IL137076A - Bipolytic-based imaging drugs for the treatment of blood clots - Google Patents

Bipolytic-based imaging drugs for the treatment of blood clots

Info

Publication number
IL137076A
IL137076A IL13707699A IL13707699A IL137076A IL 137076 A IL137076 A IL 137076A IL 13707699 A IL13707699 A IL 13707699A IL 13707699 A IL13707699 A IL 13707699A IL 137076 A IL137076 A IL 137076A
Authority
IL
Israel
Prior art keywords
bibapcitide
dicarboxylate
monocarboxylate
imaging
pharmaceutical compositions
Prior art date
Application number
IL13707699A
Other languages
English (en)
Hebrew (he)
Other versions
IL137076A0 (en
Original Assignee
Diatide Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9802681A external-priority patent/GB9802681D0/en
Application filed by Diatide Inc filed Critical Diatide Inc
Publication of IL137076A0 publication Critical patent/IL137076A0/xx
Publication of IL137076A publication Critical patent/IL137076A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
IL13707699A 1998-02-06 1999-02-05 Bipolytic-based imaging drugs for the treatment of blood clots IL137076A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/020,086 US6028056A (en) 1998-02-06 1998-02-06 Pharmaceutical compositions for imaging and treating thrombi
GB9802681A GB9802681D0 (en) 1998-02-06 1998-02-06 Pharmaceutical compoations for imaging and treating thrombi
PCT/US1999/002583 WO1999039747A1 (en) 1998-02-06 1999-02-05 Bipapcitide-based pharmaceutical compositions for imaging and treating thrombi

Publications (2)

Publication Number Publication Date
IL137076A0 IL137076A0 (en) 2001-06-14
IL137076A true IL137076A (en) 2004-08-31

Family

ID=26313082

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13707699A IL137076A (en) 1998-02-06 1999-02-05 Bipolytic-based imaging drugs for the treatment of blood clots

Country Status (26)

Country Link
US (1) US6028056A (xx)
EP (1) EP1053027B1 (xx)
JP (1) JP2003532617A (xx)
KR (1) KR100452390B1 (xx)
CN (1) CN1103606C (xx)
AR (1) AR018546A1 (xx)
AT (1) ATE279214T1 (xx)
AU (1) AU761778B2 (xx)
BR (1) BR9908352A (xx)
CA (1) CA2319544C (xx)
DE (1) DE69921096T2 (xx)
DK (1) DK1053027T3 (xx)
EA (1) EA005406B1 (xx)
ES (1) ES2229681T3 (xx)
HK (1) HK1032198A1 (xx)
HU (1) HUP0100887A3 (xx)
IL (1) IL137076A (xx)
NO (1) NO20003881D0 (xx)
NZ (1) NZ505085A (xx)
PE (1) PE20000250A1 (xx)
PL (1) PL342253A1 (xx)
PT (1) PT1053027E (xx)
SI (1) SI1053027T1 (xx)
SK (1) SK284463B6 (xx)
TW (1) TWI246425B (xx)
WO (1) WO1999039747A1 (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2744802T3 (pl) 2011-08-17 2017-07-31 Piramal Imaging Sa Związki do wiązania do glikoproteiny IIB/IIIA specyficznej wobec płytek i ich zastosowanie do obrazowania zakrzepów
WO2014124943A1 (en) 2013-02-12 2014-08-21 Bayer Pharma Aktiengesellschaft Metal chelate compounds for binding to the platelet specific glycoprotein iib/iiia

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5830856A (en) * 1991-02-08 1998-11-03 Diatide, Inc. Radiolabeled compounds for thrombus imaging
US5645815A (en) * 1991-02-08 1997-07-08 Diatide, Inc. Radiolabled compounds for thrombus imaging
US5508020A (en) * 1992-06-05 1996-04-16 Diatech, Inc. Technetium-99M labeled peptides for imaging
JP2941057B2 (ja) * 1992-05-21 1999-08-25 ダイアテク,インコーポレイテッド 血栓造影用のテクネチウム‐99m標識ペプチド

Also Published As

Publication number Publication date
HUP0100887A2 (hu) 2001-06-28
EA005406B1 (ru) 2005-02-24
JP2003532617A (ja) 2003-11-05
EA200000820A1 (ru) 2001-02-26
PE20000250A1 (es) 2000-06-02
ATE279214T1 (de) 2004-10-15
PT1053027E (pt) 2005-01-31
DE69921096D1 (de) 2004-11-18
NO20003881L (no) 2000-07-28
KR100452390B1 (ko) 2004-10-08
WO1999039747A1 (en) 1999-08-12
SK11392000A3 (sk) 2001-03-12
CA2319544A1 (en) 1999-08-12
BR9908352A (pt) 2000-11-28
DK1053027T3 (da) 2005-01-17
AU2660499A (en) 1999-08-23
ES2229681T3 (es) 2005-04-16
CN1103606C (zh) 2003-03-26
HK1032198A1 (en) 2001-07-13
SI1053027T1 (en) 2005-04-30
HUP0100887A3 (en) 2003-08-28
CA2319544C (en) 2006-07-04
SK284463B6 (sk) 2005-04-01
EP1053027A1 (en) 2000-11-22
AU761778B2 (en) 2003-06-12
NZ505085A (en) 2002-10-25
AR018546A1 (es) 2001-11-28
KR20010040676A (ko) 2001-05-15
IL137076A0 (en) 2001-06-14
US6028056A (en) 2000-02-22
DE69921096T2 (de) 2006-02-02
NO20003881D0 (no) 2000-07-28
EP1053027B1 (en) 2004-10-13
TWI246425B (en) 2006-01-01
CN1290179A (zh) 2001-04-04
PL342253A1 (en) 2001-06-04

Similar Documents

Publication Publication Date Title
JP3853354B2 (ja) 放射性標識ペプチドおよびタンパク質の自己放射線分解を防止する安定剤
US4427646A (en) Use of radiolabeled peptide derived from crosslinked fibrin to locate thrombi in vivo
US5371184A (en) Radiolabelled peptide compounds
JPH06507410A (ja) 心臓血管病変の検出
JPH07508289A (ja) 血栓造影用のテクネチウム‐99m標識ペプチド
JPH02502014A (ja) フィブリン結合性蛋白質を用いる血餅の診断方法
KR19980703560A (ko) 삼원 방사성 약물 착체
US7465434B2 (en) Diagnosis of blood clots using fibrin-binding proteins bound with contrast agents
JP2004523514A (ja) 造影剤として有用なフィブリン結合部分
US5879659A (en) Ternary radiopharmaceutical complexes
JP2007291134A (ja) 心臓血管および血栓の造影剤、方法、およびキット
EP1053027B1 (en) Bibapcitide-based pharmaceutical compositions for imaging and treating thrombi
EP0888130B1 (en) New ternary radiopharmaceutical complexes
JP3812680B2 (ja) 放射性医薬用途のペプチド類およびタンパク質類の安定化
MXPA00006545A (en) Bipapcitide-based pharmaceutical compositions for imaging and treating thrombi
CZ20002656A3 (cs) Farmaceutický prostředek na bázi bibapcitidinu pro léčení trombózy
Edenbrandt et al. Diagnosis of deep venous thrombosis by 99m Tc-human serum albumin microcolloid
SE2050786A1 (en) Novel compounds for use in diagnosis and/or monitoring of fibrosis
CA2185349C (en) Radiolabeled annexin-galactose conjugates
CN111377968A (zh) 一类含芳基硼酸的99mTc(Ⅲ)配合物及其药盒配方和应用
NO852664L (no) Radioaktivt diagnosemiddel for paavisning av venetrombose

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed