IL137677A - Amino anthracyclinone derivatives, a process for their preparation and their use in the preparation of a medicament for the treatment of amyloidosis - Google Patents

Amino anthracyclinone derivatives, a process for their preparation and their use in the preparation of a medicament for the treatment of amyloidosis

Info

Publication number
IL137677A
IL137677A IL13767799A IL13767799A IL137677A IL 137677 A IL137677 A IL 137677A IL 13767799 A IL13767799 A IL 13767799A IL 13767799 A IL13767799 A IL 13767799A IL 137677 A IL137677 A IL 137677A
Authority
IL
Israel
Prior art keywords
preparation
amyloidosis
medicament
amino
treatment
Prior art date
Application number
IL13767799A
Other languages
English (en)
Other versions
IL137677A0 (en
Original Assignee
Pharmacia & Upjohn Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Spa filed Critical Pharmacia & Upjohn Spa
Publication of IL137677A0 publication Critical patent/IL137677A0/xx
Publication of IL137677A publication Critical patent/IL137677A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL13767799A 1998-03-10 1999-02-25 Amino anthracyclinone derivatives, a process for their preparation and their use in the preparation of a medicament for the treatment of amyloidosis IL137677A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9805080.0A GB9805080D0 (en) 1998-03-10 1998-03-10 Amino anthracyclinone derivatives
PCT/EP1999/001300 WO1999046254A2 (en) 1998-03-10 1999-02-25 Amino anthracyclinone derivatives and their use in the treatment of amyloidosis

Publications (2)

Publication Number Publication Date
IL137677A0 IL137677A0 (en) 2001-10-31
IL137677A true IL137677A (en) 2005-08-31

Family

ID=10828304

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13767799A IL137677A (en) 1998-03-10 1999-02-25 Amino anthracyclinone derivatives, a process for their preparation and their use in the preparation of a medicament for the treatment of amyloidosis

Country Status (23)

Country Link
US (1) US6268362B1 (id)
EP (1) EP1062206B1 (id)
JP (1) JP2002506066A (id)
KR (1) KR100603798B1 (id)
CN (1) CN1113867C (id)
AR (1) AR019831A1 (id)
AT (1) ATE264302T1 (id)
AU (1) AU755754B2 (id)
BR (1) BR9908057A (id)
CA (1) CA2321834A1 (id)
DE (1) DE69916438D1 (id)
EA (1) EA003333B1 (id)
GB (1) GB9805080D0 (id)
HU (1) HUP0101046A3 (id)
ID (1) ID26084A (id)
IL (1) IL137677A (id)
NO (1) NO317260B1 (id)
NZ (1) NZ506945A (id)
PL (1) PL193245B1 (id)
TW (1) TW528751B (id)
UA (1) UA51838C2 (id)
WO (1) WO1999046254A2 (id)
ZA (1) ZA991839B (id)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20110264A1 (it) * 2011-05-27 2012-11-28 Univ Degli Studi Milano Nuovi composti triciclici glicofusi, procedimento per la loro produzione e loro impiego quali ligandi dei peptidi ss amiloidi (ass).

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL110289A (en) 1993-08-06 1998-01-04 Policlinico San Matteo Istitut Pharmaceutical preparations containing 4-iodo-4-deoxydoxorubicin for the treatment of amyloidosis
GB9416007D0 (en) * 1994-08-08 1994-09-28 Erba Carlo Spa Anthracyclinone derivatives
GB9516349D0 (en) 1995-08-09 1995-10-11 Pharmacia Spa Aza-anthracyclinone derivatives
GB9613433D0 (en) 1996-06-26 1996-08-28 Pharmacia Spa Fluoro labelled anthracyclinone and anthracycline derivatives

Also Published As

Publication number Publication date
BR9908057A (pt) 2000-10-31
CA2321834A1 (en) 1999-09-16
EA003333B1 (ru) 2003-04-24
EP1062206A2 (en) 2000-12-27
TW528751B (en) 2003-04-21
ZA991839B (en) 1999-12-22
EA200000922A1 (ru) 2001-04-23
EP1062206B1 (en) 2004-04-14
UA51838C2 (uk) 2002-12-16
ID26084A (id) 2000-11-23
KR20010041737A (ko) 2001-05-25
CN1291977A (zh) 2001-04-18
KR100603798B1 (ko) 2006-07-25
JP2002506066A (ja) 2002-02-26
GB9805080D0 (en) 1998-05-06
NO317260B1 (no) 2004-09-27
WO1999046254A2 (en) 1999-09-16
AU755754B2 (en) 2002-12-19
DE69916438D1 (de) 2004-05-19
ATE264302T1 (de) 2004-04-15
HUP0101046A3 (en) 2002-12-28
AU2930899A (en) 1999-09-27
NZ506945A (en) 2002-06-28
IL137677A0 (en) 2001-10-31
PL344086A1 (en) 2001-09-24
PL193245B1 (pl) 2007-01-31
HUP0101046A2 (hu) 2001-08-28
WO1999046254A3 (en) 1999-10-21
NO20004406D0 (no) 2000-09-04
AR019831A1 (es) 2002-03-20
NO20004406L (no) 2000-10-30
CN1113867C (zh) 2003-07-09
US6268362B1 (en) 2001-07-31

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees