IL150763A0 - Jak/stat inhibitors and pharmaceutical compositions containing the same - Google Patents
Jak/stat inhibitors and pharmaceutical compositions containing the sameInfo
- Publication number
- IL150763A0 IL150763A0 IL15076301A IL15076301A IL150763A0 IL 150763 A0 IL150763 A0 IL 150763A0 IL 15076301 A IL15076301 A IL 15076301A IL 15076301 A IL15076301 A IL 15076301A IL 150763 A0 IL150763 A0 IL 150763A0
- Authority
- IL
- Israel
- Prior art keywords
- jak
- same
- jak3
- downregulate
- therapeutics
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/08—Antibacterial agents for leprosy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Marine Sciences & Fisheries (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Zoology (AREA)
- Communicable Diseases (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Transplantation (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17787200P | 2000-01-24 | 2000-01-24 | |
US72349000A | 2000-11-28 | 2000-11-28 | |
PCT/US2001/002033 WO2001052892A2 (en) | 2000-01-24 | 2001-01-22 | Jak/stat pathway inhibitors and the uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
IL150763A0 true IL150763A0 (en) | 2003-02-12 |
Family
ID=26873735
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15076301A IL150763A0 (en) | 2000-01-24 | 2001-01-22 | Jak/stat inhibitors and pharmaceutical compositions containing the same |
IL150763A IL150763A (en) | 2000-01-24 | 2002-07-16 | KAJ / TATS inhibitors and pharmaceutical preparations containing them |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL150763A IL150763A (en) | 2000-01-24 | 2002-07-16 | KAJ / TATS inhibitors and pharmaceutical preparations containing them |
Country Status (11)
Country | Link |
---|---|
US (2) | US20040209799A1 (ja) |
EP (1) | EP1250137B1 (ja) |
JP (2) | JP5512909B2 (ja) |
AT (1) | ATE369844T1 (ja) |
AU (1) | AU2968701A (ja) |
CA (1) | CA2397774A1 (ja) |
DE (1) | DE60129926T2 (ja) |
ES (1) | ES2452696T3 (ja) |
IL (2) | IL150763A0 (ja) |
PT (1) | PT1782800E (ja) |
WO (1) | WO2001052892A2 (ja) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1250137B1 (en) * | 2000-01-24 | 2007-08-15 | Genzyme Corporation | Jak/stat pathway inhibitors and the use thereof for the treatment of primary generalized osteoarthritis |
TWI329105B (en) | 2002-02-01 | 2010-08-21 | Rigel Pharmaceuticals Inc | 2,4-pyrimidinediamine compounds and their uses |
US20040175384A1 (en) * | 2003-12-12 | 2004-09-09 | Mohapatra Shyam S. | Protein kinase C as a target for the treatment of respiratory syncytial virus |
DK1656372T3 (da) | 2003-07-30 | 2013-07-01 | Rigel Pharmaceuticals Inc | 2,4-pyrimidindiaminforbindelser til anvendelse til behandling eller forebyggelse af autoimmunsygdomme |
US8592368B2 (en) * | 2003-12-19 | 2013-11-26 | University Of South Florida | JAK/STAT inhibitors and MAPK/ERK inhibitors for RSV infection |
KR101164541B1 (ko) * | 2004-01-12 | 2012-07-10 | 와이엠 바이오사이언시즈 오스트레일리아 피티와이 엘티디 | 선택적 키나제 저해제 |
WO2005100552A2 (en) * | 2004-04-12 | 2005-10-27 | Sanbio Inc. | Cells exhibiting neuronal progenitor cell characteristics |
WO2005102332A1 (ja) * | 2004-04-27 | 2005-11-03 | Santen Pharmaceutical Co., Ltd. | 変形性関節症治療剤 |
JP5225079B2 (ja) | 2005-06-08 | 2013-07-03 | ライジェル ファーマシューティカルズ, インコーポレイテッド | Jak経路の阻害のための組成物および方法 |
US20070203161A1 (en) | 2006-02-24 | 2007-08-30 | Rigel Pharmaceuticals, Inc. | Compositions and methods for inhibition of the jak pathway |
EP1734118A1 (en) * | 2005-06-15 | 2006-12-20 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Identification of JAK/STAT pathway modulating genes by genome wide RNAi screening |
EP1991532B1 (en) | 2006-02-24 | 2017-01-11 | Rigel Pharmaceuticals, Inc. | Compositions and methods for inhibition of the jak pathway |
WO2007120847A2 (en) | 2006-04-14 | 2007-10-25 | Massachusetts Institute Of Technology | Identifying and modulating molecular pathways that mediate nervous system plasticity |
EP2061446A2 (en) * | 2006-07-28 | 2009-05-27 | University Court of the University of Edinburgh | Use of cdk inhibitors for the treatment of granulocyte mediated disorders |
EP2265607B1 (en) | 2008-02-15 | 2016-12-14 | Rigel Pharmaceuticals, Inc. | Pyrimidine-2-amine compounds and their use as inhibitors of jak kinases |
US8138339B2 (en) | 2008-04-16 | 2012-03-20 | Portola Pharmaceuticals, Inc. | Inhibitors of protein kinases |
PT2323993E (pt) | 2008-04-16 | 2015-10-12 | Portola Pharm Inc | 2,6-diamino-pirimidina-5-il-carboxamidas como inibidores de quinasses syk ou jak |
WO2009131687A2 (en) | 2008-04-22 | 2009-10-29 | Portola Pharmaceuticals, Inc. | Inhibitors of protein kinases |
US9102625B2 (en) | 2010-11-01 | 2015-08-11 | Portola Pharmaceuticals, Inc. | Nicotinamides as JAK kinase modulators |
US20140112913A1 (en) * | 2011-02-10 | 2014-04-24 | Genqual Corporation | Methods of prognosing and administering treatment for inflammatory disorders |
MX363551B (es) | 2011-11-23 | 2019-03-27 | Portola Pharmaceuticals Inc Star | Compuestos derivados de pirazina como inhibidores de cinasa. |
WO2013077814A2 (en) * | 2011-11-25 | 2013-05-30 | Singapore Health Services Pte Ltd | Natural-killer/t-cell lymphoma (nktcl) susceptibility prediction, diagnosis and therapy |
WO2014058921A2 (en) | 2012-10-08 | 2014-04-17 | Portola Pharmaceuticals, Inc. | Substituted pyrimidinyl kinase inhibitors |
KR101632111B1 (ko) * | 2014-07-30 | 2016-06-20 | 원광대학교산학협력단 | 골다공증 예방 및 치료용 조성물 |
CA3129665A1 (en) | 2019-03-21 | 2020-09-24 | Onxeo | A dbait molecule in combination with kinase inhibitor for the treatment of cancer |
KR20220098759A (ko) | 2019-11-08 | 2022-07-12 | 인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) | 키나제 억제제에 대해 내성을 획득한 암의 치료 방법 |
WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5710158A (en) * | 1991-05-10 | 1998-01-20 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Aryl and heteroaryl quinazoline compounds which inhibit EGF and/or PDGF receptor tyrosine kinase |
JP3375131B2 (ja) * | 1992-02-24 | 2003-02-10 | スミスクライン・ビーチャム・コーポレイション | プロテインキナーゼc阻害剤 |
US5310759A (en) * | 1992-08-12 | 1994-05-10 | Bockman Richard S | Methods of protecting and preserving connective and support tissues |
ATE255582T1 (de) * | 1993-04-08 | 2003-12-15 | Univ Columbia | Verfahren zur synthese von 4-und/oder 5-(di) substituierten 2-aminoimidazolen aus 2- aminoimidazolen und aldehyden |
IL107736A (en) * | 1993-11-24 | 2001-01-11 | Yissum Res Dev Co | Pharmaceutical composition for the prevention of septic shock and for the treatment of chronic inflammatory diseases |
JP3714685B2 (ja) * | 1994-05-18 | 2005-11-09 | 第一サントリーファーマ株式会社 | ハイメニアルディシン及びその誘導体並びにそれらの合成中間体の製造法並びにその合成中間体 |
US5591740A (en) * | 1995-06-07 | 1997-01-07 | Osteoarthritis Sciences, Incorporated | Use of debromohymenialdisine for treating osteoarthritis |
DE69634900T2 (de) * | 1995-09-11 | 2006-05-18 | Osteoarthritis Sciences, Inc., Cambridge | Proteintyrosine-kinaseinhibitoren zur behandlung der osteoarthritis |
AU1050697A (en) * | 1995-11-09 | 1997-05-29 | Dana-Farber Cancer Institute | Methods for modulating t cell responses by manipulating a common cytokine receptor gamma chain |
CA2216559A1 (en) * | 1997-09-25 | 1999-03-25 | Michel Roberge | G2 checkpoint inhibitors and assay |
HUP0102492A2 (hu) * | 1998-06-19 | 2001-11-28 | Smithkline Beecham Corp. | Amino-indanon származékok alkalmazása NF-kB transzkripciós faktor inhibitor hatású gyógyszerkészítmények előállítására |
PA8474101A1 (es) * | 1998-06-19 | 2000-09-29 | Pfizer Prod Inc | Compuestos de pirrolo [2,3-d] pirimidina |
US6159694A (en) * | 1999-04-08 | 2000-12-12 | Isis Pharmaceuticals Inc. | Antisense modulation of stat3 expression |
DE69912808T2 (de) * | 1999-12-08 | 2004-09-30 | Centre National De La Recherche Scientifique (C.N.R.S.) | Verwendung von Hymenialdisin und dessen Derivaten zur Herstellung therapeutischer Mittel |
EP1250137B1 (en) * | 2000-01-24 | 2007-08-15 | Genzyme Corporation | Jak/stat pathway inhibitors and the use thereof for the treatment of primary generalized osteoarthritis |
-
2001
- 2001-01-22 EP EP01942563A patent/EP1250137B1/en not_active Expired - Lifetime
- 2001-01-22 ES ES06077137.5T patent/ES2452696T3/es not_active Expired - Lifetime
- 2001-01-22 JP JP2001552939A patent/JP5512909B2/ja not_active Expired - Lifetime
- 2001-01-22 PT PT60771375T patent/PT1782800E/pt unknown
- 2001-01-22 AT AT01942563T patent/ATE369844T1/de not_active IP Right Cessation
- 2001-01-22 CA CA002397774A patent/CA2397774A1/en not_active Abandoned
- 2001-01-22 IL IL15076301A patent/IL150763A0/xx unknown
- 2001-01-22 DE DE60129926T patent/DE60129926T2/de not_active Expired - Lifetime
- 2001-01-22 AU AU29687/01A patent/AU2968701A/en not_active Abandoned
- 2001-01-22 WO PCT/US2001/002033 patent/WO2001052892A2/en active IP Right Grant
-
2002
- 2002-07-16 IL IL150763A patent/IL150763A/en active IP Right Grant
-
2003
- 2003-02-21 US US10/372,917 patent/US20040209799A1/en not_active Abandoned
-
2007
- 2007-05-01 US US11/799,128 patent/US20090280081A1/en not_active Abandoned
-
2011
- 2011-10-11 JP JP2011224065A patent/JP5491474B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
PT1782800E (pt) | 2014-03-25 |
ES2452696T3 (es) | 2014-04-02 |
IL150763A (en) | 2010-06-16 |
US20090280081A1 (en) | 2009-11-12 |
JP5512909B2 (ja) | 2014-06-04 |
DE60129926D1 (de) | 2007-09-27 |
WO2001052892A2 (en) | 2001-07-26 |
JP5491474B2 (ja) | 2014-05-14 |
DE60129926T2 (de) | 2008-06-19 |
US20040209799A1 (en) | 2004-10-21 |
ATE369844T1 (de) | 2007-09-15 |
CA2397774A1 (en) | 2001-07-26 |
WO2001052892A3 (en) | 2002-01-24 |
EP1250137B1 (en) | 2007-08-15 |
AU2968701A (en) | 2001-07-31 |
EP1250137A2 (en) | 2002-10-23 |
JP2004500376A (ja) | 2004-01-08 |
JP2012041354A (ja) | 2012-03-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL150763A0 (en) | Jak/stat inhibitors and pharmaceutical compositions containing the same | |
AP1547A (en) | Antibodies to CD23, derivatives thereof, and their therapeutic uses. | |
TW200510328A (en) | 5-membered heterocycle-based p38 kinase inhibitors | |
EA199800772A1 (ru) | Производные 6-фенилпиридил-2-амина | |
EP1254899A3 (en) | Piperazine derivatives and their use as anti-inflammatory agents | |
AU2002256359A1 (en) | Antisense and anti-inflammatory based compositions to treat respiratory disorders | |
MY129406A (en) | Taste masked liquid pharmaceutical compositions | |
MXPA04006614A (es) | Deazapurinas y usos de las mismas. | |
RS20050070A (en) | Use of 1kb kinase inhibitors for the treatment of pain | |
YU53899A (sh) | Primena inhibitora ciklooksigenaze-2 u prevenciji kardiovaskularnih poremećaja | |
BR0113286B1 (pt) | pirazàis substituÍdos e composiÇço farmacÊutica compreendendo os mesmos. | |
SG124234A1 (en) | Cell adhesion inhibitors | |
MXPA05005223A (es) | Diaminotriazoles utiles como inhibidores de proteinas cinasas. | |
PL351125A1 (en) | Derivatives of 4,5-diaryl-3(2)-furanone as inhibitors of cykoxygenease-2 | |
MXPA04003668A (es) | Inhibidores de fosfodiesteresa de tipo 4 y usos de los mismos. | |
IL151320A0 (en) | Pharmaceutical compositions of glycogen phosphorylase inhibitors | |
AU5186799A (en) | Peptides of il-2 and derivatives thereof and their use as therapeutic agents | |
AU3227700A (en) | Skin sanitizing compositions | |
PT1032414E (pt) | Combinacao de um inibidor da enzima de conversao da angiotensina e de um diuretico para o tratamento de perturbacoes microcirculatorias | |
GB2340751B (en) | Pharmaceutical compositions | |
EA200000165A1 (ru) | Разветвленные алкоксизамещенные-2-аминопиридины в качестве ингибиторов nos | |
SI1622939T1 (sl) | Akrivne variante il-18 vezavnega proteina in medicinske uporabe le-tega | |
AU4179399A (en) | Use of nmda antagonists and/or sodium channel antagonists for the treatment of inflammatory disorders | |
IL126998A (en) | Potassium, sodium or tris oxaprozin salt pharmaceutical formulations | |
EP1875900A3 (en) | JAK/STAT pathway inhibitors and the use thereof for the treatment of osteoarthritis |