IL153224A0 - 1,4-dihydropyridines as bradykinin antagonists - Google Patents

1,4-dihydropyridines as bradykinin antagonists

Info

Publication number
IL153224A0
IL153224A0 IL15322401A IL15322401A IL153224A0 IL 153224 A0 IL153224 A0 IL 153224A0 IL 15322401 A IL15322401 A IL 15322401A IL 15322401 A IL15322401 A IL 15322401A IL 153224 A0 IL153224 A0 IL 153224A0
Authority
IL
Israel
Prior art keywords
dihydropyridines
bradykinin antagonists
bradykinin
antagonists
Prior art date
Application number
IL15322401A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL153224A0 publication Critical patent/IL153224A0/xx

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Pain & Pain Management (AREA)
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  • Cardiology (AREA)
  • Communicable Diseases (AREA)
  • Psychology (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
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  • Hospice & Palliative Care (AREA)
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IL15322401A 2000-08-10 2001-07-26 1,4-dihydropyridines as bradykinin antagonists IL153224A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22455800P 2000-08-10 2000-08-10
PCT/IB2001/001346 WO2002012235A1 (fr) 2000-08-10 2001-07-26 1,4-dihydropyridines utilises comme antagonistes de la bradykinine

Publications (1)

Publication Number Publication Date
IL153224A0 true IL153224A0 (en) 2003-07-06

Family

ID=22841188

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15322401A IL153224A0 (en) 2000-08-10 2001-07-26 1,4-dihydropyridines as bradykinin antagonists

Country Status (21)

Country Link
US (1) US6653313B2 (fr)
EP (1) EP1307449B1 (fr)
JP (1) JP2004505973A (fr)
AP (1) AP2001002238A0 (fr)
AR (1) AR034555A1 (fr)
AT (1) ATE312099T1 (fr)
AU (1) AU2001270947A1 (fr)
BR (1) BR0113071A (fr)
CA (1) CA2418908C (fr)
CR (1) CR6859A (fr)
DE (1) DE60115661T2 (fr)
ES (1) ES2257422T3 (fr)
GT (1) GT200100153A (fr)
IL (1) IL153224A0 (fr)
IS (1) IS6639A (fr)
MX (1) MXPA03001204A (fr)
PA (1) PA8525001A1 (fr)
PE (1) PE20020467A1 (fr)
SV (1) SV2003000588A (fr)
TN (1) TNSN01124A1 (fr)
WO (1) WO2002012235A1 (fr)

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JP5637710B2 (ja) * 2010-03-24 2014-12-10 株式会社トクヤマ ｛２−アミノ−１，４−ジヒドロ−６−メチル−４−（３−ニトロフェニル）−３，５−ピリジンジカルボン酸３−（１−ジフェニルメチルアゼチジン−３−イル）エステル５−イソプロピルエステル｝の製造方法
WO2013102145A1 (fr) 2011-12-28 2013-07-04 Global Blood Therapeutics, Inc. Composés d'aldéhydes hétéroaryles substitués et leurs procédés d'utilisation dans l'accroissement de l'oxygénation tissulaire
SI3141542T1 (sl) 2011-12-28 2020-11-30 Global Blood Therapeutics, Inc. Substituirane spojine benzaldehida in metode njihove uporabe pri povečanju oksigenacije tkiva
CN105073728A (zh) 2013-03-15 2015-11-18 全球血液疗法股份有限公司 化合物及其用于调节血红蛋白的用途
US9802900B2 (en) 2013-03-15 2017-10-31 Global Blood Therapeutics, Inc. Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin
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WO2014145040A1 (fr) 2013-03-15 2014-09-18 Global Blood Therapeutics, Inc. Composés aldéhydes substitués et leurs procédés d'utilisation pour accroître l'oxygénation tissulaire
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US9458139B2 (en) 2013-03-15 2016-10-04 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9604999B2 (en) 2013-03-15 2017-03-28 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
EP3060560A1 (fr) 2013-10-25 2016-08-31 Blueprint Medicines Corporation Inhibiteurs du récepteur du facteur de croissance des fibroblastes
EA202092627A1 (ru) 2013-11-18 2021-09-30 Глобал Блад Терапьютикс, Инк. Соединения и их применения для модуляции гемоглобина
EA028529B1 (ru) 2014-02-07 2017-11-30 Глобал Блад Терапьютикс, Инк. Кристаллические полиморфные формы свободного основания 2-гидрокси-6-((2-(1-изопропил-1н-пиразол-5-ил)пиридин-3-ил)метокси)бензальдегида
MA41841A (fr) 2015-03-30 2018-02-06 Global Blood Therapeutics Inc Composés aldéhyde pour le traitement de la fibrose pulmonaire, de l'hypoxie, et de maladies auto-immunes et des tissus conjonctifs
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TNSN97037A1 (fr) * 1996-02-19 2005-03-15 Pfizer Derives de 1,4 -dihydropyridine, procede pour leur preparation et compositions pharmaceutiques les contenant.
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JPH11106375A (ja) * 1997-08-18 1999-04-20 Pfizer Pharmaceut Inc ブラジキニンアンタゴニストとしての光学的に活性な１，４−ジヒドロピリジン化合物
ATE257479T1 (de) 1999-12-10 2004-01-15 Pfizer 5-ring heteroarylsubstituierte 1,4- dihydropyridine als bradykinin antagonisten
DE60001535T2 (de) 1999-12-10 2003-10-02 Pfizer Inc., New York Substituierte 1,4-Dihydropyridinverbindungen zur Verwendung als Bradykininantagonisten

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EP1307449A1 (fr) 2003-05-07
AP2001002238A0 (en) 2001-09-30
BR0113071A (pt) 2003-07-01
WO2002012235A1 (fr) 2002-02-14
CA2418908C (fr) 2006-05-09
CA2418908A1 (fr) 2002-02-14
JP2004505973A (ja) 2004-02-26
AR034555A1 (es) 2004-03-03
TNSN01124A1 (fr) 2005-11-10
ES2257422T3 (es) 2006-08-01
CR6859A (es) 2003-11-25
DE60115661D1 (de) 2006-01-12
IS6639A (is) 2002-11-28
EP1307449B1 (fr) 2005-12-07
AU2001270947A1 (en) 2002-02-18
US20020161006A1 (en) 2002-10-31
DE60115661T2 (de) 2006-08-24
SV2003000588A (es) 2003-01-13
ATE312099T1 (de) 2005-12-15
PE20020467A1 (es) 2002-06-14
MXPA03001204A (es) 2003-06-30
PA8525001A1 (es) 2002-08-26
GT200100153A (es) 2002-07-03

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