent displays
US5298427A (en) 1990-04-24 1994-03-29 The Board Of Trustees Of The University Of Arkansas Chemiluminescent detection of amino acids
US5132227A (en) 1990-05-02 1992-07-21 Batelle Memorial Institute Monitoring formaldehyde
IL100867A (en) 1991-02-06 1995-12-08 Igen Inc Method and device for improved luminescence testing
JPH0534345A (ja) 1991-02-19 1993-02-09 Tdk Corp 化学発光を利用する抗原・抗体の測定方法
US5376313A (en) 1992-03-27 1994-12-27 Abbott Laboratories Injection molding a plastic assay cuvette having low birefringence
US5466416A (en) 1993-05-14 1995-11-14 Ghaed; Ali Apparatus and methods for carrying out electrochemiluminescence test measurements
US5541113A (en) 1993-09-22 1996-07-30 Beckman Instruments, Inc. Method for detecting an analyte using an electrochemical luminescent transition metal label
US5965452A (en) * 1996-07-09 1999-10-12 Nanogen, Inc. Multiplexed active biologic array
US5591321A (en) * 1993-11-02 1997-01-07 Electric Power Research Institute Detection of fluids with metal-insulator-semiconductor sensors
US5429893A (en) 1994-02-04 1995-07-04 Motorola, Inc. Electrochemical capacitors having dissimilar electrodes
JPH07286894A (ja) * 1994-04-18 1995-10-31 Fujitsu Ltd 赤外線検知装置の製造方法
US5786141A (en) 1994-08-26 1998-07-28 Bard; Allen J. Electrogenerated chemiluminescence labels for analysis and/or referencing
DE4435107C1 (de) 1994-09-30 1996-04-04 Biometra Biomedizinische Analy Miniaturisierter Fluß-Thermocycler
US5744367A (en) 1994-11-10 1998-04-28 Igen International, Inc. Magnetic particle based electrochemiluminescent detection apparatus and method
US5538687A (en) 1994-12-16 1996-07-23 Behringer Mannheim Gmbh Apparatus for generating optically detectable signals by applying electrical potentials to sample liquids
US5993740A (en) 1995-01-20 1999-11-30 Hitachi, Ltd. Immunoassay method and analyzer using magnetic particles
CA2704228C (fr) 1995-03-10 2013-10-22 Meso Scale Technologies, Llc Essai par electrochimioluminescence multispecifique et multirangee
US6207369B1 (en) 1995-03-10 2001-03-27 Meso Scale Technologies, Llc Multi-array, multi-specific electrochemiluminescence testing
US5589136A (en) 1995-06-20 1996-12-31 Regents Of The University Of California Silicon-based sleeve devices for chemical reactions
EP0791821A4 (fr) 1995-09-12 1999-10-27 Eisai Co Ltd Procede et appareil de detection d'electrochemiluminescence
WO1997016784A1 (fr) * 1995-10-30 1997-05-09 Fumio Negoro Procede de production de logiciels, processeur et support d'enregistrement
US5973443A (en) * 1996-05-06 1999-10-26 Alliedsignal Inc. Spark plug electrode tip for internal combustion engine
DK0914203T3 (da) * 1996-05-20 2001-07-23 Dinex As Fremgangsmåde og rekator til elektrokemisk omsætning af et i et fluidum uopløseligt material fx sodpartikler
US5833925A (en) 1996-11-13 1998-11-10 Beckman Instruments, Inc. Automatic chemistry analyzer with improved ion selective electrode assembly
DE19725190A1 (de) 1997-06-14 1998-12-17 Innova Gmbh Vorrichtungen mit integrierten Elektroden aus elektrisch leitfähigen Kunststoffen
SE520302C2 (sv) 1997-09-15 2003-06-24 Vito Metalljonspecifik kapacitanssensor
US6200531B1 (en) * 1998-05-11 2001-03-13 Igen International, Inc. Apparatus for carrying out electrochemiluminescence test measurements
GB9815042D0 (en) * 1998-07-10 1998-09-09 Imperial College Detector
US6136268A (en) * 1999-08-17 2000-10-24 Orion Diagnostica Method for luminescence measurements
EP1893990B1 (fr) 2005-06-03 2018-05-02 Board of Regents of the University of Texas System Electrochimie et chimioluminescence electrogeneree avec une electrode faradique unique

Also Published As

Publication number Publication date
WO2004001380A2 (fr) 2003-12-31
US20040090168A1 (en) 2004-05-13
US20090246076A1 (en) 2009-10-01
CA2493905A1 (fr) 2003-12-31
EP1552284A2 (fr) 2005-07-13
AU2003249350A1 (en) 2004-01-06
US7553448B2 (en) 2009-06-30
JP2005530183A (ja) 2005-10-06
AU2003249350A8 (en) 2004-01-06
KR20050013592A (ko) 2005-02-04
EP1552284A4 (fr) 2008-11-05
WO2004001380A3 (fr) 2004-04-08

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