IL149051A0 - Pyrazolo [1,5,-d] [1,2,4] triazines for enhancing cognition - Google Patents

Pyrazolo [1,5,-d] [1,2,4] triazines for enhancing cognition

Info

Publication number
IL149051A0
IL149051A0 IL14905100A IL14905100A IL149051A0 IL 149051 A0 IL149051 A0 IL 149051A0 IL 14905100 A IL14905100 A IL 14905100A IL 14905100 A IL14905100 A IL 14905100A IL 149051 A0 IL149051 A0 IL 149051A0
Authority
IL
Israel
Prior art keywords
triazines
pyrazolo
enhancing cognition
cognition
enhancing
Prior art date
Application number
IL14905100A
Other languages
English (en)
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9927874.9A external-priority patent/GB9927874D0/en
Priority claimed from GB0009602A external-priority patent/GB0009602D0/en
Priority claimed from GB0018651A external-priority patent/GB0018651D0/en
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of IL149051A0 publication Critical patent/IL149051A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL14905100A 1999-11-25 2000-11-22 Pyrazolo [1,5,-d] [1,2,4] triazines for enhancing cognition IL149051A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9927874.9A GB9927874D0 (en) 1999-11-25 1999-11-25 Therapeutic agents
GB0009602A GB0009602D0 (en) 2000-04-18 2000-04-18 Therapeutic agents
GB0018651A GB0018651D0 (en) 2000-07-28 2000-07-28 Therapeutic agents
PCT/GB2000/004450 WO2001038331A2 (fr) 1999-11-25 2000-11-22 Groupe pyrazolo[1,5-d][1,2,4]triazines destine a ameliorer la cognition

Publications (1)

Publication Number Publication Date
IL149051A0 true IL149051A0 (en) 2002-11-10

Family

ID=27255677

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14905100A IL149051A0 (en) 1999-11-25 2000-11-22 Pyrazolo [1,5,-d] [1,2,4] triazines for enhancing cognition

Country Status (20)

Country Link
US (1) US6355638B1 (fr)
EP (1) EP1235829A2 (fr)
JP (1) JP2003514909A (fr)
KR (1) KR20020053091A (fr)
CN (1) CN1391574A (fr)
AU (1) AU1533001A (fr)
BG (1) BG106734A (fr)
BR (1) BR0015126A (fr)
CA (1) CA2391103A1 (fr)
CZ (1) CZ20021813A3 (fr)
EA (1) EA200200599A1 (fr)
EE (1) EE200200260A (fr)
HK (1) HK1046406A1 (fr)
HU (1) HUP0203579A3 (fr)
IL (1) IL149051A0 (fr)
MX (1) MXPA02005233A (fr)
NO (1) NO20022456L (fr)
PL (1) PL355637A1 (fr)
SK (1) SK8952002A3 (fr)
WO (1) WO2001038331A2 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0128499D0 (en) * 2001-11-28 2002-01-23 Merck Sharp & Dohme Therapeutic agents
EP2298296A1 (fr) * 2009-08-25 2011-03-23 CNRS Centre National De La Recherche Scientifique Composition et procédé pour le traitement de troubles cognitifs chez des sujets atteints du syndrome de Down
CN103038229B (zh) * 2010-05-26 2016-05-11 桑诺维恩药品公司 杂芳基化合物及其使用方法
US20150374705A1 (en) 2012-02-14 2015-12-31 Shanghai Institues for Biological Sciences Substances for treatment or relief of pain
CN107344938B (zh) * 2016-05-06 2022-05-06 上海赛默罗生物科技有限公司 吡唑-三嗪类衍生物、其制备方法、药物组合物和用途
CN107344936B (zh) * 2016-05-06 2022-06-03 上海赛默罗生物科技有限公司 三唑哒嗪类衍生物、其制备方法、药物组合物和用途
KR20220048489A (ko) * 2019-06-19 2022-04-19 바이오마린 파머수티컬 인크. 질환의 치료를 위한 글리콜레이트 산화효소 억제제

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998004559A2 (fr) * 1996-07-25 1998-02-05 Merck Sharp & Dohme Limited Derives de triazolo-pyridazine substitues servant de ligands pour recepteurs de gaba
GB9715977D0 (en) * 1997-07-29 1997-10-01 Merck Sharp & Dohme Therapeutic agents
JP2002509150A (ja) * 1998-01-14 2002-03-26 メルク シャープ エンド ドーム リミテッド Ｇａｂａ受容体のリガンドとしてのトリアゾロピリダジン誘導体
GB9806102D0 (en) * 1998-03-20 1998-05-20 Merck Sharp & Dohme Therapeutic agents
EP1087968A1 (fr) * 1998-06-16 2001-04-04 MERCK SHARP & DOHME LTD. Derives de triazolo-pyridine comme ligands de recepteurs de gaba
JP2002527519A (ja) * 1998-10-16 2002-08-27 メルク シャープ エンド ドーム リミテッド Ｇａｂａ受容体のリガンドとしてのピラゾロトリアジン誘導体

Also Published As

Publication number Publication date
EA200200599A1 (ru) 2002-12-26
PL355637A1 (en) 2004-05-04
NO20022456D0 (no) 2002-05-24
CN1391574A (zh) 2003-01-15
MXPA02005233A (es) 2002-11-07
EP1235829A2 (fr) 2002-09-04
KR20020053091A (ko) 2002-07-04
AU1533001A (en) 2001-06-04
WO2001038331A3 (fr) 2001-11-08
CA2391103A1 (fr) 2001-05-31
SK8952002A3 (en) 2002-10-08
HK1046406A1 (zh) 2003-01-10
HUP0203579A3 (en) 2003-07-28
BR0015126A (pt) 2002-07-02
WO2001038331A2 (fr) 2001-05-31
HUP0203579A2 (hu) 2003-03-28
NO20022456L (no) 2002-05-24
JP2003514909A (ja) 2003-04-22
BG106734A (en) 2003-02-28
EE200200260A (et) 2003-06-16
US6355638B1 (en) 2002-03-12
CZ20021813A3 (cs) 2002-08-14

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