BR0204494A - Composto, composição, sistema de reativos, utilização de um composto, processo de preparação do mesmo, e, método de medida do tempo de tromboplastina parcialmente ativada - Google Patents

Composto, composição, sistema de reativos, utilização de um composto, processo de preparação do mesmo, e, método de medida do tempo de tromboplastina parcialmente ativada

Info

Publication number
BR0204494A
BR0204494A BR0204494-3A BR0204494A BR0204494A BR 0204494 A BR0204494 A BR 0204494A BR 0204494 A BR0204494 A BR 0204494A BR 0204494 A BR0204494 A BR 0204494A
Authority
BR
Brazil
Prior art keywords
compound
composition
reactive system
preparation
partially activated
Prior art date
Application number
BR0204494-3A
Other languages
English (en)
Inventor
Jean-Paul Roisin
Stephane Steurs
Gerard Quentin
Original Assignee
Stago Diagnostica
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stago Diagnostica filed Critical Stago Diagnostica
Publication of BR0204494A publication Critical patent/BR0204494A/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/50—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/82—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C69/757—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
    • C07C69/88—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with esterified carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Polyethers (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fats And Perfumes (AREA)

Abstract

"COMPOSTO, COMPOSIçãO, SISTEMA DE REATIVOS, UTILIZAçãO DE UM COMPOSTO, PROCESSO DE PREPARAçãO DO MESMO, E, MéTODO DE MEDIDA DO TEMPO DE TROMBOPLASTINA PARCIALMENTE ATIVADA". A invenção tem por objeto ativadores contato para a via endógena da coagulação e sua utilização para explorar as anomalias da coagulação. Os ativadores da invenção são derivados de ácido gálico e preferivelmente galatos de polietileno glicol.
BR0204494-3A 2001-03-23 2002-03-22 Composto, composição, sistema de reativos, utilização de um composto, processo de preparação do mesmo, e, método de medida do tempo de tromboplastina parcialmente ativada BR0204494A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0103979A FR2822462B1 (fr) 2001-03-23 2001-03-23 Composes activateurs de la coagulation endogene utilisation pour l'exploration de la coagulation endogene
PCT/FR2002/001020 WO2002076921A1 (fr) 2001-03-23 2002-03-22 Derives de l'acide gallique et utilisation pour l'exploration de la coagulation endogene

Publications (1)

Publication Number Publication Date
BR0204494A true BR0204494A (pt) 2003-04-08

Family

ID=8861494

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0204494-3A BR0204494A (pt) 2001-03-23 2002-03-22 Composto, composição, sistema de reativos, utilização de um composto, processo de preparação do mesmo, e, método de medida do tempo de tromboplastina parcialmente ativada

Country Status (15)

Country Link
US (1) US7208266B2 (pt)
EP (1) EP1280758A1 (pt)
JP (1) JP4563648B2 (pt)
KR (1) KR20030005359A (pt)
CN (1) CN100432046C (pt)
AR (1) AR034221A1 (pt)
BR (1) BR0204494A (pt)
CA (1) CA2407779A1 (pt)
FR (1) FR2822462B1 (pt)
HK (1) HK1054737A1 (pt)
HU (1) HUP0302136A3 (pt)
MX (1) MXPA02011565A (pt)
PL (1) PL357449A1 (pt)
RU (1) RU2002131457A (pt)
WO (1) WO2002076921A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1581260B1 (en) * 2002-12-31 2014-09-17 Nektar Therapeutics Polymeric reagents comprising a ketone or a related functional group
DE102007062323A1 (de) * 2007-12-21 2009-06-25 Siemens Healthcare Diagnostics Products Gmbh Langzeitstabiles Thromboplastin-Reagenz
JP6577778B2 (ja) * 2015-07-30 2019-09-18 シスメックス株式会社 凝固時間の測定方法およびその装置、凝固時間測定用試薬ならびに試薬キット
CN105424945B (zh) * 2015-11-20 2018-05-18 重庆贝羿生物科技有限公司 一种凝血激活检测试剂及其制备方法与用途
KR101651605B1 (ko) * 2015-12-10 2016-08-26 대봉엘에스 주식회사 신규 페놀산류 유도체 화합물, 및 이의 용도
CN108344875B (zh) * 2017-01-22 2021-11-02 上海长岛生物技术有限公司 提高活化部分凝血活酶时间试剂对肝素敏感性的方法及用途
US20210405072A1 (en) * 2018-09-25 2021-12-30 Sekisui Medical Co., Ltd. Method for measuring blood coagulation time
CN110824154A (zh) * 2019-10-15 2020-02-21 常熟常江生物技术有限公司 用于血栓弹力图仪的激活剂
CN113679039B (zh) * 2021-05-12 2023-05-09 浙江大学 一种没食子酸聚乙二醇酯蛋白载体增效剂及其制备方法与应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1565823A (en) * 1976-11-11 1980-04-23 Pilkington Brothers Ltd Coating of glass fibres
JPS60199850A (ja) * 1984-03-26 1985-10-09 Eisai Co Ltd 新規な没食子酸誘導体
DE3544338A1 (de) * 1985-12-14 1987-06-19 Hoechst Ag Peptid-derivate mit inhibitorischer wirkung auf hydroxylierende enzyme, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung
CA1313997C (en) * 1986-04-11 1993-03-02 Hideo Anraku Accelerator of the activity of hydrolase
US4994192A (en) * 1990-01-16 1991-02-19 Eastman Kodak Company Amine polymers as coagulator accelerators in blood phase separation
US4979471A (en) * 1990-04-09 1990-12-25 Larry Hartshorn Animal confinement chute
WO1991016453A1 (en) * 1990-04-17 1991-10-31 Analytical Control Systems, Inc. Coagulation assays and reagents

Also Published As

Publication number Publication date
FR2822462B1 (fr) 2005-07-15
WO2002076921A1 (fr) 2002-10-03
US7208266B2 (en) 2007-04-24
HK1054737A1 (zh) 2003-12-12
JP4563648B2 (ja) 2010-10-13
RU2002131457A (ru) 2004-04-10
JP2004519507A (ja) 2004-07-02
EP1280758A1 (fr) 2003-02-05
AR034221A1 (es) 2004-02-04
US20030157582A1 (en) 2003-08-21
HUP0302136A3 (en) 2005-12-28
PL357449A1 (en) 2004-07-26
CN100432046C (zh) 2008-11-12
MXPA02011565A (es) 2004-09-06
KR20030005359A (ko) 2003-01-17
HUP0302136A2 (hu) 2003-09-29
CN1460098A (zh) 2003-12-03
CA2407779A1 (fr) 2002-10-03
FR2822462A1 (fr) 2002-09-27

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE 7A. E 8A. ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2055 DE 25/05/2010.