IL148678A0 - Dna sequencing method - Google Patents

Dna sequencing method

Info

Publication number
IL148678A0
IL148678A0 IL14867800A IL14867800A IL148678A0 IL 148678 A0 IL148678 A0 IL 148678A0 IL 14867800 A IL14867800 A IL 14867800A IL 14867800 A IL14867800 A IL 14867800A IL 148678 A0 IL148678 A0 IL 148678A0
Authority
IL
Israel
Prior art keywords
dna sequencing
sequencing method
polynucleotide
enzyme
detection
Prior art date
Application number
IL14867800A
Other languages
English (en)
Original Assignee
Medical Biosystems Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Biosystems Ltd filed Critical Medical Biosystems Ltd
Publication of IL148678A0 publication Critical patent/IL148678A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
IL14867800A 1999-10-06 2000-10-06 Dna sequencing method IL148678A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9923644.0A GB9923644D0 (en) 1999-10-06 1999-10-06 DNA sequencing
PCT/GB2000/003860 WO2001025480A2 (en) 1999-10-06 2000-10-06 Dna sequencing method

Publications (1)

Publication Number Publication Date
IL148678A0 true IL148678A0 (en) 2002-09-12

Family

ID=10862234

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14867800A IL148678A0 (en) 1999-10-06 2000-10-06 Dna sequencing method
IL148678A IL148678A (en) 1999-10-06 2002-03-13 A method for sequencing DNA sequences

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL148678A IL148678A (en) 1999-10-06 2002-03-13 A method for sequencing DNA sequences

Country Status (21)

Country Link
US (4) US20050214849A1 (de)
EP (1) EP1226271B1 (de)
JP (2) JP5030249B2 (de)
KR (1) KR100809171B1 (de)
CN (1) CN1159457C (de)
AT (1) ATE388242T1 (de)
AU (1) AU769102B2 (de)
BR (1) BR0014468A (de)
CA (1) CA2386115C (de)
DE (1) DE60038244T2 (de)
DK (1) DK1226271T3 (de)
EA (1) EA006702B1 (de)
ES (1) ES2302497T3 (de)
GB (1) GB9923644D0 (de)
HK (1) HK1045857A1 (de)
IL (2) IL148678A0 (de)
IS (1) IS6333A (de)
MX (1) MXPA02003534A (de)
NZ (1) NZ517775A (de)
PT (1) PT1226271E (de)
WO (1) WO2001025480A2 (de)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100664331B1 (ko) * 1997-07-28 2007-01-02 메디칼 바이오시스템스 리미티드 핵산 서열 분석
US7875440B2 (en) 1998-05-01 2011-01-25 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US6780591B2 (en) 1998-05-01 2004-08-24 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
GB9907812D0 (en) * 1999-04-06 1999-06-02 Medical Biosystems Ltd Sequencing
US7056661B2 (en) 1999-05-19 2006-06-06 Cornell Research Foundation, Inc. Method for sequencing nucleic acid molecules
EP1681356B1 (de) 1999-05-19 2011-10-19 Cornell Research Foundation, Inc. Methode zur Nukleinsäurensequenzierung
GB9923644D0 (en) 1999-10-06 1999-12-08 Medical Biosystems Ltd DNA sequencing
DE60131194T2 (de) 2000-07-07 2008-08-07 Visigen Biotechnologies, Inc., Bellaire Sequenzbestimmung in echtzeit
AU2002227156A1 (en) 2000-12-01 2002-06-11 Visigen Biotechnologies, Inc. Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity
GB0112238D0 (en) * 2001-05-18 2001-07-11 Medical Biosystems Ltd Sequencing method
US6902921B2 (en) 2001-10-30 2005-06-07 454 Corporation Sulfurylase-luciferase fusion proteins and thermostable sulfurylase
US6956114B2 (en) 2001-10-30 2005-10-18 '454 Corporation Sulfurylase-luciferase fusion proteins and thermostable sulfurylase
SE0201655D0 (sv) * 2002-05-31 2002-05-31 Amersham Biosciences Ab A method of electrophoresis
AU2004257918B2 (en) * 2003-07-15 2008-07-03 Daniel Henry Densham Measurement of a polynucleotide amplification reaction
GB0317343D0 (en) * 2003-07-24 2003-08-27 Medical Biosystems Ltd Polynucleotide sequencing
US7169560B2 (en) 2003-11-12 2007-01-30 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
WO2005080605A2 (en) 2004-02-19 2005-09-01 Helicos Biosciences Corporation Methods and kits for analyzing polynucleotide sequences
US7170050B2 (en) 2004-09-17 2007-01-30 Pacific Biosciences Of California, Inc. Apparatus and methods for optical analysis of molecules
US7666593B2 (en) 2005-08-26 2010-02-23 Helicos Biosciences Corporation Single molecule sequencing of captured nucleic acids
CN101460953B (zh) * 2006-03-31 2012-05-30 索雷克萨公司 用于合成分析的序列的系统和装置
GB0721340D0 (en) * 2007-10-30 2007-12-12 Isis Innovation Polymerase-based single-molecule DNA sequencing
BRPI0909212A2 (pt) 2008-03-28 2015-08-18 Pacific Biosciences California Composições e método para sequeciamento de ácido nucléico
US9182406B2 (en) 2008-08-04 2015-11-10 Biodesy, Inc. Nonlinear optical detection of molecules comprising an unnatural amino acid possessing a hyperpolarizability
CN102317471A (zh) * 2008-12-11 2012-01-11 加利福尼亚大学董事会 用于单个dna分子的直接测序的方法和系统
US8911972B2 (en) 2009-12-16 2014-12-16 Pacific Biosciences Of California, Inc. Sequencing methods using enzyme conformation
WO2011159942A1 (en) * 2010-06-18 2011-12-22 Illumina, Inc. Conformational probes and methods for sequencing nucleic acids
GB2503604B (en) 2011-03-21 2020-04-22 Biodesy Llc Classification of kinase inhibitors using second harmonic optical techniques
DE102013202721A1 (de) * 2013-02-20 2014-08-21 Siemens Aktiengesellschaft Sequenziervorrichtung zum Sequenzieren mindestens eines Nukleinsäureeinzelstrangs und Verfahren zum Sequenzieren mindestens eines Nukleinsäureeinzelstrangs
GB201306444D0 (en) * 2013-04-09 2013-05-22 Base4 Innovation Ltd Single nucleotide detection method
PL3169805T3 (pl) * 2014-07-15 2019-01-31 Illumina, Inc. Aktywowane biochemicznie urządzenie elektroniczne
WO2016106286A1 (en) 2014-12-23 2016-06-30 Biodesy, Inc. Attachment of proteins to interfaces for use in nonlinear optical detection
US10077470B2 (en) 2015-07-21 2018-09-18 Omniome, Inc. Nucleic acid sequencing methods and systems
CA3021769C (en) 2016-04-29 2021-11-23 Omniome, Inc. Sequencing method employing ternary complex destabilization to identify cognate nucleotides
AU2017313718B2 (en) 2016-08-15 2023-09-14 Pacific Biosciences Of California, Inc. Method and system for sequencing nucleic acids
US10428378B2 (en) 2016-08-15 2019-10-01 Omniome, Inc. Sequencing method for rapid identification and processing of cognate nucleotide pairs
EP3562962B1 (de) 2016-12-30 2022-01-05 Omniome, Inc. Verfahren und system unter verwendung von unterscheidbaren polymerasen zum nachweis von ternären komplexen und zur identifizierung von verwandten nukleotiden
CA3050695C (en) 2017-01-20 2024-02-20 Omniome, Inc. Process for cognate nucleotide detection in a nucleic acid sequencing workflow
US9951385B1 (en) 2017-04-25 2018-04-24 Omniome, Inc. Methods and apparatus that increase sequencing-by-binding efficiency
US10161003B2 (en) 2017-04-25 2018-12-25 Omniome, Inc. Methods and apparatus that increase sequencing-by-binding efficiency
CA3232118A1 (en) * 2017-09-15 2019-03-21 Illumina, Inc. Sequence-detection system
WO2019079593A1 (en) 2017-10-19 2019-04-25 Omniome, Inc. BACKGROUND NOISE REDUCTION AND STABILIZATION OF SIMULTANEOUS COMPLEXES IN LINKED ASSAY WORKFLOWS
US10273528B1 (en) 2017-11-17 2019-04-30 Ultima Genomics, Inc. Methods and systems for analyte detection and analysis
US11499962B2 (en) 2017-11-17 2022-11-15 Ultima Genomics, Inc. Methods and systems for analyte detection and analysis
US10512911B1 (en) 2018-12-07 2019-12-24 Ultima Genomics, Inc. Implementing barriers for controlled environments during sample processing and detection

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE462454B (sv) 1988-11-10 1990-06-25 Pharmacia Ab Maetyta foer anvaendning i biosensorer
GB8910880D0 (en) * 1989-05-11 1989-06-28 Amersham Int Plc Sequencing method
CA2044616A1 (en) 1989-10-26 1991-04-27 Roger Y. Tsien Dna sequencing
US5583026A (en) * 1994-08-31 1996-12-10 Cornell Research Foundation, Inc. Process for reconstituting the polymerase III* and other subassemblies of E. coli DNA polymerase III holoenzyme from peptide subunits
GB9208733D0 (en) 1992-04-22 1992-06-10 Medical Res Council Dna sequencing method
US5360714A (en) * 1992-08-28 1994-11-01 Fox Chase Cancer Center Hepadnavirus polymerase gene product having RNA-dependent DNA priming and reverse transcriptase activities and methods of measuring the activities thereof
CA2158642A1 (en) 1993-03-19 1994-09-29 Hubert Koster Dna sequencing by mass spectrometry via exonuclease degradation
WO1995006138A1 (en) * 1993-08-25 1995-03-02 The Regents Of The University Of California Microscopic method for detecting micromotions
US5747247A (en) * 1994-07-25 1998-05-05 The Regents Of The University Of California Spectroscopic helicase assay
US5801042A (en) * 1994-08-18 1998-09-01 The Trustees Of Columbia University In The City Of New York Unique associated Kaposi's sarcoma virus sequences and uses thereof
US5753439A (en) * 1995-05-19 1998-05-19 Trustees Of Boston University Nucleic acid detection methods
CA2281205A1 (en) * 1997-02-12 1998-08-13 Eugene Y. Chan Methods and products for analyzing polymers
US6331392B1 (en) * 1997-03-05 2001-12-18 Anadys Pharmaceutical, Inc. Screen employing fluorescence anisotropy to identify compounds with affinity for nucleic acids
US6159687A (en) * 1997-03-18 2000-12-12 Novo Nordisk A/S Methods for generating recombined polynucleotides
KR100664331B1 (ko) 1997-07-28 2007-01-02 메디칼 바이오시스템스 리미티드 핵산 서열 분석
US7875440B2 (en) * 1998-05-01 2011-01-25 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US6263286B1 (en) * 1998-08-13 2001-07-17 U.S. Genomics, Inc. Methods of analyzing polymers using a spatial network of fluorophores and fluorescence resonance energy transfer
WO2000009757A1 (en) 1998-08-13 2000-02-24 U.S. Genomics, Inc. Optically characterizing polymers
US6210896B1 (en) * 1998-08-13 2001-04-03 Us Genomics Molecular motors
WO2000053805A1 (en) * 1999-03-10 2000-09-14 Asm Scientific, Inc. A method for direct nucleic acid sequencing
GB9907812D0 (en) * 1999-04-06 1999-06-02 Medical Biosystems Ltd Sequencing
US7056661B2 (en) * 1999-05-19 2006-06-06 Cornell Research Foundation, Inc. Method for sequencing nucleic acid molecules
US6335420B1 (en) 1999-11-22 2002-01-01 Ibc Advanced Technologies, Inc. Polyamide ligand-containing polymeric resins and methods of using the same for removing, separating and/or concentrating desired metal ions from solutions
GB9923644D0 (en) * 1999-10-06 1999-12-08 Medical Biosystems Ltd DNA sequencing
US6908736B1 (en) * 1999-10-06 2005-06-21 Medical Biosystems, Ltd. DNA sequencing method
GB0112238D0 (en) 2001-05-18 2001-07-11 Medical Biosystems Ltd Sequencing method
GB0317343D0 (en) * 2003-07-24 2003-08-27 Medical Biosystems Ltd Polynucleotide sequencing
GB0413082D0 (en) 2004-06-11 2004-07-14 Medical Biosystems Ltd Method
US8262900B2 (en) * 2006-12-14 2012-09-11 Life Technologies Corporation Methods and apparatus for measuring analytes using large scale FET arrays
US20100137143A1 (en) * 2008-10-22 2010-06-03 Ion Torrent Systems Incorporated Methods and apparatus for measuring analytes
US20100301398A1 (en) * 2009-05-29 2010-12-02 Ion Torrent Systems Incorporated Methods and apparatus for measuring analytes
US8574835B2 (en) * 2009-05-29 2013-11-05 Life Technologies Corporation Scaffolded nucleic acid polymer particles and methods of making and using
US8673627B2 (en) * 2009-05-29 2014-03-18 Life Technologies Corporation Apparatus and methods for performing electrochemical reactions

Also Published As

Publication number Publication date
PT1226271E (pt) 2008-05-23
KR100809171B1 (ko) 2008-02-29
CA2386115A1 (en) 2001-04-12
KR20020059444A (ko) 2002-07-12
JP5030249B2 (ja) 2012-09-19
DK1226271T3 (da) 2008-07-07
US20050214849A1 (en) 2005-09-29
EA200200428A1 (ru) 2002-10-31
WO2001025480A2 (en) 2001-04-12
CN1159457C (zh) 2004-07-28
AU7546700A (en) 2001-05-10
WO2001025480A3 (en) 2002-05-16
ATE388242T1 (de) 2008-03-15
JP2003511043A (ja) 2003-03-25
EP1226271A2 (de) 2002-07-31
US20120214164A1 (en) 2012-08-23
DE60038244T2 (de) 2009-04-23
GB9923644D0 (en) 1999-12-08
EA006702B1 (ru) 2006-02-24
JP2012196201A (ja) 2012-10-18
CN1391615A (zh) 2003-01-15
BR0014468A (pt) 2002-08-20
IL148678A (en) 2008-12-29
HK1045857A1 (en) 2002-12-13
NZ517775A (en) 2004-01-30
CA2386115C (en) 2010-06-15
IS6333A (is) 2002-04-05
DE60038244D1 (de) 2008-04-17
ES2302497T3 (es) 2008-07-16
MXPA02003534A (es) 2004-09-10
US7939264B1 (en) 2011-05-10
EP1226271B1 (de) 2008-03-05
AU769102B2 (en) 2004-01-15
US20110177520A1 (en) 2011-07-21

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