ATE276229T1 - Herstellungsverfahren für venlafaxin - Google Patents

Herstellungsverfahren für venlafaxin

Info

Publication number
ATE276229T1
ATE276229T1 AT00945958T AT00945958T ATE276229T1 AT E276229 T1 ATE276229 T1 AT E276229T1 AT 00945958 T AT00945958 T AT 00945958T AT 00945958 T AT00945958 T AT 00945958T AT E276229 T1 ATE276229 T1 AT E276229T1
Authority
AT
Austria
Prior art keywords
venlafaxine
production method
venlafaxin
general formula
physiologically acceptable
Prior art date
Application number
AT00945958T
Other languages
English (en)
Inventor
I Aguilar Carmen Arnalot
I Llado Jordi Bosch
Garcia Pelayo Camps
Miguel Maria Del Carme Onrubia
Madrid Nuria Soldevilla
Original Assignee
Medichem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medichem Sa filed Critical Medichem Sa
Application granted granted Critical
Publication of ATE276229T1 publication Critical patent/ATE276229T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
AT00945958T 1999-07-27 2000-07-17 Herstellungsverfahren für venlafaxin ATE276229T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES009901686A ES2152902B1 (es) 1999-07-27 1999-07-27 Procedimiento de obtencion de venlafaxina
PCT/ES2000/000255 WO2001007397A1 (es) 1999-07-27 2000-07-17 Procedimiento de obtencion de venlafaxina

Publications (1)

Publication Number Publication Date
ATE276229T1 true ATE276229T1 (de) 2004-10-15

Family

ID=8309382

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00945958T ATE276229T1 (de) 1999-07-27 2000-07-17 Herstellungsverfahren für venlafaxin

Country Status (12)

Country Link
US (1) US6506941B1 (de)
EP (1) EP1213279B1 (de)
AT (1) ATE276229T1 (de)
AU (1) AU5987400A (de)
CA (1) CA2380854A1 (de)
DE (1) DE60013861T2 (de)
DK (1) DK1213279T3 (de)
ES (2) ES2152902B1 (de)
IL (2) IL147668A0 (de)
PT (1) PT1213279E (de)
SI (1) SI1213279T1 (de)
WO (1) WO2001007397A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040186310A1 (en) * 2001-06-22 2004-09-23 Kim Keun-Sik Process for preparation of cyclohexanol derivatives
WO2003082804A1 (en) 2002-03-28 2003-10-09 Synthon B.V. Venlafaxine besylate
AU2003226751A1 (en) 2002-03-28 2003-10-13 Synthon B.V. Low water-soluble venlafaxine salts
KR20080056311A (ko) * 2005-10-19 2008-06-20 테바 파마슈티컬 인더스트리즈 리미티드 고순도1-[2-디메틸아미노-(4-메톡시페닐)에틸)시클로헥산올염산염의 제조 방법
US8063050B2 (en) 2006-07-06 2011-11-22 Array Biopharma Inc. Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors
UA95641C2 (xx) * 2006-07-06 2011-08-25 Эррей Биофарма Инк. Гідроксильовані піримідильні циклопентани як інгібітори акт протеїнкінази$гидроксилированные пиримидильные циклопентаны как ингибиторы акт протеинкиназы
US20080081067A1 (en) * 2006-10-03 2008-04-03 Gupta Manishkumar Sustained release pharmaceutical compositions of venlafaxine and process for preparation thereof
JP2012532923A (ja) * 2009-07-16 2012-12-20 シプラ・リミテッド Ｏ−デスメチルベンラファキシンの製造方法及びそれに使用される中間体
CN115650863B (zh) * 2022-09-05 2024-06-25 上海博纳赛恩医药研发有限公司 制备文拉法辛盐酸盐的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8802131A1 (es) * 1982-12-13 1988-04-01 American Home Prod Un procedimiento para la produccion de derivados de feniletilamina.
GB8902209D0 (en) * 1989-02-01 1989-03-22 Wyeth John And Brother Limited Preparation of cyclohexanol derivatives and novel thioamide intermediates

Also Published As

Publication number Publication date
WO2001007397A1 (es) 2001-02-01
ES2152902A1 (es) 2001-02-01
PT1213279E (pt) 2005-01-31
ES2152902B1 (es) 2001-08-16
EP1213279A1 (de) 2002-06-12
AU5987400A (en) 2001-02-13
SI1213279T1 (en) 2005-04-30
ES2226877T3 (es) 2005-04-01
IL147668A0 (en) 2002-08-14
CA2380854A1 (en) 2001-02-01
DK1213279T3 (da) 2005-01-10
EP1213279B1 (de) 2004-09-15
IL147668A (en) 2006-08-20
US6506941B1 (en) 2003-01-14
DE60013861D1 (de) 2004-10-21
DE60013861T2 (de) 2005-09-29

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