IL159084A0 - Tetrahydroisoquinoline carboxylic acid derivatives and pharmaceutical compositions containing the same - Google Patents
Tetrahydroisoquinoline carboxylic acid derivatives and pharmaceutical compositions containing the sameInfo
- Publication number
- IL159084A0 IL159084A0 IL15908402A IL15908402A IL159084A0 IL 159084 A0 IL159084 A0 IL 159084A0 IL 15908402 A IL15908402 A IL 15908402A IL 15908402 A IL15908402 A IL 15908402A IL 159084 A0 IL159084 A0 IL 159084A0
- Authority
- IL
- Israel
- Prior art keywords
- carboxylic acid
- same
- pharmaceutical compositions
- compositions containing
- acid derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001161488 | 2001-05-29 | ||
| PCT/JP2002/005098 WO2002096904A1 (fr) | 2001-05-29 | 2002-05-27 | Nouveaux derives heterocycliques et utilisation medicale de ces derives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL159084A0 true IL159084A0 (en) | 2004-05-12 |
Family
ID=19004755
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15908402A IL159084A0 (en) | 2001-05-29 | 2002-05-27 | Tetrahydroisoquinoline carboxylic acid derivatives and pharmaceutical compositions containing the same |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US6872732B2 (xx) |
| EP (1) | EP1398313A4 (xx) |
| JP (1) | JP4279137B2 (xx) |
| KR (1) | KR100874677B1 (xx) |
| CN (1) | CN1522253A (xx) |
| AR (1) | AR036037A1 (xx) |
| AU (1) | AU2002308891B2 (xx) |
| BR (1) | BR0209735A (xx) |
| CA (1) | CA2448639A1 (xx) |
| CO (1) | CO5540322A2 (xx) |
| CZ (1) | CZ20033415A3 (xx) |
| HU (1) | HUP0400023A2 (xx) |
| IL (1) | IL159084A0 (xx) |
| MX (1) | MXPA03010867A (xx) |
| NO (1) | NO326559B1 (xx) |
| NZ (1) | NZ530313A (xx) |
| PL (1) | PL367676A1 (xx) |
| RU (1) | RU2287529C2 (xx) |
| TW (1) | TWI243172B (xx) |
| WO (1) | WO2002096904A1 (xx) |
| YU (1) | YU94203A (xx) |
| ZA (1) | ZA200309513B (xx) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100898358B1 (ko) * | 2001-05-29 | 2009-05-20 | 교토 야쿠힝 고교 가부시키가이샤 | 신규 복소환 화합물 및 그 의약 용도 |
| US6833380B2 (en) | 2002-03-07 | 2004-12-21 | Warner-Lambert Company, Llc | Compounds that modulate PPAR activity and methods of preparation |
| US6867224B2 (en) | 2002-03-07 | 2005-03-15 | Warner-Lambert Company | Compounds that modulate PPAR activity and methods of preparation |
| AU2003300131A1 (en) * | 2003-01-06 | 2004-11-04 | Eli Lilly And Company | Indole derivatives as ppar modulators |
| US7244763B2 (en) * | 2003-04-17 | 2007-07-17 | Warner Lambert Company Llc | Compounds that modulate PPAR activity and methods of preparation |
| US6987118B2 (en) | 2003-05-21 | 2006-01-17 | Pfizer Inc. | Tetrahydroisoquinoline derivatives as PPAR-alpha activators |
| JP4805552B2 (ja) * | 2003-05-30 | 2011-11-02 | 武田薬品工業株式会社 | 縮合環化合物 |
| EP1630152A4 (en) * | 2003-05-30 | 2009-09-23 | Takeda Pharmaceutical | CONNECTION WITH CONDENSED RING |
| TWI359810B (en) * | 2004-11-04 | 2012-03-11 | Mitsubishi Tanabe Pharma Corp | Carboxylic acid derivative containing thiazole rin |
| WO2007126043A1 (ja) * | 2006-04-27 | 2007-11-08 | Mitsubishi Tanabe Pharma Corporation | チアゾール環を含むカルボン酸誘導体の医薬用途 |
| JPWO2012033195A1 (ja) * | 2010-09-10 | 2014-01-20 | 京都薬品工業株式会社 | 複素環化合物 |
| MX358346B (es) | 2014-04-04 | 2018-08-15 | Syros Pharmaceuticals Inc | Inhibidores de la quinasa dependiente de ciclina 7 (cdk7). |
| WO2020013116A1 (ja) * | 2018-07-10 | 2020-01-16 | 京都薬品工業株式会社 | Ｐｔｐ－１ｂ阻害剤およびその用途 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6051189A (ja) | 1983-08-30 | 1985-03-22 | Sankyo Co Ltd | チアゾリジン誘導体およびその製造法 |
| AR240698A1 (es) | 1985-01-19 | 1990-09-28 | Takeda Chemical Industries Ltd | Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales |
| ATE186724T1 (de) | 1987-09-04 | 1999-12-15 | Beecham Group Plc | Substituierte thiazolidindionderivate |
| US5246943A (en) | 1992-05-19 | 1993-09-21 | Warner-Lambert Company | Substituted 1,2,3,4-tetahydroisoquinolines with angiotensin II receptor antagonist properties |
| GB9604242D0 (en) | 1996-02-28 | 1996-05-01 | Glaxo Wellcome Inc | Chemical compounds |
| ATE277907T1 (de) * | 1996-07-01 | 2004-10-15 | Lilly Co Eli | Blutzuckersenkende und lipidsenkende verbindungen |
| AU3719997A (en) | 1996-07-01 | 1998-01-21 | Eli Lilly And Company | Hypoglycemic and hypolipidemic compounds |
| GB9817118D0 (en) * | 1998-08-07 | 1998-10-07 | Glaxo Group Ltd | Pharmaceutical compounds |
| RU2256661C2 (ru) * | 1999-12-03 | 2005-07-20 | Киото Фармасьютикал Индастриз, Лтд. | Производные тетрагидроизохинолина и их соли и фармацевтическая композиция на их основе |
| US20020037897A1 (en) | 2000-08-07 | 2002-03-28 | 3-Dimensional Pharmaceuticals, Inc. | Tetrahydroisoquinoline-3-carboxylic acid alkoxyguanidines as integrin antagonists |
| KR100898358B1 (ko) | 2001-05-29 | 2009-05-20 | 교토 야쿠힝 고교 가부시키가이샤 | 신규 복소환 화합물 및 그 의약 용도 |
-
2002
- 2002-05-27 MX MXPA03010867A patent/MXPA03010867A/es active IP Right Grant
- 2002-05-27 CA CA002448639A patent/CA2448639A1/en not_active Abandoned
- 2002-05-27 PL PL02367676A patent/PL367676A1/xx not_active IP Right Cessation
- 2002-05-27 HU HU0400023A patent/HUP0400023A2/hu unknown
- 2002-05-27 IL IL15908402A patent/IL159084A0/xx unknown
- 2002-05-27 YU YU94203A patent/YU94203A/sh unknown
- 2002-05-27 BR BR0209735-4A patent/BR0209735A/pt not_active IP Right Cessation
- 2002-05-27 JP JP2003500083A patent/JP4279137B2/ja not_active Expired - Fee Related
- 2002-05-27 KR KR1020037015518A patent/KR100874677B1/ko not_active IP Right Cessation
- 2002-05-27 EP EP02774071A patent/EP1398313A4/en not_active Withdrawn
- 2002-05-27 NZ NZ530313A patent/NZ530313A/en unknown
- 2002-05-27 WO PCT/JP2002/005098 patent/WO2002096904A1/ja active IP Right Grant
- 2002-05-27 AU AU2002308891A patent/AU2002308891B2/en not_active Ceased
- 2002-05-27 CN CNA028109627A patent/CN1522253A/zh active Pending
- 2002-05-27 RU RU2003137576/04A patent/RU2287529C2/ru not_active IP Right Cessation
- 2002-05-27 US US10/478,863 patent/US6872732B2/en not_active Expired - Fee Related
- 2002-05-27 CZ CZ20033415A patent/CZ20033415A3/cs unknown
- 2002-05-28 TW TW091111323A patent/TWI243172B/zh not_active IP Right Cessation
- 2002-05-29 AR ARP020102003A patent/AR036037A1/es unknown
-
2003
- 2003-11-28 NO NO20035332A patent/NO326559B1/no unknown
- 2003-12-08 ZA ZA200309513A patent/ZA200309513B/xx unknown
- 2003-12-29 CO CO03112805A patent/CO5540322A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO326559B1 (no) | 2009-01-12 |
| EP1398313A4 (en) | 2005-11-16 |
| EP1398313A1 (en) | 2004-03-17 |
| HUP0400023A2 (hu) | 2004-04-28 |
| CA2448639A1 (en) | 2002-12-05 |
| ZA200309513B (en) | 2004-12-08 |
| US20040180924A1 (en) | 2004-09-16 |
| NO20035332D0 (no) | 2003-11-28 |
| AU2002308891B2 (en) | 2007-09-06 |
| MXPA03010867A (es) | 2004-02-27 |
| CZ20033415A3 (cs) | 2004-06-16 |
| JPWO2002096904A1 (ja) | 2004-09-09 |
| JP4279137B2 (ja) | 2009-06-17 |
| AR036037A1 (es) | 2004-08-04 |
| KR100874677B1 (ko) | 2008-12-18 |
| NZ530313A (en) | 2005-06-24 |
| CO5540322A2 (es) | 2005-07-29 |
| TWI243172B (en) | 2005-11-11 |
| US6872732B2 (en) | 2005-03-29 |
| BR0209735A (pt) | 2004-07-27 |
| WO2002096904A1 (fr) | 2002-12-05 |
| RU2287529C2 (ru) | 2006-11-20 |
| KR20040004663A (ko) | 2004-01-13 |
| RU2003137576A (ru) | 2005-05-20 |
| YU94203A (sh) | 2006-08-17 |
| CN1522253A (zh) | 2004-08-18 |
| PL367676A1 (en) | 2005-03-07 |
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