IL165487A0 - 1-(aminoalkyl)-3-sulfonylazaindoles as 5-hydroxyptamine-6 ligands - Google Patents

1-(aminoalkyl)-3-sulfonylazaindoles as 5-hydroxyptamine-6 ligands

Info

Publication number
IL165487A0
IL165487A0 IL16548703A IL16548703A IL165487A0 IL 165487 A0 IL165487 A0 IL 165487A0 IL 16548703 A IL16548703 A IL 16548703A IL 16548703 A IL16548703 A IL 16548703A IL 165487 A0 IL165487 A0 IL 165487A0
Authority
IL
Israel
Prior art keywords
sulfonylazaindoles
hydroxyptamine
aminoalkyl
ligands
Prior art date
Application number
IL16548703A
Other languages
English (en)
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of IL165487A0 publication Critical patent/IL165487A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL16548703A 2002-06-04 2003-06-03 1-(aminoalkyl)-3-sulfonylazaindoles as 5-hydroxyptamine-6 ligands IL165487A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38550202P 2002-06-04 2002-06-04
PCT/US2003/017466 WO2003101990A1 (en) 2002-06-04 2003-06-03 1-(aminoalkyl)-3-sulfonylazaindoles as 5-hydroxytryptamine-6 ligands

Publications (1)

Publication Number Publication Date
IL165487A0 true IL165487A0 (en) 2006-01-15

Family

ID=29712180

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16548703A IL165487A0 (en) 2002-06-04 2003-06-03 1-(aminoalkyl)-3-sulfonylazaindoles as 5-hydroxyptamine-6 ligands

Country Status (25)

Country Link
US (3) US6825212B2 (de)
EP (1) EP1509522B1 (de)
JP (1) JP2005532349A (de)
KR (1) KR20050013565A (de)
CN (1) CN1315827C (de)
AR (1) AR040047A1 (de)
AT (1) ATE355289T1 (de)
AU (1) AU2003239954A1 (de)
BR (1) BR0311591A (de)
CA (1) CA2486191A1 (de)
DE (1) DE60312155T2 (de)
DK (1) DK1509522T3 (de)
EC (1) ECSP045474A (de)
ES (1) ES2282637T3 (de)
IL (1) IL165487A0 (de)
MX (1) MXPA04011331A (de)
NO (1) NO20044763L (de)
NZ (1) NZ536959A (de)
PT (1) PT1509522E (de)
RU (1) RU2315048C2 (de)
SI (1) SI1509522T1 (de)
TW (1) TW200408638A (de)
UA (1) UA78999C2 (de)
WO (1) WO2003101990A1 (de)
ZA (1) ZA200500022B (de)

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US7504509B2 (en) 2003-12-19 2009-03-17 Plexxikon, Inc. Compounds and methods for development of Ret modulators
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TW200800959A (en) * 2005-06-10 2008-01-01 Wyeth Corp Piperazine-piperidine antagonists and agonists of the 5-HT1a receptor
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TW200811144A (en) * 2006-06-09 2008-03-01 Wyeth Corp Crystalline forms of 6-methoxy-8-[4-(1-(5-fluoro)-quinolin-8-yl-piperidin-4-yl)-piperazin-1-yl]-quinoline
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WO2008063888A2 (en) 2006-11-22 2008-05-29 Plexxikon, Inc. Compounds modulating c-fms and/or c-kit activity and uses therefor
US20080262228A1 (en) * 2006-11-28 2008-10-23 Wyeth Metabolites of 5-fluoro-8- quinoline and methods of preparation and uses thereof
EP2124951B1 (de) 2006-12-21 2014-05-21 Vertex Pharmaceuticals Inc. 5-cyan0-4- (pyrrolo [2, 3b]pyridine-3-l)-pyrimidinderivate als proteinkinasehemmer
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AU2008254588B2 (en) * 2007-05-21 2013-01-17 Sgx Pharmaceuticals, Inc. Heterocyclic kinase modulators
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JP2011507835A (ja) 2007-12-21 2011-03-10 アンドレイ・アレクサンドロビッチ・イワシェンコ α−アドレナリン受容体、ドーパミン、ヒスタミン、イミダゾリン及びセロトニン受容体のリガンド並びにその使用
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Also Published As

Publication number Publication date
PT1509522E (pt) 2007-05-31
SI1509522T1 (sl) 2007-06-30
MXPA04011331A (es) 2005-02-14
NZ536959A (en) 2007-04-27
KR20050013565A (ko) 2005-02-04
CN1315827C (zh) 2007-05-16
RU2315048C2 (ru) 2008-01-20
CA2486191A1 (en) 2003-12-11
AR040047A1 (es) 2005-03-09
CN1659166A (zh) 2005-08-24
DE60312155D1 (de) 2007-04-12
US6825212B2 (en) 2004-11-30
UA78999C2 (en) 2007-05-10
ES2282637T3 (es) 2007-10-16
TW200408638A (en) 2004-06-01
RU2004139068A (ru) 2005-06-27
US7074792B2 (en) 2006-07-11
US20050085481A1 (en) 2005-04-21
ECSP045474A (es) 2005-01-28
DE60312155T2 (de) 2007-11-22
US7585873B2 (en) 2009-09-08
NO20044763L (no) 2005-02-28
WO2003101990A1 (en) 2003-12-11
US20060148831A1 (en) 2006-07-06
ATE355289T1 (de) 2006-03-15
BR0311591A (pt) 2005-03-01
US20030236278A1 (en) 2003-12-25
DK1509522T3 (da) 2007-04-16
EP1509522A1 (de) 2005-03-02
EP1509522B1 (de) 2007-02-28
HK1071371A1 (en) 2005-07-15
AU2003239954A1 (en) 2003-12-19
ZA200500022B (en) 2006-06-28
JP2005532349A (ja) 2005-10-27

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