IL141639A - Multicomponent vaccines - Google Patents

Multicomponent vaccines

Info

Publication number
IL141639A
IL141639A IL14163999A IL14163999A IL141639A IL 141639 A IL141639 A IL 141639A IL 14163999 A IL14163999 A IL 14163999A IL 14163999 A IL14163999 A IL 14163999A IL 141639 A IL141639 A IL 141639A
Authority
IL
Israel
Prior art keywords
proteins
fragments
fragment
protein
bacterial
Prior art date
Application number
IL14163999A
Other languages
English (en)
Other versions
IL141639A0 (en
Original Assignee
Inhibitex Inc
Texas A & M Univ Sys
Trinity College Dublin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inhibitex Inc, Texas A & M Univ Sys, Trinity College Dublin filed Critical Inhibitex Inc
Publication of IL141639A0 publication Critical patent/IL141639A0/xx
Publication of IL141639A publication Critical patent/IL141639A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1275—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Streptococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/085—Staphylococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1271—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Toxicology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL14163999A 1998-08-31 1999-08-31 Multicomponent vaccines IL141639A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9843998P 1998-08-31 1998-08-31
PCT/US1999/019727 WO2000012131A1 (fr) 1998-08-31 1999-08-31 Vaccins a plusieurs constituants

Publications (2)

Publication Number Publication Date
IL141639A0 IL141639A0 (en) 2002-03-10
IL141639A true IL141639A (en) 2005-12-18

Family

ID=22269290

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14163999A IL141639A (en) 1998-08-31 1999-08-31 Multicomponent vaccines

Country Status (13)

Country Link
EP (1) EP1109577B1 (fr)
JP (2) JP2002523473A (fr)
KR (1) KR100644953B1 (fr)
CN (1) CN1314450C (fr)
AT (1) ATE422368T1 (fr)
AU (1) AU771426B2 (fr)
BR (1) BR9913340A (fr)
CA (2) CA2777661C (fr)
DE (1) DE69940404D1 (fr)
ES (1) ES2322409T3 (fr)
IL (1) IL141639A (fr)
MX (1) MXPA01002119A (fr)
WO (1) WO2000012131A1 (fr)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6692739B1 (en) 1998-08-31 2004-02-17 Inhibitex, Inc. Staphylococcal immunotherapeutics via donor selection and donor stimulation
JP4714342B2 (ja) 1998-08-31 2011-06-29 ザ プラヴアスト フエロウス アンド スカラース オブ ザ カレツヂ オブ ザ ハリー アンド アンデイヴアイデツド トリニテイ オブ クイーン エリザベス ニヤー ダブリン コアグラーゼ陰性スタフィロコカス菌に由来のポリペプチド及びポリヌクレオチド
WO2000012132A1 (fr) * 1998-08-31 2000-03-09 Inhibitex, Inc. Procede d'immunotherapie contre les infections staphylococciques comprenant la selection des donneurs et la stimulation des donneurs
GB0014907D0 (en) * 2000-06-20 2000-08-09 Univ Sheffield Antigenic polypeptides
CA2425000A1 (fr) * 2000-10-20 2002-05-02 Inhibitex, Inc. Anticorps monoclonaux diriges contre la proteine map et procede d'utilisation de ceux-ci dans le traitement ou la prevention des infections
EP1481011A4 (fr) * 2002-03-05 2007-05-30 Inhibitex Inc Anticorps monoclonaux et polyclonaux reconnaissant des proteines staphylocoques a coagulase negative
WO2004080490A2 (fr) 2003-03-07 2004-09-23 Wyeth Holdings Corporation Conjugues de proteine-polysaccharide porteuse d'adhesine superficielle staphylococcique pour immunisation contre des infections nosocomiales
WO2004094600A2 (fr) * 2003-04-16 2004-11-04 The Texas A & M University System Proteine efb issue de staphylococcus aureus et region de liaison a c3 inhibant l'activation du complement
WO2004110367A2 (fr) * 2003-05-29 2004-12-23 Inhibitex, Inc. Proteines sdr du staphylocoque capitis et utilisation associee dans la prevention et le traitement d'infections
BRPI0515520A (pt) * 2004-09-22 2008-07-29 Glaxosmithkline Biolog Sa composição imunogênica, vacina, métodos de preparar uma vacina e de prevenir ou tratar infecção estafilocócica, e, uso de composição imunogênica
US7829294B2 (en) * 2004-12-28 2010-11-09 Daiichi Pure Chemicals Co., Ltd. Anti-human soluble fibrin monoclonal antibody and immunological assay method using the antibody
GB0526038D0 (en) 2005-12-21 2006-02-01 Glaxosmithkline Biolog Sa Immunogenic composition
EP2368570A3 (fr) * 2006-01-18 2012-05-02 University Of Chicago Compositions et procédés liés aux protéines des bactéries staphylocoques
US20100021503A1 (en) * 2006-03-30 2010-01-28 Glaxosmithkline Biologicals S.A. Immunogenic composition
CA2693239A1 (fr) * 2007-07-23 2009-01-29 Vaccine Research International Plc Vaccin a cellules entieres staphylococciques inactivees
US9181329B2 (en) 2007-08-31 2015-11-10 The University Of Chicago Methods and compositions related to immunizing against Staphylococcal lung diseases and conditions
EP2666784B1 (fr) 2007-08-31 2017-04-05 University Of Chicago Méthodes et compositions associées à l'immunisation contre des maladies et d'affections pulmonaires staphylococciques
WO2009111337A1 (fr) 2008-03-03 2009-09-11 Irm Llc Composés et compositions servant de modulateurs de l’activité des tlr
WO2010014304A1 (fr) 2008-07-29 2010-02-04 University Of Chicago Compositions et procédés apparentés à des protéines de bactérie staphylococcique
EP2414387B1 (fr) 2009-04-03 2015-12-16 University Of Chicago Compositions et méthodes associées aux variants de la protéine a (spa)
AU2010258677B2 (en) 2009-06-10 2016-10-06 Glaxosmithkline Biologicals S.A. Benzonaphthyridine-containing vaccines
RU2536981C9 (ru) 2009-06-22 2015-05-10 ВАЙЕТ ЭлЭлСи Иммуногенные композиции антигенов staphylococcus aureus
SA114350400B1 (ar) 2009-06-22 2016-05-26 ويث ال ال سي تركيبات وطرق لتحضير تركيبات مولدة للمناعة لمقترن بولي سكاريد كبسولي للنمط المصلي 5 و 8 من المكورات العنقودية الذهبية
AU2010271582B2 (en) 2009-07-15 2016-07-28 Aimm Therapeutics B.V. Gram-positive bacteria specific binding compounds
DK2459216T3 (da) 2009-09-02 2013-12-09 Novartis Ag Immunogene sammensætninger omfattende tlr-aktivitetsmodulatorer
JO3257B1 (ar) 2009-09-02 2018-09-16 Novartis Ag مركبات وتركيبات كمعدلات لفاعلية tlr
WO2011057148A1 (fr) 2009-11-05 2011-05-12 Irm Llc Composés et compositions permettant de moduler l'activité des tlr-7
SG10201501980SA (en) 2009-12-15 2015-05-28 Novartis Ag Homogeneous suspension of immunopotentiating compounds and uses thereof
CA2792938C (fr) 2010-03-23 2018-07-31 Irm Llc Composes (lipopeptides a base de cysteine) et compositions en tant qu'agonistes des tlr2 utilises pour traiter des infections, inflammations, maladies respiratoires entre autres
CN103037885B (zh) 2010-07-02 2015-08-26 芝加哥大学 与蛋白A(SpA)变体相关的组合物和方法
US9192661B2 (en) 2010-07-06 2015-11-24 Novartis Ag Delivery of self-replicating RNA using biodegradable polymer particles
PL3150222T3 (pl) * 2010-12-22 2020-05-18 Wyeth Llc Stabilne immunogenne kompozycje antygenów staphylococcus aureus
US8945588B2 (en) 2011-05-06 2015-02-03 The University Of Chicago Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides
EP2848257A4 (fr) * 2012-05-07 2015-12-02 Mogam Biotechnology Inst Composition de vaccin pour prévenir une infection par staphylococcus aureus
WO2014118305A1 (fr) 2013-02-01 2014-08-07 Novartis Ag Administration intradermique de compositions immunologiques comprenant des agonistes des récepteurs de type toll
MX2017007652A (es) * 2014-12-10 2017-10-11 Glaxosmithkline Biologicals Sa Metodo de tratamiento.
CN107007832A (zh) * 2016-01-28 2017-08-04 中创云牧科技咨询(北京)股份有限公司 一种ClfA-A靶位的金黄色葡萄球菌奶牛乳房炎疫苗的制备方法
CA3090271A1 (fr) 2018-02-12 2019-08-15 Inimmune Corporation Ligands du recepteur de type toll
KR102528412B1 (ko) * 2020-09-08 2023-05-04 클립스비엔씨 주식회사 신규한 포도상구균 감염 질환의 예방 또는 치료용 조성물
CA3198924A1 (fr) 2020-11-04 2022-05-12 Eligo Bioscience Particules derivees de phages pour l'administration in situ de charge utile d'adn dans une population de c. acnes

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5189015A (en) * 1984-05-30 1993-02-23 Alfa-Laval Agri International Ab Method for prophylactic treatment of the colonization of a Staphylococcus aureus bacterial strain by bacterial cell surface protein with fibronectin and fibrinogen binding ability
SE454403B (sv) * 1984-05-30 1988-05-02 Alfa Laval Agri Int Anvendning av ett cellyteprotein med fibronektin-, fibrinogen-, kollagen-, och/eller lamininbindande egenskaper vid framstellning av sarbehandlingsmedel
US5730978A (en) * 1989-09-01 1998-03-24 Fred Hutchinson Cancer Research Center Inhibition of lymphocyte adherence with α4β1-specific antibodies
US5440014A (en) * 1990-08-10 1995-08-08 H+E,Uml/Oo/ K; Magnus Fibronectin binding peptide
US5851794A (en) * 1990-10-22 1998-12-22 Alfa Laval Ab Collagen binding protein as well as its preparation
US5648240A (en) * 1994-05-24 1997-07-15 Texas A&M University MHC II analog from Staphylococcus aureus
US6288214B1 (en) * 1996-05-16 2001-09-11 Texas A&M University Systems Collagen binding protein compositions and methods of use
SE9602496D0 (sv) * 1996-06-20 1996-06-20 Bengt Guss Method and means for producing a fibrinogen binding protein and its use in biotechnology
AU744723B2 (en) * 1997-01-21 2002-02-28 The Texas A & M University System Fibronectin binding protein compositions, and methods of use
AU1537699A (en) * 1997-11-26 1999-06-15 Bioresearch Ireland a division of Eolas - The Irish Science and Technology Agency Extracellular matrix-binding proteins from (staphylococcus aureus)

Also Published As

Publication number Publication date
CA2340304A1 (fr) 2000-03-09
AU5588999A (en) 2000-03-21
ES2322409T3 (es) 2009-06-19
KR20010085745A (ko) 2001-09-07
DE69940404D1 (de) 2009-03-26
CA2340304C (fr) 2012-12-04
CA2777661C (fr) 2014-10-21
CN1317976A (zh) 2001-10-17
AU771426B2 (en) 2004-03-18
JP2011168607A (ja) 2011-09-01
WO2000012131A1 (fr) 2000-03-09
JP2002523473A (ja) 2002-07-30
EP1109577B1 (fr) 2009-02-11
ATE422368T1 (de) 2009-02-15
EP1109577A1 (fr) 2001-06-27
IL141639A0 (en) 2002-03-10
KR100644953B1 (ko) 2006-11-10
JP5460642B2 (ja) 2014-04-02
CA2777661A1 (fr) 2000-03-09
CN1314450C (zh) 2007-05-09
MXPA01002119A (es) 2003-03-27
BR9913340A (pt) 2001-11-06
EP1109577A4 (fr) 2002-03-13

Similar Documents

Publication Publication Date Title
IL141639A0 (en) Multicomponent vaccines
WO2002072600A3 (fr) Anticorps monoclonaux contre la proteine clfa et procede d'utilisation dans le traitement et la prevention d'infections
WO1999027109A3 (fr) PROTEINES LIANT LA MATRICE EXTRACELLULAIRE ISSUES DU $i(STAPHILOCOCCUS AUREUS)
AU3126097A (en) Collagen binding protein compositions and methods of use
EP1203817A3 (fr) Composés et procédés pour l'immunothérapie et le diagnostic de la tuberculose
WO2001052791A3 (fr) Complexes de fragments de liaison peptidique de proteines de choc thermique et leur utilisation comme agents immmunotherapeutiques
HUP9901186A2 (hu) Peptid-és adjuvánsalapú gyógyszerkészítmény immunmodulációra
AU2002305450A1 (en) Proteomimetic compounds and methods
EP1731166A3 (fr) Protéines et vaccins de streptococcus pneumoniae
GB0103169D0 (en) Vaccine composition
WO2002075507A3 (fr) Preparations de vaccin anti-bacteriennes
DE69914911D1 (de) Pharmazeutische präparate zur bekämpfung oder prophylaxe von mikroorganismen infizierten oberflächen
WO2000061724A3 (fr) Compositions vaccinales anti-bacteriennes
DE69728975D1 (de) Rekombinante phagen
WO2021158755A3 (fr) Protéines leptospirales et leurs utilisations
GB9723945D0 (en) Tissue cement
WO2000063386A3 (fr) Prevention, diagnostic et traitement de la maladie de lyme
EP1574579A3 (fr) Protéines de membranes externes, leurs gènes, et leur utilisation
WO2002057281A3 (fr) Aminoglycosides utilises comme antibiotiques
DE60024977D1 (de) Klonierung und expression von haemophilus somnus transferrin-bindenden proteinen
NO20042711L (no) Fremgangsmate for a behandle bakterielle infeksjoner ved anvendelse av gemifloksasin eller et salt derav et betalaktamantibiotikum
WO2002077648A3 (fr) Antigenes vaccinaux de nesseria pathogenes et commensaux
WO2003072607A8 (fr) Anticorps monoclonaux a reaction croisee contre des proteines de liaison de collagene bacterien
AU2002224437A1 (en) Monoclonal antibodies to the map protein and method of use in treating or preventing infections
CA2171369A1 (fr) Utilisation d'aggressines d'agents pathogenes permettant d'ameliorer l'administration liposomique d'antibiotiques et (ou) de vaccins

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
KB Patent renewed
EXP Patent expired