IL140918A0 - Improved transformation efficiency in phage display through modification of a coat protein - Google Patents
Improved transformation efficiency in phage display through modification of a coat proteinInfo
- Publication number
- IL140918A0 IL140918A0 IL14091899A IL14091899A IL140918A0 IL 140918 A0 IL140918 A0 IL 140918A0 IL 14091899 A IL14091899 A IL 14091899A IL 14091899 A IL14091899 A IL 14091899A IL 140918 A0 IL140918 A0 IL 140918A0
- Authority
- IL
- Israel
- Prior art keywords
- modification
- phage display
- transformation efficiency
- coat protein
- improved transformation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/10011—Details dsDNA Bacteriophages
- C12N2795/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/10011—Details dsDNA Bacteriophages
- C12N2795/10041—Use of virus, viral particle or viral elements as a vector
- C12N2795/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9429198P | 1998-07-27 | 1998-07-27 | |
US10351498P | 1998-10-08 | 1998-10-08 | |
US13329699P | 1999-05-10 | 1999-05-10 | |
US13487099P | 1999-05-19 | 1999-05-19 | |
PCT/US1999/016596 WO2000006717A2 (en) | 1998-07-27 | 1999-07-22 | Improved transformation efficiency in phage display through modification of a coat protein |
Publications (1)
Publication Number | Publication Date |
---|---|
IL140918A0 true IL140918A0 (en) | 2002-02-10 |
Family
ID=27492720
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14091899A IL140918A0 (en) | 1998-07-27 | 1999-07-22 | Improved transformation efficiency in phage display through modification of a coat protein |
Country Status (7)
Country | Link |
---|---|
US (1) | US8685893B2 (ja) |
EP (1) | EP1100890A2 (ja) |
JP (1) | JP2002522029A (ja) |
AU (1) | AU5122499A (ja) |
CA (1) | CA2334170A1 (ja) |
IL (1) | IL140918A0 (ja) |
WO (1) | WO2000006717A2 (ja) |
Families Citing this family (28)
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EP1100890A2 (en) | 1998-07-27 | 2001-05-23 | Genentech, Inc. | Improved transformation efficiency in phage display through modification of a coat protein |
JP2004512010A (ja) * | 2000-03-29 | 2004-04-22 | ディージーアイ・バイオテクノロジーズ・エル・エル・シー | インスリン及びigf−1受容体のアゴニスト及びアンタゴニスト |
DE10129815A1 (de) * | 2001-06-24 | 2003-01-09 | Profos Ag | Verfahren zur Aufreinigung von Bakterienzellen und Zellbestandteilen |
US7112435B1 (en) * | 2002-08-07 | 2006-09-26 | Ambit Biosciences Corporation | Uncoupling of DNA insert propagation and expression of protein for phage display |
EP2305710A3 (en) | 2002-06-03 | 2013-05-29 | Genentech, Inc. | Synthetic antibody phage libraries |
KR20050044886A (ko) | 2002-07-05 | 2005-05-13 | 데니스 르클레르 | 면역보조 바이러스 입자 |
US8101189B2 (en) | 2002-07-05 | 2012-01-24 | Folia Biotech Inc. | Vaccines and immunopotentiating compositions and methods for making and using them |
US7897381B2 (en) * | 2002-08-07 | 2011-03-01 | Ambit Biosciences Corporation | Uncoupling of DNA insert propagation and expression of protein for phage display |
US7833741B2 (en) | 2002-08-07 | 2010-11-16 | Ambit Biosciences Corporation | Uncoupling of DNA insert propagation and expression of protein for phage display |
US20060122377A1 (en) | 2004-02-19 | 2006-06-08 | Genentech, Inc. | CDR-repaired antibodies |
EP2465870A1 (en) | 2005-11-07 | 2012-06-20 | Genentech, Inc. | Binding polypeptides with diversified and consensus VH/VL hypervariable sequences |
ES2385261T3 (es) | 2006-04-10 | 2012-07-20 | Genentech, Inc. | Moduladores de PDZ Disheveled |
MX366269B (es) | 2011-09-30 | 2019-07-04 | Chugai Pharmaceutical Co Ltd | Biblioteca de moleculas de union dependientes de la concentracion ionica. |
CA2851371A1 (en) | 2011-10-14 | 2013-04-18 | Genentech, Inc. | Zymogen activators |
CN103974709B (zh) | 2011-10-14 | 2016-12-14 | 霍夫曼-拉罗奇有限公司 | Bace1的肽抑制剂 |
CN104254541A (zh) | 2012-03-16 | 2014-12-31 | 弗·哈夫曼-拉罗切有限公司 | 改造的构象稳定蛋白质 |
US9139863B2 (en) | 2012-03-16 | 2015-09-22 | Genentech, Inc. | Engineered conformationally-stabilized proteins |
TWI652279B (zh) | 2013-11-11 | 2019-03-01 | 中外製藥股份有限公司 | 含改變的抗體可變區之抗原結合分子 |
US11473080B2 (en) | 2014-04-30 | 2022-10-18 | The Board Of Trustees Of The University Of Illinois | Method for generating high affinity, bivalent binding agents for sandwich assays |
US11034992B2 (en) | 2016-03-23 | 2021-06-15 | The General Hospital Corporation | Assays and methods for detecting UDP-glucose |
CA3046561A1 (en) | 2016-12-12 | 2018-06-21 | Hurrah S.A R.L. | Compositions and methods for increasing the immunoglobulin binding capacities of immunoglobulin-binding polypeptides and oligopeptides |
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US11492645B2 (en) | 2018-08-29 | 2022-11-08 | Shanghaitech University | Composition and use of Cas protein inhibitors |
US11454347B2 (en) | 2020-04-01 | 2022-09-27 | Texas Smart Solutions, LLC | Collapsible stand and cover |
CN116249774A (zh) | 2020-05-26 | 2023-06-09 | 迪奥尼斯治疗公司 | 核酸人工微型蛋白质组文库 |
WO2022167396A1 (en) | 2021-02-02 | 2022-08-11 | Biocopy Gmbh | Method for identifying emerging pathogen mutations enabling host cell entry and immune evasion |
WO2023076733A1 (en) | 2021-11-01 | 2023-05-04 | Dana-Farber Cancer Institute, Inc. | Biologically selected nucleic acid artificial mini-proteome libraries |
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-
1999
- 1999-07-22 EP EP99935837A patent/EP1100890A2/en not_active Withdrawn
- 1999-07-22 CA CA002334170A patent/CA2334170A1/en not_active Abandoned
- 1999-07-22 WO PCT/US1999/016596 patent/WO2000006717A2/en active Application Filing
- 1999-07-22 AU AU51224/99A patent/AU5122499A/en not_active Abandoned
- 1999-07-22 JP JP2000562499A patent/JP2002522029A/ja active Pending
- 1999-07-22 IL IL14091899A patent/IL140918A0/xx unknown
-
2008
- 2008-07-28 US US12/181,222 patent/US8685893B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
WO2000006717A9 (en) | 2000-11-16 |
CA2334170A1 (en) | 2000-02-10 |
EP1100890A2 (en) | 2001-05-23 |
US8685893B2 (en) | 2014-04-01 |
AU5122499A (en) | 2000-02-21 |
WO2000006717A2 (en) | 2000-02-10 |
JP2002522029A (ja) | 2002-07-23 |
US20120165226A1 (en) | 2012-06-28 |
WO2000006717A3 (en) | 2000-06-29 |
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