IL145490A0 - Treatment with small peptides to effect antifibrotic activity - Google Patents
Treatment with small peptides to effect antifibrotic activityInfo
- Publication number
- IL145490A0 IL145490A0 IL14549000A IL14549000A IL145490A0 IL 145490 A0 IL145490 A0 IL 145490A0 IL 14549000 A IL14549000 A IL 14549000A IL 14549000 A IL14549000 A IL 14549000A IL 145490 A0 IL145490 A0 IL 145490A0
- Authority
- IL
- Israel
- Prior art keywords
- fibrosis
- phe
- tyr
- adhesions
- mammal
- Prior art date
Links
- 230000003510 anti-fibrotic effect Effects 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 230000000694 effects Effects 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 206010016654 Fibrosis Diseases 0.000 abstract 5
- 230000004761 fibrosis Effects 0.000 abstract 4
- 238000001356 surgical procedure Methods 0.000 abstract 4
- 241000124008 Mammalia Species 0.000 abstract 2
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 241001647372 Chlamydia pneumoniae Species 0.000 abstract 1
- 241001269524 Dura Species 0.000 abstract 1
- GKZIWHRNKRBEOH-HOTGVXAUSA-N Phe-Phe Chemical group C([C@H]([NH3+])C(=O)N[C@@H](CC=1C=CC=CC=1)C([O-])=O)C1=CC=CC=C1 GKZIWHRNKRBEOH-HOTGVXAUSA-N 0.000 abstract 1
- FSXRLASFHBWESK-HOTGVXAUSA-N Phe-Tyr Chemical group C([C@H](N)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(O)=O)C1=CC=CC=C1 FSXRLASFHBWESK-HOTGVXAUSA-N 0.000 abstract 1
- 206010060932 Postoperative adhesion Diseases 0.000 abstract 1
- CGWAPUBOXJWXMS-HOTGVXAUSA-N Tyr-Phe Chemical group C([C@H](N)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C1=CC=C(O)C=C1 CGWAPUBOXJWXMS-HOTGVXAUSA-N 0.000 abstract 1
- 238000012084 abdominal surgery Methods 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 230000007882 cirrhosis Effects 0.000 abstract 1
- 208000019425 cirrhosis of liver Diseases 0.000 abstract 1
- 208000029078 coronary artery disease Diseases 0.000 abstract 1
- FSXRLASFHBWESK-UHFFFAOYSA-N dipeptide phenylalanyl-tyrosine Chemical group C=1C=C(O)C=CC=1CC(C(O)=O)NC(=O)C(N)CC1=CC=CC=C1 FSXRLASFHBWESK-UHFFFAOYSA-N 0.000 abstract 1
- 210000003238 esophagus Anatomy 0.000 abstract 1
- 206010061989 glomerulosclerosis Diseases 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 208000014674 injury Diseases 0.000 abstract 1
- 210000000936 intestine Anatomy 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000005036 nerve Anatomy 0.000 abstract 1
- 210000003101 oviduct Anatomy 0.000 abstract 1
- 231100000915 pathological change Toxicity 0.000 abstract 1
- 230000036285 pathological change Effects 0.000 abstract 1
- 210000000578 peripheral nerve Anatomy 0.000 abstract 1
- 108010073025 phenylalanylphenylalanine Chemical group 0.000 abstract 1
- 230000002980 postoperative effect Effects 0.000 abstract 1
- 208000005069 pulmonary fibrosis Diseases 0.000 abstract 1
- 230000001954 sterilising effect Effects 0.000 abstract 1
- 238000004659 sterilization and disinfection Methods 0.000 abstract 1
- 210000002435 tendon Anatomy 0.000 abstract 1
- 230000008733 trauma Effects 0.000 abstract 1
- 125000001493 tyrosinyl group Chemical group [H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 abstract 1
- 210000003708 urethra Anatomy 0.000 abstract 1
- 210000001177 vas deferen Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/07—Tetrapeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurology (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12551499P | 1999-03-22 | 1999-03-22 | |
| PCT/US2000/007411 WO2000056349A1 (en) | 1999-03-22 | 2000-03-20 | Treatment with small peptides to effect antifibrotic activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL145490A0 true IL145490A0 (en) | 2002-06-30 |
Family
ID=22420066
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL14549000A IL145490A0 (en) | 1999-03-22 | 2000-03-20 | Treatment with small peptides to effect antifibrotic activity |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20020072499A1 (pl) |
| EP (1) | EP1162990B1 (pl) |
| JP (2) | JP4021147B2 (pl) |
| KR (1) | KR100699509B1 (pl) |
| CN (1) | CN1348381A (pl) |
| AT (1) | ATE413184T1 (pl) |
| AU (1) | AU3765100A (pl) |
| BR (1) | BR0009226A (pl) |
| CA (1) | CA2367048A1 (pl) |
| DE (1) | DE60040730D1 (pl) |
| EA (1) | EA200100997A1 (pl) |
| ES (1) | ES2316359T3 (pl) |
| HK (1) | HK1045649A1 (pl) |
| IL (1) | IL145490A0 (pl) |
| MX (1) | MXPA01009504A (pl) |
| NO (1) | NO20014594L (pl) |
| PL (1) | PL203758B1 (pl) |
| WO (1) | WO2000056349A1 (pl) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7604633B2 (en) | 1996-04-12 | 2009-10-20 | Cytyc Corporation | Moisture transport system for contact electrocoagulation |
| US8551082B2 (en) | 1998-05-08 | 2013-10-08 | Cytyc Surgical Products | Radio-frequency generator for powering an ablation device |
| BR0012495A (pt) * | 1999-07-16 | 2002-06-11 | Histatek Llc | Métodos para o tratamento de uma indicação resultante de uma resposta mediada por ige em um mamìfero, para a regulação descendente de um receptor para ige e de ligante cd40, e, para a inibição da secreção de ige por plasmócitos |
| US7731712B2 (en) | 2004-12-20 | 2010-06-08 | Cytyc Corporation | Method and system for transcervical tubal occlusion |
| US7674260B2 (en) * | 2005-04-28 | 2010-03-09 | Cytyc Corporation | Emergency hemostasis device utilizing energy |
| US8486060B2 (en) | 2006-09-18 | 2013-07-16 | Cytyc Corporation | Power ramping during RF ablation |
| US7846160B2 (en) | 2006-12-21 | 2010-12-07 | Cytyc Corporation | Method and apparatus for sterilization |
| RU2366369C1 (ru) * | 2008-04-23 | 2009-09-10 | Государственное учреждение Научный центр реконструктивной и восстановительной хирургии Восточно-Сибирского научного центра Сибирского отделения Российской Академии медицинских наук | Способ микрохирургической декомпрессии большеберцового нерва при тарзальном тоннельном синдроме у больных сахарным диабетом |
| CN114463249B (zh) * | 2021-11-24 | 2024-04-05 | 杭州医派智能科技有限公司 | 一种基于深度学习的用于评估肾小球周围组织纤维化的辅助方法、计算机设备 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002516820A (ja) * | 1997-11-13 | 2002-06-11 | ヒスタテク・エルエルシー | 低分子量ペプチド及び喘息及び炎症の治療方法 |
-
2000
- 2000-03-20 AT AT00916561T patent/ATE413184T1/de active
- 2000-03-20 IL IL14549000A patent/IL145490A0/xx unknown
- 2000-03-20 ES ES00916561T patent/ES2316359T3/es not_active Expired - Lifetime
- 2000-03-20 WO PCT/US2000/007411 patent/WO2000056349A1/en not_active Ceased
- 2000-03-20 MX MXPA01009504A patent/MXPA01009504A/es active IP Right Grant
- 2000-03-20 PL PL350860A patent/PL203758B1/pl not_active IP Right Cessation
- 2000-03-20 EA EA200100997A patent/EA200100997A1/ru unknown
- 2000-03-20 CN CN00806666A patent/CN1348381A/zh active Pending
- 2000-03-20 BR BR0009226-6A patent/BR0009226A/pt not_active Application Discontinuation
- 2000-03-20 EP EP00916561A patent/EP1162990B1/en not_active Expired - Lifetime
- 2000-03-20 HK HK02107077.9A patent/HK1045649A1/zh unknown
- 2000-03-20 JP JP2000606253A patent/JP4021147B2/ja not_active Expired - Fee Related
- 2000-03-20 AU AU37651/00A patent/AU3765100A/en not_active Abandoned
- 2000-03-20 DE DE60040730T patent/DE60040730D1/de not_active Expired - Lifetime
- 2000-03-20 CA CA002367048A patent/CA2367048A1/en not_active Abandoned
- 2000-03-20 KR KR1020017012064A patent/KR100699509B1/ko not_active Expired - Fee Related
-
2001
- 2001-09-21 NO NO20014594A patent/NO20014594L/no not_active Application Discontinuation
- 2001-09-21 US US09/960,720 patent/US20020072499A1/en not_active Abandoned
-
2007
- 2007-01-19 JP JP2007009831A patent/JP2007131635A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR100699509B1 (ko) | 2007-03-26 |
| NO20014594D0 (no) | 2001-09-21 |
| JP2002539270A (ja) | 2002-11-19 |
| EA200100997A1 (ru) | 2002-02-28 |
| BR0009226A (pt) | 2001-12-26 |
| CA2367048A1 (en) | 2000-09-28 |
| DE60040730D1 (de) | 2008-12-18 |
| PL203758B1 (pl) | 2009-11-30 |
| WO2000056349A1 (en) | 2000-09-28 |
| NO20014594L (no) | 2001-11-21 |
| EP1162990A1 (en) | 2001-12-19 |
| JP4021147B2 (ja) | 2007-12-12 |
| ES2316359T3 (es) | 2009-04-16 |
| MXPA01009504A (es) | 2003-08-19 |
| CN1348381A (zh) | 2002-05-08 |
| EP1162990A4 (en) | 2002-02-06 |
| KR20010109316A (ko) | 2001-12-08 |
| US20020072499A1 (en) | 2002-06-13 |
| JP2007131635A (ja) | 2007-05-31 |
| EP1162990B1 (en) | 2008-11-05 |
| HK1045649A1 (zh) | 2002-12-06 |
| PL350860A1 (en) | 2003-02-10 |
| ATE413184T1 (de) | 2008-11-15 |
| AU3765100A (en) | 2000-10-09 |
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