IL150947A0 - Fluorescent detection method and reagent - Google Patents

Fluorescent detection method and reagent

Info

Publication number
IL150947A0
IL150947A0 IL15094701A IL15094701A IL150947A0 IL 150947 A0 IL150947 A0 IL 150947A0 IL 15094701 A IL15094701 A IL 15094701A IL 15094701 A IL15094701 A IL 15094701A IL 150947 A0 IL150947 A0 IL 150947A0
Authority
IL
Israel
Prior art keywords
reagent
group
detection method
fluorescent detection
nitroreductase
Prior art date
Application number
IL15094701A
Other languages
English (en)
Original Assignee
Amersham Biosciences Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amersham Biosciences Uk Ltd filed Critical Amersham Biosciences Uk Ltd
Publication of IL150947A0 publication Critical patent/IL150947A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • C09B23/08—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B67/00—Influencing the physical, e.g. the dyeing or printing properties of dyestuffs without chemical reactions, e.g. by treating with solvents grinding or grinding assistants, coating of pigments or dyes; Process features in the making of dyestuff preparations; Dyestuff preparations of a special physical nature, e.g. tablets, films
    • C09B67/0033—Blends of pigments; Mixtured crystals; Solid solutions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Materials By The Use Of Optical Means Adapted For Particular Applications (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
IL15094701A 2000-02-02 2001-02-01 Fluorescent detection method and reagent IL150947A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0002261.6A GB0002261D0 (en) 2000-02-02 2000-02-02 Fluorescent detection method & reagent
PCT/GB2001/000396 WO2001057237A2 (en) 2000-02-02 2001-02-01 Methods employing increased dye-fluorescence upon nitroreduction

Publications (1)

Publication Number Publication Date
IL150947A0 true IL150947A0 (en) 2003-02-12

Family

ID=9884728

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15094701A IL150947A0 (en) 2000-02-02 2001-02-01 Fluorescent detection method and reagent

Country Status (12)

Country Link
US (1) US7662973B2 (ja)
EP (2) EP1252520B1 (ja)
JP (2) JP3984475B2 (ja)
AT (1) ATE306669T1 (ja)
AU (2) AU782381B2 (ja)
CA (1) CA2399368C (ja)
DE (1) DE60115205T2 (ja)
DK (1) DK1252520T3 (ja)
ES (1) ES2250349T3 (ja)
GB (1) GB0002261D0 (ja)
IL (1) IL150947A0 (ja)
WO (1) WO2001057237A2 (ja)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4299131B2 (ja) * 2001-09-27 2009-07-22 富士フイルム株式会社 非対称シアニン色素
GB0123856D0 (en) * 2001-10-05 2001-11-28 Amersham Pharm Biotech Uk Ltd Method for determining cell cycle position
AU2003228418A1 (en) * 2002-03-29 2003-10-13 The General Hospital Corporation Nir-fluorescent cyanine dyes, their synthesis and biological use
FR2847161B1 (fr) * 2002-11-14 2005-01-07 Oreal Composition de teinture des fibres keratiniques contenant un precurseur de colorant et une enzyme a activite nitroreductase et procede mettant en oeuvre cette composition
WO2004043417A2 (en) * 2002-11-14 2004-05-27 L'oreal Composition for dyeing keratin fibres containing a dye precursor and an enzyme with nitroreductase activity
CA2555680A1 (en) * 2004-02-09 2005-08-18 Novozymes A/S Method for testing or screening for an enzyme of interest
CN1985171B (zh) * 2004-04-23 2012-08-08 通用电气医疗集团股份有限公司 荧光共振能量转移酶底物
GB0411993D0 (en) * 2004-05-28 2004-06-30 Amersham Biosciences Uk Ltd Method and reagent for measuring nitroreductase enzyme activity
EP1781675B1 (en) 2004-08-13 2014-03-26 Epoch Biosciences, Inc. Phosphonate fluorescent dyes and conjugates
US7767834B2 (en) * 2004-08-13 2010-08-03 Elitech Holding B.V. Phosphonylated fluorescent dyes and conjugates
EP1794237A2 (en) * 2004-09-30 2007-06-13 GE Healthcare UK Limited Fluorescent nucleotide analogues
GB0505777D0 (en) * 2005-03-22 2005-04-27 Amersham Biosciences Uk Ltd Enzyme detection method and reagent
ES2606333T3 (es) * 2005-11-28 2017-03-23 Dako Denmark A/S Colorantes de cianina y métodos para detectar una diana usando dichos colorantes
WO2008030120A1 (en) * 2006-09-07 2008-03-13 Auckland Uniservices Limited A method for the fluorescent detection of nitroreductase activity using nitro-substituted aromatic compounds
US20080226160A1 (en) * 2007-03-12 2008-09-18 Conversion Works, Inc. Systems and methods for filling light in frames during 2-d to 3-d image conversion
US7906106B2 (en) * 2007-06-27 2011-03-15 General Electric Company In vivo cell trafficking
US8021647B2 (en) * 2007-06-29 2011-09-20 General Electric Company In vivo optical imaging
EP2582793B1 (en) 2010-06-15 2017-09-06 Cellular Dynamics International, Inc. A compendium of ready-built stem cell models for interrogation of biological response
US8828678B2 (en) 2010-11-16 2014-09-09 Enzo Life Sciences, Inc. Self-immolative probes for enzyme activity detection
US20130040302A1 (en) 2011-07-11 2013-02-14 Thomas J. Burke Methods for cell reprogramming and genome engineering
CN102516793B (zh) * 2011-11-22 2014-02-05 大连理工大学 一类双苄基五甲川菁荧光染料、其制备方法及应用
WO2014132137A2 (en) 2013-03-01 2014-09-04 Université De Genève Transgenic cell selection
CN111033261A (zh) * 2017-06-27 2020-04-17 科里奥利医药研究有限责任公司 聚山梨醇酯的定量分析

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1004428A1 (ru) * 1981-12-30 1983-03-15 Предприятие П/Я Р-6496 4-Амино-N-пиразолилнафталимиды в качестве органических люминофоров желто-зеленого свечени
WO1993008288A1 (en) 1991-10-23 1993-04-29 Cancer Research Campaign Technology Limited Bacterial nitroreductase for the reduction of cb 1954 and analogues thereof to a cytotoxic form
US5534416A (en) * 1993-04-13 1996-07-09 Molecular Probes, Inc. Fluorescent viability assay using cyclic-substituted unsymmetrical cyanine dyes
US5658751A (en) 1993-04-13 1997-08-19 Molecular Probes, Inc. Substituted unsymmetrical cyanine dyes with selected permeability
EP0887700B1 (en) * 1997-06-24 2004-01-28 Eastman Kodak Company Sensitizing dyes for enhanced light absorption
EP1069911A1 (en) * 1998-04-06 2001-01-24 Dalhousie University A novel nitroreductase and therapeutic uses therefor
GB9812596D0 (en) * 1998-06-11 1998-08-12 Amersham Pharm Biotech Uk Ltd Energy transfer assay method

Also Published As

Publication number Publication date
JP3984475B2 (ja) 2007-10-03
WO2001057237A2 (en) 2001-08-09
ATE306669T1 (de) 2005-10-15
AU3037601A (en) 2001-08-14
DE60115205T2 (de) 2006-07-20
AU782381B2 (en) 2005-07-21
US20030186348A1 (en) 2003-10-02
DE60115205D1 (de) 2005-12-29
DK1252520T3 (da) 2006-02-06
EP1698900A1 (en) 2006-09-06
EP1252520A2 (en) 2002-10-30
CA2399368A1 (en) 2001-08-09
US7662973B2 (en) 2010-02-16
ES2250349T3 (es) 2006-04-16
JP2007183284A (ja) 2007-07-19
GB0002261D0 (en) 2000-03-22
EP1252520B1 (en) 2005-10-12
WO2001057237A3 (en) 2002-05-16
JP2003522333A (ja) 2003-07-22
AU2005222569A1 (en) 2005-11-10
CA2399368C (en) 2007-04-10

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