IL138289A0 - Process for the production of purine derivatives - Google Patents

Process for the production of purine derivatives

Info

Publication number
IL138289A0
IL138289A0 IL13828999A IL13828999A IL138289A0 IL 138289 A0 IL138289 A0 IL 138289A0 IL 13828999 A IL13828999 A IL 13828999A IL 13828999 A IL13828999 A IL 13828999A IL 138289 A0 IL138289 A0 IL 138289A0
Authority
IL
Israel
Prior art keywords
12alkyl
formula
compound
production
hydrogen
Prior art date
Application number
IL13828999A
Other languages
English (en)
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of IL138289A0 publication Critical patent/IL138289A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/40Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/26Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32Nitrogen atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL13828999A 1998-04-02 1999-03-30 Process for the production of purine derivatives IL138289A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9807116.0A GB9807116D0 (en) 1998-04-02 1998-04-02 Novel process
PCT/EP1999/002309 WO1999051604A2 (en) 1998-04-02 1999-03-30 Process for the production of purine derivatives

Publications (1)

Publication Number Publication Date
IL138289A0 true IL138289A0 (en) 2001-10-31

Family

ID=10829765

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13828999A IL138289A0 (en) 1998-04-02 1999-03-30 Process for the production of purine derivatives

Country Status (16)

Country Link
US (1) US6437125B1 (https=)
EP (1) EP1068210B1 (https=)
JP (1) JP4459439B2 (https=)
KR (1) KR100613812B1 (https=)
CN (1) CN1125068C (https=)
AT (1) ATE268332T1 (https=)
AU (1) AU3605199A (https=)
BR (1) BR9908959A (https=)
CA (1) CA2323965A1 (https=)
DE (1) DE69917765T2 (https=)
DK (1) DK1068210T3 (https=)
ES (1) ES2222702T3 (https=)
GB (1) GB9807116D0 (https=)
IL (1) IL138289A0 (https=)
PT (1) PT1068210E (https=)
WO (1) WO1999051604A2 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60202245T2 (de) 2001-08-30 2005-09-01 Ajinomoto Co., Inc. Herstellungsmethode von Famciclovir und Herstellungs- bzw. Kristallisationsmethode eines entsprechenden Intermediates
AU2003268213A1 (en) * 2002-08-26 2004-03-11 Teva Pharmaceutical Industries Ltd. Crystalline solid famciclovir forms i, ii, iii and preparation thereof
US7473780B2 (en) * 2004-05-18 2009-01-06 Teva Pharmeceutical Industries Ltd. Drying process for preparing crystalline solid famciclovir
GB2426247A (en) * 2005-05-20 2006-11-22 Arrow Int Ltd Methods of preparing purine derivatives such as famciclovir
CN110386935A (zh) * 2018-04-20 2019-10-29 重庆常捷医药有限公司 一种泛昔洛韦中间体的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3485225D1 (de) * 1983-08-18 1991-12-05 Beecham Group Plc Antivirale guanin-derivate.
US5684153A (en) * 1984-08-16 1997-11-04 Beecham Group Plc Process for the preparation of purine derivatives
EP0182024B1 (en) * 1984-09-20 1991-04-03 Beecham Group Plc Purine derivatives and their pharmaceutical use
GB8817607D0 (en) 1988-07-23 1988-09-01 Beecham Group Plc Novel process
US5688948A (en) * 1991-09-18 1997-11-18 Ajinomoto Co., Inc. Process for isomerizing acyclic nucleosides and process for separating purine nucleosides
GB9407698D0 (en) * 1994-04-19 1994-06-15 Smithkline Beecham Plc Pharmaceuticals
EP0827960A1 (en) * 1996-09-10 1998-03-11 Ajinomoto Co., Inc. Process for producing purine derivatives

Also Published As

Publication number Publication date
PT1068210E (pt) 2004-10-29
WO1999051604A3 (en) 2000-02-17
CN1125068C (zh) 2003-10-22
CN1294591A (zh) 2001-05-09
AU3605199A (en) 1999-10-25
JP2002510692A (ja) 2002-04-09
DE69917765D1 (de) 2004-07-08
HK1035896A1 (en) 2001-12-14
ATE268332T1 (de) 2004-06-15
EP1068210A2 (en) 2001-01-17
DK1068210T3 (da) 2004-09-20
KR20010034701A (ko) 2001-04-25
KR100613812B1 (ko) 2006-08-18
ES2222702T3 (es) 2005-02-01
JP4459439B2 (ja) 2010-04-28
WO1999051604A2 (en) 1999-10-14
GB9807116D0 (en) 1998-06-03
CA2323965A1 (en) 1999-10-14
BR9908959A (pt) 2000-12-05
US6437125B1 (en) 2002-08-20
EP1068210B1 (en) 2004-06-02
DE69917765T2 (de) 2005-07-14

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees