IL155644A0 - Novel crystal and solvate forms of ondansetron hydrochloride and processes for their preparation - Google Patents

Novel crystal and solvate forms of ondansetron hydrochloride and processes for their preparation

Info

Publication number
IL155644A0
IL155644A0 IL15564401A IL15564401A IL155644A0 IL 155644 A0 IL155644 A0 IL 155644A0 IL 15564401 A IL15564401 A IL 15564401A IL 15564401 A IL15564401 A IL 15564401A IL 155644 A0 IL155644 A0 IL 155644A0
Authority
IL
Israel
Prior art keywords
processes
preparation
novel crystal
ondansetron hydrochloride
solvate forms
Prior art date
Application number
IL15564401A
Other languages
English (en)
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma filed Critical Teva Pharma
Publication of IL155644A0 publication Critical patent/IL155644A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Steroid Compounds (AREA)
IL15564401A 2000-10-30 2001-10-30 Novel crystal and solvate forms of ondansetron hydrochloride and processes for their preparation IL155644A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US24428300P 2000-10-30 2000-10-30
US25381900P 2000-11-29 2000-11-29
US26553901P 2001-01-31 2001-01-31
PCT/US2001/048720 WO2002036558A2 (fr) 2000-10-30 2001-10-30 Nouvelles formes de cristaux et solvates de chlorhydrate d'ondansetron et leurs procedes de preparation

Publications (1)

Publication Number Publication Date
IL155644A0 true IL155644A0 (en) 2003-11-23

Family

ID=27399743

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15564401A IL155644A0 (en) 2000-10-30 2001-10-30 Novel crystal and solvate forms of ondansetron hydrochloride and processes for their preparation

Country Status (20)

Country Link
US (1) US20020107275A1 (fr)
EP (1) EP1339707A2 (fr)
JP (1) JP2004525083A (fr)
KR (1) KR20030042038A (fr)
CN (1) CN1498216A (fr)
AU (1) AU2002230935A1 (fr)
CA (1) CA2426026A1 (fr)
CZ (1) CZ20031397A3 (fr)
DE (1) DE01991193T1 (fr)
ES (1) ES2204358T1 (fr)
HR (1) HRP20030432A2 (fr)
HU (1) HUP0401239A2 (fr)
IL (1) IL155644A0 (fr)
IS (1) IS6797A (fr)
MX (1) MXPA03003761A (fr)
NO (1) NO20031928L (fr)
PL (1) PL366150A1 (fr)
SK (1) SK6182003A3 (fr)
WO (1) WO2002036558A2 (fr)
YU (1) YU32003A (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101045704A (zh) * 2001-01-11 2007-10-03 特瓦制药工业有限公司 制备纯二水合昂丹司琼盐酸盐的改进方法
US7098345B2 (en) 2002-04-29 2006-08-29 TEVA Gyógyszergyár Zárkörüen Müködö Részvénytársaság Process for preparing 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-YL)methyl]-4H-carbazol-4-one
FI6164U1 (fi) * 2003-01-09 2004-03-15 Synthon Bv Ondansetronmuotoja
US7547791B2 (en) * 2004-10-26 2009-06-16 Ipca Laboratories Ltd. One-pot process for the preparation of antiemetic agent, 1,2,3,9-tetrahydro-9-methyl-3[(2-methyl)-1H-imidazole-1-yl)methyl]-4H-carbazol-4-O
WO2007090091A2 (fr) * 2006-01-27 2007-08-09 Eurand, Inc. Système d'administration de médicaments comprenant des médicaments faiblement basiques et des acides organiques
CN101410094B (zh) * 2006-01-27 2013-04-17 阿普塔利斯制药股份有限公司 包含弱碱性选择性5-羟色胺5-ht3阻断剂和有机酸的药物递送系统
JP2010512333A (ja) * 2006-12-07 2010-04-22 ヘルシン ヘルスケア ソシエテ アノニム 塩酸パロノセトロンの結晶及び非晶質形
US8133506B2 (en) 2008-03-12 2012-03-13 Aptalis Pharmatech, Inc. Drug delivery systems comprising weakly basic drugs and organic acids
CN102190595A (zh) * 2010-03-17 2011-09-21 上海医药工业研究院 阿戈美拉汀溴化氢水合物及其制备方法
CN102190594A (zh) * 2010-03-17 2011-09-21 上海医药工业研究院 阿戈美拉汀氯化氢水合物及其制备方法
CR20160222U (es) 2013-11-15 2016-08-26 Akebia Therapeutics Inc Formas solidas de acido { [ -(3- clorofenil) -3- hidroxipiridin -2-carbonil] amino} acetico, composiciones, y usos de las mismas

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4695578A (en) * 1984-01-25 1987-09-22 Glaxo Group Limited 1,2,3,9-tetrahydro-3-imidazol-1-ylmethyl-4H-carbazol-4-ones, composition containing them, and method of using them to treat neuronal 5HT function disturbances
EP0201165B1 (fr) * 1985-03-14 1994-07-20 Beecham Group Plc Médicaments pour le traitement de l'éméticité
GB8518742D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Process
GB8518741D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Process
GB8630071D0 (en) * 1986-12-17 1987-01-28 Glaxo Group Ltd Medicaments
GB8816187D0 (en) * 1988-07-07 1988-08-10 Glaxo Group Ltd Medicaments
US5344658A (en) * 1989-06-28 1994-09-06 Glaxo Group Limited Process and composition using ondansetron
CA2112487C (fr) * 1991-06-26 2003-04-15 James W. Young Methode et compositions pour le traitement des vomissements, des nausees et d'autres troubles a l'ondansetron optiquement pur r(+)
CA2106642C (fr) * 1992-10-14 2005-08-16 Peter Bod Derives de carbazolone et procede d'obtention
GB9423511D0 (en) * 1994-11-22 1995-01-11 Glaxo Wellcome Inc Compositions
GB9423588D0 (en) * 1994-11-22 1995-01-11 Glaxo Wellcome Inc Compositions
CN1045437C (zh) * 1994-12-29 1999-10-06 中国科学院上海有机化学研究所 恩丹西酮及其生理盐的合成
EP1207160A1 (fr) * 2000-11-20 2002-05-22 Hanmi Pharm. Co., Ltd. Procédé de préparation de la 1,2,3,9-tétrahydro-9-méthyl-3-((2-méthyl-1H-imidazol-1-yl)-méthyl)-4H-carbazol-4-one
US7098345B2 (en) * 2002-04-29 2006-08-29 TEVA Gyógyszergyár Zárkörüen Müködö Részvénytársaság Process for preparing 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-YL)methyl]-4H-carbazol-4-one
EP1465887A1 (fr) * 2002-04-30 2004-10-13 Teva Gyogyszergyar Reszvenytarsasag Nouvelles formes cristallines d'ondansetron, procedes de preparation correspondant, compositions pharmaceutiques contenant ces nouvelles formes et procedes de traitement de la nausee au moyen des ces nouvelles formes

Also Published As

Publication number Publication date
EP1339707A2 (fr) 2003-09-03
CZ20031397A3 (cs) 2003-11-12
DE01991193T1 (de) 2004-07-08
NO20031928L (no) 2003-06-27
WO2002036558A3 (fr) 2003-02-06
HUP0401239A2 (hu) 2004-12-28
CN1498216A (zh) 2004-05-19
US20020107275A1 (en) 2002-08-08
MXPA03003761A (es) 2003-07-28
IS6797A (is) 2003-04-29
HRP20030432A2 (en) 2004-06-30
WO2002036558A2 (fr) 2002-05-10
PL366150A1 (en) 2005-01-24
SK6182003A3 (en) 2004-03-02
YU32003A (sh) 2006-05-25
AU2002230935A1 (en) 2002-05-15
JP2004525083A (ja) 2004-08-19
NO20031928D0 (no) 2003-04-29
ES2204358T1 (es) 2004-05-01
CA2426026A1 (fr) 2002-05-10
KR20030042038A (ko) 2003-05-27

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