IL140993A0 - Trypsin substrate and diagnostic device, and method of using same - Google Patents

Trypsin substrate and diagnostic device, and method of using same

Info

Publication number
IL140993A0
IL140993A0 IL14099301A IL14099301A IL140993A0 IL 140993 A0 IL140993 A0 IL 140993A0 IL 14099301 A IL14099301 A IL 14099301A IL 14099301 A IL14099301 A IL 14099301A IL 140993 A0 IL140993 A0 IL 140993A0
Authority
IL
Israel
Prior art keywords
same
diagnostic device
trypsin substrate
trypsin
substrate
Prior art date
Application number
IL14099301A
Other languages
English (en)
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IL140993A0 publication Critical patent/IL140993A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/30—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to nitro or nitroso groups
    • C07C279/32—N-nitroguanidines
    • C07C279/36—Substituted N-nitroguanidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/36—Oxygen atoms in position 3, e.g. adrenochrome
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL14099301A 2000-05-15 2001-01-19 Trypsin substrate and diagnostic device, and method of using same IL140993A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20399900P 2000-05-15 2000-05-15

Publications (1)

Publication Number Publication Date
IL140993A0 true IL140993A0 (en) 2002-02-10

Family

ID=22756189

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14099301A IL140993A0 (en) 2000-05-15 2001-01-19 Trypsin substrate and diagnostic device, and method of using same

Country Status (9)

Country Link
US (1) US6770764B2 (xx)
EP (1) EP1157984A3 (xx)
JP (1) JP5016752B2 (xx)
AU (1) AU785019B2 (xx)
CA (1) CA2334827A1 (xx)
IL (1) IL140993A0 (xx)
NO (1) NO20012307L (xx)
NZ (1) NZ509863A (xx)
ZA (1) ZA200102450B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7419665B2 (en) * 2003-10-16 2008-09-02 Siemens Healthcare Diagnostics Inc. Monoclonal antibodies for detection of urinary trypsin inhibitors
GB2435510A (en) * 2006-02-23 2007-08-29 Mologic Ltd Enzyme detection product and methods
EP2160478B1 (en) * 2007-06-06 2014-08-27 Siemens Healthcare Diagnostics Inc. Predictive diagnostics for kidney disease
US20150369747A1 (en) 2011-07-15 2015-12-24 Siemens Healthcare Diagnostics Inc. Device and method for detection of humidity-compromised urine test strips
DK3050974T3 (en) 2009-01-26 2019-02-18 Siemens Healthcare Diagnostics Inc Procedure for Detecting Moisture Compromised Urine Test Strips
CN115872919A (zh) * 2022-12-28 2023-03-31 吉林医药学院 一种3-(n-对甲苯磺酰基-l-丙氨酰氧基)吲哚的转晶方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3552928A (en) 1967-07-19 1971-01-05 Miles Lab Whole blood separation means and test system using same
DE2118455B1 (de) 1971-04-16 1972-09-21 Boehringer Mannheim Gmbh Teststreifen
DE2158124C3 (de) 1971-11-24 1975-03-13 Boehringer Mannheim Gmbh, 6800 Mannheim Verwendung von Polyamidvlies oder -filz als saugfähiger Träger für diagnostische Mittel
US4128540A (en) * 1972-05-25 1978-12-05 Parke, Davis & Company Pyroglutamyl-histidyl-tryptophanyl-seryl-tyrosyl hydrazides
US3846247A (en) 1972-09-27 1974-11-05 Warner Lambert Co Moisture barrier
US4046513A (en) 1976-06-30 1977-09-06 Miles Laboratories, Inc. Printed reagent test devices and method of making same
US4046514A (en) 1976-11-24 1977-09-06 Miles Laboratories, Inc. Test device and method for determining a component in a sample
HU181009B (en) * 1980-01-18 1983-05-30 Richter Gedeon Vegyeszet Process for preparing angiotensin-ii analogues with antagonictic activity containing in position 1 sarcosyl,hydroxyacetyl or l-alpha-aminoxy-propionyl group and in positiona 8 esteric group
DE3017721A1 (de) 1980-05-09 1981-11-26 Boehringer Mannheim Gmbh, 6800 Mannheim Mittel zum nachweis esterolytischer und/oder proteolytischer enzyme und dafuer geeignete substrate
US4774340A (en) 1984-04-06 1988-09-27 Miles Inc. Method for preparing 3-hydroxy pyrroles and esters thereof
US4704460A (en) 1984-04-06 1987-11-03 Miles Laboratories, Inc. Novel compounds for detecting the presence of hydrolytic analytes in a test sample
US4645842A (en) 1984-04-06 1987-02-24 Miles Laboratories, Inc. Pyrrole compounds for detecting the presence of hydrolytic analytes
US4657855A (en) 1984-04-06 1987-04-14 Miles Laboratories, Inc. Composition and test device for determining the presence of leukocytes, esterase and protease in a test sample
US4717658A (en) 1985-12-03 1988-01-05 Miles Inc. Gram negative bacteria screening method with horseshoe crab amebocyte lysate (LAL)
US5175089A (en) * 1988-07-15 1992-12-29 The Trustees Of Columbia University In The City Of New York Method for monitoring periodontal disease by monitoring endotoxins and inflammatory agents
JPH0578391A (ja) * 1991-09-12 1993-03-30 Hitachi Chem Co Ltd ペプチドおよびその塩
JPH05140195A (ja) * 1991-11-12 1993-06-08 Hitachi Chem Co Ltd ペプチドおよびその塩
JPH06228189A (ja) * 1993-01-06 1994-08-16 Fuji Photo Film Co Ltd ペプチド誘導体およびその用途
US5422341A (en) * 1993-08-06 1995-06-06 Ohmeda Pharmaceutical Products Division Inc. Motilin-like polypeptides with gastrointestinal motor stimulating activity
US5750405A (en) 1996-03-01 1998-05-12 Bayer Corporation Method for the detection for protein
BR9708021A (pt) 1996-03-11 1999-07-27 Bayer Ag Proteína substancialmente purificada composição farmacêutica sequência de ácido nucleico isolada vetor de express o de protéina auto-replicante e processos para inibir a atividade de protéinas de serina tratar uma condição e preparar um medicamento de uma proteína
KR980010425A (ko) * 1996-07-30 1998-04-30 안홍원 뇨중 백혈구 및 단백질 분해 효소 검출을 위한 조성물 및 측정기구
JP3626982B2 (ja) 1997-08-29 2005-03-09 アークレイ株式会社 タンパク質分解酵素阻害物質の測定方法およびそれに用いる測定キット

Also Published As

Publication number Publication date
EP1157984A3 (en) 2004-01-02
NO20012307D0 (no) 2001-05-10
JP2002069055A (ja) 2002-03-08
EP1157984A2 (en) 2001-11-28
CA2334827A1 (en) 2001-11-15
NO20012307L (no) 2001-11-16
US6770764B2 (en) 2004-08-03
AU2121301A (en) 2001-11-22
JP5016752B2 (ja) 2012-09-05
NZ509863A (en) 2002-09-27
ZA200102450B (en) 2001-09-28
AU785019B2 (en) 2006-08-24
US20020004219A1 (en) 2002-01-10

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