IL150541A0 - Calcium dicarboxylate ethers, methods of making same, and treatment of vascular disease and diabetes therewith - Google Patents

Calcium dicarboxylate ethers, methods of making same, and treatment of vascular disease and diabetes therewith

Info

Publication number
IL150541A0
IL150541A0 IL15054101A IL15054101A IL150541A0 IL 150541 A0 IL150541 A0 IL 150541A0 IL 15054101 A IL15054101 A IL 15054101A IL 15054101 A IL15054101 A IL 15054101A IL 150541 A0 IL150541 A0 IL 150541A0
Authority
IL
Israel
Prior art keywords
treatment
methods
vascular disease
making same
diabetes
Prior art date
Application number
IL15054101A
Other languages
English (en)
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of IL150541A0 publication Critical patent/IL150541A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/125Saturated compounds having only one carboxyl group and containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235Saturated compounds containing more than one carboxyl group
    • C07C59/305Saturated compounds containing more than one carboxyl group containing ether groups, groups, groups, or groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
IL15054101A 2000-01-25 2001-01-11 Calcium dicarboxylate ethers, methods of making same, and treatment of vascular disease and diabetes therewith IL150541A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17782300P 2000-01-25 2000-01-25
PCT/IB2001/000026 WO2001055078A1 (en) 2000-01-25 2001-01-11 Calcium dicarboxylate ethers, methods of making same, and treatment of vascular disease and diabetes therewith

Publications (1)

Publication Number Publication Date
IL150541A0 true IL150541A0 (en) 2003-02-12

Family

ID=22650106

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15054101A IL150541A0 (en) 2000-01-25 2001-01-11 Calcium dicarboxylate ethers, methods of making same, and treatment of vascular disease and diabetes therewith

Country Status (39)

Country Link
EP (1) EP1259474B1 (zh)
JP (1) JP4750995B2 (zh)
KR (1) KR20020073182A (zh)
CN (1) CN1395555A (zh)
AP (1) AP2002002587A0 (zh)
AR (1) AR029436A1 (zh)
AT (1) ATE431326T1 (zh)
AU (1) AU2214001A (zh)
BG (1) BG106851A (zh)
BR (1) BR0107763A (zh)
CA (1) CA2397960C (zh)
CO (1) CO5261537A1 (zh)
CZ (1) CZ20022474A3 (zh)
DE (1) DE60138686D1 (zh)
DK (1) DK1259474T3 (zh)
DZ (1) DZ3239A1 (zh)
EA (1) EA004862B1 (zh)
EE (1) EE200200404A (zh)
ES (1) ES2324281T3 (zh)
GE (1) GEP20053428B (zh)
GT (1) GT200100015A (zh)
HN (1) HN2001000011A (zh)
HU (1) HUP0204422A3 (zh)
IL (1) IL150541A0 (zh)
IS (1) IS6442A (zh)
MA (1) MA26867A1 (zh)
MX (1) MXPA02007223A (zh)
NO (1) NO20023526L (zh)
NZ (1) NZ519550A (zh)
OA (1) OA12166A (zh)
PA (1) PA8510601A1 (zh)
PE (1) PE20011064A1 (zh)
PL (1) PL357076A1 (zh)
SK (1) SK10622002A3 (zh)
SV (1) SV2002000290A (zh)
TN (1) TNSN01013A1 (zh)
UY (1) UY26550A1 (zh)
WO (1) WO2001055078A1 (zh)
ZA (1) ZA200205880B (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1481962A1 (en) * 1997-12-12 2004-12-01 Warner-Lambert Company LLC New cholesterolemia-lowering carboxyalkylether compound
AU2003255937A1 (en) * 2002-08-22 2004-03-11 Warner-Lambert Company Llc Method of treating osteoarthritis
US7816405B2 (en) 2005-04-19 2010-10-19 Eisai R&D Management Co., Ltd. Calcium bis [(2S)-3-[3-[(2S)-3-(4-chloro-2-cyanophenoxy)-2-fluoropropoxy]phenyl ]-2-isopropoxypropionate] and intermediate thereof
WO2006115130A1 (ja) * 2005-04-19 2006-11-02 Eisai R & D Management Co., Ltd. ビス[(2s)-3-[3-[(2s)-3-(4-クロロ-2-シアノフェノキシ)-2-フルオロプロポキシ]フェニル]-2-イソプロポキシプロピオン酸]カルシウム及びその中間体
SG10201912713YA (en) * 2014-11-14 2020-02-27 Gemphire Therapeutics Inc PROCESSES AND INTERMEDIATES FOR PREPARING α,ω-DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS
CA3059073A1 (en) * 2017-04-18 2018-10-25 Daniela Carmen Oniciu Gemcabene, pharmaceutically acceptable salts thereof, compositions thereof and methods of use therefor
JP2022505033A (ja) * 2018-10-18 2022-01-14 ジェムフィアー セラピューティクス インコーポレイテッド ゲムカベン、薬学的に許容されるその塩、その組成物、およびその使用方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648387A (en) 1995-03-24 1997-07-15 Warner-Lambert Company Carboxyalkylethers, formulations, and treatment of vascular diseases
NZ503982A (en) 1997-12-12 2002-03-28 Warner Lambert Co Statin-carboxyalkylether combinations useful for treating vascular disorders and diabetes mellitus

Also Published As

Publication number Publication date
GEP20053428B (en) 2005-01-25
MXPA02007223A (es) 2002-11-29
EA004862B1 (ru) 2004-08-26
OA12166A (en) 2003-11-07
HUP0204422A3 (en) 2003-08-28
JP2003520835A (ja) 2003-07-08
HUP0204422A2 (en) 2003-05-28
CA2397960C (en) 2008-09-09
IS6442A (is) 2002-06-25
PL357076A1 (en) 2004-07-12
PA8510601A1 (es) 2002-08-26
KR20020073182A (ko) 2002-09-19
NO20023526L (no) 2002-08-27
UY26550A1 (es) 2001-08-27
TNSN01013A1 (fr) 2005-11-10
WO2001055078A1 (en) 2001-08-02
AP2002002587A0 (en) 2002-09-30
BR0107763A (pt) 2002-11-12
DZ3239A1 (fr) 2001-08-02
PE20011064A1 (es) 2001-10-22
EP1259474B1 (en) 2009-05-13
ATE431326T1 (de) 2009-05-15
CN1395555A (zh) 2003-02-05
AR029436A1 (es) 2003-06-25
BG106851A (en) 2003-01-31
NZ519550A (en) 2003-11-28
SV2002000290A (es) 2002-07-16
EE200200404A (et) 2003-10-15
CA2397960A1 (en) 2001-08-02
GT200100015A (es) 2001-10-19
CO5261537A1 (es) 2003-03-31
CZ20022474A3 (cs) 2003-06-18
ZA200205880B (en) 2003-07-23
DK1259474T3 (da) 2009-07-20
EP1259474A1 (en) 2002-11-27
JP4750995B2 (ja) 2011-08-17
NO20023526D0 (no) 2002-07-24
AU2214001A (en) 2001-08-07
DE60138686D1 (de) 2009-06-25
MA26867A1 (fr) 2004-12-20
ES2324281T3 (es) 2009-08-04
EA200200641A1 (ru) 2002-12-26
HN2001000011A (es) 2001-06-13
SK10622002A3 (sk) 2003-07-01

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