IL149142A0 - Ligand activated transcriptional regulator proteins - Google Patents

Ligand activated transcriptional regulator proteins

Info

Publication number
IL149142A0
IL149142A0 IL14914200A IL14914200A IL149142A0 IL 149142 A0 IL149142 A0 IL 149142A0 IL 14914200 A IL14914200 A IL 14914200A IL 14914200 A IL14914200 A IL 14914200A IL 149142 A0 IL149142 A0 IL 149142A0
Authority
IL
Israel
Prior art keywords
transcriptional regulator
regulator proteins
ligand activated
activated transcriptional
ligand
Prior art date
Application number
IL14914200A
Other languages
English (en)
Original Assignee
Novartis Ag
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag, Scripps Research Inst filed Critical Novartis Ag
Publication of IL149142A0 publication Critical patent/IL149142A0/xx

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70567Nuclear receptors, e.g. retinoic acid receptor [RAR], RXR, nuclear orphan receptors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/721Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL14914200A 1999-10-25 2000-10-23 Ligand activated transcriptional regulator proteins IL149142A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US43304299A 1999-10-25 1999-10-25
US09/586,625 US7329728B1 (en) 1999-10-25 2000-06-02 Ligand activated transcriptional regulator proteins
PCT/EP2000/010430 WO2001030843A1 (en) 1999-10-25 2000-10-23 Ligand activated transcriptional regulator proteins

Publications (1)

Publication Number Publication Date
IL149142A0 true IL149142A0 (en) 2002-11-10

Family

ID=27029724

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14914200A IL149142A0 (en) 1999-10-25 2000-10-23 Ligand activated transcriptional regulator proteins
IL149142A IL149142A (en) 1999-10-25 2002-04-15 Ligand activated transcriptional regulator fusion protein, nucleic acid molecule encoding the same and use thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL149142A IL149142A (en) 1999-10-25 2002-04-15 Ligand activated transcriptional regulator fusion protein, nucleic acid molecule encoding the same and use thereof

Country Status (8)

Country Link
US (3) US7329728B1 (cg-RX-API-DMAC7.html)
EP (1) EP1226168A1 (cg-RX-API-DMAC7.html)
JP (2) JP2003512827A (cg-RX-API-DMAC7.html)
AU (1) AU775988B2 (cg-RX-API-DMAC7.html)
CA (1) CA2388535A1 (cg-RX-API-DMAC7.html)
IL (2) IL149142A0 (cg-RX-API-DMAC7.html)
NZ (1) NZ518218A (cg-RX-API-DMAC7.html)
WO (1) WO2001030843A1 (cg-RX-API-DMAC7.html)

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US10801017B2 (en) 2011-11-30 2020-10-13 The Broad Institute, Inc. Nucleotide-specific recognition sequences for designer TAL effectors
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Also Published As

Publication number Publication date
US20080318839A1 (en) 2008-12-25
IL149142A (en) 2010-05-31
CA2388535A1 (en) 2001-05-03
US7442784B2 (en) 2008-10-28
US20030186841A1 (en) 2003-10-02
WO2001030843A9 (en) 2002-09-19
NZ518218A (en) 2004-04-30
AU775988B2 (en) 2004-08-19
US7329728B1 (en) 2008-02-12
WO2001030843A1 (en) 2001-05-03
AU1143801A (en) 2001-05-08
JP2003512827A (ja) 2003-04-08
JP2009273463A (ja) 2009-11-26
EP1226168A1 (en) 2002-07-31

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