IL155213A0 - Ketone compounds and compositions for cholesterol management and related uses - Google Patents
Ketone compounds and compositions for cholesterol management and related usesInfo
- Publication number
- IL155213A0 IL155213A0 IL15521301A IL15521301A IL155213A0 IL 155213 A0 IL155213 A0 IL 155213A0 IL 15521301 A IL15521301 A IL 15521301A IL 15521301 A IL15521301 A IL 15521301A IL 155213 A0 IL155213 A0 IL 155213A0
- Authority
- IL
- Israel
- Prior art keywords
- compositions
- ketone compounds
- related uses
- cholesterol management
- cholesterol
- Prior art date
Links
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title 2
- -1 Ketone compounds Chemical class 0.000 title 1
- 235000012000 cholesterol Nutrition 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
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- C07F9/24—Esteramides
- C07F9/2404—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
- C07F9/2425—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic containing the structure (RX)(RR'N)P(=Y)-Z-(C)n-Z'-P(=Y)(XR)2 (X = O, S, NR; Y = O, S, electron pair; Z = O, S; Z' = O, S)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/44—Amides thereof
- C07F9/4403—Amides thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4423—Amides of poly (thio)phosphonic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Crystallography & Structural Chemistry (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Communicable Diseases (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Child & Adolescent Psychology (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23923200P | 2000-10-11 | 2000-10-11 | |
PCT/US2001/031872 WO2002030860A2 (fr) | 2000-10-11 | 2001-10-11 | Composes de fonction cetone et compositions pour la regulation du taux de cholesterol, et utilisations associees |
Publications (1)
Publication Number | Publication Date |
---|---|
IL155213A0 true IL155213A0 (en) | 2003-11-23 |
Family
ID=22901210
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15521301A IL155213A0 (en) | 2000-10-11 | 2001-10-11 | Ketone compounds and compositions for cholesterol management and related uses |
IL155213A IL155213A (en) | 2000-10-11 | 2003-04-03 | Ketones and their use in the preparation of pharmaceuticals |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL155213A IL155213A (en) | 2000-10-11 | 2003-04-03 | Ketones and their use in the preparation of pharmaceuticals |
Country Status (11)
Country | Link |
---|---|
US (1) | US6699910B2 (fr) |
EP (1) | EP1326822A2 (fr) |
JP (1) | JP2004511453A (fr) |
CN (2) | CN1283610C (fr) |
AU (2) | AU2002213136B2 (fr) |
BR (1) | BRPI0114622B8 (fr) |
CA (1) | CA2425311C (fr) |
HK (1) | HK1063461A1 (fr) |
IL (2) | IL155213A0 (fr) |
MX (1) | MXPA03003020A (fr) |
WO (1) | WO2002030860A2 (fr) |
Families Citing this family (36)
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US8568766B2 (en) | 2000-08-24 | 2013-10-29 | Gattadahalli M. Anantharamaiah | Peptides and peptide mimetics to treat pathologies associated with eye disease |
US20040122091A1 (en) * | 2000-10-11 | 2004-06-24 | Esperion Therapeutics, Inc. | Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol management and related uses |
US7304093B2 (en) * | 2000-10-11 | 2007-12-04 | Esperion Therapeutics, Inc. | Ketone compounds and compositions for cholesterol management and related uses |
US20050003041A1 (en) * | 2001-05-01 | 2005-01-06 | Gerhard Kamil | Application of fluid bed technology in brewing |
US20030236212A1 (en) * | 2002-04-10 | 2003-12-25 | Jean-Louis Dasseux | Functionalized long chain derivatives as acyl coenzyme-A mimics, compositions thereof, and methods of cholesterol management and related uses |
US20040148013A1 (en) * | 2002-04-18 | 2004-07-29 | Epstein Stephen E | Stent-based delivery statins to prevent restenosis |
US20040048910A1 (en) * | 2002-08-22 | 2004-03-11 | Bove Susan Elizabeth | Method of treating osteoarthritis |
MXPA05007674A (es) * | 2003-01-23 | 2005-09-22 | Esperion Therapeutics Inc | Compuestos de hidroxilo y composiciones para el manejo del colesterol y usos relacionados. |
BR0318685A (pt) | 2003-12-24 | 2006-12-19 | Esperion Therapeutics Inc | compostos de cetona e composições para controle de colesterol e usos relacionados |
EP1890715A4 (fr) | 2005-04-29 | 2009-10-28 | Univ California | Peptides et mimetiques de peptides destines a traiter les pathologies caracterisees par une reaction inflammatoire |
CA2659655A1 (fr) | 2006-08-08 | 2008-02-21 | Alan M. Fogelman | Les salicylanilides renforcent l'administration par voie orale de peptides therapeutiques |
IL181577A0 (en) * | 2007-02-26 | 2007-07-04 | Jacob Bar Tana | Combination therapy composition and methods for the treatment of cardiovascular disorders and immune-related disorders |
WO2009032693A2 (fr) | 2007-08-28 | 2009-03-12 | Uab Research Foundation | Polypeptides de synthèse imitant l'apolipoprotéine e et leurs procédés d'utilisation |
US8557767B2 (en) | 2007-08-28 | 2013-10-15 | Uab Research Foundation | Synthetic apolipoprotein E mimicking polypeptides and methods of use |
US8815508B2 (en) * | 2008-08-12 | 2014-08-26 | Zinfandel Pharmaceuticals, Inc. | Method of identifying disease risk factors |
US8846315B2 (en) | 2008-08-12 | 2014-09-30 | Zinfandel Pharmaceuticals, Inc. | Disease risk factors and methods of use |
EP2334188A4 (fr) * | 2008-08-15 | 2012-08-08 | Burnham Inst Medical Research | Composition et procédés utilisables en vue de la conception et du développement d'inhibiteurs des métalloenzymes |
WO2011143362A1 (fr) | 2010-05-11 | 2011-11-17 | Esperion Therapeutics, Inc. | Variants d'apolipoprotéine a1 résistants à l'oxydation dimères |
RU2013118021A (ru) | 2010-09-20 | 2014-10-27 | Кареус Терапьютикс, Са | Способы и композиции для лечения сахарного диабета и дислипидемии |
UA114704C2 (uk) | 2011-01-10 | 2017-07-25 | Зінфандел Фармасьютікалз, Інк. | Способи та лікарські засоби для лікування хвороби альцгеймера |
DE102011078416A1 (de) * | 2011-06-30 | 2013-01-03 | Henkel Ag & Co. Kgaa | Photolabile Duftspeicherstoffe |
EP3137899A2 (fr) | 2014-05-02 | 2017-03-08 | Cerenis Therapeutics Holding SA | Marqueurs de thérapie hdl |
EP3189069B1 (fr) | 2014-07-31 | 2024-10-23 | UAB Research Foundation | Peptides e-mimétiques d'apo ayant une puissance supérieure afin de dégager le taux de cholestérol plasmatique |
CN107530307A (zh) | 2015-03-13 | 2018-01-02 | 艾斯柏伦治疗公司 | 包含etc1002和依泽替米贝的固定剂量组合和制剂以及治疗心血管疾病或降低心血管疾病风险的方法 |
MA41793A (fr) | 2015-03-16 | 2018-01-23 | Esperion Therapeutics Inc | Associations de doses fixes comprenant du etc1002 et une ou plusieurs statines permettant de traiter ou de réduire un risque cardiovasculaire |
KR101772440B1 (ko) | 2015-08-31 | 2017-08-30 | 한국식품연구원 | 4-(4-하이드록시-4-메틸펜틸)-3-사이클로-헥센-1-카복스알데하이드를 포함하는 신생혈관형성 촉진용 조성물 |
GB201522302D0 (en) * | 2015-12-17 | 2016-02-03 | Mars Inc | Food product for regulating lipid metabolites |
CN107118098B (zh) * | 2016-02-25 | 2020-07-14 | 中国科学院上海药物研究所 | 一类脂肪酸类化合物、其制备方法及其用途 |
WO2020141419A2 (fr) * | 2018-12-31 | 2020-07-09 | Lupin Limited | Nouveaux sels et formes polymorphes d'acide bempedoïque |
EP3986860A1 (fr) | 2019-06-21 | 2022-04-27 | Esperion Therapeutics, Inc. | Formes salines d'acide bempedoïque et leurs procédés d'utilisation |
CN114126593B (zh) | 2019-07-26 | 2024-07-26 | 埃斯佩尔维塔治疗股份有限公司 | 可用于预防或治疗疾病的官能化的长链烃一元和二元羧酸 |
WO2021252607A1 (fr) * | 2020-06-12 | 2021-12-16 | Novomer, Inc. | Composés de bêta-propiolactone et composés de bêta-propiolactone à cycle ouvert et leurs utilisations |
TW202245804A (zh) | 2021-01-25 | 2022-12-01 | 美商艾斯佩維他治療學公司 | 官能化長鏈烴單羧酸及二羧酸及其衍生物以及其於預防或治療疾病之用途 |
WO2022159808A2 (fr) * | 2021-01-25 | 2022-07-28 | Espervita Therapeutics, Inc. | Acides monocarboxyliques et dicarboxyliques à chaîne longue fonctionnalisés et leurs dérivés, et leur utilisation pour la prévention ou le traitement d'une maladie |
AU2022381258A1 (en) * | 2021-11-03 | 2024-05-02 | Tuojie Biotech (Shanghai) Co., Ltd. | Substituted phenylpropionic acid derivative and use thereof |
WO2024199070A1 (fr) * | 2023-03-24 | 2024-10-03 | 上海京新生物医药有限公司 | Dérivé d'amine cyclique, composition et utilisation associées |
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US3441605A (en) | 1965-02-17 | 1969-04-29 | Wallace & Tiernan Inc | Diketo-dicarboxylic acids and salts and preparation thereof by alkaline oxidation |
US3773946A (en) | 1969-09-02 | 1973-11-20 | Parke Davis & Co | Triglyceride-lowering compositions and methods |
US3930024A (en) | 1969-09-02 | 1975-12-30 | Parke Davis & Co | Pharmaceutical compositions and methods |
JPS5522636A (en) | 1978-08-04 | 1980-02-18 | Takeda Chem Ind Ltd | Thiazoliding derivative |
JPS5639033A (en) | 1979-09-04 | 1981-04-14 | Kao Corp | Alpha-mono(methyl-branched alkyl glyceryl ether and skin cosmetic containing the same |
IL64542A0 (en) | 1981-12-15 | 1982-03-31 | Yissum Res Dev Co | Long-chain alpha,omega-dicarboxylic acids and derivatives thereof and pharmaceutical compositions containing them |
IT1164254B (it) | 1983-05-30 | 1987-04-08 | Luso Farmaco Inst | 3-(3-idrossibutossi)-1-butanolo e suo metodo di preparazione |
JPS60136512A (ja) | 1983-12-26 | 1985-07-20 | Eisai Co Ltd | 脂質代謝改善剤 |
DE3423166A1 (de) | 1984-06-22 | 1986-01-02 | Epis S.A., Zug | Alpha-, omega-dicarbonsaeuren, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten |
JP2999579B2 (ja) | 1990-07-18 | 2000-01-17 | 武田薬品工業株式会社 | Dnaおよびその用途 |
US5254589A (en) | 1991-10-15 | 1993-10-19 | Warner-Lambert Company | Sulfonyl urea and carbamate ACAT inhibitors |
IL109431A (en) | 1993-05-14 | 2001-01-11 | Warner Lambert Co | Pharmaceutical compositions containing n-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters), for regulating plasma cholesterol concentration, and certain such novel compounds |
US5420339A (en) | 1993-11-22 | 1995-05-30 | Warner-Lambert Company | Alpha-aryl or heteroaryl-substituted amide ester ACAT inhibitors |
US5504073A (en) | 1994-07-01 | 1996-04-02 | Warner-Lambert Company | PLA2 inhibitors and their use for inhibition of intestinal cholesterol absorption |
US5578639A (en) | 1994-07-01 | 1996-11-26 | Warner-Lambert Company | PLA2 inhibitors and their use for inhibition of intestinal cholesterol absorption |
US5648387A (en) | 1995-03-24 | 1997-07-15 | Warner-Lambert Company | Carboxyalkylethers, formulations, and treatment of vascular diseases |
EA000514B1 (ru) | 1995-11-02 | 1999-10-28 | Варнер-Ламберт Компани | Способ нормализации липопротеидного профиля плазмы крови у млекопитающего и фармацевтическая композиция для его осуществления |
US5807846A (en) | 1996-11-14 | 1998-09-15 | Warner-Lambert Company | Phosphonamide ACAT inhibitors |
IL119971A (en) | 1997-01-07 | 2003-02-12 | Yissum Res Dev Co | Pharmaceutical compositions containing dicarboxylic acids and derivatives thereof and some novel dicarboxylic acids |
US6093744A (en) | 1997-04-21 | 2000-07-25 | Warner-Lambert Company | N-acyl sulfamic acid esters useful as hypocholesterolemic agents |
IL121165A0 (en) | 1997-06-26 | 1997-11-20 | Yissum Res Dev Co | Pharmaceutical compositions containing carboxylic acids and derivatives thereof |
ATE298343T1 (de) | 1999-04-28 | 2005-07-15 | Univ Georgetown | Ligande für metabotropische glutamat-rezeptoren |
WO2001046110A2 (fr) * | 1999-12-23 | 2001-06-28 | The University Of Georgia Research Foundation, Inc. | Chalcone et ses analogues comme agents inhibiteurs de l'angiogenese et des etats pathologiques associes |
-
2001
- 2001-10-11 CA CA2425311A patent/CA2425311C/fr not_active Expired - Lifetime
- 2001-10-11 AU AU2002213136A patent/AU2002213136B2/en not_active Expired
- 2001-10-11 MX MXPA03003020A patent/MXPA03003020A/es active IP Right Grant
- 2001-10-11 JP JP2002534250A patent/JP2004511453A/ja not_active Withdrawn
- 2001-10-11 CN CNB018202470A patent/CN1283610C/zh not_active Expired - Lifetime
- 2001-10-11 CN CNA2006101540229A patent/CN1962596A/zh active Pending
- 2001-10-11 BR BRPI0114622A patent/BRPI0114622B8/pt not_active IP Right Cessation
- 2001-10-11 WO PCT/US2001/031872 patent/WO2002030860A2/fr active Application Filing
- 2001-10-11 IL IL15521301A patent/IL155213A0/xx unknown
- 2001-10-11 AU AU1313602A patent/AU1313602A/xx active Pending
- 2001-10-11 US US09/976,938 patent/US6699910B2/en not_active Expired - Lifetime
- 2001-10-11 EP EP01981499A patent/EP1326822A2/fr not_active Withdrawn
-
2003
- 2003-04-03 IL IL155213A patent/IL155213A/en active IP Right Grant
-
2004
- 2004-08-20 HK HK04106257A patent/HK1063461A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO2002030860A2 (fr) | 2002-04-18 |
WO2002030860A3 (fr) | 2002-08-15 |
IL155213A (en) | 2011-12-29 |
CN1283610C (zh) | 2006-11-08 |
US20030078239A1 (en) | 2003-04-24 |
AU1313602A (en) | 2002-04-22 |
AU2002213136B2 (en) | 2007-01-04 |
BRPI0114622B1 (pt) | 2016-07-05 |
US6699910B2 (en) | 2004-03-02 |
BRPI0114622B8 (pt) | 2021-05-25 |
BR0114622A (pt) | 2004-06-29 |
MXPA03003020A (es) | 2003-07-14 |
CN1962596A (zh) | 2007-05-16 |
CA2425311A1 (fr) | 2002-04-18 |
CA2425311C (fr) | 2011-06-14 |
CN1479712A (zh) | 2004-03-03 |
EP1326822A2 (fr) | 2003-07-16 |
JP2004511453A (ja) | 2004-04-15 |
HK1063461A1 (en) | 2004-12-31 |
WO2002030860A9 (fr) | 2003-02-20 |
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