IL163559A0 - Powder inhalation containing cgrp-antagonist bibn4096 and method for the production thereof - Google Patents

Powder inhalation containing cgrp-antagonist bibn4096 and method for the production thereof

Info

Publication number
IL163559A0
IL163559A0 IL16355903A IL16355903A IL163559A0 IL 163559 A0 IL163559 A0 IL 163559A0 IL 16355903 A IL16355903 A IL 16355903A IL 16355903 A IL16355903 A IL 16355903A IL 163559 A0 IL163559 A0 IL 163559A0
Authority
IL
Israel
Prior art keywords
production
powder inhalation
inhalation containing
containing cgrp
bibn4096
Prior art date
Application number
IL16355903A
Other languages
English (en)
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of IL163559A0 publication Critical patent/IL163559A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Otolaryngology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL16355903A 2002-02-20 2003-02-17 Powder inhalation containing cgrp-antagonist bibn4096 and method for the production thereof IL163559A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10207026A DE10207026A1 (de) 2002-02-20 2002-02-20 Pulverinhalativum, enthaltend den CGRP-Antagonisten BIBN4096 und Verfahren zu dessen Herstellung
PCT/EP2003/001563 WO2003070215A1 (de) 2002-02-20 2003-02-17 Pulverinhalativum, enthaltend den cgrp-antagonisten bibn4096 und verfahren zu dessen herstellung

Publications (1)

Publication Number Publication Date
IL163559A0 true IL163559A0 (en) 2005-12-18

Family

ID=27635158

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16355903A IL163559A0 (en) 2002-02-20 2003-02-17 Powder inhalation containing cgrp-antagonist bibn4096 and method for the production thereof

Country Status (22)

Country Link
EP (1) EP1478338B1 (ja)
JP (1) JP4085063B2 (ja)
KR (1) KR20040089646A (ja)
CN (1) CN1638728A (ja)
AR (1) AR038572A1 (ja)
AT (1) ATE299016T1 (ja)
AU (1) AU2003208862A1 (ja)
BR (1) BR0307821A (ja)
CA (1) CA2476621A1 (ja)
DE (2) DE10207026A1 (ja)
EA (1) EA200401010A1 (ja)
EC (1) ECSP045241A (ja)
ES (1) ES2244922T3 (ja)
HR (1) HRP20040747A2 (ja)
IL (1) IL163559A0 (ja)
MX (1) MXPA04008183A (ja)
NO (1) NO20043865L (ja)
PE (1) PE20030832A1 (ja)
PL (1) PL371315A1 (ja)
TW (1) TW200304376A (ja)
UY (1) UY27674A1 (ja)
WO (1) WO2003070215A1 (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10338402A1 (de) * 2003-08-18 2005-03-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Sprühgetrocknetes, amorphes BIBN 4096, Verfahren zu dessen Herstellung sowie dessen Verwendung als Inhalativum
DE10338403A1 (de) * 2003-08-18 2005-03-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverformulierung, enthaltend den CGRP-Antagonisten 1-[N2-[3,5-Dibrom-N-[[4-(3,4-dihydro-2(1H)-oxochinazolin-3-yl]-1-piperidinyl]carbonyl]-D-tyrosyl]-L-lysyl]-4-(4-pyrindinyl)-piperazin, Verfahren zu dessen Herstellung sowie dessen Verwendung als Inhalativum
DE10338407A1 (de) * 2003-08-18 2005-03-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Inhalationspulver enthaltend den CGRP-Antagonisten 1-[N2-[3,5-Dibrom-N-[[4-(3,4-dihydro-2(1H)-oxochinazolin-3-yl)-1-piperidinyl]carbonyl]-D-tyrosyl]-L-lysyl]-4-(4-pyridinyl)-piperazin
DE10338399A1 (de) * 2003-08-18 2005-03-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Mikropartikel, enthaltend den CGRP-Antagonisten 1-[N2-[3,5-Dibrom-N-[[4-(3,4-dihydro-2(1H)-oxochinazolin-3-yl)-1-piperidinyl]carbonyl]-D-tyrosyl]-L-Iysyl]-4-(4-pyridinyl)-piperazin, Verfahren zu deren Herstellung sowie deren Verwendung als Inhalaltionspulver
SG11201510426PA (en) * 2013-06-19 2016-01-28 Aicuris Anti Infective Cures Gmbh Amorphous letermovir and solid pharmaceutical formulations thereof for oral administration

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1242211A (en) * 1967-08-08 1971-08-11 Fisons Pharmaceuticals Ltd Pharmaceutical composition
DE19937304C2 (de) * 1999-08-10 2003-08-21 Boehringer Ingelheim Pharma Verwendung von CGRP-Antagonisten zur Bekämpfung menopausaler Hitzewallungen
MXPA02004193A (es) * 1999-10-29 2002-12-13 Inhale Therapeutic Syst Composiciones de polvo seco que tienen caracteristicas de dispersion mejoradas.
DE10139410A1 (de) * 2001-08-17 2003-02-27 Boehringer Ingelheim Pharma Verwendung von BIBN4096 in Kombination mit anderen Arzneistoffen gegen Migräne für die Behandlung von Migräne

Also Published As

Publication number Publication date
WO2003070215A1 (de) 2003-08-28
AR038572A1 (es) 2005-01-19
DE50300736D1 (de) 2005-08-11
JP4085063B2 (ja) 2008-04-30
ATE299016T1 (de) 2005-07-15
NO20043865L (no) 2004-09-15
BR0307821A (pt) 2004-12-14
PE20030832A1 (es) 2003-11-20
EA200401010A1 (ru) 2005-02-24
DE10207026A1 (de) 2003-08-28
ES2244922T3 (es) 2005-12-16
MXPA04008183A (es) 2004-11-26
UY27674A1 (es) 2003-09-30
PL371315A1 (en) 2005-06-13
HRP20040747A2 (en) 2005-02-28
CN1638728A (zh) 2005-07-13
KR20040089646A (ko) 2004-10-21
CA2476621A1 (en) 2003-08-28
JP2005529849A (ja) 2005-10-06
TW200304376A (en) 2003-10-01
ECSP045241A (es) 2004-09-28
EP1478338A1 (de) 2004-11-24
EP1478338B1 (de) 2005-07-06
AU2003208862A1 (en) 2003-09-09

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