AR034221A1 - Derivados de acido galico, un proceso para su preparacion, composicion farmaceutica, reactivos, sistema de reactivos, uso de dichos compuestos reactivos para preparar un ensayo in vitro de la coagulacion endogena, su utilizacion en la exploracion de la coagulacion endogena, y un metodo para medir el - Google Patents

Derivados de acido galico, un proceso para su preparacion, composicion farmaceutica, reactivos, sistema de reactivos, uso de dichos compuestos reactivos para preparar un ensayo in vitro de la coagulacion endogena, su utilizacion en la exploracion de la coagulacion endogena, y un metodo para medir el

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Publication number
AR034221A1
AR034221A1 ARP020101046A ARP020101046A AR034221A1 AR 034221 A1 AR034221 A1 AR 034221A1 AR P020101046 A ARP020101046 A AR P020101046A AR P020101046 A ARP020101046 A AR P020101046A AR 034221 A1 AR034221 A1 AR 034221A1
Authority
AR
Argentina
Prior art keywords
coagulation
reagents
exploration
derivatives
prepare
Prior art date
Application number
ARP020101046A
Other languages
English (en)
Original Assignee
Stago Diagnostica
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stago Diagnostica filed Critical Stago Diagnostica
Publication of AR034221A1 publication Critical patent/AR034221A1/es

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/50—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/82—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C69/757—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
    • C07C69/88—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with esterified carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Polyethers (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fats And Perfumes (AREA)

Abstract

Derivados del ácido gálico, que comprende un compuesto de la fórmula (1), en la cual: A es seleccionado de entre el grupo consistente en las fórmulas (2), (3) ó (4); M+ representa un catión, siendo q igual a 1 ó 2, y siendo p tal que p x q = 2; R representa un compuesto de fórmula (5) ó (6), siendo m igual a 2, 3, 4 ó 5, y siendo n un número entero entre 1 y 170; o -AA1-AA2-.......-AAr-, siendo AA un aminoácido natural o exótico, y siendo r un número entero entre 1 y 10, con la condición que el compuesto no es un compuesto de fórmula (7) cuando m es 2, 3 ó 4; un proceso para su preparación, composición farmacéutica, reactivos, sistema de reactivos, uso de dichos compuestos reactivos para preparar un ensayo in vitro de la coagulación endógena, su utilización en la exploración de la coagulación endógena y un método para medir el tiempo de la tromboplastina parcial activada.
ARP020101046A 2001-03-23 2002-03-22 Derivados de acido galico, un proceso para su preparacion, composicion farmaceutica, reactivos, sistema de reactivos, uso de dichos compuestos reactivos para preparar un ensayo in vitro de la coagulacion endogena, su utilizacion en la exploracion de la coagulacion endogena, y un metodo para medir el AR034221A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0103979A FR2822462B1 (fr) 2001-03-23 2001-03-23 Composes activateurs de la coagulation endogene utilisation pour l'exploration de la coagulation endogene

Publications (1)

Publication Number Publication Date
AR034221A1 true AR034221A1 (es) 2004-02-04

Family

ID=8861494

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP020101046A AR034221A1 (es) 2001-03-23 2002-03-22 Derivados de acido galico, un proceso para su preparacion, composicion farmaceutica, reactivos, sistema de reactivos, uso de dichos compuestos reactivos para preparar un ensayo in vitro de la coagulacion endogena, su utilizacion en la exploracion de la coagulacion endogena, y un metodo para medir el

Country Status (15)

Country Link
US (1) US7208266B2 (es)
EP (1) EP1280758A1 (es)
JP (1) JP4563648B2 (es)
KR (1) KR20030005359A (es)
CN (1) CN100432046C (es)
AR (1) AR034221A1 (es)
BR (1) BR0204494A (es)
CA (1) CA2407779A1 (es)
FR (1) FR2822462B1 (es)
HK (1) HK1054737A1 (es)
HU (1) HUP0302136A3 (es)
MX (1) MXPA02011565A (es)
PL (1) PL357449A1 (es)
RU (1) RU2002131457A (es)
WO (1) WO2002076921A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7208145B2 (en) * 2002-12-31 2007-04-24 Nektar Therapeutics Al, Corporation Polymeric reagents comprising a ketone or a related functional group
DE102007062323A1 (de) * 2007-12-21 2009-06-25 Siemens Healthcare Diagnostics Products Gmbh Langzeitstabiles Thromboplastin-Reagenz
JP6577778B2 (ja) * 2015-07-30 2019-09-18 シスメックス株式会社 凝固時間の測定方法およびその装置、凝固時間測定用試薬ならびに試薬キット
CN105424945B (zh) * 2015-11-20 2018-05-18 重庆贝羿生物科技有限公司 一种凝血激活检测试剂及其制备方法与用途
KR101651605B1 (ko) * 2015-12-10 2016-08-26 대봉엘에스 주식회사 신규 페놀산류 유도체 화합물, 및 이의 용도
CN108344875B (zh) * 2017-01-22 2021-11-02 上海长岛生物技术有限公司 提高活化部分凝血活酶时间试剂对肝素敏感性的方法及用途
EP3859327A4 (en) * 2018-09-25 2022-09-07 Sekisui Medical Co., Ltd. METHOD OF MEASUREMENT OF BLOOD COAGING TIME
CN110824154A (zh) * 2019-10-15 2020-02-21 常熟常江生物技术有限公司 用于血栓弹力图仪的激活剂
CN113679039B (zh) * 2021-05-12 2023-05-09 浙江大学 一种没食子酸聚乙二醇酯蛋白载体增效剂及其制备方法与应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1565823A (en) * 1976-11-11 1980-04-23 Pilkington Brothers Ltd Coating of glass fibres
JPS60199850A (ja) * 1984-03-26 1985-10-09 Eisai Co Ltd 新規な没食子酸誘導体
DE3544338A1 (de) * 1985-12-14 1987-06-19 Hoechst Ag Peptid-derivate mit inhibitorischer wirkung auf hydroxylierende enzyme, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung
DE3750344T2 (de) * 1986-04-11 1994-12-08 Sekisui Chemical Co Ltd Beschleuniger der Aktivität von Hydrolase.
US4994192A (en) * 1990-01-16 1991-02-19 Eastman Kodak Company Amine polymers as coagulator accelerators in blood phase separation
US4979471A (en) * 1990-04-09 1990-12-25 Larry Hartshorn Animal confinement chute
AU663683B2 (en) * 1990-04-17 1995-10-19 Analytical Control Systems, Inc. Coagulation assays and reagents

Also Published As

Publication number Publication date
JP4563648B2 (ja) 2010-10-13
HK1054737A1 (zh) 2003-12-12
RU2002131457A (ru) 2004-04-10
JP2004519507A (ja) 2004-07-02
MXPA02011565A (es) 2004-09-06
PL357449A1 (en) 2004-07-26
US20030157582A1 (en) 2003-08-21
CA2407779A1 (fr) 2002-10-03
BR0204494A (pt) 2003-04-08
CN1460098A (zh) 2003-12-03
FR2822462A1 (fr) 2002-09-27
WO2002076921A1 (fr) 2002-10-03
HUP0302136A3 (en) 2005-12-28
CN100432046C (zh) 2008-11-12
HUP0302136A2 (hu) 2003-09-29
FR2822462B1 (fr) 2005-07-15
US7208266B2 (en) 2007-04-24
KR20030005359A (ko) 2003-01-17
EP1280758A1 (fr) 2003-02-05

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