IL154545A0 - Orally administered peptides to ameliorate atherosclerosis - Google Patents
Orally administered peptides to ameliorate atherosclerosisInfo
- Publication number
- IL154545A0 IL154545A0 IL15454501A IL15454501A IL154545A0 IL 154545 A0 IL154545 A0 IL 154545A0 IL 15454501 A IL15454501 A IL 15454501A IL 15454501 A IL15454501 A IL 15454501A IL 154545 A0 IL154545 A0 IL 154545A0
- Authority
- IL
- Israel
- Prior art keywords
- orally administered
- peptides
- administered peptides
- ameliorate
- atherosclerosis
- Prior art date
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 201000001320 Atherosclerosis Diseases 0.000 title abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
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- A61P39/06—Free radical scavengers or antioxidants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/08—Vasodilators for multiple indications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/12—Antihypertensives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Obesity (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pulmonology (AREA)
- Genetics & Genomics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Vascular Medicine (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/645,454 US6664230B1 (en) | 2000-08-24 | 2000-08-24 | Orally administered peptides to ameliorate atherosclerosis |
| PCT/US2001/026497 WO2002015923A1 (en) | 2000-08-24 | 2001-08-23 | Orally administered peptides to ameliorate atherosclerosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL154545A0 true IL154545A0 (en) | 2003-09-17 |
Family
ID=24589089
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15454501A IL154545A0 (en) | 2000-08-24 | 2001-08-23 | Orally administered peptides to ameliorate atherosclerosis |
| IL154545A IL154545A (en) | 2000-08-24 | 2003-02-19 | Peptide comprising at least one " d" amino acid for amelioration of a symptom of atherosclerosis |
| IL206114A IL206114A (en) | 2000-08-24 | 2010-05-31 | Peptides given orally to treat atherosclerosis |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL154545A IL154545A (en) | 2000-08-24 | 2003-02-19 | Peptide comprising at least one " d" amino acid for amelioration of a symptom of atherosclerosis |
| IL206114A IL206114A (en) | 2000-08-24 | 2010-05-31 | Peptides given orally to treat atherosclerosis |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US6664230B1 (enExample) |
| EP (3) | EP1318828B1 (enExample) |
| JP (6) | JP3822167B2 (enExample) |
| CN (6) | CN1943781B (enExample) |
| AT (2) | ATE506958T1 (enExample) |
| AU (4) | AU2001286732B2 (enExample) |
| CA (3) | CA2639651C (enExample) |
| CY (1) | CY1110204T1 (enExample) |
| DE (2) | DE60141842D1 (enExample) |
| DK (1) | DK1318828T3 (enExample) |
| EA (2) | EA009528B1 (enExample) |
| ES (2) | ES2342258T3 (enExample) |
| IL (3) | IL154545A0 (enExample) |
| PT (1) | PT1318828E (enExample) |
| WO (1) | WO2002015923A1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7531514B2 (en) | 2000-08-24 | 2009-05-12 | The Regents Of The University Of California | Orally administered peptides synergize statin activity |
| US7579319B2 (en) | 2004-12-06 | 2009-08-25 | The Regents Of The University Of California | Methods for improving the structure and function of arterioles |
Families Citing this family (89)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8568766B2 (en) | 2000-08-24 | 2013-10-29 | Gattadahalli M. Anantharamaiah | Peptides and peptide mimetics to treat pathologies associated with eye disease |
| US7148197B2 (en) * | 2000-08-24 | 2006-12-12 | The Regents Of The University Of California | Orally administered small peptides synergize statin activity |
| US7166578B2 (en) * | 2000-08-24 | 2007-01-23 | The Regents Of The University Of California | Orally administered peptides synergize statin activity |
| US6664230B1 (en) * | 2000-08-24 | 2003-12-16 | The Regents Of The University Of California | Orally administered peptides to ameliorate atherosclerosis |
| US7723303B2 (en) | 2000-08-24 | 2010-05-25 | The Regents Of The University Of California | Peptides and peptide mimetics to treat pathologies characterized by an inflammatory response |
| US7144862B2 (en) * | 2000-08-24 | 2006-12-05 | The Regents Of The University Of California | Orally administered peptides to ameliorate atherosclerosis |
| US6930085B2 (en) * | 2002-04-05 | 2005-08-16 | The Regents Of The University Of California | G-type peptides to ameliorate atherosclerosis |
| DE10222234A1 (de) * | 2002-05-16 | 2003-11-27 | Roche Diagnostics Gmbh | Kontroll- und Kalibrationsmaterial für Blutgerinnungstests |
| WO2004041179A2 (en) * | 2002-10-30 | 2004-05-21 | The United States Of America As Represented By The Secretary Of Health And Human Services, Nih | Scavenger receptor b1 (cla-1) targeting for the treatment of infection, sepsis and inflammation |
| EP1599173B1 (en) * | 2002-11-13 | 2017-02-22 | The Uab Research Foundation | Synthetic single domain polypeptides mimicking apolipoprotein e and methods of use |
| US20050159362A1 (en) * | 2003-04-22 | 2005-07-21 | Sircar Jagadish C. | Mediators of reverse cholesterol transport for the treatment of hypercholesterolemia |
| MXJL05000046A (es) * | 2003-04-22 | 2005-12-22 | Avanir Pharmaceuticals | Mediadores de transporte reverso de colesterol para el tratamiento de hipercolesterolemia. |
| GB0311081D0 (en) * | 2003-05-14 | 2003-06-18 | Btg Internat Limted | Treatment of neurodegenerative conditions |
| FI20060154A7 (fi) * | 2003-08-18 | 2006-05-11 | Btg Int Ltd | Neurogeneratiivisten tilojen hoito |
| US7781219B2 (en) | 2003-12-05 | 2010-08-24 | The Cleveland Clinic Foundation | Risk markers for cardiovascular disease |
| GB0329958D0 (en) | 2003-12-24 | 2004-01-28 | Univ Manchester | Treatment of viral infections |
| GB0404374D0 (en) | 2004-02-27 | 2004-03-31 | Univ Manchester | Treatment of bacterial infections |
| CA2776927C (en) * | 2004-04-15 | 2014-08-12 | Athera Biotechnologies Ab | Phosphorylcholine conjugates and corresponding antibodies |
| EP1750862B1 (en) * | 2004-06-04 | 2011-01-05 | Teva Pharmaceutical Industries Ltd. | Pharmaceutical composition containing irbesartan |
| MXJL06000068A (es) * | 2004-06-09 | 2007-04-10 | Avanir Pharmaceuticals | Mediadores del transporte inverso de colesterol para el tratamiento de hipercolesterolemia. |
| EP1753733A1 (en) * | 2004-06-09 | 2007-02-21 | Avanir Pharmaceuticals | Small molecules for treatment of hypercholesterolemia and related diseases |
| WO2005123686A1 (en) * | 2004-06-09 | 2005-12-29 | Avanir Pharmaceuticals | Heterocyclic derivatives for treatment of hyperlipidemia and related diseases |
| BRPI0513402A (pt) * | 2004-07-16 | 2008-05-06 | Tufts College | miméticos de apolipoproteìna a1 e usos dos mesmos |
| WO2006020498A2 (en) * | 2004-08-11 | 2006-02-23 | The Cleveland Clinic Foundation | Therapeutic agents and methods for cardiovascular disease |
| CA2577026A1 (en) * | 2004-08-11 | 2006-02-23 | The Regents Of The University Of California | Orally administered small peptides synergize statin activity |
| US20060205669A1 (en) * | 2004-09-16 | 2006-09-14 | The Regents Of The University Of California | G-type peptides and other agents to ameliorate atherosclerosis and other pathologies |
| WO2006053754A1 (en) * | 2004-11-19 | 2006-05-26 | Novartis Ag | COMBINATIONS OF ANTI-ATHEROSCLEROTIC PEPTIDES AND AN mTOR INHIBITING AGENT AND THEIR METHODS OF USE |
| GB0425932D0 (en) * | 2004-11-25 | 2004-12-29 | Btg Int Ltd | Structured phospholipids |
| GB0504333D0 (en) * | 2005-03-02 | 2005-04-06 | Btg Int Ltd | Treatment of cytokine dysregulation |
| GB0504362D0 (en) * | 2005-03-02 | 2005-04-06 | Btg Int Ltd | Cytokine modulators |
| US8206750B2 (en) | 2005-03-24 | 2012-06-26 | Cerenis Therapeutics Holding S.A. | Charged lipoprotein complexes and their uses |
| EA200900786A1 (ru) | 2005-04-29 | 2009-10-30 | Зе Риджентс Оф Зи Юнивесити Оф Кэлифонье | Пептид в качестве лекарственного средства и способ лечения патологий, связанных с воспалительными процессами, посредством пептида |
| US20080293639A1 (en) * | 2005-04-29 | 2008-11-27 | The Regents Of The University Of California | Peptides and peptide mimetics to treat pathologies characterized by an inflammatory response |
| GR1005428B (el) * | 2005-05-27 | 2007-02-01 | Χαραλαμπος Αλεξοπουλος | Συνθετικα λιποπεπτιδια με αντιαθηρογονο δραση, που εμποδιζουν την οξειδωση της λιποπρωτεϊνης χαμηλης πυκνοτητας (ldl) και αναστελλουν την απενεργοποιηση του ενζυμου της paf ακετυλοϋδρολασης (paf-ah) |
| GB0513096D0 (en) * | 2005-06-28 | 2005-08-03 | Strathclyde | Treatment of microbial infections |
| WO2007055873A2 (en) * | 2005-11-04 | 2007-05-18 | Avanir Pharmaceuticals | Process for the manufacture of peptide facilitators of reverse cholesterol transport |
| WO2007059372A2 (en) * | 2005-11-09 | 2007-05-24 | St. Jude Children's Research Hospital | Use of chloroquine to treat metabolic syndrome |
| US8163699B2 (en) * | 2006-06-01 | 2012-04-24 | Montreal Heart Institute | Method for the treatment of valvular disease |
| US20080227686A1 (en) * | 2006-06-16 | 2008-09-18 | Lipid Sciences, Inc. | Novel Peptides that Promote Lipid Efflux |
| EP2041174A2 (en) * | 2006-06-16 | 2009-04-01 | Lipid Sciences, Inc. | Novel peptides that promote lipid efflux |
| US20080206142A1 (en) * | 2006-06-16 | 2008-08-28 | Lipid Sciences, Inc. | Novel Peptides That Promote Lipid Efflux |
| EP2049137A4 (en) * | 2006-08-08 | 2013-05-01 | Univ California | SALICYLANILIDES AS AMPLIFIERS OF THE ORAL RELEASE OF THERAPEUTIC PEPTIDES |
| US20080138284A1 (en) * | 2006-09-26 | 2008-06-12 | Lipid Sciences, Inc. | Novel Peptides That Promote Lipid Efflux |
| CA2672131C (en) * | 2006-12-13 | 2016-06-07 | The Regents Of The University Of California | Potent and selective mediators of cholesterol efflux |
| US20080268038A1 (en) * | 2007-04-26 | 2008-10-30 | Wolfe Robert R | Compositions and Approaches for Increasing Diet Induced Thermogenesis, Inducing Weight Loss and Maintaining Muscle Mass and Strength |
| RU2010104042A (ru) * | 2007-07-09 | 2011-08-20 | Новартис АГ (CH) | Сохранение вторичной структуры пептида |
| AU2008296478B9 (en) | 2007-08-28 | 2015-03-19 | The Uab Research Foundation | Synthetic apolipoprotein E mimicking polypeptides and methods of use |
| JP2010537638A (ja) * | 2007-08-28 | 2010-12-09 | ユーエービー リサーチ ファウンデーション | 合成アポリポ蛋白質e模倣ポリペプチドおよび使用方法 |
| PT2193142E (pt) * | 2007-08-30 | 2015-04-22 | Curedm Group Holdings Llc | Composições e procedimentos de utilização de peptídeos pro-ilhota e seus análogos |
| JP2011506446A (ja) * | 2007-12-11 | 2011-03-03 | コーダ セラピューティクス, インコーポレイテッド | 損傷した創傷治癒組成物および治療 |
| US20110020242A1 (en) * | 2007-12-12 | 2011-01-27 | Gang Zheng | High-density lipoprotein-like peptide-phospholipid scaffold ("hpps") nanoparticles |
| US20100093624A1 (en) * | 2008-07-30 | 2010-04-15 | Cosmix Therapeutics Llc | Peptide therapeutics that bind vegf and methods of use thereof |
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| DK2396017T3 (en) * | 2009-02-16 | 2015-09-14 | Cerenis Therapeutics Holding Sa | Apolipoprotein A-I-mimetika |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7531514B2 (en) | 2000-08-24 | 2009-05-12 | The Regents Of The University Of California | Orally administered peptides synergize statin activity |
| US7579319B2 (en) | 2004-12-06 | 2009-08-25 | The Regents Of The University Of California | Methods for improving the structure and function of arterioles |
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