IL145536A0 - Site-specific isotopically-labeled proteins, amino acids, and biochemical precursors therefor - Google Patents

Site-specific isotopically-labeled proteins, amino acids, and biochemical precursors therefor

Info

Publication number
IL145536A0
IL145536A0 IL14553600A IL14553600A IL145536A0 IL 145536 A0 IL145536 A0 IL 145536A0 IL 14553600 A IL14553600 A IL 14553600A IL 14553600 A IL14553600 A IL 14553600A IL 145536 A0 IL145536 A0 IL 145536A0
Authority
IL
Israel
Prior art keywords
site
amino acids
labeled proteins
precursors therefor
biochemical precursors
Prior art date
Application number
IL14553600A
Other languages
English (en)
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of IL145536A0 publication Critical patent/IL145536A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/08Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489Metalloendopeptidases (3.4.24)
    • C12N9/6491Matrix metalloproteases [MMP's], e.g. interstitial collagenase (3.4.24.7); Stromelysins (3.4.24.17; 3.2.1.22); Matrilysin (3.4.24.23)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/001Acyclic or carbocyclic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1075General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of amino acids or peptide residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/13Labelling of peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/06Alanine; Leucine; Isoleucine; Serine; Homoserine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/08Lysine; Diaminopimelic acid; Threonine; Valine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05Isotopically modified compounds, e.g. labelled
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
IL14553600A 1999-04-09 2000-04-07 Site-specific isotopically-labeled proteins, amino acids, and biochemical precursors therefor IL145536A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28951799A 1999-04-09 1999-04-09
PCT/US2000/009296 WO2000061525A1 (en) 1999-04-09 2000-04-07 Site-specific isotopically-labeled proteins, amino acids, and biochemical precursors therefor

Publications (1)

Publication Number Publication Date
IL145536A0 true IL145536A0 (en) 2002-06-30

Family

ID=23111884

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14553600A IL145536A0 (en) 1999-04-09 2000-04-07 Site-specific isotopically-labeled proteins, amino acids, and biochemical precursors therefor
IL145536A IL145536A (en) 1999-04-09 2001-09-21 Site-specific isotopically-labeled proteins, amino acids and biochemical precursors therefor and their preparation

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL145536A IL145536A (en) 1999-04-09 2001-09-21 Site-specific isotopically-labeled proteins, amino acids and biochemical precursors therefor and their preparation

Country Status (29)

Country Link
EP (1) EP1169282B1 (es)
JP (1) JP2002541228A (es)
KR (1) KR100708225B1 (es)
CN (1) CN1244521C (es)
AR (1) AR029747A1 (es)
AT (1) ATE296789T1 (es)
AU (1) AU777749B2 (es)
BG (1) BG106043A (es)
BR (1) BR0009664A (es)
CA (1) CA2368652C (es)
CO (1) CO5160349A1 (es)
CZ (1) CZ20013616A3 (es)
DE (1) DE60020547T2 (es)
DK (1) DK1169282T3 (es)
ES (1) ES2243251T3 (es)
HK (1) HK1044753B (es)
HU (1) HUP0200809A3 (es)
IL (2) IL145536A0 (es)
MX (1) MXPA01010183A (es)
NO (1) NO20014691L (es)
NZ (1) NZ514518A (es)
PL (1) PL350889A1 (es)
PT (1) PT1169282E (es)
SI (1) SI1169282T1 (es)
SK (1) SK14322001A3 (es)
TR (1) TR200102842T2 (es)
TW (1) TWI283659B (es)
WO (1) WO2000061525A1 (es)
ZA (1) ZA200107919B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9708228B2 (en) 2010-01-06 2017-07-18 Commissariat A L'energie Atomique Et Aux Energies Alternatives Process for the specific isotopic labeling of methyl groups of Val, Leu and Ile
US10053396B2 (en) 2010-01-06 2018-08-21 Commissariat A L'energie Atomique Et Aux Energies Alternatives Process for the specific isotopic labeling of methyl groups of Val, Leu and Ile
KR101219684B1 (ko) * 2012-04-27 2013-01-10 건국대학교 산학협력단 정량적 질량분석기법을 이용한 만성골수성 백혈병의 발병 진단방법과 약제 내성 진단방법
EP2695873B1 (en) * 2012-08-08 2016-10-26 Commissariat A L'energie Atomique Et Aux Energies Alternatives Labeled chiral alpha-hydroxy ketoacid derivatives, a process for preparing said derivatives and their use
CN107793209A (zh) * 2016-08-30 2018-03-13 泰生科技香港有限公司 稳定性同位素标记植物的专用培养基、其制备方法及用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5698401A (en) * 1995-11-14 1997-12-16 Abbott Laboratories Use of nuclear magnetic resonance to identify ligands to target biomolecules

Also Published As

Publication number Publication date
NO20014691L (no) 2001-12-10
CN1353678A (zh) 2002-06-12
PT1169282E (pt) 2005-10-31
CN1244521C (zh) 2006-03-08
AR029747A1 (es) 2003-07-16
EP1169282A1 (en) 2002-01-09
DE60020547D1 (de) 2005-07-07
BR0009664A (pt) 2002-01-08
TWI283659B (en) 2007-07-11
KR20010108475A (ko) 2001-12-07
CA2368652C (en) 2009-11-10
TR200102842T2 (tr) 2002-03-21
IL145536A (en) 2010-05-31
SK14322001A3 (sk) 2002-02-05
ZA200107919B (en) 2003-03-26
HK1044753B (zh) 2006-03-24
KR100708225B1 (ko) 2007-04-17
SI1169282T1 (en) 2005-10-31
WO2000061525A1 (en) 2000-10-19
CZ20013616A3 (cs) 2002-04-17
HUP0200809A2 (en) 2002-06-29
CA2368652A1 (en) 2000-10-19
HK1044753A1 (en) 2002-11-01
AU777749B2 (en) 2004-10-28
PL350889A1 (en) 2003-02-10
HUP0200809A3 (en) 2004-11-29
DE60020547T2 (de) 2006-05-04
NO20014691D0 (no) 2001-09-27
NZ514518A (en) 2003-10-31
EP1169282B1 (en) 2005-06-01
BG106043A (en) 2002-05-31
MXPA01010183A (es) 2003-07-21
ES2243251T3 (es) 2005-12-01
AU4212100A (en) 2000-11-14
CO5160349A1 (es) 2002-05-30
DK1169282T3 (da) 2005-10-03
JP2002541228A (ja) 2002-12-03
ATE296789T1 (de) 2005-06-15

Similar Documents

Publication Publication Date Title
GB9703681D0 (en) Protein complemention
GB9719879D0 (en) Protein
HK1039158A1 (zh) Nlk1相互作用蛋白
EP1186615A4 (en) PROTEIN AND DNA OF THIS PROTEIN
EP1018551A4 (en) MEGSINE PROTEIN
HUP0200809A2 (en) Site-specific isotopically-labeled proteins, amino acids, and biochemical precursors therefor
IL139873A0 (en) Angoistatin-binding protein
IL143052A0 (en) Mammalian chondromodulin-like protein
GB9828704D0 (en) Proteins
GB9816337D0 (en) Proteins
GB9828880D0 (en) Protein
EP1142999A4 (en) PROTEIN AND ITS DNA
EP1111047A4 (en) NEW PROTEIN AND ITS DNA
EP1127066A4 (en) MODIFIED PROTEINS
GB9819038D0 (en) Protein
GB9809566D0 (en) Protein
GB9812607D0 (en) Protein
EP1132472A4 (en) NEW PROTEIN AND ITS APPLICATION
GB9816335D0 (en) Proteins
GB9816336D0 (en) Proteins
GB0315759D0 (en) Proteins
EP1101821A4 (en) NEW PROTEIN AND ITS DNA
GB9816096D0 (en) Protein
GB9823975D0 (en) Protein
SI1088069T1 (en) Angiostatin-binding protein