IL154530A0 - Process for production of biopterin compound - Google Patents
Process for production of biopterin compoundInfo
- Publication number
- IL154530A0 IL154530A0 IL15453001A IL15453001A IL154530A0 IL 154530 A0 IL154530 A0 IL 154530A0 IL 15453001 A IL15453001 A IL 15453001A IL 15453001 A IL15453001 A IL 15453001A IL 154530 A0 IL154530 A0 IL 154530A0
- Authority
- IL
- Israel
- Prior art keywords
- production
- biopterin compound
- present
- biopterin
- compound
- Prior art date
Links
- LHQIJBMDNUYRAM-UHFFFAOYSA-N L-erythro-Biopterin Natural products N1=C(N)NC(=O)C2=NC(C(O)C(O)C)=CN=C21 LHQIJBMDNUYRAM-UHFFFAOYSA-N 0.000 title abstract 3
- -1 biopterin compound Chemical class 0.000 title abstract 3
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- FNKQXYHWGSIFBK-RPDRRWSUSA-N sapropterin Chemical compound N1=C(N)NC(=O)C2=C1NC[C@H]([C@@H](O)[C@@H](O)C)N2 FNKQXYHWGSIFBK-RPDRRWSUSA-N 0.000 abstract 1
- 229960004617 sapropterin Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000262973 | 2000-08-31 | ||
| PCT/JP2001/007395 WO2002018587A1 (fr) | 2000-08-31 | 2001-08-28 | Procede de production de biopterines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL154530A0 true IL154530A0 (en) | 2003-09-17 |
Family
ID=18750574
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15453001A IL154530A0 (en) | 2000-08-31 | 2001-08-28 | Process for production of biopterin compound |
| IL154530A IL154530A (he) | 2000-08-31 | 2003-02-18 | תהליך להפקה של תרכובת ביופטרין ושימוש בתא שהשתנה בתהליך |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL154530A IL154530A (he) | 2000-08-31 | 2003-02-18 | תהליך להפקה של תרכובת ביופטרין ושימוש בתא שהשתנה בתהליך |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20040014167A1 (he) |
| EP (1) | EP1314782B1 (he) |
| JP (1) | JP4817590B2 (he) |
| KR (1) | KR100916163B1 (he) |
| CN (1) | CN1247778C (he) |
| AT (1) | ATE426021T1 (he) |
| AU (1) | AU2001280215B9 (he) |
| BR (1) | BR0113411A (he) |
| CA (1) | CA2420374A1 (he) |
| DE (1) | DE60138029D1 (he) |
| ES (1) | ES2320531T3 (he) |
| IL (2) | IL154530A0 (he) |
| WO (1) | WO2002018587A1 (he) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7442372B2 (en) | 2003-08-29 | 2008-10-28 | Biomarin Pharmaceutical Inc. | Delivery of therapeutic compounds to the brain and other tissues |
| DK1708690T3 (en) | 2003-11-17 | 2016-11-07 | Biomarin Pharm Inc | TREATMENT OF PHENYLKETONURI WITH BH4 |
| KR20070084270A (ko) * | 2004-11-17 | 2007-08-24 | 바이오마린 파머수티컬 인크. | 안정한 정제 제형물 |
| JPWO2006085535A1 (ja) * | 2005-02-09 | 2008-06-26 | 株式会社カネカ | テトラヒドロビオプテリン生合成酵素を用いたビオプテリン類の製造方法 |
| JP2010523708A (ja) | 2007-04-11 | 2010-07-15 | バイオマリン ファーマシューティカル インコーポレイテッド | テトラヒドロビオプテリンを投与する方法、関連する組成物および測定方法 |
| JP5084481B2 (ja) * | 2007-12-10 | 2012-11-28 | 花王株式会社 | 血圧調節剤のスクリーニング方法及び評価方法 |
| WO2009088530A1 (en) | 2008-01-03 | 2009-07-16 | Biomarin Pharmaceutical Inc. | Pterin analog for treating bh4 responsive condition |
| EP2240484A1 (en) | 2008-01-07 | 2010-10-20 | BioMarin Pharmaceutical Inc. | Method of synthesizing tetrahydrobiopterin |
| WO2012135389A2 (en) | 2011-03-28 | 2012-10-04 | The Regents Of The University Of California | Host cells and methods for oxidizing aromatic amino acids |
| KR101229912B1 (ko) * | 2011-04-06 | 2013-02-05 | 강원대학교산학협력단 | 재조합 대장균을 이용한 세피아프테린의 제조방법 |
| US9216178B2 (en) | 2011-11-02 | 2015-12-22 | Biomarin Pharmaceutical Inc. | Dry blend formulation of tetrahydrobiopterin |
| CN102516246B (zh) * | 2011-11-30 | 2014-08-06 | 安徽农业大学 | 一种从蚕体中提取纯化高纯度墨蝶呤的方法 |
| US20150024440A1 (en) * | 2012-02-29 | 2015-01-22 | Danmarks Tekniske Universitet | Microorganisms for the production of melatonin |
| WO2013127914A1 (en) * | 2012-02-29 | 2013-09-06 | Danmarks Tekniske Universitet | Microorganisms for the production of 5-hydroxytryptophan |
| CN102925476B (zh) * | 2012-11-15 | 2014-12-03 | 中国科学院上海巴斯德研究所 | 酵母中自组装的具有免疫原性的肠道病毒病毒样颗粒的制备方法及其应用 |
| CN103952367B (zh) * | 2013-04-16 | 2016-06-01 | 中国人民解放军军事医学科学院基础医学研究所 | 一种发酵培养基及利用其生产黑色素瘤治疗性质粒DNA疫苗pSVK-CAVA的方法 |
| US20160230200A1 (en) * | 2013-09-05 | 2016-08-11 | Danmarks Tekniske Universitet | Microorganisms for efficient production of melatonin and related compounds |
| EP3143153A4 (en) * | 2014-05-16 | 2018-01-03 | The University Of Georgia Research Foundation, Inc. | Microbial approach for the production of 5-hydroxytryptophan |
| WO2016109769A1 (en) * | 2015-01-02 | 2016-07-07 | Georgia Tech Research Corporation | Pterin-dependent biocatalysts and uses thereof |
| WO2017167866A1 (en) | 2016-03-31 | 2017-10-05 | Danmarks Tekniske Universitet | Optimized microbial cells for production of melatonin and other compounds |
| US10851365B2 (en) | 2016-03-31 | 2020-12-01 | Danmarks Tekniske Universitet | Optimized microbial cells for production of melatonin and other compounds |
| EP3464572B1 (en) | 2016-05-24 | 2023-07-26 | Danmarks Tekniske Universitet | Variants of acetylserotonin o-methyltransferase and uses thereof |
| US10767203B2 (en) | 2016-12-13 | 2020-09-08 | Danmarks Tekniske Universitet | Arylalkylamine N-acetyltransferase and uses thereof |
| WO2019175332A1 (en) | 2018-03-14 | 2019-09-19 | Imba - Institut Für Molekulare Biotechnologie Gmbh | Bh4 pathway inhibition and use thereof for treating t-cell mediated autoimmune diseases or hypersensitivity |
| WO2019175328A1 (en) | 2018-03-14 | 2019-09-19 | Imba - Institut Für Molekulare Biotechnologie Gmbh | Bh4pathwayactivationandusethereoffortreatingcancer |
| JP7553906B2 (ja) * | 2018-11-01 | 2024-09-19 | 宏 一瀬 | Sprをコードするポリヌクレオチドを含む組換えベクター、及びそれを含む組成物 |
| CA3132417A1 (en) | 2019-03-15 | 2020-09-24 | Danmarks Tekniske Universitet | Engineered cells for production of indole-derivatives |
| CN111073884A (zh) * | 2020-02-14 | 2020-04-28 | 昆明理工大学 | 提高非编码区域距离<50bp的SNP中具有功能效应的SNP位点检测准确率的方法 |
| CN111505179B (zh) * | 2020-04-07 | 2021-07-13 | 厦门大学 | 海洋水体中生物蝶呤的检测方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60178887A (ja) * | 1984-02-23 | 1985-09-12 | Kanegafuchi Chem Ind Co Ltd | 5,6,7,8−テトラヒドロ−l−ビオプテリンの製造法 |
| JPS619296A (ja) * | 1984-06-22 | 1986-01-16 | Kanegafuchi Chem Ind Co Ltd | 微生物によるl−エリスロ−ビオプテリンの製造法 |
| JPS6152296A (ja) * | 1984-08-21 | 1986-03-14 | Kanegafuchi Chem Ind Co Ltd | 微生物によるl−エリスロ−ビオプテリンの製造法 |
| JP2674707B2 (ja) * | 1988-06-22 | 1997-11-12 | 株式会社ビタミン研究所 | L‐ビオプテリンの製法 |
| EP0318926B1 (en) * | 1987-11-30 | 1995-05-03 | Kabushiki Kaisha Vitamin Kenkyusyo | Intermediates for synthesizing 5,6,7,8-tetrahydro-L-erythro-biopterin and its derivatives |
| JP2575781B2 (ja) * | 1988-02-29 | 1997-01-29 | 日清製粉株式会社 | 2,3−ジアシルオキシ−4−ヒドロキシ−トペンタナールおよびその製造方法 |
| JP3137333B2 (ja) * | 1990-07-21 | 2001-02-19 | サントリー株式会社 | テトラヒドロビオプテリンの製法およびそれに用いる酵素 |
| JP2754959B2 (ja) | 1991-07-24 | 1998-05-20 | 三菱電機株式会社 | 空気調和機のセンサ識別装置 |
| KR100456062B1 (ko) * | 2001-06-18 | 2004-11-08 | 박영식 | 재조합 대장균에 의한 테리딘 화합물의 제조방법 |
-
2001
- 2001-08-28 JP JP2002522494A patent/JP4817590B2/ja not_active Expired - Fee Related
- 2001-08-28 ES ES01958584T patent/ES2320531T3/es not_active Expired - Lifetime
- 2001-08-28 WO PCT/JP2001/007395 patent/WO2002018587A1/ja not_active Ceased
- 2001-08-28 IL IL15453001A patent/IL154530A0/xx active IP Right Grant
- 2001-08-28 EP EP01958584A patent/EP1314782B1/en not_active Expired - Lifetime
- 2001-08-28 AT AT01958584T patent/ATE426021T1/de active
- 2001-08-28 CN CNB018146325A patent/CN1247778C/zh not_active Expired - Fee Related
- 2001-08-28 KR KR1020037003005A patent/KR100916163B1/ko not_active Expired - Fee Related
- 2001-08-28 AU AU2001280215A patent/AU2001280215B9/en not_active Ceased
- 2001-08-28 BR BR0113411-6A patent/BR0113411A/pt not_active IP Right Cessation
- 2001-08-28 CA CA002420374A patent/CA2420374A1/en not_active Abandoned
- 2001-08-28 DE DE60138029T patent/DE60138029D1/de not_active Expired - Lifetime
- 2001-08-28 US US10/362,914 patent/US20040014167A1/en not_active Abandoned
-
2003
- 2003-02-18 IL IL154530A patent/IL154530A/he not_active IP Right Cessation
-
2005
- 2005-08-02 US US11/194,564 patent/US7807421B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE60138029D1 (de) | 2009-04-30 |
| CA2420374A1 (en) | 2003-02-24 |
| KR100916163B1 (ko) | 2009-09-08 |
| US7807421B2 (en) | 2010-10-05 |
| CN1247778C (zh) | 2006-03-29 |
| AU2001280215B9 (en) | 2007-03-22 |
| JPWO2002018587A1 (ja) | 2004-01-15 |
| CN1449442A (zh) | 2003-10-15 |
| EP1314782A1 (en) | 2003-05-28 |
| ES2320531T3 (es) | 2009-05-25 |
| WO2002018587A1 (fr) | 2002-03-07 |
| JP4817590B2 (ja) | 2011-11-16 |
| BR0113411A (pt) | 2004-01-06 |
| IL154530A (he) | 2011-02-28 |
| AU8021501A (en) | 2002-03-13 |
| ATE426021T1 (de) | 2009-04-15 |
| US20040014167A1 (en) | 2004-01-22 |
| AU2001280215B2 (en) | 2006-08-03 |
| EP1314782A4 (en) | 2005-01-12 |
| KR20030033042A (ko) | 2003-04-26 |
| EP1314782B1 (en) | 2009-03-18 |
| US20060008869A1 (en) | 2006-01-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted |