IL147854A0 - Multimeric compounds, contrast agents containing the same and diagnostic methods utilizing the same - Google Patents
Multimeric compounds, contrast agents containing the same and diagnostic methods utilizing the sameInfo
- Publication number
- IL147854A0 IL147854A0 IL14785400A IL14785400A IL147854A0 IL 147854 A0 IL147854 A0 IL 147854A0 IL 14785400 A IL14785400 A IL 14785400A IL 14785400 A IL14785400 A IL 14785400A IL 147854 A0 IL147854 A0 IL 147854A0
- Authority
- IL
- Israel
- Prior art keywords
- same
- contrast agents
- diagnostic methods
- agents containing
- methods utilizing
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 239000002872 contrast media Substances 0.000 title 1
- 238000002405 diagnostic procedure Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
- A61K49/0032—Methine dyes, e.g. cyanine dyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
- A61K49/0052—Small organic molecules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/12—Macromolecular compounds
- A61K49/124—Macromolecular compounds dendrimers, dendrons, hyperbranched compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/12—Macromolecular compounds
- A61K49/126—Linear polymers, e.g. dextran, inulin, PEG
- A61K49/128—Linear polymers, e.g. dextran, inulin, PEG comprising multiple complex or complex-forming groups, being either part of the linear polymeric backbone or being pending groups covalently linked to the linear polymeric backbone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/14—Peptides, e.g. proteins
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14641499P | 1999-07-29 | 1999-07-29 | |
US16365099P | 1999-11-04 | 1999-11-04 | |
PCT/US2000/020536 WO2001008712A2 (en) | 1999-07-29 | 2000-07-28 | Targeting multimeric imaging agents through multilocus binding |
Publications (1)
Publication Number | Publication Date |
---|---|
IL147854A0 true IL147854A0 (en) | 2002-08-14 |
Family
ID=26843871
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14785400A IL147854A0 (en) | 1999-07-29 | 2000-07-28 | Multimeric compounds, contrast agents containing the same and diagnostic methods utilizing the same |
Country Status (20)
Country | Link |
---|---|
US (2) | US6652835B1 (ja) |
EP (1) | EP1210124A2 (ja) |
JP (2) | JP2003505519A (ja) |
KR (1) | KR20020057946A (ja) |
CN (2) | CN1382062A (ja) |
AU (1) | AU6386000A (ja) |
BR (1) | BR0013171A (ja) |
CA (1) | CA2384565A1 (ja) |
CZ (1) | CZ2002343A3 (ja) |
EA (1) | EA200200220A1 (ja) |
HK (1) | HK1048952A1 (ja) |
HU (1) | HUP0202635A3 (ja) |
IL (1) | IL147854A0 (ja) |
IS (1) | IS6241A (ja) |
MX (1) | MXPA02001017A (ja) |
NO (1) | NO20020474L (ja) |
NZ (1) | NZ517017A (ja) |
PL (1) | PL353336A1 (ja) |
WO (1) | WO2001008712A2 (ja) |
YU (1) | YU6502A (ja) |
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EP1032430A2 (en) | 1997-11-17 | 2000-09-06 | Research Corporation Technologies, Inc. | Magnetic resonance imaging agents for the detection of physiological agents |
JP2003508027A (ja) * | 1999-07-29 | 2003-03-04 | ダイアックス コーポレイション | フィブリン結合性部分 |
AU6386000A (en) * | 1999-07-29 | 2001-02-19 | Epix Pharmaceuticals, Inc. | Targeting multimeric imaging agents through multilocus binding |
US6673333B1 (en) | 2000-05-04 | 2004-01-06 | Research Corporation Technologies, Inc. | Functional MRI agents for cancer imaging |
WO2002006287A2 (en) | 2000-07-17 | 2002-01-24 | California Institute Of Technology | Macrocyclic mri contrast agents |
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US7469076B2 (en) * | 2003-09-03 | 2008-12-23 | Receptors Llc | Sensors employing combinatorial artificial receptors |
US20050136483A1 (en) * | 2003-09-03 | 2005-06-23 | Receptors Llc | Nanodevices employing combinatorial artificial receptors |
US20050037429A1 (en) * | 2003-03-28 | 2005-02-17 | Receptors Llc | Artificial receptors including reversibly immobilized building blocks and methods |
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EP1613737A4 (en) * | 2003-03-28 | 2008-12-03 | Receptors Llc | ARTIFICIAL RECEPTORS COMPRISING REVERSIBLE IMMOBILIZED CONSTRUCTION BLOCKS AND METHODS |
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AR047692A1 (es) * | 2003-07-10 | 2006-02-08 | Epix Medical Inc | Imagenes de blancos estacionarios |
CN100528076C (zh) * | 2003-12-08 | 2009-08-19 | 西门子公司 | 通过顺磁性水溶材料来降低冷却剂的弛豫时间的应用 |
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EP1789797A1 (en) * | 2004-09-03 | 2007-05-30 | Receptors LLC | Combinatorial artifical receptors including tether building blocks |
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US7985715B2 (en) | 2004-09-11 | 2011-07-26 | Receptors Llc | Combinatorial artificial receptors including peptide building blocks |
WO2006056227A1 (en) * | 2004-11-27 | 2006-06-01 | Eberhard-Karls- Universität Tübingen Universitätsklinikum | Conjugates comprising the active agent and flanking or branched-chain peptides |
DE102004062258B3 (de) * | 2004-12-23 | 2006-01-05 | Schering Ag | Hydroxypyridinon-Derivate, deren Metallkomplexe und deren Verwendung zur Herstellung von Konjugaten mit Biomolekülen |
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US20060275217A1 (en) * | 2005-05-06 | 2006-12-07 | Caravan Peter D | Chemical exchange saturation transfer contrast agents |
EP1901659B1 (en) * | 2005-07-13 | 2018-04-25 | Georgia State University Research Foundation, Inc. | Contrast agents and methods for preparing contrast agents |
AU2006303324A1 (en) * | 2005-10-18 | 2007-04-26 | Cinvention Ag | Thermoset particles and methods for production thereof |
US20070264678A1 (en) | 2005-10-28 | 2007-11-15 | Invitrogen Corporation | Kinase and ubiquination assays |
US20070293656A1 (en) | 2005-12-29 | 2007-12-20 | Epix Pharmaceuticals, Inc. | Collagen binding peptides |
KR101336505B1 (ko) * | 2006-08-17 | 2013-12-05 | 에픽스 파마슈티칼스, 인코포레이티드 | 림프계의 영상화 방법 |
EP2156186A4 (en) * | 2007-05-03 | 2010-11-03 | Tethys Bioscience Inc | BINDING REAGENTS WITH SMALL EPITOP BINDING MOLECULES |
DE102007028090A1 (de) | 2007-06-12 | 2008-12-18 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | Aktivierbare diagnostische und therapeutische Verbindung |
WO2009023813A1 (en) * | 2007-08-15 | 2009-02-19 | Applied Soil Water Technologies Llc | Metals recovery from mining heap leach ore |
US20090214436A1 (en) * | 2008-02-18 | 2009-08-27 | Washington University | Dichromic fluorescent compounds |
US8722020B2 (en) | 2010-03-31 | 2014-05-13 | General Electric Company | Hydroxylated contrast enhancement agents |
US8765977B2 (en) | 2010-03-31 | 2014-07-01 | General Electric Company | Hydroxylated contrast enhancement agents and imaging method |
US8362281B2 (en) | 2010-03-31 | 2013-01-29 | General Electric Company | Intermediates for hydroxylated contrast enhancement agents |
EP3553075A1 (en) | 2012-01-23 | 2019-10-16 | Washington University | Goggle imaging systems and methods |
US9849201B2 (en) | 2013-05-03 | 2017-12-26 | Washington University | Homing agents |
US10806804B2 (en) | 2015-05-06 | 2020-10-20 | Washington University | Compounds having RD targeting motifs and methods of use thereof |
US10301358B2 (en) | 2015-06-29 | 2019-05-28 | Collagen Medical, LLC | Collagen imaging compositions |
CA2995210A1 (en) | 2015-08-13 | 2017-02-16 | The General Hospital Corporation | Manganese-based chelate conjugates for molecular mr imaging |
WO2018144849A1 (en) * | 2017-02-02 | 2018-08-09 | The University Of Akron | Functionalized poly(propylene fumarate) polymers made by ring opening polymerization using magnesium catalysts |
EP4072598A4 (en) | 2019-12-13 | 2024-02-21 | Washington University | NEAR-INFRARED FLUORESCENT DYES, FORMULATIONS AND ASSOCIATED METHODS |
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-
2000
- 2000-07-28 AU AU63860/00A patent/AU6386000A/en not_active Abandoned
- 2000-07-28 US US09/627,719 patent/US6652835B1/en not_active Expired - Fee Related
- 2000-07-28 WO PCT/US2000/020536 patent/WO2001008712A2/en not_active Application Discontinuation
- 2000-07-28 CN CN00813045A patent/CN1382062A/zh active Pending
- 2000-07-28 BR BR0013171-7A patent/BR0013171A/pt not_active IP Right Cessation
- 2000-07-28 CA CA002384565A patent/CA2384565A1/en not_active Abandoned
- 2000-07-28 MX MXPA02001017A patent/MXPA02001017A/es unknown
- 2000-07-28 NZ NZ517017A patent/NZ517017A/en unknown
- 2000-07-28 CN CNA2004100567047A patent/CN1626246A/zh active Pending
- 2000-07-28 KR KR1020027001126A patent/KR20020057946A/ko not_active Application Discontinuation
- 2000-07-28 IL IL14785400A patent/IL147854A0/xx unknown
- 2000-07-28 EP EP00950815A patent/EP1210124A2/en not_active Withdrawn
- 2000-07-28 JP JP2001513442A patent/JP2003505519A/ja active Pending
- 2000-07-28 CZ CZ2002343A patent/CZ2002343A3/cs unknown
- 2000-07-28 YU YU6502A patent/YU6502A/sh unknown
- 2000-07-28 PL PL00353336A patent/PL353336A1/xx not_active Application Discontinuation
- 2000-07-28 HU HU0202635A patent/HUP0202635A3/hu unknown
- 2000-07-28 EA EA200200220A patent/EA200200220A1/ru unknown
-
2002
- 2002-01-18 IS IS6241A patent/IS6241A/is unknown
- 2002-01-29 NO NO20020474A patent/NO20020474L/no not_active Application Discontinuation
- 2002-11-25 JP JP2002341392A patent/JP2003201258A/ja active Pending
-
2003
- 2003-02-19 HK HK03101252.8A patent/HK1048952A1/zh unknown
- 2003-05-27 US US10/445,544 patent/US20040005274A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CN1626246A (zh) | 2005-06-15 |
BR0013171A (pt) | 2002-05-28 |
JP2003505519A (ja) | 2003-02-12 |
YU6502A (sh) | 2005-06-10 |
PL353336A1 (en) | 2003-11-17 |
NO20020474L (no) | 2002-03-27 |
IS6241A (is) | 2002-01-18 |
HK1048952A1 (zh) | 2003-04-25 |
EP1210124A2 (en) | 2002-06-05 |
HUP0202635A3 (en) | 2006-03-28 |
JP2003201258A (ja) | 2003-07-18 |
AU6386000A (en) | 2001-02-19 |
CN1382062A (zh) | 2002-11-27 |
NO20020474D0 (no) | 2002-01-29 |
US6652835B1 (en) | 2003-11-25 |
WO2001008712A2 (en) | 2001-02-08 |
KR20020057946A (ko) | 2002-07-12 |
CA2384565A1 (en) | 2001-02-08 |
CZ2002343A3 (cs) | 2002-08-14 |
HUP0202635A2 (hu) | 2002-11-28 |
US20040005274A1 (en) | 2004-01-08 |
MXPA02001017A (es) | 2002-08-12 |
NZ517017A (en) | 2004-05-28 |
WO2001008712A3 (en) | 2002-03-14 |
EA200200220A1 (ru) | 2002-08-29 |
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