DK1213279T3 - Fremgangsmåde til fremstilling af venlafaxin - Google Patents

Fremgangsmåde til fremstilling af venlafaxin

Info

Publication number
DK1213279T3
DK1213279T3 DK00945958T DK00945958T DK1213279T3 DK 1213279 T3 DK1213279 T3 DK 1213279T3 DK 00945958 T DK00945958 T DK 00945958T DK 00945958 T DK00945958 T DK 00945958T DK 1213279 T3 DK1213279 T3 DK 1213279T3
Authority
DK
Denmark
Prior art keywords
preparation
venlafaxin
general formula
physiologically acceptable
venlafaxine
Prior art date
Application number
DK00945958T
Other languages
English (en)
Inventor
I Llado Jordi Bosch
Garcia Pelayo Camps
Miguel Maria Del Carme Onrubia
Madrid Nuria Soldevilla
I Aguilar Carmen Arnalot
Original Assignee
Medichem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medichem Sa filed Critical Medichem Sa
Application granted granted Critical
Publication of DK1213279T3 publication Critical patent/DK1213279T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/74Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
DK00945958T 1999-07-27 2000-07-17 Fremgangsmåde til fremstilling af venlafaxin DK1213279T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES009901686A ES2152902B1 (es) 1999-07-27 1999-07-27 Procedimiento de obtencion de venlafaxina
EP00945958A EP1213279B1 (en) 1999-07-27 2000-07-17 Venlafaxine production process
PCT/ES2000/000255 WO2001007397A1 (es) 1999-07-27 2000-07-17 Procedimiento de obtencion de venlafaxina

Publications (1)

Publication Number Publication Date
DK1213279T3 true DK1213279T3 (da) 2005-01-10

Family

ID=8309382

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00945958T DK1213279T3 (da) 1999-07-27 2000-07-17 Fremgangsmåde til fremstilling af venlafaxin

Country Status (12)

Country Link
US (1) US6506941B1 (da)
EP (1) EP1213279B1 (da)
AT (1) ATE276229T1 (da)
AU (1) AU5987400A (da)
CA (1) CA2380854A1 (da)
DE (1) DE60013861T2 (da)
DK (1) DK1213279T3 (da)
ES (2) ES2152902B1 (da)
IL (2) IL147668A0 (da)
PT (1) PT1213279E (da)
SI (1) SI1213279T1 (da)
WO (1) WO2001007397A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040186310A1 (en) * 2001-06-22 2004-09-23 Kim Keun-Sik Process for preparation of cyclohexanol derivatives
US6696496B2 (en) 2002-03-28 2004-02-24 Synthon Bv Low water-soluble venlafaxine salts
EP1485344A1 (en) 2002-03-28 2004-12-15 Synthon B.V. Venlafaxine besylate
JP2009511641A (ja) * 2005-10-19 2009-03-19 テバ ファーマシューティカル インダストリーズ リミティド 高純度1−〔2−ジメチルアミノ−(4−メトキシフェニル)エチル〕シクロヘキサノール塩酸塩の調製方法
US8063050B2 (en) 2006-07-06 2011-11-22 Array Biopharma Inc. Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors
UA95641C2 (en) * 2006-07-06 2011-08-25 Эррей Биофарма Инк. Hydroxylated cyclopenta [d] pyrimidines as akt protein kinase inhibitors
US20080081067A1 (en) * 2006-10-03 2008-04-03 Gupta Manishkumar Sustained release pharmaceutical compositions of venlafaxine and process for preparation thereof
US9012689B2 (en) 2009-07-16 2015-04-21 Cipla Limited Process for the preparation of O-desmethyl venlafaxine and intermediate for use therein
CN115650863B (zh) * 2022-09-05 2024-06-25 上海博纳赛恩医药研发有限公司 制备文拉法辛盐酸盐的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8802131A1 (es) * 1982-12-13 1988-04-01 American Home Prod Un procedimiento para la produccion de derivados de feniletilamina.
GB8902209D0 (en) * 1989-02-01 1989-03-22 Wyeth John And Brother Limited Preparation of cyclohexanol derivatives and novel thioamide intermediates

Also Published As

Publication number Publication date
IL147668A0 (en) 2002-08-14
WO2001007397A1 (es) 2001-02-01
EP1213279B1 (en) 2004-09-15
PT1213279E (pt) 2005-01-31
IL147668A (en) 2006-08-20
DE60013861D1 (de) 2004-10-21
ES2152902B1 (es) 2001-08-16
CA2380854A1 (en) 2001-02-01
AU5987400A (en) 2001-02-13
ES2226877T3 (es) 2005-04-01
ATE276229T1 (de) 2004-10-15
US6506941B1 (en) 2003-01-14
ES2152902A1 (es) 2001-02-01
SI1213279T1 (en) 2005-04-30
EP1213279A1 (en) 2002-06-12
DE60013861T2 (de) 2005-09-29

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