DE60013861D1 - Herstellungsverfahren für venlafaxin - Google Patents

Herstellungsverfahren für venlafaxin

Info

Publication number
DE60013861D1
DE60013861D1 DE60013861T DE60013861T DE60013861D1 DE 60013861 D1 DE60013861 D1 DE 60013861D1 DE 60013861 T DE60013861 T DE 60013861T DE 60013861 T DE60013861 T DE 60013861T DE 60013861 D1 DE60013861 D1 DE 60013861D1
Authority
DE
Germany
Prior art keywords
venlafaxin
manufacturing process
general formula
physiologically acceptable
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60013861T
Other languages
English (en)
Other versions
DE60013861T2 (de
Inventor
I Aguilar Carmen Arnalot
I Llado Jordi Bosch
Garcia Pelayo Camps
Miguel Maria Del Carme Onrubia
Madrid Nuria Soldevilla
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medichem SA
Original Assignee
Medichem SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medichem SA filed Critical Medichem SA
Publication of DE60013861D1 publication Critical patent/DE60013861D1/de
Application granted granted Critical
Publication of DE60013861T2 publication Critical patent/DE60013861T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
DE60013861T 1999-07-27 2000-07-17 Herstellungsverfahren für venlafaxin Expired - Fee Related DE60013861T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES9901686 1999-07-27
ES009901686A ES2152902B1 (es) 1999-07-27 1999-07-27 Procedimiento de obtencion de venlafaxina
PCT/ES2000/000255 WO2001007397A1 (es) 1999-07-27 2000-07-17 Procedimiento de obtencion de venlafaxina

Publications (2)

Publication Number Publication Date
DE60013861D1 true DE60013861D1 (de) 2004-10-21
DE60013861T2 DE60013861T2 (de) 2005-09-29

Family

ID=8309382

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60013861T Expired - Fee Related DE60013861T2 (de) 1999-07-27 2000-07-17 Herstellungsverfahren für venlafaxin

Country Status (12)

Country Link
US (1) US6506941B1 (de)
EP (1) EP1213279B1 (de)
AT (1) ATE276229T1 (de)
AU (1) AU5987400A (de)
CA (1) CA2380854A1 (de)
DE (1) DE60013861T2 (de)
DK (1) DK1213279T3 (de)
ES (2) ES2152902B1 (de)
IL (2) IL147668A0 (de)
PT (1) PT1213279E (de)
SI (1) SI1213279T1 (de)
WO (1) WO2001007397A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040186310A1 (en) * 2001-06-22 2004-09-23 Kim Keun-Sik Process for preparation of cyclohexanol derivatives
AR039164A1 (es) 2002-03-28 2005-02-09 Synthon Bv Sales de venlafaxina de baja solubilidad en agua
WO2003082804A1 (en) 2002-03-28 2003-10-09 Synthon B.V. Venlafaxine besylate
CA2625832A1 (en) * 2005-10-19 2007-04-26 Vinod Kumar Kansal Process for the preparation of highly pure 1-[2-dimethylamino-(4-methoxyphenyl) ethyl]cyclohexanol hydrochloride
US8063050B2 (en) 2006-07-06 2011-11-22 Array Biopharma Inc. Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors
UA95641C2 (en) * 2006-07-06 2011-08-25 Эррей Биофарма Инк. Hydroxylated cyclopenta [d] pyrimidines as akt protein kinase inhibitors
US20080081067A1 (en) * 2006-10-03 2008-04-03 Gupta Manishkumar Sustained release pharmaceutical compositions of venlafaxine and process for preparation thereof
KR20120064668A (ko) * 2009-07-16 2012-06-19 시플라 리미티드 Ｏ-데스메틸 벤라팍신의 제조방법 및 이에 사용되는 중간체

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8802131A1 (es) * 1982-12-13 1988-04-01 American Home Prod Un procedimiento para la produccion de derivados de feniletilamina.
GB8902209D0 (en) * 1989-02-01 1989-03-22 Wyeth John And Brother Limited Preparation of cyclohexanol derivatives and novel thioamide intermediates

Also Published As

Publication number Publication date
PT1213279E (pt) 2005-01-31
WO2001007397A1 (es) 2001-02-01
SI1213279T1 (en) 2005-04-30
ES2152902B1 (es) 2001-08-16
ES2226877T3 (es) 2005-04-01
EP1213279B1 (de) 2004-09-15
IL147668A (en) 2006-08-20
IL147668A0 (en) 2002-08-14
EP1213279A1 (de) 2002-06-12
AU5987400A (en) 2001-02-13
US6506941B1 (en) 2003-01-14
DK1213279T3 (da) 2005-01-10
CA2380854A1 (en) 2001-02-01
ES2152902A1 (es) 2001-02-01
DE60013861T2 (de) 2005-09-29
ATE276229T1 (de) 2004-10-15

Similar Documents

Publication Publication Date Title
SE8200815L (sv) Kemisk forening till anvendning som mellanprodukt vid framstellning av vissa triazolforeningar
ES2195510T3 (es) Derivados de imidazopiridina y procedimiento para prepararlos.
DE60013861D1 (de) Herstellungsverfahren für venlafaxin
ATE71952T1 (de) Verfahren zur herstellung von 4-aminoandrostendion-derivaten.
DK0485204T3 (da) Fremgangsmåde til fremstilling af 3-alkoxymethyl-cephalosporin-derivater
ES2089097T3 (es) Procedimiento para la fabricacion de derivados de bencilftalacinona y sales de la misma.
DE69800073D1 (de) Verfahren zur Herstellung von 2-Cyanobiphenyl-Verbindungen
DE69733716D1 (de) Verfahren zur herstellung von imidazolderivaten
DE69928610D1 (de) Verfahren zur Herstellung von 2-Carbamoyl-Pyridinen
DE69129605T2 (de) Verfahren zur Herstellung von N-Alkylpyrazolen
DE60000375D1 (de) Verfahren zur Herstellung von Difluoracetophenon-Derivaten
DE69818837D1 (de) Verfahren zur herstellung von 5-hydroxymethylthiazole
ATE250044T1 (de) Herstellung von derivaten von 2-aminothiazol hydrobromid z-isomeren
DE68926016D1 (de) Halogeno-4-Methylpyrazole und Verfahren zu ihrer Herstellung
EP1219610A4 (de) Verfahren zur herstellung von oxazol-derivaten
ATE396975T1 (de) 5-aminopyrazol-4-carboxylat derivate und verfahren zu ihrer herstellung
AU556819B2 (en) 2-triazolyl-1-phenylethane derivatives
FI961749A0 (fi) Menetelmä metaanidifosfonihappoyhdisteen valmistamiseksi
ES2055018T3 (es) Preparacion de dienos conjugados.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee