IL145670A0 - Prodrugs of thrombin inhibitors - Google Patents

Prodrugs of thrombin inhibitors

Info

Publication number
IL145670A0
IL145670A0 IL14567000A IL14567000A IL145670A0 IL 145670 A0 IL145670 A0 IL 145670A0 IL 14567000 A IL14567000 A IL 14567000A IL 14567000 A IL14567000 A IL 14567000A IL 145670 A0 IL145670 A0 IL 145670A0
Authority
IL
Israel
Prior art keywords
prodrugs
thrombin inhibitors
thrombin
inhibitors
Prior art date
Application number
IL14567000A
Other languages
English (en)
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26004346&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL145670(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Basf Ag filed Critical Basf Ag
Publication of IL145670A0 publication Critical patent/IL145670A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B43/00—Formation or introduction of functional groups containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
IL14567000A 1999-04-09 2000-04-05 Prodrugs of thrombin inhibitors IL145670A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19915930 1999-04-09
DE10006799 2000-02-15
PCT/EP2000/003008 WO2000061577A1 (de) 1999-04-09 2000-04-05 Prodrugs von thrombininhibitoren

Publications (1)

Publication Number Publication Date
IL145670A0 true IL145670A0 (en) 2002-06-30

Family

ID=26004346

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14567000A IL145670A0 (en) 1999-04-09 2000-04-05 Prodrugs of thrombin inhibitors

Country Status (16)

Country Link
EP (1) EP1169318A1 (ja)
JP (1) JP2002541254A (ja)
KR (1) KR20020004995A (ja)
CN (1) CN1349526A (ja)
AU (1) AU3659200A (ja)
BG (1) BG105985A (ja)
BR (1) BR0009653A (ja)
CA (1) CA2368830A1 (ja)
HK (1) HK1045516A1 (ja)
HU (1) HUP0202431A3 (ja)
IL (1) IL145670A0 (ja)
NO (1) NO20014807L (ja)
PL (1) PL352834A1 (ja)
SK (1) SK14092001A3 (ja)
TR (1) TR200102914T2 (ja)
WO (1) WO2000061577A1 (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10064797A1 (de) * 2000-12-22 2002-06-27 Knoll Ag Orale und parenterale pharmazeutische Formulierung, umfassend eine niedermolekulare Thrombininhibitor-Pro-Pharmakon
MXPA04012396A (es) * 2002-06-14 2005-06-17 Sato Fumihiko Compuestos de imidazol, metodos y uso para la produccion de los mismos.
JP5140428B2 (ja) 2004-08-23 2013-02-06 ロッコ・システムズ・プライベイト・リミテッド 集積回路ダイシング装置のチャック用供給機構

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4421052A1 (de) * 1994-06-17 1995-12-21 Basf Ag Neue Thrombininhibitoren, ihre Herstellung und Verwendung
NZ302649A (en) * 1995-02-17 2000-01-28 Basf Ag Dipeptide amidine derivatives, preparation and pharmaceutical compositions thereof
DE19631084A1 (de) * 1996-08-01 1998-02-05 Basf Ag Verwendung von (Meth)acrylsäure-Copolymeren zur Erhöhung der Permeabilität der Schleimhaut
DE19635674A1 (de) * 1996-09-03 1998-03-05 Basf Ag Verfahren zur Herstellung von Amidinen

Also Published As

Publication number Publication date
WO2000061577A1 (de) 2000-10-19
PL352834A1 (en) 2003-09-08
TR200102914T2 (tr) 2002-01-21
CN1349526A (zh) 2002-05-15
HUP0202431A2 (hu) 2002-11-28
CA2368830A1 (en) 2000-10-19
HUP0202431A3 (en) 2003-03-28
SK14092001A3 (sk) 2002-05-09
BR0009653A (pt) 2002-01-08
JP2002541254A (ja) 2002-12-03
AU3659200A (en) 2000-11-14
NO20014807D0 (no) 2001-10-03
HK1045516A1 (zh) 2002-11-29
EP1169318A1 (de) 2002-01-09
BG105985A (en) 2002-06-28
NO20014807L (no) 2001-12-04
KR20020004995A (ko) 2002-01-16

Similar Documents

Publication Publication Date Title
IL146518A0 (en) Metalloprotease inhibitors
IL149118A0 (en) Inhibitors of neuraminidases
EP1124822A4 (en) THROMBIN INHIBITORS
GB9900416D0 (en) Inhibitors
IL145772A0 (en) Prodrugs of thrombin inhibitors
PL350452A1 (en) Dihetero-substituted metalloprotease inhibitors
GB9930659D0 (en) Inhibitors of complement activation
EP1117660A4 (en) THROMBIN INHIBITORS
IL136139A0 (en) Thrombin inhibitors
EP1153022A4 (en) PROTEASE INHIBITORS
GB0030284D0 (en) Enzyme inhibitors
EP1232155A4 (en) PROTEASE INHIBITORS
EP1229912A4 (en) PROTEASE INHIBITORS
EP1229915A4 (en) PROTEASE INHIBITORS
EP1229914A4 (en) PROTEASE INHIBITORS
EP1231921A4 (en) PROTEASE INHIBITORS
EP1229911A4 (en) PROTEASE INHIBITORS
EP1173429A4 (en) PROTEASE INHIBITORS
EP1161237A4 (en) PROTEASE INHIBITORS
EP1233771A4 (en) PROTEASE INHIBITORS
EP1231923A4 (en) PROTEASE INHIBITORS
IL145670A0 (en) Prodrugs of thrombin inhibitors
EP1189618A4 (en) thrombin
PL347152A1 (en) Benzamide derivatives as thrombin inhibitors
EP1231922A4 (en) PROTEASE INHIBITORS

Legal Events

Date Code Title Description
HP Change in proprietorship