IL155249A0 - Methods of isolating bipotent hepatic progenitor cells - Google Patents

Methods of isolating bipotent hepatic progenitor cells

Info

Publication number
IL155249A0
IL155249A0 IL15524900A IL15524900A IL155249A0 IL 155249 A0 IL155249 A0 IL 155249A0 IL 15524900 A IL15524900 A IL 15524900A IL 15524900 A IL15524900 A IL 15524900A IL 155249 A0 IL155249 A0 IL 155249A0
Authority
IL
Israel
Prior art keywords
progenitors
cells
hepatic
antigen
cell
Prior art date
Application number
IL15524900A
Other languages
English (en)
Original Assignee
Univ North Carolina
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ North Carolina filed Critical Univ North Carolina
Publication of IL155249A0 publication Critical patent/IL155249A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/067—Hepatocytes
    • C12N5/0672—Stem cells; Progenitor cells; Precursor cells; Oval cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Obesity (AREA)
  • Cell Biology (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
IL15524900A 2000-10-03 2000-10-03 Methods of isolating bipotent hepatic progenitor cells IL155249A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2000/027429 WO2002028997A2 (en) 2000-10-03 2000-10-03 Methods of isolating bipotent hepatic progenitor cells

Publications (1)

Publication Number Publication Date
IL155249A0 true IL155249A0 (en) 2003-11-23

Family

ID=21741847

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15524900A IL155249A0 (en) 2000-10-03 2000-10-03 Methods of isolating bipotent hepatic progenitor cells
IL155249A IL155249A (en) 2000-10-03 2003-04-03 Population of cells enriched in isolated bipotent hepatic progenitors and methods for obtaining the same

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL155249A IL155249A (en) 2000-10-03 2003-04-03 Population of cells enriched in isolated bipotent hepatic progenitors and methods for obtaining the same

Country Status (11)

Country Link
EP (1) EP1325112B1 (ja)
JP (1) JP2004510432A (ja)
CN (1) CN1258589C (ja)
AT (1) ATE510905T1 (ja)
AU (2) AU2000278582B2 (ja)
CA (1) CA2424781C (ja)
DK (1) DK1325112T3 (ja)
ES (1) ES2367005T3 (ja)
HK (1) HK1054569B (ja)
IL (2) IL155249A0 (ja)
WO (1) WO2002028997A2 (ja)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020187133A1 (en) 1999-10-01 2002-12-12 Hiroshi Kubota Methods of isolating bipotent hepatic progenitor cells
AU7753500A (en) * 2000-10-03 2002-04-15 Univ North Carolina Processes for clonal growth of hepatic progenitor cells
ES2328466T3 (es) 2001-03-27 2009-11-13 Vertex Pharmaceuticals Incorporated Composiciones y metodos utiles para la infeccion por hcv.
DE60221987T2 (de) 2001-06-22 2008-05-15 Stemcells, Inc., Palo Alto Le-zellen (liver engrafting cells), assays und verwendungen davon
US20060040386A1 (en) * 2004-01-14 2006-02-23 Suchitra Holgersson Human hepatic progenitor cells and methods of use thereof
WO2009013254A1 (en) 2007-07-20 2009-01-29 Cellartis Ab A novel population of hepatocytes derived via definitive endoderm (de-hep) from human blastocysts stem cells
PE20141521A1 (es) * 2011-08-23 2014-10-25 Roche Glycart Ag Moleculas biespecificas de union a antigeno activadoras de celulas t
ES2954834T3 (es) 2014-08-28 2023-11-27 Cellaion Sa Método para producir células progenitoras del hígado adulto
JP6836990B2 (ja) 2014-11-26 2021-03-03 アクセラレイテッド・バイオサイエンシズ・コーポレーション 誘導肝細胞およびそれらの使用
JP6704617B2 (ja) * 2016-01-29 2020-06-03 北海道公立大学法人 札幌医科大学 小型肝細胞の継代培養方法
CN109385394A (zh) * 2018-11-02 2019-02-26 大连理工大学 一种提取、分离和培养同体异种肝原代细胞的方法
SG11202106169SA (en) * 2018-12-14 2021-07-29 Promethera Therapeutics Sa Cell composition comprising liver progenitor cells expressing hla-e

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6129911A (en) * 1998-07-10 2000-10-10 Rhode Island Hospital, A Lifespan Partner Liver stem cell
CA2877233A1 (en) * 1999-01-19 2000-07-27 Lola M. Reid Human liver progenitors

Also Published As

Publication number Publication date
AU2000278582B2 (en) 2007-08-30
CA2424781C (en) 2018-11-06
WO2002028997A3 (en) 2002-09-12
CA2424781A1 (en) 2002-04-11
ES2367005T3 (es) 2011-10-27
AU7858200A (en) 2002-04-15
EP1325112A2 (en) 2003-07-09
IL155249A (en) 2011-12-29
JP2004510432A (ja) 2004-04-08
WO2002028997A2 (en) 2002-04-11
CN1258589C (zh) 2006-06-07
HK1054569B (zh) 2012-03-02
ATE510905T1 (de) 2011-06-15
EP1325112B1 (en) 2011-05-25
HK1054569A1 (en) 2003-12-05
CN1461340A (zh) 2003-12-10
DK1325112T3 (da) 2011-09-12

Similar Documents

Publication Publication Date Title
Wong et al. Multilineage potential and self-renewal define an epithelial progenitor cell population in the adult thymus
HK1054569A1 (en) Methods of isolating bipotent hepatic progenitor cells
Vroman et al. Development and characterization of polarized primary cultures of rat intrahepatic bile duct epithelial cells.
Austin et al. Hepatic regeneration from hematopoietic stem cells
CN103989710B (zh) 分离的肝脏干细胞
Pfeiffer et al. Differentiation of a teratocarcinoma line: preferential development of cholinergic neurons.
Bonilla et al. Functional neural stem cells derived from adult bone marrow
de Pooter et al. In vitro generation of T lymphocytes from embryonic stem cell–derived prehematopoietic progenitors
WO2003104411A3 (en) BIOARTIFICIAL LIVER SYSTEM
ATE449837T1 (de) Abstammungs-spezifische zellen und vorläuferzellen
WO2001081549A3 (en) Hepatocyte lineage cells derived from pluripotent stem cells
HK1176641A1 (en) Human liver progenitors
JP2012507304A5 (ja)
CN101553564B (zh) 肝星状细胞前体及其分离方法
Laurson et al. Hepatocyte progenitors in man and in rodents–multiple pathways, multiple candidates
BRPI0710339A2 (pt) método de modulação de uma reação imunólogica, método de redução e extrato
Cunningham et al. Regulation and function of adhesion molecule expression by human alveolar epithelial cells.
Peng et al. Comparison of biological characteristics of marrow mesenchymal stem cells in hepatitis B patients and normal adults
Almeida-Porada et al. A large animal noninjury model for study of human stem cell plasticity
Borena et al. Sphere-forming capacity as an enrichment strategy for epithelial-like stem cells from equine skin
Pouliot et al. Optimization of a transplant model to assess skin reconstitution from stem cell‐enriched primary human keratinocyte populations
Poliakova et al. Presence of nonhematopoietic side population cells in the adult human and nonhuman primate pancreas
LeBleu et al. Genetic reprogramming with stem cells regenerates glomerular epithelial podocytes in Alport syndrome
Goss Arginine synthesis by hepatomas in vitro: II. Isolation and characterization of morris hepatoma variants unable to convert ornithine to arginine, and modulation of urea-cycle enzymes by dexamethasone and cyclic-amp
Fang A Further Discussion on Suburbanization of Beijing Municipality