IL157694A0 - Method of determining dihydropyrimidine dehydrogenase gene expression - Google Patents

Method of determining dihydropyrimidine dehydrogenase gene expression

Info

Publication number
IL157694A0
IL157694A0 IL15769402A IL15769402A IL157694A0 IL 157694 A0 IL157694 A0 IL 157694A0 IL 15769402 A IL15769402 A IL 15769402A IL 15769402 A IL15769402 A IL 15769402A IL 157694 A0 IL157694 A0 IL 157694A0
Authority
IL
Israel
Prior art keywords
gene expression
dehydrogenase gene
dihydropyrimidine dehydrogenase
determining
determining dihydropyrimidine
Prior art date
Application number
IL15769402A
Other languages
English (en)
Original Assignee
Response Genetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/796,807 external-priority patent/US6956111B2/en
Application filed by Response Genetics Inc filed Critical Response Genetics Inc
Publication of IL157694A0 publication Critical patent/IL157694A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
IL15769402A 2001-03-02 2002-02-22 Method of determining dihydropyrimidine dehydrogenase gene expression IL157694A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US09/796,807 US6956111B2 (en) 2001-03-02 2001-03-02 Method of determining dihydropyrimidine dehydrogenase gene expression
US09/842,111 US6905821B2 (en) 2001-03-02 2001-04-26 Method of determining Dihydropyrimidine dehydrogenase gene expression
US09/879,217 US7005278B2 (en) 2001-03-02 2001-06-13 Method of determining dihydropyrimidine dehydrogenase gene expression
PCT/US2002/005221 WO2002070750A2 (en) 2001-03-02 2002-02-22 Method of determining dihydropyrimidine dehydrogenase gene expression

Publications (1)

Publication Number Publication Date
IL157694A0 true IL157694A0 (en) 2004-03-28

Family

ID=27419931

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15769402A IL157694A0 (en) 2001-03-02 2002-02-22 Method of determining dihydropyrimidine dehydrogenase gene expression

Country Status (15)

Country Link
US (1) US7005278B2 (xx)
EP (1) EP1409723B1 (xx)
JP (1) JP2005508603A (xx)
CN (1) CN1250744C (xx)
AR (1) AR032917A1 (xx)
AT (1) ATE339521T1 (xx)
AU (1) AU2002238115B2 (xx)
CA (1) CA2439313C (xx)
DE (1) DE60214725T2 (xx)
HK (1) HK1068375A1 (xx)
IL (1) IL157694A0 (xx)
MX (1) MXPA03007884A (xx)
NZ (1) NZ528374A (xx)
TW (1) TWI274076B (xx)
WO (1) WO2002070750A2 (xx)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020142328A1 (en) 2000-12-01 2002-10-03 Danenberg Kathleen D. Method of determining a chemotherapeutic regimen by assaying gene expression in primary tumors
EP1510588B1 (en) * 2003-08-28 2007-01-31 Roche Diagnostics GmbH Correlation of the ratio of thymidine phosphorylase and dihydropyrimidine dehydrogenase mRNA expression levels in colorectal cancer with disease-free survival in 5-FU treated patients
ZA200706017B (en) * 2005-01-21 2008-12-31 Genentech Inc Fixed dosing of her antibodies
EP1850874B1 (en) * 2005-02-23 2013-10-16 Genentech, Inc. Extending time to disease progression or survival in ovarian cancer patients using pertuzumab
JP2006316040A (ja) 2005-05-13 2006-11-24 Genentech Inc Ｈｅｒｃｅｐｔｉｎ（登録商標）補助療法
US8440398B2 (en) * 2006-01-25 2013-05-14 Taiho Pharmaceutical Co., Ltd. Method for prediction of sensitivity to 5-fluorouracil-type anticancer agent
MX2009008981A (es) 2007-03-02 2009-09-02 Genentech Inc Prediccion de respuesta a un inhibidor her.
ES2417148T3 (es) 2007-06-08 2013-08-06 Genentech, Inc. Marcadores de expresión génica de la resistencia tumoral al tratamiento con inhibidor de HER2
US9551033B2 (en) 2007-06-08 2017-01-24 Genentech, Inc. Gene expression markers of tumor resistance to HER2 inhibitor treatment
WO2009002937A2 (en) 2007-06-22 2008-12-31 Response Genetics, Inc Methods for isolating long fragment rna from fixed samples
BRPI0812682A2 (pt) 2008-06-16 2010-06-22 Genentech Inc tratamento de cáncer de mama metastático
TWI461211B (zh) 2009-03-20 2014-11-21 Genentech Inc 抗－ｈｅｒ抗體
EP2435071A1 (en) 2009-05-29 2012-04-04 F. Hoffmann-La Roche AG Modulators for her2 signaling in her2 expressing patients with gastric cancer
US8079170B2 (en) * 2009-08-28 2011-12-20 Loftin Thomas E Gun barrel cleaning apparatus and method
EP2536748B1 (en) 2010-02-18 2014-08-20 Genentech, Inc. Neuregulin antagonists and use thereof in treating cancer
WO2011146568A1 (en) 2010-05-19 2011-11-24 Genentech, Inc. Predicting response to a her inhibitor
EP2643353A1 (en) 2010-11-24 2013-10-02 Novartis AG Multispecific molecules
WO2012085111A1 (en) 2010-12-23 2012-06-28 F. Hoffmann-La Roche Ag Polypeptide-polynucleotide-complex and its use in targeted effector moiety delivery
JP2014526891A (ja) 2011-08-17 2014-10-09 ジェネンテック， インコーポレイテッド ニューレグリン抗体とその使用
US9327023B2 (en) 2011-10-25 2016-05-03 The Regents Of The University Of Michigan HER2 targeting agent treatment in non-HER2-amplified cancers having HER2 expressing cancer stem cells
RU2019103083A (ru) 2011-11-30 2019-03-22 Дженентек, Инк. МУТАЦИИ ErbB3 ПРИ РАКЕ
WO2013083810A1 (en) 2011-12-09 2013-06-13 F. Hoffmann-La Roche Ag Identification of non-responders to her2 inhibitors
US20130259867A1 (en) 2012-03-27 2013-10-03 Genentech, Inc. Diagnosis and treatments relating to her3 inhibitors
CA2889298C (en) 2012-11-30 2024-01-02 Anton Belousov Identification of patients in need of pd-l1 inhibitor cotherapy
WO2017194554A1 (en) 2016-05-10 2017-11-16 Inserm (Institut National De La Sante Et De La Recherche Medicale) Combinations therapies for the treatment of cancer

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4830969A (en) * 1981-08-31 1989-05-16 The Research Foundation Of State University Of New York Process for the rapid and simple isolation of nucleic acids
US4843155A (en) * 1987-11-19 1989-06-27 Piotr Chomczynski Product and process for isolating RNA
US5128247A (en) * 1989-08-14 1992-07-07 Board Of Regents, The University Of Texas System Methods for isolation of nucleic acids from eukaryotic and prokaryotic sources
US5654179A (en) * 1990-11-14 1997-08-05 Hri Research, Inc. Nucleic acid preparation methods
US5284940A (en) * 1990-11-14 1994-02-08 Hri Research, Inc. Preparation for nucleic acid samples
US5620852A (en) * 1990-11-14 1997-04-15 Hri Research, Inc. Nucleic acid preparation methods
US5346994A (en) * 1992-01-28 1994-09-13 Piotr Chomczynski Shelf-stable product and process for isolating RNA, DNA and proteins
US5502166A (en) * 1992-02-26 1996-03-26 Mitsubishi Chemical Corporation NMDH receptor proteins and genes encoding the same
JP3615545B2 (ja) * 1993-02-01 2005-02-02 キアゲン・エヌ・ブイ 第四級アンモニウム塩界面活性剤及びそのｒｎａの単離剤
US5637687A (en) * 1993-08-31 1997-06-10 Wiggins; James C. Methods and compositions for isolating nucleic acids
AU2289495A (en) 1994-04-13 1995-11-10 Uab Research Foundation, The Dihydropyrimidine dehydrogenase compositions and methods of use
US5643767A (en) * 1994-05-02 1997-07-01 The Rockefeller University Process for isolating cellular components
CA2153215A1 (en) * 1994-07-06 1996-01-07 Lu Wang Treatment of paraffin embedded tissue for gene analysis
US5856454A (en) 1994-09-12 1999-01-05 The United States Of America As Represented By The Department Of Health And Human Services CDNA for human and pig dihydropyrimidine dehydrogenase
US5707802A (en) * 1995-01-13 1998-01-13 Ciba Corning Diagnostics Corp. Nucleic acid probes for the detection and identification of fungi
US5777099A (en) * 1995-02-24 1998-07-07 Biotecx Laboratories, Inc. RNA separation
US5945515A (en) 1995-07-31 1999-08-31 Chomczynski; Piotr Product and process for isolating DNA, RNA and proteins
DE29601618U1 (de) * 1996-01-31 1996-07-04 InViTek GmbH, 13125 Berlin Vorrichtung zur gleichzeitigen multiplen Isolierung
EP0791654A1 (en) * 1996-02-21 1997-08-27 Jürgen A. Dr. Richt Polypeptides corresponding to the amino acid sequences of proteins p57 or p9.5 of Borna disease virus, nucleic acid fragments coding therefore and their use for diagnostic and immunization purposes
DK0896629T3 (da) 1996-03-20 2003-02-03 Us Gov Health & Human Serv Fremgangsmåder og præparater til påvisning af splejsningsdefekter i dihydropyrimidindehydro-genasegenet
EP0912726A4 (en) * 1996-05-10 2001-07-18 Phylomed Corp METHODS FOR OXIDIZING BISULFIDE LINKS WITH OZONE
AU6764398A (en) 1997-03-20 1998-10-12 Variagenics, Inc. Target genes for allele-specific drugs
IT1302026B1 (it) 1997-08-22 2000-07-20 Hoffmann La Roche Materiali immunologici e metodi per la rivelazione di diidropirimidinadeidrogenasi.
US5952202A (en) * 1998-03-26 1999-09-14 The Perkin Elmer Corporation Methods using exogenous, internal controls and analogue blocks during nucleic acid amplification
EP1379686B1 (en) * 2000-12-01 2012-09-05 Response Genetics, Inc. Method of determining epidermal growth factor receptor and her2-neu gene expression and correlation of levels thereof with survival rates
TWI319010B (en) 2000-12-01 2010-01-01 Response Genetics Inc Method of determining a chemotherapeutic regimen by assaying gene expression in primary tumors

Also Published As

Publication number Publication date
WO2002070750A2 (en) 2002-09-12
CN1250744C (zh) 2006-04-12
EP1409723A2 (en) 2004-04-21
JP2005508603A (ja) 2005-04-07
CA2439313C (en) 2012-08-07
US7005278B2 (en) 2006-02-28
DE60214725D1 (de) 2006-10-26
HK1068375A1 (en) 2005-04-29
DE60214725T2 (de) 2007-09-06
TWI274076B (en) 2007-02-21
CA2439313A1 (en) 2002-09-12
EP1409723B1 (en) 2006-09-13
AU2002238115B2 (en) 2007-06-14
ATE339521T1 (de) 2006-10-15
CN1518603A (zh) 2004-08-04
NZ528374A (en) 2008-01-31
AR032917A1 (es) 2003-12-03
WO2002070750A3 (en) 2004-02-19
US20030165840A1 (en) 2003-09-04
MXPA03007884A (es) 2004-10-15

Similar Documents

Publication Publication Date Title
HK1068375A1 (en) Method of determining dihydropyrimidine dehydrogenase gene expression
HK1085244A1 (en) Quantification of gene expression
IL160630A0 (en) Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1
IL160648A0 (en) Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1
HK1076771A1 (en) Method for making an article of unitary construction
AU2002302243A1 (en) Method for determination of co-occurences of attributes
GB0416088D0 (en) Methods of parallel gene cloning and analysis
AU2003287254A1 (en) Inhibition of gene expression using rna interfering agents
AU2003267036A8 (en) Tubulysin biosynthesis gene
AU2003299864A8 (en) Sirna compounds and methods for the downregulation of gene expression
AU2003260945A8 (en) Methods of use for thermostable rna ligases
GB0416516D0 (en) Method of transducing es cells
GB0123401D0 (en) Methods of inducing gene expression
EP1384782A4 (en) DETECTION PROCEDURE FOR THE EXPRESSION OF AN ASPERGILLUS GENE
AU2261802A (en) Method of analyzing gene expression
AU2002222618A1 (en) Method of analyzing gene expression
IL158004A0 (en) Method of enhancing entomophilous
AU2002359403A8 (en) Methods and compositions for regulation of gene expression through modulation of mrna turnover
HK1097571A1 (en) Method of determining dihydropyrimidine dehydrogenase gene expression
IL162481A0 (en) Method and use of determining genotype
AU2002349681A1 (en) Method of determining cationic surfactant
AU2002342417A1 (en) Inhibitors of dna methyltransferase isoforms
EP1454982A4 (en) PROCESS FOR ANALYZING GENE EXPRESSION
EP1677665A4 (en) ION DETERMINATION USING ION-SENSITIVE ENZYMES
AU2002361399A8 (en) Method for the quantitative determination of gene expression