IL137178A0 - Il-18 receptors - Google Patents

Il-18 receptors

Info

Publication number
IL137178A0
IL137178A0 IL13717899A IL13717899A IL137178A0 IL 137178 A0 IL137178 A0 IL 137178A0 IL 13717899 A IL13717899 A IL 13717899A IL 13717899 A IL13717899 A IL 13717899A IL 137178 A0 IL137178 A0 IL 137178A0
Authority
IL
Israel
Prior art keywords
receptor
polypeptide
receptors
multimeric
fragment
Prior art date
Application number
IL13717899A
Other languages
English (en)
Original Assignee
Immunex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunex Corp filed Critical Immunex Corp
Publication of IL137178A0 publication Critical patent/IL137178A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
IL13717899A 1998-01-23 1999-01-22 Il-18 receptors IL137178A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US7230198P 1998-01-23 1998-01-23
US7883598P 1998-03-20 1998-03-20
US9446998P 1998-07-28 1998-07-28
PCT/US1999/001419 WO1999037772A1 (en) 1998-01-23 1999-01-22 Il-18 receptors

Publications (1)

Publication Number Publication Date
IL137178A0 true IL137178A0 (en) 2001-07-24

Family

ID=27372056

Family Applications (2)

Application Number Title Priority Date Filing Date
IL13717899A IL137178A0 (en) 1998-01-23 1999-01-22 Il-18 receptors
IL137178A IL137178A (en) 1998-01-23 2000-07-05 Il-18 receptors

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL137178A IL137178A (en) 1998-01-23 2000-07-05 Il-18 receptors

Country Status (13)

Country Link
US (4) US6589764B1 (de)
EP (1) EP1047781B1 (de)
JP (1) JP4271850B2 (de)
AT (1) ATE272114T1 (de)
AU (1) AU737592B2 (de)
CA (1) CA2318482C (de)
DE (1) DE69918946T2 (de)
DK (1) DK1047781T3 (de)
ES (1) ES2226335T3 (de)
IL (2) IL137178A0 (de)
NZ (1) NZ505880A (de)
PT (1) PT1047781E (de)
WO (1) WO1999037772A1 (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6326472B1 (en) 1997-10-15 2001-12-04 Schering Corporation Human receptor proteins; related reagents and methods
US6472179B2 (en) * 1998-09-25 2002-10-29 Regeneron Pharmaceuticals, Inc. Receptor based antagonists and methods of making and using
US7083949B2 (en) 1998-09-25 2006-08-01 Regeneron Pharmaceuticals, Inc. Receptor based antagonists and methods of making and using
US6927044B2 (en) 1998-09-25 2005-08-09 Regeneron Pharmaceuticals, Inc. IL-1 receptor based cytokine traps
US20020155526A1 (en) 1998-09-30 2002-10-24 Busfield Samantha J. Novel secreted immunomodulatory proteins and uses thereof
JP4741139B2 (ja) 1999-12-23 2011-08-03 ザイモジェネティクス， インコーポレイテッド 可溶性インターロイキン−２０レセプター
US7122632B2 (en) 1999-12-23 2006-10-17 Zymogenetics, Inc. Soluble Interleukin-20 receptor
US6610286B2 (en) 1999-12-23 2003-08-26 Zymogenetics, Inc. Method for treating inflammation using soluble receptors to interleukin-20
JP2004500086A (ja) * 2000-02-10 2004-01-08 アボット・ラボラトリーズ ヒトインターロイキン１８に結合する抗体とその調整方法および使用方法
US20020025317A1 (en) * 2000-07-20 2002-02-28 Schering Ag Bispecific monoclonal antibodies to IL-12 and IL-18
US20020052475A1 (en) * 2000-07-20 2002-05-02 Schering Ag High affinity soluble interleukin-18 receptor
EP1337636B1 (de) 2000-08-08 2006-10-18 ZymoGenetics, Inc. Lösliche zcyctor 11 cytokinrezeptoren
DE60121808T2 (de) 2000-09-15 2007-03-29 Zymogenetics, Inc., Seattle Verwendung eines polypeptids, welches die extrazelluläre domäne von il-20ra und il-20rb enthält, zur behandlung von entzündungen
AU2002211744B8 (en) * 2000-10-11 2008-03-20 Viron Therapeutics, Inc. Nucleic acid molecules and polypeptides for immune modulation
US7718368B2 (en) * 2000-12-04 2010-05-18 Viron Therapeutics Inc. Immunomodulatory protein and useful embodiments thereof
GB2375604A (en) * 2001-05-18 2002-11-20 Warner Lambert Co Methods for screening using interleukin soluble trimolecular complex
DK2270052T3 (en) 2001-06-26 2018-07-02 Amgen Inc Antibodies to OPGL
EP1293566A1 (de) 2001-09-17 2003-03-19 Societe Des Produits Nestle S.A. Ein löslicher Toll-ähnlicher Rezeptor
WO2003051384A1 (en) 2001-12-17 2003-06-26 Zymogenetics, Inc. Method for treating cervical cancer
JP2006508056A (ja) 2002-08-28 2006-03-09 イミュネックス・コーポレーション 心臓血管疾患を治療するための組成物および方法
WO2004032837A2 (en) 2002-10-08 2004-04-22 Ares Trading S.A. The use of cytokine able to bind il-18bp and of inhibiting the activity of a second cytokine
KR20050116392A (ko) 2003-03-24 2005-12-12 지모제넥틱스, 인코포레이티드 항-ｉｌ-22ｒａ 항체 및 결합 파트너 및 염증에 있어서의사용 방법
TWI353991B (en) 2003-05-06 2011-12-11 Syntonix Pharmaceuticals Inc Immunoglobulin chimeric monomer-dimer hybrids
US7968684B2 (en) * 2003-11-12 2011-06-28 Abbott Laboratories IL-18 binding proteins
US20050100965A1 (en) 2003-11-12 2005-05-12 Tariq Ghayur IL-18 binding proteins
US7393684B2 (en) 2003-11-21 2008-07-01 Zymogenetics, Inc. Immunoconjugates of anti-IL-20 antibodies and hybridoma cell lines expressing anti-IL-20 antibodies
US7141382B1 (en) 2004-10-12 2006-11-28 Parikh Chirag R Methods for detection of IL-18 as an early marker for diagnosis of acute renal failure and predictor of mortality
BRPI0516975A (pt) 2004-10-22 2008-09-30 Zymogenetics Inc anticorpo ou seu fragmento de ligação a antìgeno, composição farmacêutica, imunoconjugado, hibridoma, anticorpo monoclonal, e, uso de um anticorpo ou seu fragmento de ligação a antìgeno
EP1861423A4 (de) * 2005-02-15 2010-01-27 Apollo Life Sciences Ltd Moleküle und chimere moleküle davon
EP1987061A1 (de) * 2006-02-22 2008-11-05 University of Zurich Lösliche rezeptoren und verfahren zur behandlung von autoimmun- oder demyelinierenden krankheiten
WO2007147898A1 (en) 2006-06-22 2007-12-27 Novo Nordisk A/S Soluble heterodimeric receptors and uses thereof
CN101802197A (zh) * 2007-05-14 2010-08-11 比奥根艾迪克Ma公司 单链FC（ScFc）区、包含其的结合多肽及与其相关的方法
CL2008002153A1 (es) 2007-07-24 2009-06-05 Amgen Inc Anticuerpo aislado o fragmanto de unión de antigeno del mismo que se une al receptor de il-18 (il-18r); molecula de ácido nucleico codificante; celula huesped que la comprende; composición farmaceutica; uso médico para tratar o prevenir una condición asociada con il-18r; método in vitro para inhibir la unión de il-18 al il-18r.
BR112012021576A2 (pt) 2010-02-26 2016-10-25 Novo Nordisk As composições estáveis contendo anticorpo.
US20130136733A1 (en) 2010-05-28 2013-05-30 Novo Nordisk A/S Stable Multi-Dose Compositions Comprising an Antibody and a Preservative
AU2011274423B2 (en) * 2010-07-09 2016-02-11 Bioverativ Therapeutics Inc. Chimeric clotting factors
CA2805054A1 (en) 2010-08-25 2012-03-01 F. Hoffmann-La Roche Ag Antibodies against il-18r1 and uses thereof
JOP20200308A1 (ar) 2012-09-07 2017-06-16 Novartis Ag جزيئات إرتباط il-18

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989004838A1 (en) 1987-11-25 1989-06-01 Immunex Corporation Interleukin-1 receptors
EP0533006A1 (de) * 1991-09-18 1993-03-24 F.Hoffmann-La Roche & Co. Aktiengesellschaft Chimäre Interleukin 5-Rezeptor/Immunoglobulin-Polypeptide
US5470952A (en) 1993-10-20 1995-11-28 Regeneron Pharmaceuticals, Inc. CNTF and IL-6 antagonists
WO1996013593A2 (en) * 1994-10-26 1996-05-09 Procept, Inc. Soluble single chain t cell receptors
US5853721A (en) 1995-01-31 1998-12-29 Hoffmann-La Roche Inc. Antibody to interleukin-12 receptor
DK1243597T3 (da) * 1995-08-01 2008-09-22 Hoffmann La Roche Receptorer for det humane interleukin-12
US5776731A (en) 1996-02-21 1998-07-07 Immunex Corporation DNA encoding type-I interleukin-I receptor-like protein designated 2F1
US7141393B2 (en) 1996-12-26 2006-11-28 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Interleukin-18-receptor proteins
US6087116A (en) 1997-03-12 2000-07-11 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Interleukin-18 (IL-18) receptor polypeptides and their uses
US6326472B1 (en) 1997-10-15 2001-12-04 Schering Corporation Human receptor proteins; related reagents and methods
US6280955B1 (en) * 1997-12-16 2001-08-28 Tularik Inc. Interleukin-1 receptor accessory proteins, nucleic acids and methods
US6472179B2 (en) 1998-09-25 2002-10-29 Regeneron Pharmaceuticals, Inc. Receptor based antagonists and methods of making and using
US20020052475A1 (en) 2000-07-20 2002-05-02 Schering Ag High affinity soluble interleukin-18 receptor

Also Published As

Publication number Publication date
PT1047781E (pt) 2004-11-30
NZ505880A (en) 2003-06-30
IL137178A (en) 2007-06-17
US7704945B2 (en) 2010-04-27
US7169581B2 (en) 2007-01-30
CA2318482C (en) 2010-04-13
DK1047781T3 (da) 2004-12-06
WO1999037772A1 (en) 1999-07-29
AU2466899A (en) 1999-08-09
US20070135625A1 (en) 2007-06-14
DE69918946D1 (de) 2004-09-02
US20030199040A1 (en) 2003-10-23
ES2226335T3 (es) 2005-03-16
JP2002500886A (ja) 2002-01-15
US8053233B2 (en) 2011-11-08
DE69918946T2 (de) 2005-07-28
EP1047781B1 (de) 2004-07-28
US20100190211A1 (en) 2010-07-29
CA2318482A1 (en) 1999-07-29
JP4271850B2 (ja) 2009-06-03
US6589764B1 (en) 2003-07-08
AU737592B2 (en) 2001-08-23
EP1047781A1 (de) 2000-11-02
ATE272114T1 (de) 2004-08-15

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