IL151715A0 - N-deacetylthiocolchicine derivatives and pharmaceutical compositions containing them - Google Patents
N-deacetylthiocolchicine derivatives and pharmaceutical compositions containing themInfo
- Publication number
- IL151715A0 IL151715A0 IL15171501A IL15171501A IL151715A0 IL 151715 A0 IL151715 A0 IL 151715A0 IL 15171501 A IL15171501 A IL 15171501A IL 15171501 A IL15171501 A IL 15171501A IL 151715 A0 IL151715 A0 IL 151715A0
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceutical compositions
- compositions containing
- deacetylthiocolchicine
- derivatives
- deacetylthiocolchicine derivatives
- Prior art date
Links
- NUNCOHUMTCDISK-AWEZNQCLSA-N (7s)-7-amino-1,2,3-trimethoxy-10-methylsulfanyl-6,7-dihydro-5h-benzo[a]heptalen-9-one Chemical class C1([C@@H](N)CC2)=CC(=O)C(SC)=CC=C1C1=C2C=C(OC)C(OC)=C1OC NUNCOHUMTCDISK-AWEZNQCLSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/40—Y being a hydrogen or a carbon atom
- C07C323/41—Y being a hydrogen or an acyclic carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/43—Y being a hetero atom
- C07C323/44—X or Y being nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2000MI000554A IT1318401B1 (it) | 2000-03-17 | 2000-03-17 | Derivati di n-desacetiltiocolchicina e composizioni farmaceutiche cheli contengono. |
| PCT/EP2001/002739 WO2001068597A1 (en) | 2000-03-17 | 2001-03-12 | N-deacetylthiocolchicine derivatives and pharmaceutical compositions containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL151715A0 true IL151715A0 (en) | 2003-04-10 |
Family
ID=11444502
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15171501A IL151715A0 (en) | 2000-03-17 | 2001-03-12 | N-deacetylthiocolchicine derivatives and pharmaceutical compositions containing them |
| IL151715A IL151715A (en) | 2000-03-17 | 2002-09-12 | History of N-de-acetylthiocolciccin and pharmaceutical preparations containing them |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL151715A IL151715A (en) | 2000-03-17 | 2002-09-12 | History of N-de-acetylthiocolciccin and pharmaceutical preparations containing them |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6627774B2 (cs) |
| EP (1) | EP1263719B1 (cs) |
| JP (1) | JP4614608B2 (cs) |
| KR (1) | KR100761577B1 (cs) |
| CN (1) | CN1169788C (cs) |
| AU (2) | AU4834101A (cs) |
| CA (1) | CA2403110C (cs) |
| CZ (1) | CZ303386B6 (cs) |
| DE (1) | DE60139306D1 (cs) |
| DK (1) | DK1263719T3 (cs) |
| ES (1) | ES2327386T3 (cs) |
| HU (1) | HU228790B1 (cs) |
| IL (2) | IL151715A0 (cs) |
| IT (1) | IT1318401B1 (cs) |
| NO (1) | NO329428B1 (cs) |
| PL (1) | PL201575B1 (cs) |
| PT (1) | PT1263719E (cs) |
| RU (1) | RU2257379C2 (cs) |
| SI (1) | SI1263719T1 (cs) |
| SK (1) | SK287108B6 (cs) |
| WO (1) | WO2001068597A1 (cs) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6825236B2 (en) * | 2003-04-14 | 2004-11-30 | California Pacific Medical Center | Colchicine derivatives |
| ITMI20040164A1 (it) | 2004-02-03 | 2004-05-03 | Indena Spa | Derivati di n.deacetiltiocolchicina loro uso e formulazioni farmaceutiche che li contengono |
| WO2006089207A2 (en) * | 2005-02-18 | 2006-08-24 | Abraxis Bioscience, Inc. | Drugs with improved hydrophobicity for incorporation in medical devices |
| CN105288630A (zh) * | 2005-02-18 | 2016-02-03 | 阿布拉科斯生物科学有限公司 | 治疗剂的组合和给予方式以及联合治疗 |
| MX2009002054A (es) * | 2006-08-31 | 2009-05-01 | Abraxis Bioscience Llc | Metodos para inhibir angiogenesis y tratamiento contra enfermedades asociadas con angiogenesis. |
| US20080280987A1 (en) * | 2006-08-31 | 2008-11-13 | Desai Neil P | Methods of inhibiting angiogenesis and treating angiogenesis-associated diseases |
| MX2011009452A (es) * | 2009-03-13 | 2011-11-29 | Abraxis Bioscience Llc | Terapia de combinacion con derivados tiocolchicina. |
| EP2924022A1 (en) * | 2014-03-27 | 2015-09-30 | INDENA S.p.A. | Amorphous form of a thiocolchicine derivative |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1359637A (fr) * | 1962-10-29 | 1964-04-30 | Roussel Uclaf | Dérivés de la cochicine et de la thiocolchicine et procédé de préparation |
| SU479288A3 (ru) * | 1966-12-27 | 1975-07-30 | Сумитомо Кемикал Компани Лтд (Фирма) | Способ получени серусодержащих амидов жирной кислоты |
| US4533675A (en) | 1984-04-17 | 1985-08-06 | The United States Of America As Represented By The Department Of Health And Human Services | Carbamates of colchicine for treatment of gout |
| DE68927479T2 (de) * | 1988-05-02 | 1997-04-03 | Phanos Tech Inc | Verbindungen, zusammensetzungen und verfahren zum binden von bio-affektions-substanzen an oberflächenmembranen von bioteilchen |
| US5433675A (en) * | 1993-11-29 | 1995-07-18 | Excelermatic Inc. | Traction roller transmission |
| IT1276996B1 (it) * | 1995-06-27 | 1997-11-04 | Indena Spa | Derivati della colchicina, loro uso e formulazioni che li contengono |
| IT1283110B1 (it) * | 1996-06-07 | 1998-04-07 | Indena Spa | Composti a scheletro colchicinico,loro uso come farmaci e composizioni che li contengono |
-
2000
- 2000-03-17 IT IT2000MI000554A patent/IT1318401B1/it active
-
2001
- 2001-03-12 CZ CZ20023083A patent/CZ303386B6/cs not_active IP Right Cessation
- 2001-03-12 DK DK01921326T patent/DK1263719T3/da active
- 2001-03-12 WO PCT/EP2001/002739 patent/WO2001068597A1/en not_active Ceased
- 2001-03-12 CN CNB018064833A patent/CN1169788C/zh not_active Expired - Lifetime
- 2001-03-12 IL IL15171501A patent/IL151715A0/xx active IP Right Grant
- 2001-03-12 AU AU4834101A patent/AU4834101A/xx active Pending
- 2001-03-12 EP EP01921326A patent/EP1263719B1/en not_active Expired - Lifetime
- 2001-03-12 DE DE60139306T patent/DE60139306D1/de not_active Expired - Lifetime
- 2001-03-12 ES ES01921326T patent/ES2327386T3/es not_active Expired - Lifetime
- 2001-03-12 JP JP2001567693A patent/JP4614608B2/ja not_active Expired - Lifetime
- 2001-03-12 CA CA002403110A patent/CA2403110C/en not_active Expired - Lifetime
- 2001-03-12 SK SK1310-2002A patent/SK287108B6/sk not_active IP Right Cessation
- 2001-03-12 SI SI200130931T patent/SI1263719T1/sl unknown
- 2001-03-12 KR KR1020027011947A patent/KR100761577B1/ko not_active Expired - Lifetime
- 2001-03-12 PT PT01921326T patent/PT1263719E/pt unknown
- 2001-03-12 RU RU2002124524/04A patent/RU2257379C2/ru active
- 2001-03-12 AU AU2001248341A patent/AU2001248341B2/en not_active Expired
- 2001-03-12 HU HU0300557A patent/HU228790B1/hu unknown
- 2001-03-12 PL PL357375A patent/PL201575B1/pl unknown
-
2002
- 2002-08-02 US US10/210,035 patent/US6627774B2/en not_active Expired - Lifetime
- 2002-09-12 NO NO20024354A patent/NO329428B1/no not_active IP Right Cessation
- 2002-09-12 IL IL151715A patent/IL151715A/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed |