IL157694A0 - Method of determining dihydropyrimidine dehydrogenase gene expression - Google Patents

Method of determining dihydropyrimidine dehydrogenase gene expression

Info

Publication number
IL157694A0
IL157694A0 IL15769402A IL15769402A IL157694A0 IL 157694 A0 IL157694 A0 IL 157694A0 IL 15769402 A IL15769402 A IL 15769402A IL 15769402 A IL15769402 A IL 15769402A IL 157694 A0 IL157694 A0 IL 157694A0
Authority
IL
Israel
Prior art keywords
gene expression
dehydrogenase gene
dihydropyrimidine dehydrogenase
determining
determining dihydropyrimidine
Prior art date
Application number
IL15769402A
Other languages
English (en)
Original Assignee
Response Genetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/796,807 external-priority patent/US6956111B2/en
Application filed by Response Genetics Inc filed Critical Response Genetics Inc
Publication of IL157694A0 publication Critical patent/IL157694A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
IL15769402A 2001-03-02 2002-02-22 Method of determining dihydropyrimidine dehydrogenase gene expression IL157694A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US09/796,807 US6956111B2 (en) 2001-03-02 2001-03-02 Method of determining dihydropyrimidine dehydrogenase gene expression
US09/842,111 US6905821B2 (en) 2001-03-02 2001-04-26 Method of determining Dihydropyrimidine dehydrogenase gene expression
US09/879,217 US7005278B2 (en) 2001-03-02 2001-06-13 Method of determining dihydropyrimidine dehydrogenase gene expression
PCT/US2002/005221 WO2002070750A2 (en) 2001-03-02 2002-02-22 Method of determining dihydropyrimidine dehydrogenase gene expression

Publications (1)

Publication Number Publication Date
IL157694A0 true IL157694A0 (en) 2004-03-28

Family

ID=27419931

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15769402A IL157694A0 (en) 2001-03-02 2002-02-22 Method of determining dihydropyrimidine dehydrogenase gene expression

Country Status (15)

Country Link
US (1) US7005278B2 (zh)
EP (1) EP1409723B1 (zh)
JP (1) JP2005508603A (zh)
CN (1) CN1250744C (zh)
AR (1) AR032917A1 (zh)
AT (1) ATE339521T1 (zh)
AU (1) AU2002238115B2 (zh)
CA (1) CA2439313C (zh)
DE (1) DE60214725T2 (zh)
HK (1) HK1068375A1 (zh)
IL (1) IL157694A0 (zh)
MX (1) MXPA03007884A (zh)
NZ (1) NZ528374A (zh)
TW (1) TWI274076B (zh)
WO (1) WO2002070750A2 (zh)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020142328A1 (en) 2000-12-01 2002-10-03 Danenberg Kathleen D. Method of determining a chemotherapeutic regimen by assaying gene expression in primary tumors
ES2279266T3 (es) * 2003-08-28 2007-08-16 F. Hoffmann-La Roche Ag Correlacion del cociente de los niveles de expresion del mrna de la timidina fosforilasa y la dihidropirimidina dehidrogenasa en el cancer colorrectal con supervivencia libre de enfermedad en pacientes tratados con 5-fu.
KR20200058588A (ko) * 2005-01-21 2020-05-27 제넨테크, 인크. Ｈｅｒ 항체의 고정 용량 투여법
ZA200707078B (en) 2005-02-23 2008-11-26 Genentech Inc Extending time to disease progression or survival in cancer patients
JP2006316040A (ja) 2005-05-13 2006-11-24 Genentech Inc Ｈｅｒｃｅｐｔｉｎ（登録商標）補助療法
JP4880621B2 (ja) * 2006-01-25 2012-02-22 大鵬薬品工業株式会社 ５−フルオロウラシル系抗癌剤に対する感受性を予測する方法
DK2132573T3 (da) 2007-03-02 2014-07-14 Genentech Inc Forudsigelse af respons på en her-dimeriseringsinhibitor på basis af lav her3-ekspression
US9551033B2 (en) 2007-06-08 2017-01-24 Genentech, Inc. Gene expression markers of tumor resistance to HER2 inhibitor treatment
ES2583377T3 (es) 2007-06-08 2016-09-20 Genentech, Inc. Marcadores de expresión génica de la resistencia tumoral al tratamiento con inhibidor de HER2
KR20100012056A (ko) 2007-06-22 2010-02-04 리스판스 지네틱스, 인크. 고정 표본에서 긴 단편 ｒｎａ를 분리하는 방법
BRPI0812682A2 (pt) 2008-06-16 2010-06-22 Genentech Inc tratamento de cáncer de mama metastático
RU2504553C2 (ru) 2009-03-20 2014-01-20 Дженентек, Инк. Антитела к her
EP2435071A1 (en) 2009-05-29 2012-04-04 F. Hoffmann-La Roche AG Modulators for her2 signaling in her2 expressing patients with gastric cancer
US8079170B2 (en) * 2009-08-28 2011-12-20 Loftin Thomas E Gun barrel cleaning apparatus and method
AU2011218125A1 (en) 2010-02-18 2012-07-19 Genentech, Inc. Neuregulin antagonists and use thereof in treating cancer
WO2011146568A1 (en) 2010-05-19 2011-11-24 Genentech, Inc. Predicting response to a her inhibitor
EP2643353A1 (en) 2010-11-24 2013-10-02 Novartis AG Multispecific molecules
WO2012085111A1 (en) 2010-12-23 2012-06-28 F. Hoffmann-La Roche Ag Polypeptide-polynucleotide-complex and its use in targeted effector moiety delivery
JP2014526891A (ja) 2011-08-17 2014-10-09 ジェネンテック， インコーポレイテッド ニューレグリン抗体とその使用
WO2013063229A1 (en) 2011-10-25 2013-05-02 The Regents Of The University Of Michigan Her2 targeting agent treatment in non-her2-amplified cancers having her2 expressing cancer stem cells
WO2013081645A2 (en) 2011-11-30 2013-06-06 Genentech, Inc. Erbb3 mutations in cancer
EP2788500A1 (en) 2011-12-09 2014-10-15 F.Hoffmann-La Roche Ag Identification of non-responders to her2 inhibitors
US20130259867A1 (en) 2012-03-27 2013-10-03 Genentech, Inc. Diagnosis and treatments relating to her3 inhibitors
CN104813168B (zh) 2012-11-30 2017-10-20 霍夫曼-拉罗奇有限公司 需要pd‑l1抑制剂综合疗法的患者的鉴定
US20190151346A1 (en) 2016-05-10 2019-05-23 INSERM (Institute National de la Santé et de la Recherche Médicale) Combinations therapies for the treatment of cancer

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4830969A (en) * 1981-08-31 1989-05-16 The Research Foundation Of State University Of New York Process for the rapid and simple isolation of nucleic acids
US4843155A (en) * 1987-11-19 1989-06-27 Piotr Chomczynski Product and process for isolating RNA
US5128247A (en) * 1989-08-14 1992-07-07 Board Of Regents, The University Of Texas System Methods for isolation of nucleic acids from eukaryotic and prokaryotic sources
US5284940A (en) * 1990-11-14 1994-02-08 Hri Research, Inc. Preparation for nucleic acid samples
US5654179A (en) * 1990-11-14 1997-08-05 Hri Research, Inc. Nucleic acid preparation methods
US5620852A (en) * 1990-11-14 1997-04-15 Hri Research, Inc. Nucleic acid preparation methods
US5346994A (en) * 1992-01-28 1994-09-13 Piotr Chomczynski Shelf-stable product and process for isolating RNA, DNA and proteins
US5502166A (en) * 1992-02-26 1996-03-26 Mitsubishi Chemical Corporation NMDH receptor proteins and genes encoding the same
AU6230594A (en) * 1993-02-01 1994-08-29 University Of Iowa Research Foundation, The Quartenary amine surfactants and methods of using same in isolation of rna
US5637687A (en) * 1993-08-31 1997-06-10 Wiggins; James C. Methods and compositions for isolating nucleic acids
AU2289495A (en) 1994-04-13 1995-11-10 Uab Research Foundation, The Dihydropyrimidine dehydrogenase compositions and methods of use
US5643767A (en) * 1994-05-02 1997-07-01 The Rockefeller University Process for isolating cellular components
CA2153215A1 (en) * 1994-07-06 1996-01-07 Lu Wang Treatment of paraffin embedded tissue for gene analysis
US5856454A (en) * 1994-09-12 1999-01-05 The United States Of America As Represented By The Department Of Health And Human Services CDNA for human and pig dihydropyrimidine dehydrogenase
US5707802A (en) * 1995-01-13 1998-01-13 Ciba Corning Diagnostics Corp. Nucleic acid probes for the detection and identification of fungi
US5777099A (en) * 1995-02-24 1998-07-07 Biotecx Laboratories, Inc. RNA separation
US5945515A (en) * 1995-07-31 1999-08-31 Chomczynski; Piotr Product and process for isolating DNA, RNA and proteins
DE29601618U1 (de) * 1996-01-31 1996-07-04 Invitek Gmbh Vorrichtung zur gleichzeitigen multiplen Isolierung
EP0791654A1 (en) * 1996-02-21 1997-08-27 Jürgen A. Dr. Richt Polypeptides corresponding to the amino acid sequences of proteins p57 or p9.5 of Borna disease virus, nucleic acid fragments coding therefore and their use for diagnostic and immunization purposes
WO1997035034A1 (en) 1996-03-20 1997-09-25 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Methods and compositions for detecting dihydropyrimidine dehydrogenase splicing mutations
CA2253937A1 (en) * 1996-05-10 1997-11-20 Phylomed Corporation Methods for oxidizing disulfide bonds using ozone
AU6764398A (en) 1997-03-20 1998-10-12 Variagenics, Inc. Target genes for allele-specific drugs
DE19837391A1 (de) 1997-08-22 1999-02-25 Hoffmann La Roche Immunologische Materialien und Verfahren zum Nachweis von Dihydropyrimidindehydrogenase
US5952202A (en) * 1998-03-26 1999-09-14 The Perkin Elmer Corporation Methods using exogenous, internal controls and analogue blocks during nucleic acid amplification
CN1488002A (zh) * 2000-12-01 2004-04-07 ��˹��ŵ�� 测定表皮生长因子受体和HER2-neu的基因表达及其水平与存活率之间相关性的方法
WO2002044423A2 (en) 2000-12-01 2002-06-06 Response Genetics, Inc. Method of determining a chemotherapeutic regimen by assaying gene expression in primary tumors

Also Published As

Publication number Publication date
EP1409723A2 (en) 2004-04-21
CA2439313A1 (en) 2002-09-12
TWI274076B (en) 2007-02-21
WO2002070750A3 (en) 2004-02-19
US7005278B2 (en) 2006-02-28
DE60214725D1 (de) 2006-10-26
NZ528374A (en) 2008-01-31
CN1518603A (zh) 2004-08-04
CA2439313C (en) 2012-08-07
ATE339521T1 (de) 2006-10-15
WO2002070750A2 (en) 2002-09-12
AU2002238115B2 (en) 2007-06-14
CN1250744C (zh) 2006-04-12
US20030165840A1 (en) 2003-09-04
DE60214725T2 (de) 2007-09-06
HK1068375A1 (en) 2005-04-29
AR032917A1 (es) 2003-12-03
JP2005508603A (ja) 2005-04-07
MXPA03007884A (es) 2004-10-15
EP1409723B1 (en) 2006-09-13

Similar Documents

Publication Publication Date Title
HK1068375A1 (en) Method of determining dihydropyrimidine dehydrogenase gene expression
HK1085244A1 (en) Quantification of gene expression
IL160630A0 (en) Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1
IL160648A0 (en) Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1
HK1076771A1 (en) Method for making an article of unitary construction
AU2002302243A1 (en) Method for determination of co-occurences of attributes
AU2002350332A1 (en) Methods of parallel gene cloning and analysis
AU2003287254A1 (en) Inhibition of gene expression using rna interfering agents
AU2003267036A8 (en) Tubulysin biosynthesis gene
AU2003299864A8 (en) Sirna compounds and methods for the downregulation of gene expression
AU2003260945A1 (en) Methods of use for thermostable rna ligases
GB0416516D0 (en) Method of transducing es cells
GB0123401D0 (en) Methods of inducing gene expression
EP1384782A4 (en) DETECTION PROCEDURE FOR THE EXPRESSION OF AN ASPERGILLUS GENE
AU2261802A (en) Method of analyzing gene expression
AU2002222618A1 (en) Method of analyzing gene expression
IL158004A0 (en) Method of enhancing entomophilous
AU2002359403A8 (en) Methods and compositions for regulation of gene expression through modulation of mrna turnover
IL157694A (en) Method of determining dihydropyrimidine dehydrogenase gene expression
IL162481A0 (en) Method and use of determining genotype
AU2002349681A1 (en) Method of determining cationic surfactant
AU2002342417A1 (en) Inhibitors of dna methyltransferase isoforms
EP1454982A4 (en) PROCESS FOR ANALYZING GENE EXPRESSION
EP1677665A4 (en) ION DETERMINATION USING ION-SENSITIVE ENZYMES
AU2002361399A8 (en) Method for the quantitative determination of gene expression