IL140174A - Device for organic cell cultures and for studying their electrophysiological activity and membrane used in said device - Google Patents
Device for organic cell cultures and for studying their electrophysiological activity and membrane used in said deviceInfo
- Publication number
- IL140174A IL140174A IL14017499A IL14017499A IL140174A IL 140174 A IL140174 A IL 140174A IL 14017499 A IL14017499 A IL 14017499A IL 14017499 A IL14017499 A IL 14017499A IL 140174 A IL140174 A IL 140174A
- Authority
- IL
- Israel
- Prior art keywords
- support
- cells
- electrophysiological activity
- studying
- cell cultures
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/4833—Physical analysis of biological material of solid biological material, e.g. tissue samples, cell cultures
- G01N33/4836—Physical analysis of biological material of solid biological material, e.g. tissue samples, cell cultures using multielectrode arrays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/04—Flat or tray type, drawers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
- C12M25/02—Membranes; Filters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/46—Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Optics & Photonics (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Clinical Laboratory Science (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9807596A FR2779443B1 (fr) | 1998-06-08 | 1998-06-08 | Dispositif de culture de cellules organiques et d'etude de leur activite electrophysiologique et membrane utilisee dans un tel dispositif |
PCT/CH1999/000243 WO1999064559A2 (fr) | 1998-06-08 | 1999-06-04 | Dispositif de culture de cellules organiques et d'etude de leur activite electrophysiologique et membrane utilisee dans un tel dispositif |
Publications (2)
Publication Number | Publication Date |
---|---|
IL140174A0 IL140174A0 (en) | 2002-02-10 |
IL140174A true IL140174A (en) | 2003-12-10 |
Family
ID=9527465
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14017499A IL140174A (en) | 1998-06-08 | 1999-06-04 | Device for organic cell cultures and for studying their electrophysiological activity and membrane used in said device |
Country Status (10)
Country | Link |
---|---|
US (1) | US6689594B1 (xx) |
EP (1) | EP1133691B1 (xx) |
JP (1) | JP2002517225A (xx) |
AT (1) | ATE236399T1 (xx) |
AU (1) | AU4027999A (xx) |
DE (1) | DE69906574T2 (xx) |
ES (1) | ES2195572T3 (xx) |
FR (1) | FR2779443B1 (xx) |
IL (1) | IL140174A (xx) |
WO (1) | WO1999064559A2 (xx) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7485454B1 (en) * | 2000-03-10 | 2009-02-03 | Bioprocessors Corp. | Microreactor |
IL136232A0 (en) * | 2000-05-18 | 2001-05-20 | Bar Ilan University Res Author | Measurements of enzymatic activity in a single, individual cell in population |
JP3570715B2 (ja) | 2001-06-05 | 2004-09-29 | 松下電器産業株式会社 | マルチ電極を備えた信号検出用センサ |
JP4192097B2 (ja) * | 2001-10-25 | 2008-12-03 | バル−イラン ユニバーシティ | 相互作用型透明個別細胞バイオチッププロセッサー |
JP4370082B2 (ja) * | 2002-08-26 | 2009-11-25 | 独立行政法人科学技術振興機構 | 神経細胞培養マイクロチャンバー |
IL154677A0 (en) | 2003-02-27 | 2003-09-17 | Univ Bar Ilan | A method and apparatus for manipulating an individual cell |
US9200245B2 (en) | 2003-06-26 | 2015-12-01 | Seng Enterprises Ltd. | Multiwell plate |
US8597597B2 (en) * | 2003-06-26 | 2013-12-03 | Seng Enterprises Ltd. | Picoliter well holding device and method of making the same |
WO2004113492A1 (en) * | 2003-06-26 | 2004-12-29 | Molecular Cytomics Ltd. | Improved materials for constructing cell-chips, cell-chip covers, cell-chip coats, processed cell-chips and uses thereof |
US7888110B2 (en) | 2003-06-26 | 2011-02-15 | Seng Enterprises Ltd. | Pico liter well holding device and method of making the same |
WO2005008626A1 (en) * | 2003-07-11 | 2005-01-27 | University Of North Carolina At Chapel Hill | Methods and systems for controlling a computer using a video image and for combining the video image with a computer desktop |
US20050064524A1 (en) * | 2003-08-11 | 2005-03-24 | Mordechai Deutsch | Population of cells utilizable for substance detection and methods and devices using same |
PL1656449T3 (pl) | 2003-08-21 | 2009-08-31 | Monsanto Technology Llc | Desaturazy kwasów tłuszczowych z Primula |
BRPI0506610A (pt) * | 2004-02-03 | 2007-05-02 | Chemagis Ltd | montelucaste sódico amorfo, processo de preparação de montelucaste sódico amorfo, composição farmacêutica, método de tratamento utilizando a administração de montelucaste sódico amorfo, co-precipitado amorfo de montelucaste sódico e processo de preparação de co-precipitado amorfo de montelucaste sódico |
US7403647B2 (en) * | 2004-09-13 | 2008-07-22 | Seng Enterprises Ltd. | Method for identifying an image of a well in an image of a well-bearing component |
US20080063251A1 (en) * | 2004-07-07 | 2008-03-13 | Mordechai Deutsch | Method and Device for Identifying an Image of a Well in an Image of a Well-Bearing |
WO2006021959A2 (en) * | 2004-08-25 | 2006-03-02 | Seng Enterprises Ltd. | Method and device for isolating cells |
WO2006037527A1 (en) * | 2004-09-30 | 2006-04-13 | Pamgene Bv | Masked solid porous supports allowing fast and easy reagent exchange to accelerate electrode-based microarrays |
ES2352344T3 (es) | 2005-01-25 | 2011-02-17 | Seng Enterprises Limited | Dispositivo de microfluido para estudio de células. |
GB0512214D0 (en) * | 2005-06-15 | 2005-07-27 | Capsant Neurotechnologies Ltd | Method |
GB0512216D0 (en) * | 2005-06-15 | 2005-07-27 | Capsant Neurotechnologies Ltd | Device |
US20070141555A1 (en) * | 2005-10-11 | 2007-06-21 | Mordechai Deutsch | Current damper for the study of cells |
US8288120B2 (en) * | 2005-11-03 | 2012-10-16 | Seng Enterprises Ltd. | Method for studying floating, living cells |
US20060223999A1 (en) * | 2006-05-10 | 2006-10-05 | Chemagis Ltd. | Process for preparing montelukast and precursors thereof |
JP2009544947A (ja) * | 2006-07-24 | 2009-12-17 | バイオツァー エントヴィックルングス−ゲーエムベーハー | 細胞に関するオンライン測定のための装置 |
DE102007016629A1 (de) * | 2007-04-05 | 2008-10-09 | Micronas Gmbh | Sensor zur Erfassung eines toxischen oder gefährlichen Gasgemisches und Betriebsverfahren |
WO2009081409A2 (en) | 2007-12-26 | 2009-07-02 | Seng Enterprises Ltd. | Device for the study of living cells |
US9145540B1 (en) | 2007-11-15 | 2015-09-29 | Seng Enterprises Ltd. | Device for the study of living cells |
JP5200888B2 (ja) * | 2008-11-21 | 2013-06-05 | 大日本印刷株式会社 | パターン細胞培養用器具 |
JP5758989B2 (ja) * | 2011-04-28 | 2015-08-05 | 株式会社日立製作所 | 細胞培養容器および細胞培養装置 |
CN102680526B (zh) * | 2012-05-16 | 2014-07-02 | 清华大学 | 单细胞阵列微芯片及其制造、电测量和电穿孔方法 |
CN103630579A (zh) * | 2013-02-27 | 2014-03-12 | 中国科学院电子学研究所 | 细胞阻抗分析的芯片及仪器 |
EP4170014A1 (en) | 2021-10-21 | 2023-04-26 | Alpvision SA | Microfluidic system for robust long-term electrical measurement and/or stimulation of cell cultures |
WO2024145528A1 (en) * | 2022-12-29 | 2024-07-04 | The Board Of Trustees Of The Leland Stanford Junior University | Devices, systems and methods for electrophysical recordings of suspension cultures |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SU1124022A1 (ru) * | 1983-04-15 | 1984-11-15 | Специальное конструкторское бюро биологического приборостроения АН СССР | Камера дл регистрации электрофизиологических характеристик и фиксации потенциала мембраны биологического объекта |
US5563067A (en) * | 1994-06-13 | 1996-10-08 | Matsushita Electric Industrial Co., Ltd. | Cell potential measurement apparatus having a plurality of microelectrodes |
FR2733055B1 (fr) * | 1995-04-12 | 1997-12-19 | Chemodyne Sa | Nouveau dispositif d'etude de cultures organotypiques et ses applications en electrophysiologie |
US6303082B1 (en) * | 1999-12-15 | 2001-10-16 | Nanogen, Inc. | Permeation layer attachment chemistry and method |
-
1998
- 1998-06-08 FR FR9807596A patent/FR2779443B1/fr not_active Expired - Fee Related
-
1999
- 1999-06-04 US US09/701,956 patent/US6689594B1/en not_active Expired - Fee Related
- 1999-06-04 AT AT99923354T patent/ATE236399T1/de not_active IP Right Cessation
- 1999-06-04 WO PCT/CH1999/000243 patent/WO1999064559A2/fr active IP Right Grant
- 1999-06-04 JP JP2000553549A patent/JP2002517225A/ja active Pending
- 1999-06-04 ES ES99923354T patent/ES2195572T3/es not_active Expired - Lifetime
- 1999-06-04 EP EP99923354A patent/EP1133691B1/fr not_active Expired - Lifetime
- 1999-06-04 DE DE69906574T patent/DE69906574T2/de not_active Expired - Fee Related
- 1999-06-04 IL IL14017499A patent/IL140174A/xx not_active IP Right Cessation
- 1999-06-04 AU AU40279/99A patent/AU4027999A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE69906574T2 (de) | 2004-01-29 |
US6689594B1 (en) | 2004-02-10 |
AU4027999A (en) | 1999-12-30 |
IL140174A0 (en) | 2002-02-10 |
WO1999064559A2 (fr) | 1999-12-16 |
EP1133691A2 (fr) | 2001-09-19 |
EP1133691B1 (fr) | 2003-04-02 |
WO1999064559A3 (fr) | 2001-07-12 |
DE69906574D1 (de) | 2003-05-08 |
ES2195572T3 (es) | 2003-12-01 |
ATE236399T1 (de) | 2003-04-15 |
FR2779443B1 (fr) | 2000-08-04 |
JP2002517225A (ja) | 2002-06-18 |
FR2779443A1 (fr) | 1999-12-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |