IL158448A0 - Heterocyclylalkoxy- alkylthio-and-alkylaminobenzazole derivatives as 5-hydroxytryptamine-6 ligands - Google Patents
Heterocyclylalkoxy- alkylthio-and-alkylaminobenzazole derivatives as 5-hydroxytryptamine-6 ligandsInfo
- Publication number
- IL158448A0 IL158448A0 IL15844802A IL15844802A IL158448A0 IL 158448 A0 IL158448 A0 IL 158448A0 IL 15844802 A IL15844802 A IL 15844802A IL 15844802 A IL15844802 A IL 15844802A IL 158448 A0 IL158448 A0 IL 158448A0
- Authority
- IL
- Israel
- Prior art keywords
- alkylaminobenzazole
- heterocyclylalkoxy
- hydroxytryptamine
- alkylthio
- ligands
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28564401P | 2001-04-20 | 2001-04-20 | |
| PCT/US2002/012512 WO2002085853A2 (en) | 2001-04-20 | 2002-04-19 | Heterocyclylalkoxy-, -alkylthio- and -alkylaminobenzazole derivatives as 5-hydroxytryptamine-6 ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL158448A0 true IL158448A0 (en) | 2004-05-12 |
Family
ID=23095117
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15844802A IL158448A0 (en) | 2001-04-20 | 2002-04-19 | Heterocyclylalkoxy- alkylthio-and-alkylaminobenzazole derivatives as 5-hydroxytryptamine-6 ligands |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US6831094B2 (no) |
| EP (1) | EP1392682A2 (no) |
| JP (1) | JP2004526781A (no) |
| KR (1) | KR20030088507A (no) |
| CN (1) | CN1293073C (no) |
| AR (1) | AR034588A1 (no) |
| AU (1) | AU2002309585B2 (no) |
| BR (1) | BR0209047A (no) |
| CA (1) | CA2444036A1 (no) |
| EA (1) | EA200301143A1 (no) |
| HU (1) | HUP0303801A2 (no) |
| IL (1) | IL158448A0 (no) |
| MX (1) | MXPA03009490A (no) |
| NO (1) | NO20034647L (no) |
| PL (1) | PL366639A1 (no) |
| WO (1) | WO2002085853A2 (no) |
| ZA (1) | ZA200309009B (no) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2323927C2 (ru) * | 2002-06-05 | 2008-05-10 | Ф.Хоффманн-Ля Рош Аг | Производные 1-сульфонил-4-аминоалкоксииндола и фармацевтическая композиция, обладающая активностью модулятора 5-нт6 рецептора |
| JP4339795B2 (ja) * | 2002-12-03 | 2009-10-07 | エフ．ホフマン−ラ ロシュ アーゲー | Ｃｎｓ障害の治療のための５−ｈｔ６レセプターリガンドとしてのアミノアルコキシインドール |
| TW200505904A (en) * | 2003-02-14 | 2005-02-16 | Wyeth Corp | Heterocyclyl-3-sulfonylindazoles as 5-hydroxytryptamine-6 ligands |
| SE0302760D0 (sv) * | 2003-10-20 | 2003-10-20 | Biovitrum Ab | New compounds |
| BRPI0614341A2 (pt) * | 2005-08-15 | 2011-03-29 | Wyeth Corp | composto; método para o tratamento de um distúrbio do sistema nervoso central relacionado com o receptor de 5-ht6 ou afetado por ele em um paciente que deste necessite; composição farmacêutica; e processo |
| UA94053C2 (ru) * | 2005-08-15 | 2011-04-11 | Уайет | Замещенные производные 3-сульфонилиндазола в качестве лигандов гидрокситриптамина-6 |
| WO2007117413A1 (en) * | 2006-04-05 | 2007-10-18 | Wyeth | Sulfonyl-3-heterocyclylindazole derivatives as 5-hydroxytryptamine-6 ligands |
| WO2007120596A1 (en) * | 2006-04-12 | 2007-10-25 | Wyeth | DIHYDRO[1,4]DIOXINO[2,3-e]INDAZOLE DERIVATIVES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS |
| JP2009538910A (ja) * | 2006-06-01 | 2009-11-12 | ワイス | ５−ヒドロキシトリプタミン−６リガンドとしての１−スルホニルインダゾリルアミン誘導体および１−スルホニルインダゾリルアミド誘導体 |
| WO2009006267A2 (en) * | 2007-06-28 | 2009-01-08 | Wyeth | N'-(2-halobenzylidene)sulfonylhydrazides as intermediates in the manufacture of arylsulfonylindazoles |
| JP2013526542A (ja) | 2010-05-12 | 2013-06-24 | アッヴィ・インコーポレイテッド | キナーゼのインダゾール阻害薬 |
| LT2624696T (lt) | 2010-10-06 | 2017-03-10 | Glaxosmithkline Llc | Benzimidazolo deriniai kaip pi3 kinazės inhibitoriai |
| EP3083588B1 (en) | 2013-12-20 | 2020-12-09 | Sunshine Lake Pharma Co., Ltd. | Aromatic heterocyclic compounds and their application in pharmaceuticals |
| US9974785B2 (en) | 2014-07-08 | 2018-05-22 | Sunshine Lake Pharma Co., Ltd. | Aromatic heterocyclic derivatives and pharmaceutical applications thereof |
| UA125318C2 (uk) | 2017-08-01 | 2022-02-16 | Тереванс Байофарма Ар Енд Ді Айпі, Елелсі | Піразоло- і триазолобіциклічні сполуки як інгібітори jak-кінази |
| CN113498352A (zh) | 2019-01-23 | 2021-10-12 | 施万生物制药研发Ip有限责任公司 | 作为jak抑制剂的咪唑并[1,5-a]吡啶、1,2,4-三唑并[4,3-a]吡啶和咪唑并[1,5-a]吡嗪 |
| EP4065578A1 (en) | 2019-11-26 | 2022-10-05 | Theravance Biopharma R&D IP, LLC | Fused pyrimidine pyridinone compounds as jak inhibitors |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5274097A (en) * | 1988-04-19 | 1993-12-28 | Bayer Aktiengesellschaft | 1,3-disubstituted pyrrolidines |
| DE3835291A1 (de) | 1988-04-19 | 1989-11-02 | Bayer Ag | 1,3-disubstituierte pyrrolidine |
| GB9103862D0 (en) * | 1991-02-25 | 1991-04-10 | Glaxo Group Ltd | Chemical compounds |
| TW288010B (no) * | 1992-03-05 | 1996-10-11 | Pfizer | |
| WO1995003298A1 (en) | 1993-07-19 | 1995-02-02 | Fujisawa Pharmaceutical Co., Ltd. | BENZIMIDAZOLE DERIVATIVES USEFUL AS DOPAMINE RECEPTOR ANTAGONIST, 5-HT RECEPTOR AGONIST OR α1 RECEPTOR ANTAGONIST |
| US5578716A (en) * | 1993-12-01 | 1996-11-26 | Mcgill University | DNA methyltransferase antisense oligonucleotides |
| JPH0940646A (ja) | 1995-07-27 | 1997-02-10 | Yamanouchi Pharmaceut Co Ltd | ベンゼン縮合環誘導体又はその塩 |
| GB9523462D0 (en) | 1995-11-16 | 1996-01-17 | Merck Sharp & Dohme | Therapeutic agents |
| WO1998050346A2 (en) * | 1997-04-18 | 1998-11-12 | Smithkline Beecham Plc | Acetamide and urea derivatives, process for their preparation and their use in the treatment of cns disorders |
| WO2001005758A2 (en) | 1999-07-15 | 2001-01-25 | Nps Allelix Corp. | Indoles and indazoles for the treatment of migraine |
| EA200300717A1 (ru) * | 2000-12-22 | 2003-12-25 | Уайт | Гетероциклилиндазольные и -азаиндазольные соединения в качестве 5-гидрокситриптамин-6-лигандов |
| TW593278B (en) * | 2001-01-23 | 2004-06-21 | Wyeth Corp | 1-aryl-or 1-alkylsulfonylbenzazole derivatives as 5-hydroxytryptamine-6 ligands |
| TW200401641A (en) * | 2002-07-18 | 2004-02-01 | Wyeth Corp | 1-Heterocyclylalkyl-3-sulfonylindole or-indazole derivatives as 5-hydroxytryptamine-6 ligands |
| TW200505904A (en) * | 2003-02-14 | 2005-02-16 | Wyeth Corp | Heterocyclyl-3-sulfonylindazoles as 5-hydroxytryptamine-6 ligands |
-
2002
- 2002-04-19 MX MXPA03009490A patent/MXPA03009490A/es active IP Right Grant
- 2002-04-19 AU AU2002309585A patent/AU2002309585B2/en not_active Expired - Fee Related
- 2002-04-19 WO PCT/US2002/012512 patent/WO2002085853A2/en active Application Filing
- 2002-04-19 HU HU0303801A patent/HUP0303801A2/hu unknown
- 2002-04-19 PL PL02366639A patent/PL366639A1/xx unknown
- 2002-04-19 JP JP2002583380A patent/JP2004526781A/ja active Pending
- 2002-04-19 EA EA200301143A patent/EA200301143A1/ru unknown
- 2002-04-19 US US10/126,805 patent/US6831094B2/en not_active Expired - Fee Related
- 2002-04-19 CN CNB028123409A patent/CN1293073C/zh not_active Expired - Fee Related
- 2002-04-19 AR ARP020101443A patent/AR034588A1/es not_active Application Discontinuation
- 2002-04-19 KR KR10-2003-7013584A patent/KR20030088507A/ko not_active Application Discontinuation
- 2002-04-19 EP EP02736592A patent/EP1392682A2/en not_active Withdrawn
- 2002-04-19 BR BR0209047-3A patent/BR0209047A/pt not_active IP Right Cessation
- 2002-04-19 CA CA002444036A patent/CA2444036A1/en not_active Abandoned
- 2002-04-19 IL IL15844802A patent/IL158448A0/xx unknown
-
2003
- 2003-10-17 NO NO20034647A patent/NO20034647L/no not_active Application Discontinuation
- 2003-11-19 ZA ZA200309009A patent/ZA200309009B/en unknown
-
2004
- 2004-09-24 US US10/949,061 patent/US20050065185A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| NO20034647L (no) | 2003-11-20 |
| BR0209047A (pt) | 2004-08-10 |
| NO20034647D0 (no) | 2003-10-17 |
| CA2444036A1 (en) | 2002-10-31 |
| EP1392682A2 (en) | 2004-03-03 |
| KR20030088507A (ko) | 2003-11-19 |
| PL366639A1 (en) | 2005-02-07 |
| AR034588A1 (es) | 2004-03-03 |
| WO2002085853A3 (en) | 2002-12-19 |
| US20030078286A1 (en) | 2003-04-24 |
| US6831094B2 (en) | 2004-12-14 |
| EA200301143A1 (ru) | 2004-02-26 |
| ZA200309009B (en) | 2005-02-21 |
| US20050065185A1 (en) | 2005-03-24 |
| MXPA03009490A (es) | 2004-02-12 |
| JP2004526781A (ja) | 2004-09-02 |
| AU2002309585B2 (en) | 2008-01-31 |
| CN1293073C (zh) | 2007-01-03 |
| HUP0303801A2 (hu) | 2004-03-01 |
| WO2002085853A2 (en) | 2002-10-31 |
| CN1518548A (zh) | 2004-08-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL157059A0 (en) | 1-aryl-or 1-alkylsulfonylbenzazole derivatives as 5-hydroxytryptamine-6 ligands | |
| IL158445A0 (en) | Heterocyclyloxy-, -thioxy-and-aminobenzazole derivatives as 5-hydroxytryptamine-6 ligands | |
| PL370890A1 (en) | Azaindolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands | |
| ZA200500437B (en) | 1-heterocyclyalkyl-3-sulfonazaindole or -azaindazole derivatives as 5-hydroxytryptamine-6 ligands | |
| AU2005102A (en) | 1-aryl- or 1-alkylsulfonyl-heterocyclylbenzazoles as 5-hydroxytryptamine-6 ligands | |
| ZA200500435B (en) | 1-heterocyclyalkyl-3-sulfonylindole or -indazole derivatves as 5-hydroxytryptamine-6 ligands | |
| HK1066218A1 (en) | Qunazoline derivatives as antitumor agents | |
| IL162243A0 (en) | Indolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands | |
| ZA200506416B (en) | Heterocyclyl-3-sulfonylindazoles as 5-hydroxytryptamine-6 ligands | |
| IL156517A0 (en) | Heterocyclindazole and azaindazole compounds as 5-hydroxytryptamine-6 ligands | |
| HK1068608A1 (en) | 3-Substituted-4-pyrimidone derivatives | |
| IL156518A0 (en) | Heteocyclylalkylindole or-azaindole compounds as 5-hydroxytryptamine-6 ligands | |
| IL158448A0 (en) | Heterocyclylalkoxy- alkylthio-and-alkylaminobenzazole derivatives as 5-hydroxytryptamine-6 ligands | |
| HK1068607A1 (en) | Phenylalkyloxy-phenyl derivatives | |
| HUP0303186A3 (en) | 4-aminobenzopyran derivatives | |
| HUP0401949A3 (en) | 4-imidazolin-2-one derivatives | |
| HUP0500026A3 (en) | N-heteroarylnicotinamide derivatives | |
| AU2003209114A1 (en) | Pyrrolylalkylidene-hydrazinecarboximidamide derivatives as 5-hydroxytryptamine-6 ligands | |
| EP1364954A4 (en) | Dicarba closo DODECARBORANDERIVATE | |
| GB0115841D0 (en) | Ligand | |
| AU2002334722A1 (en) | Chroman derivatives as 5-hydroxytryptamine-6 ligands | |
| SI1427709T1 (sl) | 3-substituirani-4-pirimidonski derivati |