IL147668A0 - A process for the preparation of venlafaxin - Google Patents
A process for the preparation of venlafaxinInfo
- Publication number
- IL147668A0 IL147668A0 IL14766800A IL14766800A IL147668A0 IL 147668 A0 IL147668 A0 IL 147668A0 IL 14766800 A IL14766800 A IL 14766800A IL 14766800 A IL14766800 A IL 14766800A IL 147668 A0 IL147668 A0 IL 147668A0
- Authority
- IL
- Israel
- Prior art keywords
- venlafaxin
- preparation
- general formula
- physiologically acceptable
- compound
- Prior art date
Links
- PNVNVHUZROJLTJ-UHFFFAOYSA-N venlafaxine Chemical compound C1=CC(OC)=CC=C1C(CN(C)C)C1(O)CCCCC1 PNVNVHUZROJLTJ-UHFFFAOYSA-N 0.000 title abstract 3
- 229960004688 venlafaxine Drugs 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002901 organomagnesium compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES009901686A ES2152902B1 (es) | 1999-07-27 | 1999-07-27 | Procedimiento de obtencion de venlafaxina |
| PCT/ES2000/000255 WO2001007397A1 (es) | 1999-07-27 | 2000-07-17 | Procedimiento de obtencion de venlafaxina |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL147668A0 true IL147668A0 (en) | 2002-08-14 |
Family
ID=8309382
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL14766800A IL147668A0 (en) | 1999-07-27 | 2000-07-17 | A process for the preparation of venlafaxin |
| IL147668A IL147668A (en) | 1999-07-27 | 2002-01-16 | Process for the preparation of venlafaxin |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL147668A IL147668A (en) | 1999-07-27 | 2002-01-16 | Process for the preparation of venlafaxin |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6506941B1 (de) |
| EP (1) | EP1213279B1 (de) |
| AT (1) | ATE276229T1 (de) |
| AU (1) | AU5987400A (de) |
| CA (1) | CA2380854A1 (de) |
| DE (1) | DE60013861T2 (de) |
| DK (1) | DK1213279T3 (de) |
| ES (2) | ES2152902B1 (de) |
| IL (2) | IL147668A0 (de) |
| PT (1) | PT1213279E (de) |
| SI (1) | SI1213279T1 (de) |
| WO (1) | WO2001007397A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040186310A1 (en) * | 2001-06-22 | 2004-09-23 | Kim Keun-Sik | Process for preparation of cyclohexanol derivatives |
| AR039164A1 (es) | 2002-03-28 | 2005-02-09 | Synthon Bv | Sales de venlafaxina de baja solubilidad en agua |
| WO2003082804A1 (en) | 2002-03-28 | 2003-10-09 | Synthon B.V. | Venlafaxine besylate |
| KR20080056311A (ko) * | 2005-10-19 | 2008-06-20 | 테바 파마슈티컬 인더스트리즈 리미티드 | 고순도1-[2-디메틸아미노-(4-메톡시페닐)에틸)시클로헥산올염산염의 제조 방법 |
| US8063050B2 (en) | 2006-07-06 | 2011-11-22 | Array Biopharma Inc. | Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors |
| UA95641C2 (xx) * | 2006-07-06 | 2011-08-25 | Эррей Биофарма Инк. | Гідроксильовані піримідильні циклопентани як інгібітори акт протеїнкінази$гидроксилированные пиримидильные циклопентаны как ингибиторы акт протеинкиназы |
| US20080081067A1 (en) * | 2006-10-03 | 2008-04-03 | Gupta Manishkumar | Sustained release pharmaceutical compositions of venlafaxine and process for preparation thereof |
| WO2011007136A2 (en) * | 2009-07-16 | 2011-01-20 | Cipla Limited | Process for the preparation of o-desmethyl venlafaxine and intermediate for use therein |
| CN115650863B (zh) * | 2022-09-05 | 2024-06-25 | 上海博纳赛恩医药研发有限公司 | 制备文拉法辛盐酸盐的方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES8802131A1 (es) * | 1982-12-13 | 1988-04-01 | American Home Prod | Un procedimiento para la produccion de derivados de feniletilamina. |
| GB8902209D0 (en) * | 1989-02-01 | 1989-03-22 | Wyeth John And Brother Limited | Preparation of cyclohexanol derivatives and novel thioamide intermediates |
-
1999
- 1999-07-27 ES ES009901686A patent/ES2152902B1/es not_active Expired - Fee Related
-
2000
- 2000-07-17 AU AU59874/00A patent/AU5987400A/en not_active Abandoned
- 2000-07-17 PT PT00945958T patent/PT1213279E/pt unknown
- 2000-07-17 AT AT00945958T patent/ATE276229T1/de not_active IP Right Cessation
- 2000-07-17 IL IL14766800A patent/IL147668A0/xx active IP Right Grant
- 2000-07-17 DE DE60013861T patent/DE60013861T2/de not_active Expired - Fee Related
- 2000-07-17 EP EP00945958A patent/EP1213279B1/de not_active Expired - Lifetime
- 2000-07-17 WO PCT/ES2000/000255 patent/WO2001007397A1/es not_active Ceased
- 2000-07-17 US US10/048,107 patent/US6506941B1/en not_active Expired - Fee Related
- 2000-07-17 ES ES00945958T patent/ES2226877T3/es not_active Expired - Lifetime
- 2000-07-17 SI SI200030552T patent/SI1213279T1/xx unknown
- 2000-07-17 CA CA002380854A patent/CA2380854A1/en not_active Abandoned
- 2000-07-17 DK DK00945958T patent/DK1213279T3/da active
-
2002
- 2002-01-16 IL IL147668A patent/IL147668A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PT1213279E (pt) | 2005-01-31 |
| EP1213279B1 (de) | 2004-09-15 |
| ES2226877T3 (es) | 2005-04-01 |
| AU5987400A (en) | 2001-02-13 |
| DE60013861T2 (de) | 2005-09-29 |
| DK1213279T3 (da) | 2005-01-10 |
| WO2001007397A1 (es) | 2001-02-01 |
| ES2152902A1 (es) | 2001-02-01 |
| IL147668A (en) | 2006-08-20 |
| EP1213279A1 (de) | 2002-06-12 |
| DE60013861D1 (de) | 2004-10-21 |
| SI1213279T1 (en) | 2005-04-30 |
| CA2380854A1 (en) | 2001-02-01 |
| ES2152902B1 (es) | 2001-08-16 |
| ATE276229T1 (de) | 2004-10-15 |
| US6506941B1 (en) | 2003-01-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed |