BR9908352A - Reagente precursor, e, composição farmacêutica - Google Patents

Reagente precursor, e, composição farmacêutica

Info

Publication number
BR9908352A
BR9908352A BR9908352-3A BR9908352A BR9908352A BR 9908352 A BR9908352 A BR 9908352A BR 9908352 A BR9908352 A BR 9908352A BR 9908352 A BR9908352 A BR 9908352A
Authority
BR
Brazil
Prior art keywords
precursor
pharmaceutical composition
precursor reagents
production
precursor reagent
Prior art date
Application number
BR9908352-3A
Other languages
English (en)
Inventor
Richard T Dean
John Lister-James
Original Assignee
Diatide Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9802681A external-priority patent/GB9802681D0/en
Application filed by Diatide Inc filed Critical Diatide Inc
Publication of BR9908352A publication Critical patent/BR9908352A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

''REAGENTE PRECURSOR, E, COMPOSIçãO FARMACEUTICA'' A invenção proporciona novos reagentes precursores usados na produção de agentes formadores de imagem derivados de apcitídeo. Agentes formadores de imagem preparados usando os reagentes precursores da invenção são úteis para detecção e diagnóstico in vivo de trombos. Os reagentes precursores da invenção também podem ser utilizados na produção de agentes antitrombóticos derivados de apcitídeo. A presença de três grupos carboxilato livres confere aos reagentes precursores solubilidade maior do que a bibapcitídeo em meios aquosos.
BR9908352-3A 1998-02-06 1999-02-05 Reagente precursor, e, composição farmacêutica BR9908352A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/020,086 US6028056A (en) 1998-02-06 1998-02-06 Pharmaceutical compositions for imaging and treating thrombi
GB9802681A GB9802681D0 (en) 1998-02-06 1998-02-06 Pharmaceutical compoations for imaging and treating thrombi
PCT/US1999/002583 WO1999039747A1 (en) 1998-02-06 1999-02-05 Bipapcitide-based pharmaceutical compositions for imaging and treating thrombi

Publications (1)

Publication Number Publication Date
BR9908352A true BR9908352A (pt) 2000-11-28

Family

ID=26313082

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9908352-3A BR9908352A (pt) 1998-02-06 1999-02-05 Reagente precursor, e, composição farmacêutica

Country Status (26)

Country Link
US (1) US6028056A (pt)
EP (1) EP1053027B1 (pt)
JP (1) JP2003532617A (pt)
KR (1) KR100452390B1 (pt)
CN (1) CN1103606C (pt)
AR (1) AR018546A1 (pt)
AT (1) ATE279214T1 (pt)
AU (1) AU761778B2 (pt)
BR (1) BR9908352A (pt)
CA (1) CA2319544C (pt)
DE (1) DE69921096T2 (pt)
DK (1) DK1053027T3 (pt)
EA (1) EA005406B1 (pt)
ES (1) ES2229681T3 (pt)
HK (1) HK1032198A1 (pt)
HU (1) HUP0100887A3 (pt)
IL (1) IL137076A (pt)
NO (1) NO20003881D0 (pt)
NZ (1) NZ505085A (pt)
PE (1) PE20000250A1 (pt)
PL (1) PL342253A1 (pt)
PT (1) PT1053027E (pt)
SI (1) SI1053027T1 (pt)
SK (1) SK284463B6 (pt)
TW (1) TWI246425B (pt)
WO (1) WO1999039747A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2744802T3 (pl) 2011-08-17 2017-07-31 Piramal Imaging Sa Związki do wiązania do glikoproteiny IIB/IIIA specyficznej wobec płytek i ich zastosowanie do obrazowania zakrzepów
WO2014124943A1 (en) 2013-02-12 2014-08-21 Bayer Pharma Aktiengesellschaft Metal chelate compounds for binding to the platelet specific glycoprotein iib/iiia

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5830856A (en) * 1991-02-08 1998-11-03 Diatide, Inc. Radiolabeled compounds for thrombus imaging
US5645815A (en) * 1991-02-08 1997-07-08 Diatide, Inc. Radiolabled compounds for thrombus imaging
US5508020A (en) * 1992-06-05 1996-04-16 Diatech, Inc. Technetium-99M labeled peptides for imaging
JP2941057B2 (ja) * 1992-05-21 1999-08-25 ダイアテク，インコーポレイテッド 血栓造影用のテクネチウム‐９９ｍ標識ペプチド

Also Published As

Publication number Publication date
HUP0100887A2 (hu) 2001-06-28
EA005406B1 (ru) 2005-02-24
JP2003532617A (ja) 2003-11-05
EA200000820A1 (ru) 2001-02-26
PE20000250A1 (es) 2000-06-02
ATE279214T1 (de) 2004-10-15
PT1053027E (pt) 2005-01-31
DE69921096D1 (de) 2004-11-18
NO20003881L (no) 2000-07-28
KR100452390B1 (ko) 2004-10-08
WO1999039747A1 (en) 1999-08-12
SK11392000A3 (sk) 2001-03-12
CA2319544A1 (en) 1999-08-12
DK1053027T3 (da) 2005-01-17
AU2660499A (en) 1999-08-23
ES2229681T3 (es) 2005-04-16
CN1103606C (zh) 2003-03-26
HK1032198A1 (en) 2001-07-13
SI1053027T1 (en) 2005-04-30
HUP0100887A3 (en) 2003-08-28
CA2319544C (en) 2006-07-04
SK284463B6 (sk) 2005-04-01
EP1053027A1 (en) 2000-11-22
AU761778B2 (en) 2003-06-12
NZ505085A (en) 2002-10-25
AR018546A1 (es) 2001-11-28
IL137076A (en) 2004-08-31
KR20010040676A (ko) 2001-05-15
IL137076A0 (en) 2001-06-14
US6028056A (en) 2000-02-22
DE69921096T2 (de) 2006-02-02
NO20003881D0 (no) 2000-07-28
EP1053027B1 (en) 2004-10-13
TWI246425B (en) 2006-01-01
CN1290179A (zh) 2001-04-04
PL342253A1 (en) 2001-06-04

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 9A E 10A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO1976 DE 18/11/2008.