IL158083A0 - A PHARMACEUTICAL COMPOSITION CONTAINING AN Eg5 PROTEIN INHIBITOR - Google Patents
A PHARMACEUTICAL COMPOSITION CONTAINING AN Eg5 PROTEIN INHIBITORInfo
- Publication number
- IL158083A0 IL158083A0 IL15808302A IL15808302A IL158083A0 IL 158083 A0 IL158083 A0 IL 158083A0 IL 15808302 A IL15808302 A IL 15808302A IL 15808302 A IL15808302 A IL 15808302A IL 158083 A0 IL158083 A0 IL 158083A0
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceutical composition
- composition containing
- protein inhibitor
- inhibitor
- protein
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 229940121649 protein inhibitor Drugs 0.000 title 1
- 239000012268 protein inhibitor Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27995601P | 2001-03-29 | 2001-03-29 | |
| US28036601P | 2001-03-30 | 2001-03-30 | |
| PCT/US2002/009817 WO2002078639A2 (en) | 2001-03-29 | 2002-03-28 | A method of treating proliferative diseases using eg5 inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL158083A0 true IL158083A0 (en) | 2004-03-28 |
Family
ID=26959985
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15808302A IL158083A0 (en) | 2001-03-29 | 2002-03-28 | A PHARMACEUTICAL COMPOSITION CONTAINING AN Eg5 PROTEIN INHIBITOR |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20020165240A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1372657A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2005506298A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2442455A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL158083A0 (cg-RX-API-DMAC7.html) |
| MX (1) | MXPA03008691A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2002078639A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040009156A1 (en) * | 2001-10-12 | 2004-01-15 | Christoph Reinhard | Antisense therapy using oligonucleotides that target human kinesin genes for treatment of cancer |
| DK1847534T3 (da) * | 2001-12-11 | 2011-08-29 | Kyowa Hakko Kirin Co Ltd | Thiadiazolin-derivater til behandling af kræft |
| US7199107B2 (en) | 2002-05-23 | 2007-04-03 | Isis Pharmaceuticals, Inc. | Antisense modulation of kinesin-like 1 expression |
| CN1774428B (zh) * | 2003-04-18 | 2010-06-16 | 协和发酵麒麟株式会社 | M期驱动蛋白抑制剂 |
| JPWO2004111024A1 (ja) * | 2003-06-10 | 2006-07-20 | 協和醗酵工業株式会社 | チアジアゾリン誘導体 |
| WO2005007124A2 (en) | 2003-07-23 | 2005-01-27 | Bristol-Myers Squibb Company | Substituted dihydropyrimidine inhibitors of calcium channel function |
| US7166603B2 (en) | 2003-07-23 | 2007-01-23 | Bristol-Myers Squibb Co. | Dihydropyrimidone inhibitors of calcium channel function |
| US20050158320A1 (en) * | 2003-11-12 | 2005-07-21 | Nichols M. J. | Combinations for the treatment of proliferative diseases |
| US20050100508A1 (en) * | 2003-11-12 | 2005-05-12 | Nichols M. J. | Methods for identifying drug combinations for the treatment of proliferative diseases |
| US7662581B1 (en) | 2003-12-18 | 2010-02-16 | Novartis Vaccines And Diagnostics, Inc. | Eg5 co-crystals |
| ES2315727T3 (es) * | 2003-12-20 | 2009-04-01 | Merck Patent Gmbh | Derivados de tetrahidroquinolina 2-(hetero-)aril-substituidos. |
| ES2360073T3 (es) * | 2004-03-23 | 2011-05-31 | Oncotherapy Science, Inc. | Método para diagnosticar cáncer de pulmón de células no pequeñas. |
| DE102004021637A1 (de) * | 2004-05-03 | 2005-12-01 | Merck Patent Gmbh | Dihydrobenzothiophene |
| BRPI0514390A (pt) | 2004-08-18 | 2008-06-10 | Astrazeneca Ab | enanciÈmero de um composto ou um sal farmacêuticamente aceitável ou um éster hidrolisável in vivo do mesmo, uso do mesmo, métodos para o tratamento de cáncer, para produzir um efeito inibidor de eg5 em um animal de sangue quente e para tratar doenças, e, composição farmacêutica |
| WO2006074293A2 (en) * | 2005-01-07 | 2006-07-13 | President And Fellows Of Harvard College | Bicyclic dihydropyrimidines as eg5 inhibitors |
| JPWO2006101103A1 (ja) * | 2005-03-22 | 2008-09-04 | 協和醗酵工業株式会社 | 造血器腫瘍治療剤 |
| EP1867640A4 (en) * | 2005-03-22 | 2010-07-14 | Kyowa Hakko Kirin Co Ltd | MEANS FOR TREATING SOLID TUMORS |
| WO2006137490A1 (ja) * | 2005-06-24 | 2006-12-28 | Kyowa Hakko Kogyo Co., Ltd. | 再狭窄治療剤 |
| DE102006002065B4 (de) * | 2006-01-16 | 2007-11-29 | Infineon Technologies Austria Ag | Kompensationsbauelement mit reduziertem und einstellbarem Einschaltwiderstand |
| WO2007107543A1 (en) | 2006-03-22 | 2007-09-27 | Janssen Pharmaceutica N.V. | Inhibitors of the interaction between mdm2 and p53 |
| KR20110022000A (ko) | 2008-05-30 | 2011-03-04 | 다나-파버 캔서 인스티튜트 인크. | 감수분열 키네신-연관된 질환의 치료 방법 |
| JP2013528601A (ja) | 2010-05-20 | 2013-07-11 | アストラゼネカ・アクチエボラーグ | アリール置換オレフィン系アミンの新規な製造方法 |
| RU2427373C1 (ru) * | 2010-11-08 | 2011-08-27 | Виктор Вениаминович Тец | Средство для индукции эндогенного интерферона |
| CN113135859B (zh) * | 2021-04-26 | 2022-08-26 | 安徽省庆云医药股份有限公司 | 一种绿色合成瑞舒伐他汀钙中间体的方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2658804A1 (de) * | 1976-12-24 | 1978-07-06 | Bayer Ag | Kreislaufbeeinflussende mittel |
| EP0330470A3 (en) * | 1988-02-24 | 1992-01-02 | Ajinomoto Co., Inc. | 1,4-dihydropyridine derivatives useful against tumour cells |
| US5536724A (en) * | 1992-03-03 | 1996-07-16 | Sri International | Antiinflammatory and antineoplastic 5-deazaaminopterins and 5,10-dideazaaminopterins |
| US5767131A (en) * | 1993-04-05 | 1998-06-16 | Synaptic Pharmaceutical Corporation | Dihydropyridines and new uses thereof |
-
2002
- 2002-03-28 CA CA002442455A patent/CA2442455A1/en not_active Abandoned
- 2002-03-28 IL IL15808302A patent/IL158083A0/xx unknown
- 2002-03-28 US US10/108,403 patent/US20020165240A1/en not_active Abandoned
- 2002-03-28 WO PCT/US2002/009817 patent/WO2002078639A2/en not_active Ceased
- 2002-03-28 EP EP02717741A patent/EP1372657A4/en not_active Withdrawn
- 2002-03-28 JP JP2002576907A patent/JP2005506298A/ja not_active Withdrawn
- 2002-03-28 MX MXPA03008691A patent/MXPA03008691A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002078639A2 (en) | 2002-10-10 |
| US20020165240A1 (en) | 2002-11-07 |
| WO2002078639A3 (en) | 2003-04-10 |
| JP2005506298A (ja) | 2005-03-03 |
| EP1372657A4 (en) | 2005-11-09 |
| MXPA03008691A (es) | 2003-12-12 |
| EP1372657A2 (en) | 2004-01-02 |
| CA2442455A1 (en) | 2002-10-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL158083A0 (en) | A PHARMACEUTICAL COMPOSITION CONTAINING AN Eg5 PROTEIN INHIBITOR | |
| IL209444A0 (en) | O-desmethyl-venlafaxine succinate salts and pharmaceutical compositions containing them | |
| HUP0303325A3 (en) | Pharmaceutical salts and pharmaceutical compositions containing them | |
| EP1450824A4 (en) | PHARMACEUTICAL COMPOSITION | |
| GB0125445D0 (en) | Protease Inhibitors | |
| PL360967A1 (en) | Pharmaceutical compound containing donepezyl hydrochloride | |
| HUP0400974A3 (en) | Peptide-based compounds and pharmaceutical compositions containing them | |
| AU2001296961A1 (en) | 17-beta-hydroxysteroid dehydrogenase-ii inhibitors | |
| AU2003276549A8 (en) | Pharmaceutical compositions containing a biguanide-glitazone combination | |
| HUP0303163A3 (en) | Tramadol-based pharmaceutical composition | |
| GB0117057D0 (en) | Pharmaceutical composition | |
| AU2002230385A1 (en) | Peptide deformylase inhibitors | |
| GB0129117D0 (en) | Pharmaceutical composition | |
| EG24516A (en) | Peptide deformylase inhibitors | |
| EP1408896A4 (en) | PHARMACEUTICAL COMPOSITION | |
| GB0116107D0 (en) | Pharmaceutical composition | |
| GB0127805D0 (en) | Pharmaceutical composition | |
| PL370037A1 (en) | Pharmaceutical composition | |
| IL164755A0 (en) | Pharmaceutical composition containing a reversibleprotein pump inhibitor | |
| EP1401453A4 (en) | PROTEASE INHIBITORS | |
| EP1383729A4 (en) | DEFORMYLASE PEPTIDE INHIBITORS | |
| AU2002255634A1 (en) | Peptide deformylase inhibitors | |
| IL164756A0 (en) | Pharmaceutical compositions containing protein pump inhibitors | |
| IL157411A0 (en) | Pharmaceutical composition | |
| AU2002342940A8 (en) | New pharmaceutical compounds |