IL145607A0 - Diagnostic sequencing by a combination of specific cleavage and mass spectrometry - Google Patents

Diagnostic sequencing by a combination of specific cleavage and mass spectrometry

Info

Publication number
IL145607A0
IL145607A0 IL14560700A IL14560700A IL145607A0 IL 145607 A0 IL145607 A0 IL 145607A0 IL 14560700 A IL14560700 A IL 14560700A IL 14560700 A IL14560700 A IL 14560700A IL 145607 A0 IL145607 A0 IL 145607A0
Authority
IL
Israel
Prior art keywords
sequencing
diagnostic
areas
combination
nucleic acid
Prior art date
Application number
IL14560700A
Other languages
English (en)
Original Assignee
Methexis N V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Methexis N V filed Critical Methexis N V
Publication of IL145607A0 publication Critical patent/IL145607A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6872—Methods for sequencing involving mass spectrometry
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Theoretical Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
IL14560700A 1999-04-30 2000-04-30 Diagnostic sequencing by a combination of specific cleavage and mass spectrometry IL145607A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13198499P 1999-04-30 1999-04-30
PCT/EP2000/003904 WO2000066771A2 (en) 1999-04-30 2000-04-30 Diagnostic sequencing by a combination of specific cleavage and mass spectrometry

Publications (1)

Publication Number Publication Date
IL145607A0 true IL145607A0 (en) 2002-06-30

Family

ID=22451891

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14560700A IL145607A0 (en) 1999-04-30 2000-04-30 Diagnostic sequencing by a combination of specific cleavage and mass spectrometry

Country Status (9)

Country Link
EP (1) EP1173622B1 (no)
JP (2) JP5615997B2 (no)
AT (1) ATE298004T1 (no)
AU (1) AU779112B2 (no)
CA (1) CA2370872C (no)
DE (1) DE60020830T2 (no)
IL (1) IL145607A0 (no)
NO (1) NO20015293L (no)
WO (1) WO2000066771A2 (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT410983B (de) * 2001-09-14 2003-09-25 Huber Christian G Dr Verfahren zur ermittlung der sequenz von nukleinsäuren
JP4151317B2 (ja) 2002-06-07 2008-09-17 日本電気株式会社 プロテオーム解析方法、プロテオーム解析システム、およびプロテオーム解析プログラム
JP4786904B2 (ja) * 2002-11-27 2011-10-05 セクエノム，インコーポレイティド 配列変化検出及び発見用の断片化をベースとする方法及びシステム
US7584058B2 (en) * 2003-02-27 2009-09-01 Methexis Genomics N.V. Genetic diagnosis using multiple sequence variant analysis
US9394565B2 (en) * 2003-09-05 2016-07-19 Agena Bioscience, Inc. Allele-specific sequence variation analysis
CA2561381C (en) 2004-03-26 2015-05-12 Sequenom, Inc. Base specific cleavage of methylation-specific amplification products in combination with mass analysis
AU2005233598B2 (en) 2004-04-09 2010-09-30 Trustees Of Boston University Method for De novo detection of sequences in nucleic acids:target sequencing by fragmentation
US7785843B2 (en) 2004-06-23 2010-08-31 Sequenom, Inc. Target-specific compomers and methods of use
CN101203528A (zh) 2005-03-15 2008-06-18 基因创新有限公司 对核苷类似物敏感性降低的乙型肝炎病毒变异体及其用途
EP1762629B1 (en) 2005-09-12 2009-11-11 Roche Diagnostics GmbH Detection of biological DNA
EP2527474A1 (en) 2006-10-20 2012-11-28 Innogenetics N.V. Methodology for analysis of sequence variations within the HCV NS3/4A genomic region
US10150990B2 (en) * 2008-04-21 2018-12-11 Roche Molecular Systems, Inc. Ribonucleotide tag nucleic acid detection
US8476013B2 (en) 2008-09-16 2013-07-02 Sequenom, Inc. Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
US8962247B2 (en) 2008-09-16 2015-02-24 Sequenom, Inc. Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses
EP3660165B1 (en) 2009-12-22 2023-01-04 Sequenom, Inc. Processes and kits for identifying aneuploidy
ES2930180T3 (es) 2012-03-02 2022-12-07 Sequenom Inc Métodos para enriquecer ácido nucleico canceroso a partir de una muestra biológica
US9920361B2 (en) 2012-05-21 2018-03-20 Sequenom, Inc. Methods and compositions for analyzing nucleic acid
JP2015521862A (ja) 2012-07-13 2015-08-03 セクエノム， インコーポレイテッド 非侵襲性の出生前診断に有用な母体サンプル由来の胎児核酸のメチル化に基づく富化のためのプロセスおよび組成物
EP2971100A1 (en) 2013-03-13 2016-01-20 Sequenom, Inc. Primers for dna methylation analysis
WO2015138774A1 (en) 2014-03-13 2015-09-17 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
WO2020145754A1 (ko) * 2019-01-11 2020-07-16 주식회사 진캐스트 유전자 변이 특이성이 증가된 dna 중합효소를 이용한 질량분석법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5288644A (en) * 1990-04-04 1994-02-22 The Rockefeller University Instrument and method for the sequencing of genome
US5436143A (en) * 1992-12-23 1995-07-25 Hyman; Edward D. Method for enzymatic synthesis of oligonucleotides
EP0690870A4 (en) * 1993-03-24 1998-05-20 Molecular Biology Resources DINUCLEOTIDE RESTRICTION ENDONUCLEASE PREPARATIONS AND METHOD FOR USE THEREOF
JP3637572B2 (ja) * 1995-03-27 2005-04-13 旭化成ファーマ株式会社 酵素による核酸の定量方法および定量用組成物
US5869242A (en) * 1995-09-18 1999-02-09 Myriad Genetics, Inc. Mass spectrometry to assess DNA sequence polymorphisms
CA2248084A1 (en) * 1996-03-04 1997-09-12 Genetrace Systems, Inc. Methods of screening nucleic acids using mass spectrometry
US20030129589A1 (en) * 1996-11-06 2003-07-10 Hubert Koster Dna diagnostics based on mass spectrometry
WO1998054571A1 (en) * 1997-05-28 1998-12-03 The Walter And Eliza Hall Institute Of Medical Research Nucleic acid diagnostics based on mass spectrometry or mass separation and base specific cleavage

Also Published As

Publication number Publication date
JP2014221072A (ja) 2014-11-27
WO2000066771A3 (en) 2001-02-08
JP2002542838A (ja) 2002-12-17
NO20015293D0 (no) 2001-10-29
EP1173622A2 (en) 2002-01-23
EP1173622B1 (en) 2005-06-15
WO2000066771A2 (en) 2000-11-09
CA2370872C (en) 2007-02-06
DE60020830T2 (de) 2006-07-27
NO20015293L (no) 2001-12-20
DE60020830D1 (de) 2005-07-21
AU779112B2 (en) 2005-01-06
CA2370872A1 (en) 2000-11-09
ATE298004T1 (de) 2005-07-15
AU5523600A (en) 2000-11-17
JP5615997B2 (ja) 2014-10-29

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